REACTOME_DEFECTIVE_B4GALT7_CAUSES_EDS_PROGEROID_TYPE Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 GPC3 Glypican-3 [1] 0.71[2] 1.02[3] 0.58[4] -7.62[5] -7.16[6] -8.53[7]
2 SDC1 Syndecan-1 [8] -1.97[9] -2.54[10] -1.27[11] -2.08[12] -4.12[13] 0.48[14]
3 SDC4 Syndecan-4 [15] -1.17[16] -1.60[17] -1.90[18] -1.47[19] 0.33[20] -0.41[21]
4 SDC2 Syndecan-2 [22] -1.06[23] -0.23[24] 0.33[25] 0.09[26] -2.86[27] 0.33[28]
5 GPC1 Glypican-1 [29] -0.97[30] -4.42[31] -7.51[32] 2.73[33] 1.77[34] -0.83[35]
6 B4GALT7 Beta-1,4-galactosyltransferase 7 [36] -2.00[37] -1.96[38] -0.69[39] -0.80[40] -0.37[41] -1.29[42]
7 AGRN Agrin [43] 2.68[44] 2.00[45] 2.41[46] 3.81[47] 3.12[48] 0.77[49]
8 GPC6 Glypican-6 [50] 1.13[51] 0.20[52] 1.72[53] 4.22[54] 2.56[55] 2.96[56]
9 SDC3 Syndecan-3 [57] 1.33[58] -5.02[59] -0.08[60] 3.40[61] 3.94[62] 2.45[63]
10 DCN Decorin [64] -7.82[65] -9.66[66] -5.85[67] 1.82[68] 6.24[69] 5.40[70]
11 BGN Biglycan [71] 0.49[72] -4.86[73] -6.19[74] 2.06[75] -0.21[76] 5.05[77]
12 HSPG2 Basement membrane-specific heparan sulfate proteoglycan core protein 6.14[78] 4.27[79] 5.59[80] 6.32[81] 6.75[82] 6.07[83]
13 VCAN Versican core protein [84] 3.26[85] -2.01[86] 3.04[87] 1.77[88] 6.32[89] 3.53[90]
14 GPC4 Glypican-4 [91] -2.48[92] -6.65[93] -1.95[94] 5.76[95] -1.75[96] 0.64[97]
15 CSPG5 Chondroitin sulfate proteoglycan 5 [98] -2.69[99] -5.53[100] 1.27[101] 1.43[102] -0.43[103] -2.53[104]
16 GPC5 Glypican-5 [105] -4.66[106] -6.09[107] -0.78[108] -2.96[109] -2.19[110] 3.27[111]
17 GPC2 Glypican-2 [112] 1.43[113] 0.76[114] 3.71[115] 3.62[116] 2.72[117] -3.37[118]
18 NCAN Neurocan core protein [119] 0.23[120] -2.67[121] 0.59[122] -3.28[123] -0.16[124] -1.13[125]
19 CSPG4 Chondroitin sulfate proteoglycan 4 [126] 2.06[127] 0.96[128] 3.69[129] 7.44[130] 8.36[131] 5.50[132]
20 BCAN Brevican core protein [133] 6.73[134] 6.80[135] 5.96[136] 7.63[137] 5.84[138] 2.41[139]
[1]
ref_hepatocyte GPC3
Mean 126
Standard deviation 2.8e+02
Values 6.3e+02 0.054 0.022 0.2 0.45
[2]
HepG2 GPC3
Mean 1.26e+03
Standard deviation 9.2
Values 1.3e+03 1.3e+03
[3]
HepG2.C3A GPC3
Mean 1.5e+03
Standard deviation 6.5e+02
Values 2e+03 1e+03
[4]
HuH.7 GPC3
Mean 561
Standard deviation 1.5e+02
Values 4.3e+02 7.2e+02 5.4e+02
[5]
SNU475 GPC3
Mean 0.967
Standard deviation 0.21
Values 1.1 0.82
[6]
THLE GPC3
Mean 1.25
Standard deviation 0.31
Values 1.5 1
[7]
liver GPC3
Mean 0.594
Standard deviation 0.31
Values 0.47 0.46 1.1 0.4
[8]
ref_hepatocyte SDC1
Mean 90.9
Standard deviation 70
Values 30 69 33 1.3e+02 1.9e+02
[9]
HepG2 SDC1
Mean 143
Standard deviation 14
Values 1.5e+02 1.3e+02
[10]
HepG2.C3A SDC1
Mean 92.1
Standard deviation 9.8
Values 85 99
[11]
HuH.7 SDC1
Mean 113
Standard deviation 31
Values 1.3e+02 77 1.3e+02
[12]
