REACTOME_DEPOLYMERISATION_OF_THE_NUCLEAR_LAMINA Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 LMNA Prelamin-A/C [1] -0.63[2] -1.50[3] -2.60[4] -0.38[5] -1.04[6] -1.10[7]
2 EMD Emerin [8] -1.58[9] -1.94[10] -1.95[11] -1.32[12] -1.22[13] -2.18[14]
3 CTDNEP1 CTD nuclear envelope phosphatase 1 [15] 0.26[16] -0.32[17] -0.28[18] -0.60[19] -0.48[20] -2.06[21]
4 TMPO Lamina-associated polypeptide 2, isoform alpha [22] 0.46[23] 0.92[24] 1.46[25] 1.26[26] 1.26[27] 0.67[28]
5 LPIN2 Phosphatidate phosphatase LPIN2 [29] 0.63[30] 0.95[31] 1.86[32] -0.13[33] -0.51[34] 2.50[35]
6 CCNB1 G2/mitotic-specific cyclin-B1 [36] 1.36[37] 1.28[38] 1.73[39] 0.70[40] 1.79[41] -2.47[42]
7 LMNB1 Lamin-B1 [43] 0.49[44] 0.21[45] 0.53[46] 0.41[47] 0.17[48] -2.33[49]
8 LEMD2 LEM domain-containing protein 2 [50] 0.30[51] -0.04[52] -0.66[53] 0.15[54] -0.32[55] -0.81[56]
9 LPIN1 Phosphatidate phosphatase LPIN1 [57] -2.07[58] -0.56[59] -1.37[60] -0.38[61] -1.20[62] 1.32[63]
10 CDK1 Cyclin-dependent kinase 1 [64] 0.76[65] 2.51[66] 1.51[67] 1.37[68] 2.30[69] -2.60[70]
11 CNEP1R1 Nuclear envelope phosphatase-regulatory subunit 1 [71] -0.07[72] -0.25[73] -0.57[74] -0.47[75] -0.53[76] -0.23[77]
12 PRKCA Protein kinase C alpha type [78] 2.35[79] 2.07[80] 2.70[81] 1.25[82] 1.72[83] 1.79[84]
13 LEMD3 Inner nuclear membrane protein Man1 [85] 0.41[86] 1.07[87] 1.29[88] 0.32[89] 0.91[90] 1.33[91]
14 LPIN3 Phosphatidate phosphatase LPIN3 [92] 1.09[93] 1.79[94] 0.17[95] 0.51[96] 0.21[97] 3.54[98]
15 PRKCB Protein kinase C beta type [99] -7.30[100] -6.42[101] [102] 1.58[103] -3.61[104] 3.41[105]
[1]
ref_hepatocyte LMNA
Mean 84.6
Standard deviation 77
Values 62 2.2e+02 65 42 33
[2]
HepG2 LMNA
Mean 170
Standard deviation 28
Values 1.9e+02 1.5e+02
[3]
HepG2.C3A LMNA
Mean 103
Standard deviation 24
Values 1.2e+02 86
[4]
HuH.7 LMNA
Mean 38.1
Standard deviation 0.77
Values 38 39 37
[5]
SNU475 LMNA
Mean 223
Standard deviation 30
Values 2.4e+02 2e+02
[6]
THLE LMNA
Mean 146
Standard deviation 49
Values 1.1e+02 1.8e+02
[7]
liver LMNA
Mean 61.5
Standard deviation 29
Values 59 45 1e+02 39
[8]
ref_hepatocyte EMD
Mean 16.2
Standard deviation 7.9
Values 5.7 10 25 22 19
[9]
HepG2 EMD
Mean 16.8
Standard deviation 2.7
Values 19 15
[10]
HepG2.C3A EMD
Mean 14.4
Standard deviation 1.8
Values 16 13
[11]
HuH.7 EMD
Mean 11.4
Standard deviation 1.3
Values 11 10 13
[12]
SNU475 EMD
Mean 22.2
Standard deviation 4.3
Values 25 19
[13]
THLE EMD
Mean 24.7
Standard deviation 2.2
Values 23 26
[14]
liver EMD
Mean 5.54
Standard deviation 4.4
Values 7.8 1.6 11 2.1
[15]
ref_hepatocyte CTDNEP1
Mean 13.2
Standard deviation 7.5
Values 24 5.8 7.2 16 13
[16]
HepG2 CTDNEP1
Mean 48.8
Standard deviation 7.5
Values 54 44
[17]
HepG2.C3A CTDNEP1
Mean 36.3
Standard deviation 9.7
Values 43 29
[18]
HuH.7 CTDNEP1
Mean 29.7
Standard deviation 2.2
Values 29 28 32
[19]
SNU475 CTDNEP1
Mean 29.8
Standard deviation 1.1
Values 29 31
[20]
THLE CTDNEP1
Mean 33.7
Standard deviation 3.3
