REACTOME_DEGRADATION_OF_DVL | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | UBB | Polyubiquitin-B | [1] | -1.08[2] | -1.13[3] | -0.98[4] | -1.32[5] | -0.96[6] | -0.39[7] |
2 | RPS27A | Ubiquitin-40S ribosomal protein S27a | [8] | [9] | [10] | [11] | [12] | [13] | [14] |
3 | UBC | Polyubiquitin-C | [15] | -0.64[16] | -0.38[17] | -0.61[18] | -0.47[19] | -0.58[20] | 0.06[21] |
4 | PSME1 | Proteasome activator complex subunit 1 | [22] | -0.41[23] | -1.97[24] | -1.58[25] | -1.19[26] | -1.80[27] | -0.89[28] |
5 | PSME2 | Proteasome activator complex subunit 2 | [29] | -0.22[30] | -1.59[31] | -1.67[32] | -0.97[33] | -1.34[34] | -0.52[35] |
6 | PSMA7 | Proteasome subunit alpha type-7 | [36] | 0.73[37] | 0.88[38] | -0.43[39] | 0.65[40] | 0.14[41] | 0.51[42] |
7 | PSMB1 | Proteasome subunit beta type-1 | [43] | 0.28[44] | 0.43[45] | -0.62[46] | -0.59[47] | 0.10[48] | 0.34[49] |
8 | PSMB3 | Proteasome subunit beta type-3 | [50] | -0.20[51] | -0.95[52] | 0.10[53] | -0.61[54] | -0.81[55] | 0.05[56] |
9 | PSMB4 | Proteasome subunit beta type-4 | [57] | 0.04[58] | 0.25[59] | 0.40[60] | 0.82[61] | 0.73[62] | -0.28[63] |
10 | PSMB7 | Proteasome subunit beta type-7 | [64] | -0.90[65] | -0.85[66] | -0.70[67] | -0.96[68] | -0.59[69] | -0.72[70] |
11 | PSMB5 | Proteasome subunit beta type-5 | [71] | 1.50[72] | 0.11[73] | 0.06[74] | -0.24[75] | -0.03[76] | -0.25[77] |
12 | PSMA6 | Proteasome subunit alpha type-6 | [78] | 1.62[79] | 0.39[80] | 0.34[81] | 0.29[82] | 0.23[83] | -0.16[84] |
13 | PSMA4 | Proteasome subunit alpha type-4 | [85] | -0.31[86] | 0.40[87] | 0.22[88] | 0.59[89] | 0.35[90] | -0.24[91] |
14 | PSMC3 | 26S proteasome regulatory subunit 6A | [92] | -0.34[93] | -0.36[94] | 0.28[95] | -0.60[96] | -0.48[97] | 0.23[98] |
15 | PSMA3 | Proteasome subunit alpha type-3 | [99] | -0.93[100] | 0.12[101] | -0.53[102] | 0.14[103] | -0.38[104] | 0.01[105] |
16 | PSMB6 | Proteasome subunit beta type-6 | [106] | -0.38[107] | -0.18[108] | -0.01[109] | -0.41[110] | -0.74[111] | 0.16[112] |
17 | PSMA2 | Proteasome subunit alpha type-2 | [113] | -0.46[114] | 0.54[115] | 0.90[116] | 0.09[117] | 0.39[118] | 0.39[119] |
18 | PSMD4 | 26S proteasome non-ATPase regulatory subunit 4 | [120] | 0.05[121] | 0.12[122] | 0.34[123] | 0.79[124] | 0.19[125] | 0.06[126] |
19 | PSMD7 | 26S proteasome non-ATPase regulatory subunit 7 | [127] | -0.03[128] | 0.39[129] | 0.28[130] | -0.29[131] | 0.11[132] | -0.11[133] |
20 | PSMD8 | 26S proteasome non-ATPase regulatory subunit 8 | [134] | 0.14[135] | 0.43[136] | 0.59[137] | -0.02[138] | 0.67[139] | -0.08[140] |
21 | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2 | [141] | 1.67[142] | 0.90[143] | 0.99[144] | 1.09[145] | 2.32[146] | 0.95[147] |
22 | PSMC1 | 26S proteasome regulatory subunit 4 | [148] | -0.01[149] | 0.11[150] | -0.52[151] | 1.28[152] | 0.73[153] | 0.11[154] |
23 | PSMA1 | Proteasome subunit alpha type-1 | [155] | 0.18[156] | 0.62[157] | 0.70[158] | 0.85[159] | 0.29[160] | 0.60[161] |
24 | UBA52 | Ubiquitin-60S ribosomal protein L40 | [162] | 1.80[163] | 1.86[164] | 2.90[165] | 0.93[166] | 1.65[167] | 0.83[168] |
25 | PSMC5 | 26S proteasome regulatory subunit 8 | [169] | 0.50[170] | 0.44[171] | 0.54[172] | 0.26[173] | 0.61[174] | 0.37[175] |
26 | RBX1 | E3 ubiquitin-protein ligase RBX1 | [176] | -0.94[177] | -0.36[178] | -0.47[179] | -1.25[180] | -0.92[181] | -0.61[182] |
27 | PSMD3 | 26S proteasome non-ATPase regulatory subunit 3 | [183] | 0.89[184] | 0.43[185] | 1.05[186] | 0.79[187] | 0.95[188] | 0.08[189] |
28 | PSMB8 | Proteasome subunit beta type-8 | [190] | -1.50[191] | -2.05[192] | -9.24[193] | 0.77[194] | -0.61[195] | -0.61[196] |
29 | PSMD14 | 26S proteasome non-ATPase regulatory subunit 14 | [197] | 0.07[198] | 0.72[199] | 1.00[200] | 0.66[201] | 0.62[202] | -0.06[203] |
