REACTOME_DEFECTS_OF_CONTACT_ACTIVATION_SYSTEM_CAS_AND_KALLIKREIN_KININ_SYSTEM_KKS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 SERPING1 Plasma protease C1 inhibitor [1] -3.63[2] -13.08[3] -4.90[4] -5.13[5] -0.11[6] -0.39[7]
2 F2 Prothrombin [8] 1.25[9] 1.20[10] 1.44[11] -4.91[12] -5.59[13] 0.18[14]
3 F12 Coagulation factor XII [15] -3.73[16] -1.77[17] -1.68[18] -8.00[19] -3.67[20] -0.56[21]
4 F9 Coagulation factor IX [22] -9.59[23] [24] -11.94[25] [26] [27] 1.12[28]
5 F10 Coagulation factor X [29] 1.77[30] 2.17[31] 0.57[32] -1.89[33] -4.69[34] -0.07[35]
6 KLKB1 Plasma kallikrein [36] -5.15[37] -2.80[38] -3.95[39] -6.54[40] -5.51[41] 0.17[42]
7 TPST2 Protein-tyrosine sulfotransferase 2 [43] 1.09[44] 0.63[45] 1.08[46] 4.30[47] 2.21[48] 0.36[49]
8 F11 Coagulation factor XI [50] 0.85[51] 2.61[52] -1.63[53] -8.34[54] -7.48[55] 1.19[56]
9 TPST1 Protein-tyrosine sulfotransferase 1 [57] 1.76[58] 1.84[59] 2.09[60] 5.07[61] 4.40[62] -0.01[63]
10 GGCX Vitamin K-dependent gamma-carboxylase [64] 4.12[65] 3.81[66] 3.85[67] 5.52[68] 4.93[69] 2.27[70]
11 F8 Coagulation factor VIII [71] 0.76[72] 0.40[73] 0.57[74] 4.10[75] 3.60[76] 3.57[77]
12 GP1BA Platelet glycoprotein Ib alpha chain [78] 1.57[79] 1.30[80] 4.36[81] 5.06[82] 4.96[83] 0.92[84]
13 GP1BB Platelet glycoprotein Ib beta chain [85] [86] [87] [88] [89] [90] [91]
14 VWF von Willebrand factor [92] 4.48[93] 1.77[94] -0.75[95] 5.79[96] 2.88[97] 5.56[98]
15 GP5 Platelet glycoprotein V [99] 0.11[100] 1.27[101] -2.86[102] 0.24[103] 3.04[104] 1.27[105]
16 GP9 Platelet glycoprotein IX [106] [107] [108] [109] [110] [111] [112]
[1]
ref_hepatocyte SERPING1
Mean 849
Standard deviation 1e+03
Values 1.7 21 2.9e+02 1.9e+03 2e+03
[2]
HepG2 SERPING1
Mean 13.3
Standard deviation 11
Values 21 5.7
[3]
HepG2.C3A SERPING1
Mean 0.0248
Standard deviation 0.02
Values 0.039 0.011
[4]
HuH.7 SERPING1
Mean 7.6
Standard deviation 3.9
Values 5.6 12 5.1
[5]
SNU475 SERPING1
Mean 0.892
Standard deviation 0.73
Values 0.38 1.4
[6]
THLE SERPING1
Mean 40.8
Standard deviation 6.5
Values 45 36
[7]
liver SERPING1
Mean 1.02e+03
Standard deviation 1.1e+03
Values 2e+03 99 1.8e+03 1.1e+02
[8]
ref_hepatocyte F2
Mean 442
Standard deviation 5.2e+02
Values 40 79 98 8.2e+02 1.2e+03
[9]
HepG2 F2
Mean 204
Standard deviation 81
Values 2.6e+02 1.5e+02
[10]
HepG2.C3A F2
Mean 256
Standard deviation 95
Values 3.2e+02 1.9e+02
[11]
HuH.7 F2
Mean 321
Standard deviation 18
Values 3.1e+02 3.1e+02 3.4e+02
[12]
SNU475 F2
Mean 0.54
Standard deviation 0.16
Values 0.65 0.43
[13]
THLE F2
Mean 0.475
Standard deviation 0.27
Values 0.66 0.29
[14]
liver F2
Mean 785
Standard deviation 2.9e+02
Values 1e+03 5.3e+02 1e+03 5.3e+02
[15]
ref_hepatocyte F12
Mean 152
Standard deviation 2.1e+02
Values 1.8 1.8 22 2.7e+02 4.6e+02
[16]
HepG2 F12
Mean 2.23
Standard deviation 0.82
Values 2.8 1.6
[17]
HepG2.C3A F12
Mean 11.3
Standard deviation 4.2
Values 14 8.4
[18]
HuH.7 F12
Mean 12.8
Standard deviation 2.7
Values 10 15 13
[19]
SNU475 F12
Mean 0.0219
Standard deviation 0.0048
Values 0.019 0.025
[20]
THLE F12
Mean 0.623
Standard deviation 0.023
Values 0.64 0.61
[21]