SNU475 SDC1
Mean 32.6
Standard deviation 5
Values 36 29
[13]
THLE SDC1
Mean 7.4
Standard deviation 0.31
Values 7.6 7.2
[14]
liver SDC1
Mean 222
Standard deviation 69
Values 1.8e+02 2.1e+02 3.2e+02 1.7e+02
[15]
ref_hepatocyte SDC4
Mean 75.2
Standard deviation 11
Values 84 85 60 78 68
[16]
HepG2 SDC4
Mean 206
Standard deviation 1.1e+02
Values 2.8e+02 1.3e+02
[17]
HepG2.C3A SDC4
Mean 146
Standard deviation 40
Values 1.7e+02 1.2e+02
[18]
HuH.7 SDC4
Mean 59.9
Standard deviation 26
Values 47 90 43
[19]
SNU475 SDC4
Mean 41
Standard deviation 1.5
Values 42 40
[20]
THLE SDC4
Mean 134
Standard deviation 15
Values 1.2e+02 1.4e+02
[21]
liver SDC4
Mean 99.2
Standard deviation 32
Values 1.1e+02 74 1.4e+02 74
[22]
ref_hepatocyte SDC2
Mean 42.2
Standard deviation 32
Values 57 12 12 42 87
[23]
HepG2 SDC2
Mean 124
Standard deviation 1.5
Values 1.2e+02 1.3e+02
[24]
HepG2.C3A SDC2
Mean 212
Standard deviation 41
Values 2.4e+02 1.8e+02
[25]
HuH.7 SDC2
Mean 158
Standard deviation 56
Values 1.2e+02 2.2e+02 1.3e+02
[26]
SNU475 SDC2
Mean 68
Standard deviation 21
Values 83 53
[27]
THLE SDC2
Mean 8.21
Standard deviation 1.9
Values 9.6 6.9
[28]
liver SDC2
Mean 92.5
Standard deviation 51
Values 1.7e+02 61 82 60
[29]
ref_hepatocyte GPC1
Mean 11.5
Standard deviation 7.6
Values 1.4 21 16 9.6 8.7
[30]
HepG2 GPC1
Mean 35.9
Standard deviation 11
Values 44 28
[31]
HepG2.C3A GPC1
Mean 3.16
Standard deviation 0.57
Values 2.8 3.6
[32]
HuH.7 GPC1
Mean 0.188
Standard deviation 0.13
Values 0.3 0.23 0.037
[33]
SNU475 GPC1
Mean 115
Standard deviation 39
Values 1.4e+02 88
[34]
THLE GPC1
Mean 55.5
Standard deviation 8.3
Values 50 61
[35]
liver GPC1
Mean 11.3
Standard deviation 3.4
Values 7.6 13 15 9.6
[36]
ref_hepatocyte B4GALT7
Mean 9.13
Standard deviation 4.3
Values 3.2 6.7 14 12 9.9
[37]
HepG2 B4GALT7
Mean 14.1
Standard deviation 0.49
Values 14 14
[38]
HepG2.C3A B4GALT7
Mean 13.9
Standard deviation 2.5
Values 16 12
[39]
HuH.7 B4GALT7
Mean 17
Standard deviation 4.6
Values 18 12 21
[40]
SNU475 B4GALT7
Mean 7.94
Standard deviation 1.7
Values 9.2 6.7
[41]
THLE B4GALT7
Mean 10
Standard deviation 0.3
Values 9.8 10
[42]
liver B4GALT7
Mean 6.54
Standard deviation 2.2
Values 5.5 5.1 9.8 5.7
[43]
ref_hepatocyte AGRN
Mean 5.08
Standard deviation 2.6
Values 4.9 9.5 3.2 4.4 3.4
[44]
HepG2 AGRN
Mean 201
Standard deviation 74
Values 2.5e+02 1.5e+02
[45]
HepG2.C3A AGRN
Mean 120
Standard deviation 34
Values 1.4e+02 95
[46]
HuH.7 AGRN
Mean 80.8
Standard deviation 15
Values 96 66 80
[47]
SNU475 AGRN
Mean 108
Standard deviation 64
Values 1.5e+02 63
[48]
THLE AGRN
Mean 62.4
Standard deviation 19
Values 49 76
[49]
liver AGRN
Mean 15.2
Standard deviation 13
Values 4 26 3.2 28
[50]
ref_hepatocyte GPC6
Mean 2.38
Standard deviation 1.5
