REACTOME_DEFECTIVE_EXT2_CAUSES_EXOSTOSES_2 Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GPC3 Glypican-3 [1] 0.75[2] 1.07[3] 0.64[4] -7.62[5] -6.86[6] -8.34[7]
2 SDC1 Syndecan-1 [8] -1.92[9] -2.49[10] -1.21[11] -2.08[12] -3.83[13] 0.68[14]
3 SDC4 Syndecan-4 [15] -1.12[16] -1.55[17] -1.85[18] -1.47[19] 0.63[20] -0.21[21]
4 SDC2 Syndecan-2 [22] -1.02[23] -0.18[24] 0.39[25] 0.09[26] -2.57[27] 0.52[28]
5 EXT1 Exostosin-1 [29] -2.43[30] -2.96[31] -1.08[32] 0.40[33] 0.35[34] -0.09[35]
6 GPC1 Glypican-1 [36] -0.93[37] -4.37[38] -7.45[39] 2.73[40] 2.07[41] -0.63[42]
7 EXT2 Exostosin-2 [43] 0.02[44] -1.21[45] -1.22[46] -0.14[47] 1.89[48] 0.73[49]
8 AGRN Agrin [50] 2.73[51] 2.05[52] 2.47[53] 3.81[54] 3.41[55] 0.97[56]
9 GPC6 Glypican-6 [57] 1.18[58] 0.25[59] 1.77[60] 4.22[61] 2.86[62] 3.15[63]
10 SDC3 Syndecan-3 [64] 1.37[65] -4.97[66] -0.02[67] 3.40[68] 4.24[69] 2.65[70]
11 HSPG2 Basement membrane-specific heparan sulfate proteoglycan core protein 6.19[71] 4.32[72] 5.64[73] 6.32[74] 7.04[75] 6.27[76]
12 GPC4 Glypican-4 [77] -2.44[78] -6.60[79] -1.90[80] 5.76[81] -1.46[82] 0.84[83]
13 GPC5 Glypican-5 [84] -4.62[85] -6.04[86] -0.73[87] -2.96[88] -1.90[89] 3.47[90]
14 GPC2 Glypican-2 [91] 1.48[92] 0.81[93] 3.76[94] 3.62[95] 3.01[96] -3.17[97]
[1]
ref_hepatocyte GPC3
Mean 126
Standard deviation 2.8e+02
Values 6.3e+02 0.054 0.022 0.2 0.45
[2]
HepG2 GPC3
Mean 1.26e+03
Standard deviation 9.2
Values 1.3e+03 1.3e+03
[3]
HepG2.C3A GPC3
Mean 1.5e+03
Standard deviation 6.5e+02
Values 2e+03 1e+03
[4]
HuH.7 GPC3
Mean 561
Standard deviation 1.5e+02
Values 4.3e+02 7.2e+02 5.4e+02
[5]
SNU475 GPC3
Mean 0.967
Standard deviation 0.21
Values 1.1 0.82
[6]
THLE GPC3
Mean 1.25
Standard deviation 0.31
Values 1.5 1
[7]
liver GPC3
Mean 0.594
Standard deviation 0.31
Values 0.47 0.46 1.1 0.4
[8]
ref_hepatocyte SDC1
Mean 90.9
Standard deviation 70
Values 30 69 33 1.3e+02 1.9e+02
[9]
HepG2 SDC1
Mean 143
Standard deviation 14
Values 1.5e+02 1.3e+02
[10]
HepG2.C3A SDC1
Mean 92.1
Standard deviation 9.8
Values 85 99
[11]
HuH.7 SDC1
Mean 113
Standard deviation 31
Values 1.3e+02 77 1.3e+02
[12]
SNU475 SDC1
Mean 32.6
Standard deviation 5
Values 36 29
[13]
THLE SDC1
Mean 7.4
Standard deviation 0.31
Values 7.6 7.2
[14]
liver SDC1
Mean 222
Standard deviation 69
Values 1.8e+02 2.1e+02 3.2e+02 1.7e+02
[15]
ref_hepatocyte SDC4
Mean 75.2
Standard deviation 11
Values 84 85 60 78 68
[16]
HepG2 SDC4
Mean 206
Standard deviation 1.1e+02
Values 2.8e+02 1.3e+02
[17]
HepG2.C3A SDC4
Mean 146
Standard deviation 40
Values 1.7e+02 1.2e+02
[18]
HuH.7 SDC4
Mean 59.9
Standard deviation 26
Values 47 90 43
[19]
SNU475 SDC4
Mean 41
Standard deviation 1.5
Values 42 40
[20]
THLE SDC4
Mean 134
Standard deviation 15
Values 1.2e+02 1.4e+02
[21]
