REACTOME_DEGRADATION_OF_CYSTEINE_AND_HOMOCYSTEINE Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 TST Thiosulfate sulfurtransferase [1] -2.58[2] -1.61[3] -1.14[4] -3.66[5] -3.32[6] -0.91[7]
2 MPST 3-mercaptopyruvate sulfurtransferase [8] 0.07[9] 0.62[10] 0.74[11] -1.51[12] -1.57[13] -0.11[14]
3 CDO1 Cysteine dioxygenase type 1 [15] -4.47[16] -6.28[17] -4.41[18] -5.10[19] -10.91[20] 0.29[21]
4 GOT2 Aspartate aminotransferase, mitochondrial [22] 1.37[23] 0.68[24] 0.76[25] 1.48[26] 2.01[27] 1.14[28]
5 TXN2 Thioredoxin, mitochondrial [29] 0.55[30] 0.47[31] 0.67[32] 0.91[33] 0.44[34] -0.16[35]
6 TSTD1 Thiosulfate:glutathione sulfurtransferase [36] -11.90[37] -9.17[38] -10.15[39] -0.92[40] -0.96[41] -1.67[42]
7 CTH Cystathionine gamma-lyase [43] -0.64[44] -1.64[45] 0.14[46] -1.37[47] -1.39[48] 0.36[49]
8 SLC25A10 Mitochondrial dicarboxylate carrier [50] 2.39[51] 1.94[52] 0.14[53] 1.25[54] 1.14[55] -0.08[56]
9 SUOX Sulfite oxidase, mitochondrial [57] -0.12[58] 0.55[59] 0.54[60] 1.12[61] 0.19[62] 0.55[63]
10 ETHE1 Persulfide dioxygenase ETHE1, mitochondrial [64] 0.43[65] 1.46[66] 1.75[67] 0.39[68] 1.16[69] -0.38[70]
11 CSAD Cysteine sulfinic acid decarboxylase [71] -0.91[72] 0.60[73] -0.35[74] 1.36[75] 0.47[76] 1.06[77]
12 ADO 2-aminoethanethiol dioxygenase [78] 3.41[79] 3.36[80] 2.51[81] 4.97[82] 4.56[83] 0.61[84]
13 SQOR Sulfide:quinone oxidoreductase, mitochondrial [85] [86] [87] [88] [89] [90] [91]
14 GADL1 Acidic amino acid decarboxylase GADL1 [92] [93] [94] [95] [96] [97] [98]
[1]
ref_hepatocyte TST
Mean 157
Standard deviation 2e+02
Values 15 23 14 3.1e+02 4.2e+02
[2]
HepG2 TST
Mean 16.8
Standard deviation 3.9
Values 20 14
[3]
HepG2.C3A TST
Mean 35.1
Standard deviation 17
Values 47 23
[4]
HuH.7 TST
Mean 50
Standard deviation 20
Values 54 29 68
[5]
SNU475 TST
Mean 2.44
Standard deviation 0.11
Values 2.4 2.5
[6]
THLE TST
Mean 4.99
Standard deviation 0.43
Values 4.7 5.3
[7]
liver TST
Mean 88.8
Standard deviation 68
Values 1.8e+02 38 95 39
[8]
ref_hepatocyte MPST
Mean 86.1
Standard deviation 86
Values 18 22 31 1.7e+02 1.9e+02
[9]
HepG2 MPST
Mean 58.1
Standard deviation 26
Values 77 39
[10]
HepG2.C3A MPST
Mean 90.3
Standard deviation 48
Values 1.2e+02 56
[11]
HuH.7 MPST
Mean 101
Standard deviation 15
Values 86 1e+02 1.2e+02
[12]
SNU475 MPST
Mean 5.95
Standard deviation 1.1
Values 6.7 5.1
[13]
THLE MPST
Mean 9.2
Standard deviation 1.6
Values 8.1 10
[14]
liver MPST
Mean 84.9
Standard deviation 66
Values 1.6e+02 26 1.2e+02 35
[15]
ref_hepatocyte CDO1
Mean 64.7
Standard deviation 88
Values 1.9 6.3 1.9 1.2e+02 1.9e+02
[16]
HepG2 CDO1
Mean 1.88
Standard deviation 1.5
Values 0.83 2.9
[17]