Values 3.3 1.3 0.41 2.8 4
[51]
HepG2 GPC6
Mean 32
Standard deviation 10
Values 25 39
[52]
HepG2.C3A GPC6
Mean 16.1
Standard deviation 1.8
Values 15 17
[53]
HuH.7 GPC6
Mean 23.3
Standard deviation 7.4
Values 21 31 17
[54]
SNU475 GPC6
Mean 67.1
Standard deviation 28
Values 87 47
[55]
THLE GPC6
Mean 19.9
Standard deviation 5
Values 16 23
[56]
liver GPC6
Mean 32.3
Standard deviation 8.7
Values 38 30 21 40
[57]
ref_hepatocyte SDC3
Mean 1.04
Standard deviation 0.71
Values 0.11 0.84 0.73 1.7 1.8
[58]
HepG2 SDC3
Mean 16
Standard deviation 2.6
Values 18 14
[59]
HepG2.C3A SDC3
Mean 0.19
Standard deviation 0.035
Values 0.17 0.21
[60]
HuH.7 SDC3
Mean 2.95
Standard deviation 1.2
Values 4 1.7 3.2
[61]
SNU475 SDC3
Mean 16.7
Standard deviation 0.42
Values 17 16
[62]
THLE SDC3
Mean 22.7
Standard deviation 0.49
Values 22 23
[63]
liver SDC3
Mean 9.95
Standard deviation 2.5
Values 9.5 13 7.1 10
[64]
ref_hepatocyte DCN
Mean 0.734
Standard deviation 1.2
Values 0 0 0.17 0.72 2.8
[65]
HepG2 DCN
Mean 0.02
Standard deviation 0.0041
Values 0.023 0.017
[66]
HepG2.C3A DCN
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[67]
HuH.7 DCN
Mean 0.038
Standard deviation 0.019
Values 0.057 0.019 0.037
[68]
SNU475 DCN
Mean 3.92
Standard deviation 0.29
Values 3.7 4.1
[69]
THLE DCN
Mean 78.6
Standard deviation 48
Values 1.1e+02 44
[70]
liver DCN
Mean 54.1
Standard deviation 15
Values 60 51 70 35
[71]
ref_hepatocyte BGN
Mean 0.625
Standard deviation 0.62
Values 0.052 0 0.61 1.4 1
[72]
HepG2 BGN
Mean 5.39
Standard deviation 1.6
Values 6.5 4.3
[73]
HepG2.C3A BGN
Mean 0.127
Standard deviation 0.013
Values 0.14 0.12
[74]
HuH.7 BGN
Mean 0.0256
Standard deviation 0.029
Values 0.057 0.019 0
[75]
SNU475 BGN
Mean 3.94
Standard deviation 1.9
Values 2.6 5.3
[76]
THLE BGN
Mean 0.764
Standard deviation 0.37
Values 1 0.51
[77]
liver BGN
Mean 36.2
Standard deviation 29
Values 65 9.5 57 13
[78]
ref_hepatocyte HSPG2
Mean 0.417
Standard deviation 0.41
Values 1.1 0.16 0.49 0.16 0.18
[79]
HepG2 HSPG2
Mean 181
Standard deviation 62
Values 2.3e+02 1.4e+02
[80]
HepG2.C3A HSPG2
Mean 47.5
Standard deviation 2.4
Values 46 49
[81]
HuH.7 HSPG2
Mean 59.8
Standard deviation 39
Values 1e+02 34 40
[82]
SNU475 HSPG2
Mean 50.5
Standard deviation 35
Values 75 26
[83]
THLE HSPG2
Mean 63.4
Standard deviation 18
Values 50 76
[84]
liver HSPG2
Mean 49
Standard deviation 38
Values 14 64 22 96
[85]
ref_hepatocyte VCAN
Mean 0.409
Standard deviation 0.32
Values 0.014 0.17 0.6 0.47 0.8
[86]
HepG2 VCAN
Mean 24.2
Standard deviation 5.2
Values 21 28
[87]
HepG2.C3A VCAN
Mean 0.601
Standard deviation 0.27
Values 0.41 0.79
[88]
HuH.7 VCAN
Mean 10
Standard deviation 9.3
Values 6.1 21 3.4
[89]
SNU475 VCAN
Mean 2.11
Standard deviation 1.7
Values 0.9 3.3
[90]
THLE VCAN