30 | PSMC4 | 26S proteasome regulatory subunit 6B | [204] | 0.50[205] | 0.57[206] | 0.53[207] | 0.28[208] | 0.33[209] | 0.42[210] |
31 | PSMD6 | 26S proteasome non-ATPase regulatory subunit 6 | [211] | -0.66[212] | -0.13[213] | -1.19[214] | -0.34[215] | 0.40[216] | -0.17[217] |
32 | PSMD13 | 26S proteasome non-ATPase regulatory subunit 13 | [218] | 0.54[219] | 0.70[220] | 1.22[221] | 0.72[222] | 0.16[223] | 0.01[224] |
33 | PSMD12 | 26S proteasome non-ATPase regulatory subunit 12 | [225] | -0.28[226] | -0.15[227] | -0.44[228] | 0.34[229] | 0.34[230] | -0.07[231] |
34 | PSMC6 | 26S proteasome regulatory subunit 10B | [232] | 0.02[233] | 1.64[234] | 0.48[235] | 0.70[236] | 0.56[237] | 0.59[238] |
35 | PSMD11 | 26S proteasome non-ATPase regulatory subunit 11 | [239] | 0.90[240] | 0.56[241] | 1.17[242] | 1.10[243] | 1.19[244] | 1.41[245] |
36 | PSMC2 | 26S proteasome regulatory subunit 7 | [246] | 0.65[247] | 1.10[248] | 0.90[249] | 1.50[250] | 1.26[251] | 1.47[252] |
37 | PSME3 | Proteasome activator complex subunit 3 | [253] | 1.88[254] | 1.65[255] | 1.35[256] | 1.52[257] | 1.72[258] | 1.03[259] |
38 | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1 | [260] | 1.64[261] | 2.01[262] | 1.91[263] | 2.33[264] | 2.27[265] | 2.22[266] |
39 | PSMB10 | Proteasome subunit beta type-10 | [267] | -1.08[268] | -0.44[269] | -2.30[270] | 0.12[271] | -1.12[272] | 0.07[273] |
40 | PSMA5 | Proteasome subunit alpha type-5 | [274] | 1.97[275] | 2.44[276] | 2.03[277] | 2.38[278] | 1.87[279] | 2.06[280] |
41 | PSMF1 | Proteasome inhibitor PI31 subunit | [281] | 2.35[282] | 2.44[283] | 1.27[284] | 1.39[285] | 1.08[286] | 2.00[287] |
42 | PSMB2 | Proteasome subunit beta type-2 | [288] | 2.13[289] | 1.91[290] | 2.32[291] | 2.69[292] | 2.60[293] | 2.54[294] |
43 | PSMB9 | Proteasome subunit beta type-9 | [295] | -1.88[296] | -4.45[297] | -6.74[298] | 1.94[299] | -0.40[300] | -0.35[301] |
44 | PSMD9 | 26S proteasome non-ATPase regulatory subunit 9 | [302] | 0.51[303] | 1.04[304] | 0.08[305] | 0.56[306] | 0.93[307] | 0.87[308] |
45 | DVL1 | Segment polarity protein dishevelled homolog DVL-1 | [309] | 1.92[310] | 2.53[311] | 1.41[312] | 1.53[313] | 1.47[314] | 0.73[315] |
46 | PSMD10 | 26S proteasome non-ATPase regulatory subunit 10 | [316] | 1.06[317] | 1.43[318] | 1.48[319] | 2.23[320] | 1.48[321] | 0.86[322] |
47 | PSME4 | Proteasome activator complex subunit 4 | [323] | 2.59[324] | 3.55[325] | 3.57[326] | 2.79[327] | 2.68[328] | 3.13[329] |
48 | KLHL12 | Kelch-like protein 12 | [330] | 1.61[331] | 1.36[332] | 1.74[333] | 2.52[334] | 1.94[335] | 1.72[336] |
49 | PSMD5 | 26S proteasome non-ATPase regulatory subunit 5 | [337] | 1.48[338] | 1.08[339] | 2.66[340] | 2.62[341] | 2.63[342] | 2.31[343] |
50 | DVL3 | Segment polarity protein dishevelled homolog DVL-3 | [344] | 2.61[345] | 2.97[346] | 2.37[347] | 2.93[348] | 2.91[349] | 1.80[350] |
51 | CUL3 | Cullin-3 | [351] | 1.73[352] | 2.80[353] | 2.52[354] | 2.92[355] | 2.91[356] | 2.43[357] |
52 | DVL2 | Segment polarity protein dishevelled homolog DVL-2 | [358] | 3.24[359] | 3.14[360] | 4.12[361] | 3.68[362] | 3.23[363] | 1.50[364] |
53 | DACT1 | Dapper homolog 1 | [365] | -3.35[366] | -3.59[367] | -3.56[368] | 5.08[369] | 4.10[370] | 4.94[371] |
54 | HECW1 | E3 ubiquitin-protein ligase HECW1 | [372] | 2.02[373] | 2.36[374] | 8.41[375] | 10.24[376] | 3.41[377] | 2.04[378] |
55 | PSMB11 | Proteasome subunit beta type-11 | [379] | [380] | [381] | [382] | [383] | [384] | [385] |
56 | PSMA8 | Proteasome subunit alpha type-7-like | [386] | [387] | [388] | [389] | [390] | [391] | [392] |
57 | SEM1 | Putative protein SEM1, isoform 2 | [393] | [394] | [395] | [396] | [397] | [398] | [399] |