Values 31 36
[21]
liver CTDNEP1
Mean 4.91
Standard deviation 2
Values 7.5 3 5.3 3.8
[22]
ref_hepatocyte TMPO
Mean 10.2
Standard deviation 6
Values 15 18 4.2 4.6 9.6
[23]
HepG2 TMPO
Mean 43.5
Standard deviation 13
Values 34 53
[24]
HepG2.C3A TMPO
Mean 66.2
Standard deviation 37
Values 40 93
[25]
HuH.7 TMPO
Mean 76.6
Standard deviation 25
Values 94 48 88
[26]
SNU475 TMPO
Mean 83.6
Standard deviation 5.9
Values 88 79
[27]
THLE TMPO
Mean 86.8
Standard deviation 22
Values 71 1e+02
[28]
liver TMPO
Mean 25.2
Standard deviation 11
Values 19 26 16 40
[29]
ref_hepatocyte LPIN2
Mean 9.55
Standard deviation 6.4
Values 4.3 6.3 6.4 10 20
[30]
HepG2 LPIN2
Mean 45.8
Standard deviation 12
Values 38 54
[31]
HepG2.C3A LPIN2
Mean 63.3
Standard deviation 20
Values 78 49
[32]
HuH.7 LPIN2
Mean 95
Standard deviation 11
Values 1.1e+02 90 87
[33]
SNU475 LPIN2
Mean 29.9
Standard deviation 6.8
Values 35 25
[34]
THLE LPIN2
Mean 23.9
Standard deviation 3
Values 22 26
[35]
liver LPIN2
Mean 84.1
Standard deviation 27
Values 72 87 56 1.2e+02
[36]
ref_hepatocyte CCNB1
Mean 8.2
Standard deviation 8.6
Values 15 20 1.8 3.1 1.3
[37]
HepG2 CCNB1
Mean 65.1
Standard deviation 21
Values 50 80
[38]
HepG2.C3A CCNB1
Mean 68.3
Standard deviation 39
Values 41 96
[39]
HuH.7 CCNB1
Mean 74.2
Standard deviation 37
Values 87 33 1e+02
[40]
SNU475 CCNB1
Mean 45.8
Standard deviation 3.3
Values 48 44
[41]
THLE CCNB1
Mean 101
Standard deviation 30
Values 80 1.2e+02
[42]
liver CCNB1
Mean 2.29
Standard deviation 1.6
Values 2.3 2.4 4.2 0.28
[43]
ref_hepatocyte LMNB1
Mean 7.95
Standard deviation 9.7
Values 25 7.4 2.1 2.1 3.3
[44]
HepG2 LMNB1
Mean 34.6
Standard deviation 12
Values 26 43
[45]
HepG2.C3A LMNB1
Mean 31.6
Standard deviation 15
Values 21 42
[46]
HuH.7 LMNB1
Mean 31.5
Standard deviation 13
Values 36 16 42
[47]
SNU475 LMNB1
Mean 36.2
Standard deviation 1.2
Values 37 35
[48]
THLE LMNB1
Mean 31.8
Standard deviation 13
Values 22 41
[49]
liver LMNB1
Mean 2.45
Standard deviation 2.4
Values 0.54 5.6 0.69 3
[50]
ref_hepatocyte LEMD2
Mean 7.82
Standard deviation 3.7
Values 6.6 4.8 14 9.3 5
[51]
HepG2 LEMD2
Mean 29.8
Standard deviation 11
Values 38 22
[52]
HepG2.C3A LEMD2
Mean 26.1
Standard deviation 12
Values 34 18
[53]
HuH.7 LEMD2
Mean 13.6
Standard deviation 2.2
Values 11 16 14
[54]
SNU475 LEMD2
Mean 29.8
Standard deviation 5.6
Values 34 26
[55]
THLE LEMD2
Mean 22.3
Standard deviation 0.74
Values 22 23
[56]
liver LEMD2
Mean 6.91
Standard deviation 4.3
Values 3.9 11 2.5 10
[57]
ref_hepatocyte LPIN1
Mean 6.88
Standard deviation 3.4
Values 3.3 5.5 12 7.4 5.9
[58]
HepG2 LPIN1
Mean 5.07
Standard deviation 1.3
Values 4.1 6
[59]
HepG2.C3A LPIN1
Mean 16
Standard deviation 7.5
Values 21 11
[60]
HuH.7 LPIN1
Mean 7.3
Standard deviation 3.1
Values 5.5 11 5.6
[61]
SNU475 LPIN1
Mean 18.1
Standard deviation 4.5
Values 21 15
[62]
THLE LPIN1
Mean 10.6
Standard deviation 1.8
Values 9.3 12
[63]
liver LPIN1
Mean 26.6
Standard deviation 4.2
Values 23 31 30 23
