REACTOME_DEGRADATION_OF_AXIN | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | UBB | Polyubiquitin-B | [1] | -1.11[2] | -1.13[3] | -0.99[4] | -1.30[5] | -0.95[6] | -0.41[7] |
2 | RPS27A | Ubiquitin-40S ribosomal protein S27a | [8] | [9] | [10] | [11] | [12] | [13] | [14] |
3 | UBC | Polyubiquitin-C | [15] | -0.66[16] | -0.38[17] | -0.62[18] | -0.45[19] | -0.57[20] | 0.04[21] |
4 | PSME1 | Proteasome activator complex subunit 1 | [22] | -0.43[23] | -1.97[24] | -1.59[25] | -1.17[26] | -1.80[27] | -0.91[28] |
5 | PSME2 | Proteasome activator complex subunit 2 | [29] | -0.25[30] | -1.59[31] | -1.68[32] | -0.95[33] | -1.33[34] | -0.53[35] |
6 | PSMA7 | Proteasome subunit alpha type-7 | [36] | 0.70[37] | 0.88[38] | -0.44[39] | 0.68[40] | 0.14[41] | 0.49[42] |
7 | PSMB1 | Proteasome subunit beta type-1 | [43] | 0.25[44] | 0.43[45] | -0.63[46] | -0.57[47] | 0.10[48] | 0.33[49] |
8 | PSMB3 | Proteasome subunit beta type-3 | [50] | -0.23[51] | -0.95[52] | 0.09[53] | -0.59[54] | -0.80[55] | 0.03[56] |
9 | PSMB4 | Proteasome subunit beta type-4 | [57] | 0.01[58] | 0.25[59] | 0.39[60] | 0.84[61] | 0.74[62] | -0.30[63] |
10 | PSMB7 | Proteasome subunit beta type-7 | [64] | -0.93[65] | -0.85[66] | -0.71[67] | -0.94[68] | -0.59[69] | -0.74[70] |
11 | PSMB5 | Proteasome subunit beta type-5 | [71] | 1.47[72] | 0.11[73] | 0.05[74] | -0.21[75] | -0.03[76] | -0.26[77] |
12 | PSMA6 | Proteasome subunit alpha type-6 | [78] | 1.60[79] | 0.39[80] | 0.33[81] | 0.32[82] | 0.24[83] | -0.18[84] |
13 | PSMA4 | Proteasome subunit alpha type-4 | [85] | -0.33[86] | 0.40[87] | 0.21[88] | 0.62[89] | 0.35[90] | -0.26[91] |
14 | PSMC3 | 26S proteasome regulatory subunit 6A | [92] | -0.37[93] | -0.36[94] | 0.27[95] | -0.58[96] | -0.47[97] | 0.21[98] |
15 | PSMA3 | Proteasome subunit alpha type-3 | [99] | -0.95[100] | 0.12[101] | -0.54[102] | 0.16[103] | -0.37[104] | -0.01[105] |
16 | PSMB6 | Proteasome subunit beta type-6 | [106] | -0.41[107] | -0.18[108] | -0.03[109] | -0.38[110] | -0.74[111] | 0.15[112] |
17 | PSMA2 | Proteasome subunit alpha type-2 | [113] | -0.49[114] | 0.54[115] | 0.89[116] | 0.11[117] | 0.40[118] | 0.37[119] |
18 | PSMD4 | 26S proteasome non-ATPase regulatory subunit 4 | [120] | 0.03[121] | 0.12[122] | 0.33[123] | 0.82[124] | 0.19[125] | 0.05[126] |
19 | PSMD7 | 26S proteasome non-ATPase regulatory subunit 7 | [127] | -0.06[128] | 0.39[129] | 0.26[130] | -0.27[131] | 0.12[132] | -0.13[133] |
20 | PSMD8 | 26S proteasome non-ATPase regulatory subunit 8 | [134] | 0.11[135] | 0.43[136] | 0.58[137] | 0.01[138] | 0.68[139] | -0.10[140] |
21 | PSMD2 | 26S proteasome non-ATPase regulatory subunit 2 | [141] | 1.64[142] | 0.90[143] | 0.98[144] | 1.11[145] | 2.32[146] | 0.93[147] |
22 | PSMC1 | 26S proteasome regulatory subunit 4 | [148] | -0.03[149] | 0.11[150] | -0.53[151] | 1.30[152] | 0.74[153] | 0.09[154] |
23 | PSMA1 | Proteasome subunit alpha type-1 | [155] | 0.15[156] | 0.62[157] | 0.69[158] | 0.87[159] | 0.29[160] | 0.58[161] |
24 | UBA52 | Ubiquitin-60S ribosomal protein L40 | [162] | 1.77[163] | 1.86[164] | 2.89[165] | 0.95[166] | 1.65[167] | 0.81[168] |
25 | PSMC5 | 26S proteasome regulatory subunit 8 | [169] | 0.47[170] | 0.44[171] | 0.53[172] | 0.28[173] | 0.61[174] | 0.35[175] |
26 | PSMD3 | 26S proteasome non-ATPase regulatory subunit 3 | [176] | 0.86[177] | 0.43[178] | 1.04[179] | 0.82[180] | 0.95[181] | 0.06[182] |
27 | PSMB8 | Proteasome subunit beta type-8 | [183] | -1.53[184] | -2.05[185] | -9.25[186] | 0.79[187] | -0.61[188] | -0.62[189] |