liver F12
Mean 163
Standard deviation 1e+02
Values 2.7e+02 50 2.3e+02 1e+02
[22]
ref_hepatocyte F9
Mean 71.3
Standard deviation 94
Values 0 0.79 8.1 1.7e+02 1.8e+02
[23]
HepG2 F9
Mean 0.0179
Standard deviation 0.0071
Values 0.023 0.013
[24]
HepG2.C3A F9
Mean 0
Standard deviation 0
Values 0 0
[25]
HuH.7 F9
Mean 0.00487
Standard deviation 0.0043
Values 0.0082 0.0064 0
[26]
SNU475 F9
Mean 0
Standard deviation 0
Values 0 0
[27]
THLE F9
Mean 0
Standard deviation 0
Values 0 0
[28]
liver F9
Mean 245
Standard deviation 1.2e+02
Values 1.6e+02 3.8e+02 1.3e+02 3.1e+02
[29]
ref_hepatocyte F10
Mean 43.2
Standard deviation 44
Values 25 4.4 6.8 82 98
[30]
HepG2 F10
Mean 28.5
Standard deviation 7.1
Values 34 24
[31]
HepG2.C3A F10
Mean 49.1
Standard deviation 38
Values 76 22
[32]
HuH.7 F10
Mean 17.2
Standard deviation 3.7
Values 14 21 16
[33]
SNU475 F10
Mean 0.43
Standard deviation 0.042
Values 0.46 0.4
[34]
THLE F10
Mean 0.0869
Standard deviation 0.0026
Values 0.089 0.085
[35]
liver F10
Mean 64.8
Standard deviation 49
Values 1.3e+02 29 70 28
[36]
ref_hepatocyte KLKB1
Mean 25.1
Standard deviation 35
Values 0.73 2.3 2.2 41 79
[37]
HepG2 KLKB1
Mean 0.137
Standard deviation 0.048
Values 0.1 0.17
[38]
HepG2.C3A KLKB1
Mean 0.913
Standard deviation 0.0015
Values 0.91 0.91
[39]
HuH.7 KLKB1
Mean 0.434
Standard deviation 0.48
Values 0.11 0.98 0.21
[40]
SNU475 KLKB1
Mean 0.00992
Standard deviation 0.0075
Values 0.0046 0.015
[41]
THLE KLKB1
Mean 0.0287
Standard deviation 0.018
Values 0.041 0.016
[42]
liver KLKB1
Mean 44.5
Standard deviation 24
Values 80 28 37 33
[43]
ref_hepatocyte TPST2
Mean 23.9
Standard deviation 15
Values 10 20 12 46 31
[44]
HepG2 TPST2
Mean 9.86
Standard deviation 0.75
Values 10 9.3
[45]
HepG2.C3A TPST2
Mean 9.33
Standard deviation 2.1
Values 11 7.9
[46]
HuH.7 TPST2
Mean 13.5
Standard deviation 8.4
Values 8.1 23 9.3
[47]
SNU475 TPST2
Mean 17.4
Standard deviation 0.3
Values 18 17
[48]
THLE TPST2
Mean 5.73
Standard deviation 0.43
Values 5.4 6
[49]
liver TPST2
Mean 48.3
Standard deviation 14
Values 70 40 42 42
[50]
ref_hepatocyte F11
Mean 20.4
Standard deviation 18
Values 25 1.9 1.7 30 44
[51]
HepG2 F11
Mean 7.11
Standard deviation 4.7
Values 3.8 10
[52]
HepG2.C3A F11
Mean 31.5
Standard deviation 4.6
Values 28 35
[53]
HuH.7 F11
Mean 1.76
Standard deviation 1.5
Values 0.93 3.4 0.91
[54]
SNU475 F11
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[55]
THLE F11
Mean 0.00592
Standard deviation 0.0084
Values 0.012 0
[56]
liver F11
Mean 73
Standard deviation 13
Values 67 91 72 62
[57]
ref_hepatocyte TPST1
Mean 14.3
Standard deviation 9.2
Values 7.6 9.4 6.7 27 20
[58]
HepG2 TPST1
Mean 9.42
Standard deviation 1.2
Values 8.6 10
[59]
HepG2.C3A TPST1
Mean 12.9
Standard deviation 3
Values 15 11
[60]
HuH.7 TPST1
Mean 16.3
Standard deviation 2.2
Values 14 18 17
[61]
SNU475 TPST1
Mean 17.7
Standard deviation 2.8
Values 16 20
[62]
THLE TPST1
Mean 15.6
Standard deviation 0.81
Values 15 16
[63]
liver TPST1
Mean 22.4
Standard deviation 3.1
Values 22 21 27 20
[64]
ref_hepatocyte GGCX
Mean 13.4
Standard deviation 7.6
Values 12 7.9 4.6 19 23
[65]
HepG2 GGCX