[64]
ref_hepatocyte CDK1
Mean 5.78
Standard deviation 6.9
Values 13 14 0.06 1.6 0.72
[65]
HepG2 CDK1
Mean 30.4
Standard deviation 14
Values 21 40
[66]
HepG2.C3A CDK1
Mean 113
Standard deviation 85
Values 53 1.7e+02
[67]
HuH.7 CDK1
Mean 45.1
Standard deviation 21
Values 55 21 60
[68]
SNU475 CDK1
Mean 51.1
Standard deviation 5
Values 48 55
[69]
THLE CDK1
Mean 101
Standard deviation 11
Values 93 1.1e+02
[70]
liver CDK1
Mean 1.48
Standard deviation 1.4
Values 1 1.4 3.4 0.013
[71]
ref_hepatocyte CNEP1R1
Mean 3.22
Standard deviation 1.4
Values 5.5 3 2.7 1.7 3.2
[72]
HepG2 CNEP1R1
Mean 9.53
Standard deviation 1.9
Values 8.2 11
[73]
HepG2.C3A CNEP1R1
Mean 9.3
Standard deviation 0.42
Values 9 9.6
[74]
HuH.7 CNEP1R1
Mean 5.95
Standard deviation 0.21
Values 5.7 6.1 6
[75]
SNU475 CNEP1R1
Mean 7.98
Standard deviation 0.88
Values 8.6 7.4
[76]
THLE CNEP1R1
Mean 7.95
Standard deviation 0.56
Values 8.3 7.6
[77]
liver CNEP1R1
Mean 4.26
Standard deviation 1.1
Values 3.4 4.6 5.7 3.4
[78]
ref_hepatocyte PRKCA
Mean 2.45
Standard deviation 2.1
Values 2.7 6 1.1 1.2 1.2
[79]
HepG2 PRKCA
Mean 38.7
Standard deviation 5.6
Values 35 43
[80]
HepG2.C3A PRKCA
Mean 35.5
Standard deviation 4.5
Values 32 39
[81]
HuH.7 PRKCA
Mean 43.7
Standard deviation 11
Values 54 44 33
[82]
SNU475 PRKCA
Mean 20
Standard deviation 4.3
Values 17 23
[83]
THLE PRKCA
Mean 28.8
Standard deviation 11
Values 21 36
[84]
liver PRKCA
Mean 13.2
Standard deviation 7.1
Values 11 17 4.7 21
[85]
ref_hepatocyte LEMD3
Mean 2.42
Standard deviation 0.98
Values 3.7 2.9 2.5 1.1 1.9
[86]
HepG2 LEMD3
Mean 9.96
Standard deviation 2.4
Values 8.3 12
[87]
HepG2.C3A LEMD3
Mean 17.5
Standard deviation 1.1
Values 17 18
[88]
HuH.7 LEMD3
Mean 16.2
Standard deviation 1.6
Values 17 17 14
[89]
SNU475 LEMD3
Mean 10.4
Standard deviation 0.91
Values 11 9.7
[90]
THLE LEMD3
Mean 16.2
Standard deviation 3.6
Values 14 19
[91]
liver LEMD3
Mean 9.48
Standard deviation 3
Values 8.1 12 5.9 12
[92]
ref_hepatocyte LPIN3
Mean 1.56
Standard deviation 0.32
Values 1.8 1 1.7 1.8 1.5
[93]
HepG2 LPIN3
Mean 10.2
Standard deviation 0.35
Values 10 10
[94]
HepG2.C3A LPIN3
Mean 18.5
Standard deviation 4.3
Values 22 15
[95]
HuH.7 LPIN3
Mean 4.79
Standard deviation 1.8
Values 3.1 6.7 4.6
[96]
SNU475 LPIN3
Mean 7.59
Standard deviation 4.2
Values 11 4.6
[97]
THLE LPIN3
Mean 6.41
Standard deviation 1.1
Values 7.2 5.6
[98]
liver LPIN3
Mean 28.1
Standard deviation 23
Values 58 9.4 34 11
[99]
ref_hepatocyte PRKCB
Mean 0.255
Standard deviation 0.29
Values 0 0 0.4 0.2 0.67
[100]
HepG2 PRKCB
Mean 0.00501
Standard deviation 0.001
Values 0.0057 0.0043
[101]
HepG2.C3A PRKCB
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[102]
HuH.7 PRKCB
Mean 0
Standard deviation 0
Values 0 0 0
[103]
SNU475 PRKCB
Mean 2.62
Standard deviation 2.8
Values 0.61 4.6
[104]
THLE PRKCB
Mean 0.0742
Standard deviation 0.037
Values 0.1 0.048
[105]
liver PRKCB
Mean 4.2
Standard deviation 2.1
Values 2.7 6.8 2.2 5