HepG2.C3A CDO1
Mean 0.569
Standard deviation 0.38
Values 0.3 0.84
[18]
HuH.7 CDO1
Mean 2.14
Standard deviation 0.25
Values 2 2.4 2
[19]
SNU475 CDO1
Mean 0.371
Standard deviation 0.24
Values 0.2 0.54
[20]
THLE CDO1
Mean 0.0106
Standard deviation 0.015
Values 0 0.021
[21]
liver CDO1
Mean 83.9
Standard deviation 21
Values 87 76 1.1e+02 62
[22]
ref_hepatocyte GOT2
Mean 58.1
Standard deviation 35
Values 32 39 29 86 1e+02
[23]
HepG2 GOT2
Mean 96.4
Standard deviation 0.81
Values 96 97
[24]
HepG2.C3A GOT2
Mean 63.2
Standard deviation 7.6
Values 58 69
[25]
HuH.7 GOT2
Mean 69
Standard deviation 13
Values 80 55 72
[26]
SNU475 GOT2
Mean 31.9
Standard deviation 2.4
Values 34 30
[27]
THLE GOT2
Mean 74.4
Standard deviation 6.4
Values 70 79
[28]
liver GOT2
Mean 136
Standard deviation 87
Values 1.8e+02 77 2.4e+02 50
[29]
ref_hepatocyte TXN2
Mean 46.2
Standard deviation 26
Values 15 28 45 73 70
[30]
HepG2 TXN2
Mean 43.4
Standard deviation 6.9
Values 39 48
[31]
HepG2.C3A TXN2
Mean 43.5
Standard deviation 6.3
Values 39 48
[32]
HuH.7 TXN2
Mean 51.9
Standard deviation 9.4
Values 56 41 59
[33]
SNU475 TXN2
Mean 17.1
Standard deviation 4.9
Values 21 14
[34]
THLE TXN2
Mean 19.9
Standard deviation 6.3
Values 15 24
[35]
liver TXN2
Mean 44
Standard deviation 43
Values 81 9 81 5
[36]
ref_hepatocyte TSTD1
Mean 25.5
Standard deviation 22
Values 0 17 17 37 57
[37]
HepG2 TSTD1
Mean 0.00429
Standard deviation 0.0061
Values 0 0.0086
[38]
HepG2.C3A TSTD1
Mean 0.0302
Standard deviation 0.012
Values 0.039 0.021
[39]
HuH.7 TSTD1
Mean 0.0158
Standard deviation 0.014
Values 0 0.019 0.028
[40]
SNU475 TSTD1
Mean 2.66
Standard deviation 1.1
Values 3.5 1.9
[41]
THLE TSTD1
Mean 4.16
Standard deviation 0.21
Values 4.3 4
[42]
liver TSTD1
Mean 8.54
Standard deviation 8.9
Values 11 2.6 20 0.66
[43]
ref_hepatocyte CTH
Mean 20.3
Standard deviation 26
Values 1.2 1.6 9.9 24 64
[44]
HepG2 CTH
Mean 8.35
Standard deviation 5.8
Values 12 4.2
[45]
HepG2.C3A CTH
Mean 4.42
Standard deviation 2.6
Values 6.3 2.6
[46]
HuH.7 CTH
Mean 15.7
Standard deviation 1.2
Values 16 17 14
[47]
SNU475 CTH
Mean 1.54
Standard deviation 0.042
Values 1.5 1.6
[48]
THLE CTH
Mean 2.44
Standard deviation 0.065
Values 2.5 2.4
[49]
liver CTH
Mean 27.6
Standard deviation 15
Values 38 17 43 13
[50]
ref_hepatocyte SLC25A10
Mean 20.2
Standard deviation 13
Values 17 12 5.7 32 35
[51]
HepG2 SLC25A10
Mean 68
Standard deviation 10
Values 61 75
[52]
HepG2.C3A SLC25A10
Mean 52.9
Standard deviation 15
Values 43 63
[53]
HuH.7 SLC25A10
Mean 15.6
Standard deviation 8.3
Values 21 6 20
[54]
SNU475 SLC25A10
Mean 9.47
Standard deviation 0.77
Values 8.9 10
[55]
THLE SLC25A10
Mean 14.1
