REACTOME_DEFECTIVE_FACTOR_IX_CAUSES_HEMOPHILIA_B Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 F9 Coagulation factor IX [1] -11.08[2] [3] -12.78[4] [5] [6] 0.00[7]
2 F10 Coagulation factor X [8] 0.28[9] 0.41[10] -0.27[11] -4.02[12] -6.23[13] -1.20[14]
3 F11 Coagulation factor XI [15] -0.63[16] 0.85[17] -2.48[18] -10.47[19] -9.02[20] 0.06[21]
4 GGCX Vitamin K-dependent gamma-carboxylase [22] 2.64[23] 2.05[24] 3.01[25] 3.39[26] 3.40[27] 1.15[28]
5 F8 Coagulation factor VIII [29] -0.72[30] -1.36[31] -0.27[32] 1.97[33] 2.06[34] 2.45[35]
6 GP1BA Platelet glycoprotein Ib alpha chain [36] 0.09[37] -0.46[38] 3.51[39] 2.93[40] 3.42[41] -0.20[42]
7 GP1BB Platelet glycoprotein Ib beta chain [43] [44] [45] [46] [47] [48] [49]
8 GP5 Platelet glycoprotein V [50] -1.37[51] -0.49[52] -3.71[53] -1.89[54] 1.50[55] 0.14[56]
9 GP9 Platelet glycoprotein IX [57] [58] [59] [60] [61] [62] [63]
[1]
ref_hepatocyte F9
Mean 71.3
Standard deviation 94
Values 0 0.79 8.1 1.7e+02 1.8e+02
[2]
HepG2 F9
Mean 0.0179
Standard deviation 0.0071
Values 0.023 0.013
[3]
HepG2.C3A F9
Mean 0
Standard deviation 0
Values 0 0
[4]
HuH.7 F9
Mean 0.00487
Standard deviation 0.0043
Values 0.0082 0.0064 0
[5]
SNU475 F9
Mean 0
Standard deviation 0
Values 0 0
[6]
THLE F9
Mean 0
Standard deviation 0
Values 0 0
[7]
liver F9
Mean 245
Standard deviation 1.2e+02
Values 1.6e+02 3.8e+02 1.3e+02 3.1e+02
[8]
ref_hepatocyte F10
Mean 43.2
Standard deviation 44
Values 25 4.4 6.8 82 98
[9]
HepG2 F10
Mean 28.5
Standard deviation 7.1
Values 34 24
[10]
HepG2.C3A F10
Mean 49.1
Standard deviation 38
Values 76 22
[11]
HuH.7 F10
Mean 17.2
Standard deviation 3.7
Values 14 21 16
[12]
SNU475 F10
Mean 0.43
Standard deviation 0.042
Values 0.46 0.4
[13]
THLE F10
Mean 0.0869
Standard deviation 0.0026
Values 0.089 0.085
[14]
liver F10
Mean 64.8
Standard deviation 49
Values 1.3e+02 29 70 28
[15]
ref_hepatocyte F11
Mean 20.4
Standard deviation 18
Values 25 1.9 1.7 30 44
[16]
HepG2 F11
Mean 7.11
Standard deviation 4.7
Values 3.8 10
[17]
HepG2.C3A F11
Mean 31.5
Standard deviation 4.6
Values 28 35
[18]
HuH.7 F11
Mean 1.76
Standard deviation 1.5
Values 0.93 3.4 0.91
[19]
SNU475 F11
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[20]
THLE F11
Mean 0.00592
Standard deviation 0.0084
Values 0.012 0
[21]
liver F11
Mean 73
Standard deviation 13
Values 67 91 72 62
[22]
ref_hepatocyte GGCX
Mean 13.4
Standard deviation 7.6
Values 12 7.9 4.6 19 23
[23]
HepG2 GGCX
Mean 45.2
Standard deviation 8
Values 39 51
[24]
HepG2.C3A GGCX
Mean 47.5
Standard deviation 0.71
Values 47 48
[25]
HuH.7 GGCX
Mean 51.7
Standard deviation 6.2
Values 57 45 53
[26]
SNU475 GGCX
Mean 22.5
Standard deviation 1.7
Values 21 24
[27]
THLE GGCX
Mean 21.2
Standard deviation 4
Values 18 24
[28]
liver GGCX
Mean 102
Standard deviation 24
Values 78 1.1e+02 88 1.3e+02
[29]
ref_hepatocyte F8
Mean 1.68
Standard deviation 1.5
Values 0.18 0.85 0.94 3.6 2.8
[30]
HepG2 F8
Mean 0.551
Standard deviation 0.063
Values 0.6 0.51
[31]
HepG2.C3A F8
Mean 0.558
Standard deviation 0.077
Values 0.61 0.5
[32]
HuH.7 F8
Mean 0.668
Standard deviation 0.14
Values 0.71 0.78 0.52
[33]
SNU475 F8
Mean 1.06
Standard deviation 0.33
Values 1.3 0.83
[34]
THLE F8
Mean 1.05
Standard deviation 0.19
Values 1.2 0.91
[35]
liver F8
Mean 31.4
Standard deviation 10
Values 27 46 22 30
[36]
ref_hepatocyte GP1BA
Mean 0.18
Standard deviation 0.32
Values 0 0 0.75 0 0.15
[37]
HepG2 GP1BA
Mean 0.104
Standard deviation 0.032
Values 0.13 0.082
[38]
HepG2.C3A GP1BA
Mean 0.112
Standard deviation 0.0078
Values 0.11 0.12
[39]
HuH.7 GP1BA
Mean 0.99
Standard deviation 0.51
Values 1 1.5 0.46
[40]
SNU475 GP1BA
Mean 0.222
Standard deviation 0.17
Values 0.34 0.1
[41]
THLE GP1BA
Mean 0.291
Standard deviation 0.018
Values 0.28 0.3
[42]
liver GP1BA
Mean 0.538
Standard deviation 0.38
Values 0.24 0.47 0.36 1.1
[43]
ref_hepatocyte GP1BB
Mean 0.139
Standard deviation 0.19
Values 0 0.12 0.11 0.46 0
[44]
HepG2 GP1BB
Missing
[45]
HepG2.C3A GP1BB
Missing
[46]
HuH.7 GP1BB
Missing
[47]
SNU475 GP1BB
Missing
[48]
THLE GP1BB
Missing
[49]
liver GP1BB
Missing
[50]
ref_hepatocyte GP5
Mean 0.0581
Standard deviation 0.064
Values 0 0.1 0 0.043 0.15
[51]
HepG2 GP5
Mean 0.0122
Standard deviation 0.001
Values 0.011 0.013
[52]
HepG2.C3A GP5
Mean 0.0355
Standard deviation 0.0047
Values 0.039 0.032
[53]
HuH.7 GP5
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[54]
SNU475 GP5
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[55]
THLE GP5
Mean 0.0248
Standard deviation 0.01
Values 0.018 0.032
[56]
liver GP5
Mean 0.22
Standard deviation 0.043
Values 0.26 0.26 0.18 0.19
[57]
ref_hepatocyte GP9
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[58]
HepG2 GP9
Mean 0
Standard deviation 0
Values 0 0
[59]
HepG2.C3A GP9
Mean 0
Standard deviation 0
Values 0 0
[60]
HuH.7 GP9
Mean 0
Standard deviation 0
Values 0 0 0
[61]
SNU475 GP9
Mean 0
Standard deviation 0
Values 0 0
[62]
THLE GP9
Mean 0
Standard deviation 0
Values 0 0
[63]
liver GP9
Mean 0.0284
Standard deviation 0.034
Values 0.024 0 0.077 0.013