liver SDC4
Mean 99.2
Standard deviation 32
Values 1.1e+02 74 1.4e+02 74
[22]
ref_hepatocyte SDC2
Mean 42.2
Standard deviation 32
Values 57 12 12 42 87
[23]
HepG2 SDC2
Mean 124
Standard deviation 1.5
Values 1.2e+02 1.3e+02
[24]
HepG2.C3A SDC2
Mean 212
Standard deviation 41
Values 2.4e+02 1.8e+02
[25]
HuH.7 SDC2
Mean 158
Standard deviation 56
Values 1.2e+02 2.2e+02 1.3e+02
[26]
SNU475 SDC2
Mean 68
Standard deviation 21
Values 83 53
[27]
THLE SDC2
Mean 8.21
Standard deviation 1.9
Values 9.6 6.9
[28]
liver SDC2
Mean 92.5
Standard deviation 51
Values 1.7e+02 61 82 60
[29]
ref_hepatocyte EXT1
Mean 17.9
Standard deviation 9.9
Values 4.3 18 17 32 18
[30]
HepG2 EXT1
Mean 19.8
Standard deviation 0.59
Values 20 19
[31]
HepG2.C3A EXT1
Mean 13.1
Standard deviation 1.6
Values 14 12
[32]
HuH.7 EXT1
Mean 24.3
Standard deviation 6.8
Values 22 32 19
[33]
SNU475 EXT1
Mean 35.7
Standard deviation 2
Values 37 34
[34]
THLE EXT1
Mean 26.3
Standard deviation 6.9
Values 21 31
[35]
liver EXT1
Mean 25.6
Standard deviation 13
Values 15 38 13 36
[36]
ref_hepatocyte GPC1
Mean 11.5
Standard deviation 7.6
Values 1.4 21 16 9.6 8.7
[37]
HepG2 GPC1
Mean 35.9
Standard deviation 11
Values 44 28
[38]
HepG2.C3A GPC1
Mean 3.16
Standard deviation 0.57
Values 2.8 3.6
[39]
HuH.7 GPC1
Mean 0.188
Standard deviation 0.13
Values 0.3 0.23 0.037
[40]
SNU475 GPC1
Mean 115
Standard deviation 39
Values 1.4e+02 88
[41]
THLE GPC1
Mean 55.5
Standard deviation 8.3
Values 50 61
[42]
liver GPC1
Mean 11.3
Standard deviation 3.4
Values 7.6 13 15 9.6
[43]
ref_hepatocyte EXT2
Mean 9.13
Standard deviation 1.8
Values 9.9 9 7.3 12 7.6
[44]
HepG2 EXT2
Mean 55.3
Standard deviation 3.9
Values 58 53
[45]
HepG2.C3A EXT2
Mean 22.5
Standard deviation 0.32
Values 22 23
[46]
HuH.7 EXT2
Mean 11.3
Standard deviation 2.6
Values 10 14 9.5
[47]
SNU475 EXT2
Mean 12.5
Standard deviation 0.084
Values 12 13
[48]
THLE EXT2
Mean 39.2
Standard deviation 9
Values 33 46
[49]
liver EXT2
Mean 23.1
Standard deviation 7.4
Values 13 28 30 22
[50]
ref_hepatocyte AGRN
Mean 5.08
Standard deviation 2.6
Values 4.9 9.5 3.2 4.4 3.4
[51]
HepG2 AGRN
Mean 201
Standard deviation 74
Values 2.5e+02 1.5e+02
[52]
HepG2.C3A AGRN
Mean 120
Standard deviation 34
Values 1.4e+02 95
[53]
HuH.7 AGRN
Mean 80.8
Standard deviation 15
Values 96 66 80
[54]
SNU475 AGRN
Mean 108
Standard deviation 64
Values 1.5e+02 63
[55]
THLE AGRN
Mean 62.4
Standard deviation 19
Values 49 76
[56]
liver AGRN
Mean 15.2
Standard deviation 13
Values 4 26 3.2 28
[57]
ref_hepatocyte GPC6
Mean 2.38
Standard deviation 1.5
Values 3.3 1.3 0.41 2.8 4
[58]
HepG2 GPC6
Mean 32
Standard deviation 10
Values 25 39
[59]
HepG2.C3A GPC6
Mean 16.1
Standard deviation 1.8
Values 15 17
[60]
HuH.7 GPC6
Mean 23.3
Standard deviation 7.4