28 | PSMD14 | 26S proteasome non-ATPase regulatory subunit 14 | [190] | 0.04[191] | 0.72[192] | 0.99[193] | 0.68[194] | 0.62[195] | -0.08[196] |
29 | PSMC4 | 26S proteasome regulatory subunit 6B | [197] | 0.47[198] | 0.57[199] | 0.52[200] | 0.31[201] | 0.34[202] | 0.40[203] |
30 | PSMD6 | 26S proteasome non-ATPase regulatory subunit 6 | [204] | -0.69[205] | -0.13[206] | -1.20[207] | -0.32[208] | 0.41[209] | -0.19[210] |
31 | PSMD13 | 26S proteasome non-ATPase regulatory subunit 13 | [211] | 0.51[212] | 0.70[213] | 1.21[214] | 0.74[215] | 0.16[216] | -0.01[217] |
32 | PSMD12 | 26S proteasome non-ATPase regulatory subunit 12 | [218] | -0.31[219] | -0.15[220] | -0.45[221] | 0.36[222] | 0.34[223] | -0.08[224] |
33 | PSMC6 | 26S proteasome regulatory subunit 10B | [225] | -0.01[226] | 1.64[227] | 0.47[228] | 0.72[229] | 0.56[230] | 0.57[231] |
34 | PSMD11 | 26S proteasome non-ATPase regulatory subunit 11 | [232] | 0.87[233] | 0.56[234] | 1.16[235] | 1.13[236] | 1.20[237] | 1.39[238] |
35 | PSMC2 | 26S proteasome regulatory subunit 7 | [239] | 0.63[240] | 1.10[241] | 0.89[242] | 1.52[243] | 1.26[244] | 1.45[245] |
36 | PSME3 | Proteasome activator complex subunit 3 | [246] | 1.85[247] | 1.65[248] | 1.34[249] | 1.55[250] | 1.73[251] | 1.01[252] |
37 | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1 | [253] | 1.61[254] | 2.01[255] | 1.90[256] | 2.35[257] | 2.27[258] | 2.20[259] |
38 | PSMB10 | Proteasome subunit beta type-10 | [260] | -1.11[261] | -0.44[262] | -2.32[263] | 0.14[264] | -1.11[265] | 0.05[266] |
39 | PSMA5 | Proteasome subunit alpha type-5 | [267] | 1.94[268] | 2.44[269] | 2.02[270] | 2.40[271] | 1.88[272] | 2.04[273] |
40 | PSMF1 | Proteasome inhibitor PI31 subunit | [274] | 2.32[275] | 2.44[276] | 1.26[277] | 1.41[278] | 1.09[279] | 1.98[280] |
41 | PSMB2 | Proteasome subunit beta type-2 | [281] | 2.10[282] | 1.91[283] | 2.31[284] | 2.71[285] | 2.61[286] | 2.53[287] |
42 | PSMB9 | Proteasome subunit beta type-9 | [288] | -1.91[289] | -4.45[290] | -6.75[291] | 1.96[292] | -0.40[293] | -0.37[294] |
43 | PSMD9 | 26S proteasome non-ATPase regulatory subunit 9 | [295] | 0.48[296] | 1.04[297] | 0.07[298] | 0.58[299] | 0.94[300] | 0.86[301] |
44 | PSMD10 | 26S proteasome non-ATPase regulatory subunit 10 | [302] | 1.03[303] | 1.43[304] | 1.46[305] | 2.26[306] | 1.49[307] | 0.84[308] |
45 | PSME4 | Proteasome activator complex subunit 4 | [309] | 2.56[310] | 3.55[311] | 3.56[312] | 2.81[313] | 2.69[314] | 3.11[315] |
46 | PSMD5 | 26S proteasome non-ATPase regulatory subunit 5 | [316] | 1.45[317] | 1.08[318] | 2.65[319] | 2.64[320] | 2.64[321] | 2.29[322] |
47 | RNF146 | E3 ubiquitin-protein ligase RNF146 | [323] | 1.04[324] | 1.69[325] | 0.91[326] | 2.09[327] | 1.68[328] | 1.92[329] |
48 | AXIN1 | Axin-1 | [330] | 2.44[331] | 2.94[332] | 1.37[333] | -7.22[334] | 1.52[335] | 0.82[336] |
49 | AXIN2 | Axin-2 | [337] | 4.56[338] | 2.34[339] | -1.72[340] | 0.39[341] | -0.09[342] | -0.88[343] |
50 | TNKS2 | Tankyrase-2 | [344] | 2.80[345] | 4.06[346] | 4.51[347] | 3.61[348] | 3.68[349] | 3.88[350] |
51 | SMURF2 | E3 ubiquitin-protein ligase SMURF2 | [351] | 2.81[352] | 3.01[353] | 1.51[354] | 2.67[355] | 3.00[356] | 1.60[357] |
52 | TNKS | Tankyrase-1 | [358] | 3.82[359] | 4.33[360] | 5.29[361] | 3.09[362] | 4.01[363] | 4.67[364] |
53 | PSMA8 | Proteasome subunit alpha type-7-like | [365] | [366] | [367] | [368] | [369] | [370] | [371] |
54 | SEM1 | Putative protein SEM1, isoform 2 | [372] | [373] | [374] | [375] | [376] | [377] | [378] |
55 | PSMB11 | Proteasome subunit beta type-11 | [379] | [380] | [381] | [382] | [383] | [384] | [385] |