Mean 45.2
Standard deviation 8
Values 39 51
[66]
HepG2.C3A GGCX
Mean 47.5
Standard deviation 0.71
Values 47 48
[67]
HuH.7 GGCX
Mean 51.7
Standard deviation 6.2
Values 57 45 53
[68]
SNU475 GGCX
Mean 22.5
Standard deviation 1.7
Values 21 24
[69]
THLE GGCX
Mean 21.2
Standard deviation 4
Values 18 24
[70]
liver GGCX
Mean 102
Standard deviation 24
Values 78 1.1e+02 88 1.3e+02
[71]
ref_hepatocyte F8
Mean 1.68
Standard deviation 1.5
Values 0.18 0.85 0.94 3.6 2.8
[72]
HepG2 F8
Mean 0.551
Standard deviation 0.063
Values 0.6 0.51
[73]
HepG2.C3A F8
Mean 0.558
Standard deviation 0.077
Values 0.61 0.5
[74]
HuH.7 F8
Mean 0.668
Standard deviation 0.14
Values 0.71 0.78 0.52
[75]
SNU475 F8
Mean 1.06
Standard deviation 0.33
Values 1.3 0.83
[76]
THLE F8
Mean 1.05
Standard deviation 0.19
Values 1.2 0.91
[77]
liver F8
Mean 31.4
Standard deviation 10
Values 27 46 22 30
[78]
ref_hepatocyte GP1BA
Mean 0.18
Standard deviation 0.32
Values 0 0 0.75 0 0.15
[79]
HepG2 GP1BA
Mean 0.104
Standard deviation 0.032
Values 0.13 0.082
[80]
HepG2.C3A GP1BA
Mean 0.112
Standard deviation 0.0078
Values 0.11 0.12
[81]
HuH.7 GP1BA
Mean 0.99
Standard deviation 0.51
Values 1 1.5 0.46
[82]
SNU475 GP1BA
Mean 0.222
Standard deviation 0.17
Values 0.34 0.1
[83]
THLE GP1BA
Mean 0.291
Standard deviation 0.018
Values 0.28 0.3
[84]
liver GP1BA
Mean 0.538
Standard deviation 0.38
Values 0.24 0.47 0.36 1.1
[85]
ref_hepatocyte GP1BB
Mean 0.139
Standard deviation 0.19
Values 0 0.12 0.11 0.46 0
[86]
HepG2 GP1BB
Missing
[87]
HepG2.C3A GP1BB
Missing
[88]
HuH.7 GP1BB
Missing
[89]
SNU475 GP1BB
Missing
[90]
THLE GP1BB
Missing
[91]
liver GP1BB
Missing
[92]
ref_hepatocyte VWF
Mean 0.138
Standard deviation 0.13
Values 0.14 0.026 0 0.32 0.2
[93]
HepG2 VWF
Mean 0.599
Standard deviation 0.15
Values 0.7 0.49
[94]
HepG2.C3A VWF
Mean 0.12
Standard deviation 0.078
Values 0.17 0.064
[95]
HuH.7 VWF
Mean 0.022
Standard deviation 0.031
Values 0.0082 0.058 0
[96]
SNU475 VWF
Mean 0.283
Standard deviation 0.027
Values 0.3 0.26
[97]
THLE VWF
Mean 0.0529
Standard deviation 0.0079
Values 0.047 0.059
[98]
liver VWF
Mean 10.3
Standard deviation 3.3
Values 8.3 10 7.8 15
[99]
ref_hepatocyte GP5
Mean 0.0581
Standard deviation 0.064
Values 0 0.1 0 0.043 0.15
[100]
HepG2 GP5
Mean 0.0122
Standard deviation 0.001
Values 0.011 0.013
[101]
HepG2.C3A GP5
Mean 0.0355
Standard deviation 0.0047
Values 0.039 0.032
[102]
HuH.7 GP5
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[103]
SNU475 GP5
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[104]
THLE GP5
Mean 0.0248
Standard deviation 0.01
Values 0.018 0.032
[105]
liver GP5
Mean 0.22
Standard deviation 0.043
Values 0.26 0.26 0.18 0.19
[106]
ref_hepatocyte GP9
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[107]
HepG2 GP9
Mean 0
Standard deviation 0
Values 0 0
[108]
HepG2.C3A GP9
Mean 0
Standard deviation 0
Values 0 0
[109]
HuH.7 GP9
Mean 0
Standard deviation 0
Values 0 0 0
[110]
SNU475 GP9
Mean 0
Standard deviation 0
Values 0 0
[111]
THLE GP9
Mean 0
Standard deviation 0
Values 0 0
[112]
liver GP9
Mean 0.0284
Standard deviation 0.034
Values 0.024 0 0.077 0.013