Values 21 31 17
[61]
SNU475 GPC6
Mean 67.1
Standard deviation 28
Values 87 47
[62]
THLE GPC6
Mean 19.9
Standard deviation 5
Values 16 23
[63]
liver GPC6
Mean 32.3
Standard deviation 8.7
Values 38 30 21 40
[64]
ref_hepatocyte SDC3
Mean 1.04
Standard deviation 0.71
Values 0.11 0.84 0.73 1.7 1.8
[65]
HepG2 SDC3
Mean 16
Standard deviation 2.6
Values 18 14
[66]
HepG2.C3A SDC3
Mean 0.19
Standard deviation 0.035
Values 0.17 0.21
[67]
HuH.7 SDC3
Mean 2.95
Standard deviation 1.2
Values 4 1.7 3.2
[68]
SNU475 SDC3
Mean 16.7
Standard deviation 0.42
Values 17 16
[69]
THLE SDC3
Mean 22.7
Standard deviation 0.49
Values 22 23
[70]
liver SDC3
Mean 9.95
Standard deviation 2.5
Values 9.5 13 7.1 10
[71]
ref_hepatocyte HSPG2
Mean 0.417
Standard deviation 0.41
Values 1.1 0.16 0.49 0.16 0.18
[72]
HepG2 HSPG2
Mean 181
Standard deviation 62
Values 2.3e+02 1.4e+02
[73]
HepG2.C3A HSPG2
Mean 47.5
Standard deviation 2.4
Values 46 49
[74]
HuH.7 HSPG2
Mean 59.8
Standard deviation 39
Values 1e+02 34 40
[75]
SNU475 HSPG2
Mean 50.5
Standard deviation 35
Values 75 26
[76]
THLE HSPG2
Mean 63.4
Standard deviation 18
Values 50 76
[77]
liver HSPG2
Mean 49
Standard deviation 38
Values 14 64 22 96
[78]
ref_hepatocyte GPC4
Mean 0.349
Standard deviation 0.51
Values 0.13 0.065 1.2 0 0.33
[79]
HepG2 GPC4
Mean 0.383
Standard deviation 0.074
Values 0.44 0.33
[80]
HepG2.C3A GPC4
Mean 0.0204
Standard deviation 0.0014
Values 0.019 0.021
[81]
HuH.7 GPC4
Mean 0.269
Standard deviation 0.25
Values 0.18 0.55 0.075
[82]
SNU475 GPC4
Mean 28.5
Standard deviation 18
Values 41 16
[83]
THLE GPC4
Mean 0.147
Standard deviation 0.048
Values 0.11 0.18
[84]
liver GPC4
Mean 0.949
Standard deviation 0.44
Values 0.71 1.1 0.51 1.5
[85]
ref_hepatocyte GPC5
Mean 0.0619
Standard deviation 0.066
Values 0 0 0.14 0.052 0.11
[86]
HepG2 GPC5
Mean 0.015
Standard deviation 0.0031
Values 0.017 0.013
[87]
HepG2.C3A GPC5
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[88]
HuH.7 GPC5
Mean 0.107
Standard deviation 0.094
Values 0.082 0.21 0.028
[89]
SNU475 GPC5
Mean 0.012
Standard deviation 0.0027
Values 0.014 0.01
[90]
THLE GPC5
Mean 0.0192
Standard deviation 0.01
Values 0.012 0.027
[91]
liver GPC5
Mean 1.04
Standard deviation 0.64
Values 2 0.83 0.72 0.64
[92]
ref_hepatocyte GPC2
Mean 0.0542
Standard deviation 0.044
Values 0.094 0 0.019 0.06 0.098
[93]
HepG2 GPC2
Mean 0.9
Standard deviation 0.41
Values 1.2 0.61
[94]
HepG2.C3A GPC2
Mean 0.541
Standard deviation 0.0087
Values 0.53 0.55
[95]
HuH.7 GPC2
Mean 2.11
Standard deviation 0.72
Values 2.1 1.4 2.8
[96]
SNU475 GPC2
Mean 1.01
Standard deviation 0.087
Values 0.95 1.1
[97]
THLE GPC2
Mean 0.506
Standard deviation 0.038
Values 0.53 0.48
[98]
liver GPC2
Mean 0.00918
Standard deviation 0.011
Values 0.024 0 0 0.013