Standard deviation 3.4
Values 12 17
[56]
liver SLC25A10
Mean 20.3
Standard deviation 8.1
Values 31 11 21 19
[57]
ref_hepatocyte SUOX
Mean 13.3
Standard deviation 14
Values 4.8 3 3.4 23 32
[58]
HepG2 SUOX
Mean 7.86
Standard deviation 2.5
Values 6.1 9.6
[59]
HepG2.C3A SUOX
Mean 13.3
Standard deviation 0.31
Values 13 13
[60]
HuH.7 SUOX
Mean 13.6
Standard deviation 3.1
Values 15 10 16
[61]
SNU475 SUOX
Mean 5.68
Standard deviation 0.5
Values 6 5.3
[62]
THLE SUOX
Mean 4.83
Standard deviation 0.96
Values 4.1 5.5
[63]
liver SUOX
Mean 20.8
Standard deviation 9.2
Values 30 12 28 13
[64]
ref_hepatocyte ETHE1
Mean 12.3
Standard deviation 12
Values 2.2 5.4 3.2 26 25
[65]
HepG2 ETHE1
Mean 10.6
Standard deviation 2
Values 12 9.2
[66]
HepG2.C3A ETHE1
Mean 23
Standard deviation 2
Values 24 22
[67]
HuH.7 ETHE1
Mean 29.1
Standard deviation 4.4
Values 27 26 34
[68]
SNU475 ETHE1
Mean 3.16
Standard deviation 0.71
Values 2.7 3.7
[69]
THLE ETHE1
Mean 8.73
Standard deviation 0.34
Values 8.5 9
[70]
liver ETHE1
Mean 9.99
Standard deviation 6.6
Values 14 4.1 17 4.8
[71]
ref_hepatocyte CSAD
Mean 7.55
Standard deviation 9.6
Values 1.3 0.97 0.95 12 22
[72]
HepG2 CSAD
Mean 2.57
Standard deviation 0.32
Values 2.3 2.8
[73]
HepG2.C3A CSAD
Mean 7.82
Standard deviation 2
Values 9.2 6.4
[74]
HuH.7 CSAD
Mean 4.16
Standard deviation 1.3
Values 3 3.9 5.5
[75]
SNU475 CSAD
Mean 3.82
Standard deviation 1.3
Values 4.7 2.9
[76]
THLE CSAD
Mean 3.32
Standard deviation 0.99
Values 4 2.6
[77]
liver CSAD
Mean 16.7
Standard deviation 6.4
Values 20 14 24 9.5
[78]
ref_hepatocyte ADO
Mean 2.23
Standard deviation 1.3
Values 4.3 1.1 2.8 1.6 1.4
[79]
HepG2 ADO
Mean 15.1
Standard deviation 0.042
Values 15 15
[80]
HepG2.C3A ADO
Mean 15.5
Standard deviation 0.09
Values 15 16
[81]
HuH.7 ADO
Mean 8.94
Standard deviation 1.1
Values 8.2 8.4 10
[82]
SNU475 ADO
Mean 13.7
Standard deviation 1.3
Values 13 15
[83]
THLE ADO
Mean 16.7
Standard deviation 2.3
Values 15 18
[84]
liver ADO
Mean 3.6
Standard deviation 1.6
Values 2.4 5 2 5.1
[85]
ref_hepatocyte SQOR
Missing
[86]
HepG2 SQOR
Missing
[87]
HepG2.C3A SQOR
Missing
[88]
HuH.7 SQOR
Missing
[89]
SNU475 SQOR
Missing
[90]
THLE SQOR
Missing
[91]
liver SQOR
Missing
[92]
ref_hepatocyte GADL1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[93]
HepG2 GADL1
Mean 0.00643
Standard deviation 0.0091
Values 0 0.013
[94]
HepG2.C3A GADL1
Mean 0
Standard deviation 0
Values 0 0
[95]
HuH.7 GADL1
Mean 0
Standard deviation 0
Values 0 0 0
[96]
SNU475 GADL1
Mean 3.16
Standard deviation 2.5
Values 4.9 1.4
[97]
THLE GADL1
Mean 0
Standard deviation 0
Values 0 0
[98]
liver GADL1
Mean 0.00357
Standard deviation 0.0071
Values 0 0.014 0 0