REACTOME_DEFECTIVE_RIPK1_MEDIATED_REGULATED_NECROSIS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 FADD FAS-associated death domain protein [1] -0.02[2] -0.77[3] 0.25[4] 1.04[5] 0.02[6] -1.35[7]
2 CASP8 Caspase-8 [8] -0.04[9] 0.49[10] -0.04[11] -0.97[12] -0.55[13] -0.99[14]
3 TRADD Tumor necrosis factor receptor type 1-associated DEATH domain protein -0.31[15] -0.52[16] -1.39[17] -1.87[18] -0.86[19] -0.16[20]
4 TRAF2 TNF receptor-associated factor 2 [21] 0.17[22] 0.19[23] 0.22[24] -0.77[25] 0.40[26] -0.37[27]
5 RIPK1 Receptor-interacting serine/threonine-protein kinase 1 [28] 0.23[29] 0.35[30] 0.33[31] 0.19[32] 0.87[33] 1.91[34]
[1]
ref_hepatocyte FADD
Mean 9.28
Standard deviation 6.6
Values 3.8 12 20 6.3 5.1
[2]
HepG2 FADD
Mean 21.1
Standard deviation 4.6
Values 24 18
[3]
HepG2.C3A FADD
Mean 11.5
Standard deviation 1.6
Values 10 13
[4]
HuH.7 FADD
Mean 18.2
Standard deviation 3.2
Values 16 16 22
[5]
SNU475 FADD
Mean 65.1
Standard deviation 11
Values 73 58
[6]
THLE FADD
Mean 16
Standard deviation 3.5
Values 14 19
[7]
liver FADD
Mean 3.86
Standard deviation 1.3
Values 2.5 4.9 3 5.1
[8]
ref_hepatocyte CASP8
Mean 8.88
Standard deviation 6.8
Values 18 13 8.9 1.9 2.8
[9]
HepG2 CASP8
Mean 19.9
Standard deviation 3.1
Values 22 18
[10]
HepG2.C3A CASP8
Mean 26.3
Standard deviation 13
Values 17 35
[11]
HuH.7 CASP8
Mean 14.2
Standard deviation 3.6
Values 14 11 18
[12]
SNU475 CASP8
Mean 15.4
Standard deviation 0.7
Values 16 15
[13]
THLE CASP8
Mean 10.3
Standard deviation 0.97
Values 9.6 11
[14]
liver CASP8
Mean 4.72
Standard deviation 0.87
Values 3.4 5.2 5.3 5
[15]
ref_hepatocyte TRADD
Mean 5.53
Standard deviation 1.5
Values 3.6 4.8 5.3 7.4 6.5
[16]
HepG2 TRADD
Mean 10.2
Standard deviation 3.2
Values 12 8
[17]
HepG2.C3A TRADD
Mean 8.12
Standard deviation 2.3
Values 9.8 6.5
[18]
HuH.7 TRADD
Mean 3.47
Standard deviation 1.2
Values 2.9 2.7 4.9
[19]
SNU475 TRADD
Mean 5.13
Standard deviation 1
Values 5.8 4.4
[20]
THLE TRADD
Mean 5.18
Standard deviation 0.33
Values 4.9 5.4
[21]
liver TRADD
Mean 5.22
Standard deviation 3
Values 9.2 2.7 6 3
[22]
ref_hepatocyte TRAF2
Mean 5.07
Standard deviation 4.4
Values 1.1 5.1 12 4.2 2.5
[23]
HepG2 TRAF2
Mean 13.1
Standard deviation 2.2
Values 15 12
[24]
HepG2.C3A TRAF2
Mean 12.2
Standard deviation 1.2
Values 13 11
[25]
HuH.7 TRAF2
Mean 9.75
Standard deviation 2.3
Values 9.4 7.6 12
[26]
SNU475 TRAF2
Mean 10.1
Standard deviation 0.75
Values 9.6 11
[27]
THLE TRAF2
Mean 11.4
Standard deviation 2.7
Values 9.5 13
[28]
liver TRAF2
Mean 4.15
Standard deviation 1.4
Values 4 2.6 6 4.1
[29]
ref_hepatocyte RIPK1
Mean 4.28
Standard deviation 0.89
Values 3.7 4.4 3.1 5.4 4.8
[30]
HepG2 RIPK1
Mean 11.5
Standard deviation 4
Values 8.7 14
[31]
HepG2.C3A RIPK1
Mean 11.5
Standard deviation 0.53
Values 11 12
[32]
HuH.7 RIPK1
Mean 8.85
Standard deviation 0.42
Values 8.4 9.3 8.8
[33]
SNU475 RIPK1
Mean 16.6
Standard deviation 2.9
Values 19 15
[34]
THLE RIPK1
Mean 13.4
Standard deviation 1
Values 13 14
[35]
liver RIPK1
Mean 17
Standard deviation 5.1
Values 12 21 13 22