Mean 46.4
Standard deviation 11
Values 39 54
[91]
liver VCAN
Mean 8.26
Standard deviation 6.7
Values 4.5 8.5 2.4 18
[92]
ref_hepatocyte GPC4
Mean 0.349
Standard deviation 0.51
Values 0.13 0.065 1.2 0 0.33
[93]
HepG2 GPC4
Mean 0.383
Standard deviation 0.074
Values 0.44 0.33
[94]
HepG2.C3A GPC4
Mean 0.0204
Standard deviation 0.0014
Values 0.019 0.021
[95]
HuH.7 GPC4
Mean 0.269
Standard deviation 0.25
Values 0.18 0.55 0.075
[96]
SNU475 GPC4
Mean 28.5
Standard deviation 18
Values 41 16
[97]
THLE GPC4
Mean 0.147
Standard deviation 0.048
Values 0.11 0.18
[98]
liver GPC4
Mean 0.949
Standard deviation 0.44
Values 0.71 1.1 0.51 1.5
[99]
ref_hepatocyte CSPG5
Mean 0.152
Standard deviation 0.19
Values 0 0.34 0 0.39 0.033
[100]
HepG2 CSPG5
Mean 0.145
Standard deviation 0.022
Values 0.16 0.13
[101]
HepG2.C3A CSPG5
Mean 0.0194
Standard deviation 0.027
Values 0.039 0
[102]
HuH.7 CSPG5
Mean 1.09
Standard deviation 0.56
Values 1.3 0.46 1.5
[103]
SNU475 CSPG5
Mean 0.62
Standard deviation 0.32
Values 0.39 0.85
[104]
THLE CSPG5
Mean 0.16
Standard deviation 0.016
Values 0.17 0.15
[105]
liver CSPG5
Mean 0.0462
Standard deviation 0.032
Values 0.024 0.043 0.026 0.093
[106]
ref_hepatocyte GPC5
Mean 0.0619
Standard deviation 0.066
Values 0 0 0.14 0.052 0.11
[107]
HepG2 GPC5
Mean 0.015
Standard deviation 0.0031
Values 0.017 0.013
[108]
HepG2.C3A GPC5
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[109]
HuH.7 GPC5
Mean 0.107
Standard deviation 0.094
Values 0.082 0.21 0.028
[110]
SNU475 GPC5
Mean 0.012
Standard deviation 0.0027
Values 0.014 0.01
[111]
THLE GPC5
Mean 0.0192
Standard deviation 0.01
Values 0.012 0.027
[112]
liver GPC5
Mean 1.04
Standard deviation 0.64
Values 2 0.83 0.72 0.64
[113]
ref_hepatocyte GPC2
Mean 0.0542
Standard deviation 0.044
Values 0.094 0 0.019 0.06 0.098
[114]
HepG2 GPC2
Mean 0.9
Standard deviation 0.41
Values 1.2 0.61
[115]
HepG2.C3A GPC2
Mean 0.541
Standard deviation 0.0087
Values 0.53 0.55
[116]
HuH.7 GPC2
Mean 2.11
Standard deviation 0.72
Values 2.1 1.4 2.8
[117]
SNU475 GPC2
Mean 1.01
Standard deviation 0.087
Values 0.95 1.1
[118]
THLE GPC2
Mean 0.506
Standard deviation 0.038
Values 0.53 0.48
[119]
liver GPC2
Mean 0.00918
Standard deviation 0.011
Values 0.024 0 0 0.013
[120]
ref_hepatocyte NCAN
Mean 0.0163
Standard deviation 0.036
Values 0 0 0.082 0 0
[121]
HepG2 NCAN
Mean 0.117
Standard deviation 0.12
Values 0.2 0.034
[122]
HepG2.C3A NCAN
Mean 0.0151
Standard deviation 0.0062
Values 0.019 0.011
[123]
HuH.7 NCAN
Mean 0.0731
Standard deviation 0.043
Values 0.041 0.12 0.056
[124]
SNU475 NCAN
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[125]
THLE NCAN
Mean 0.0207
Standard deviation 0.029
Values 0.041 0
[126]
liver NCAN
Mean 0.013
Standard deviation 0.015
Values 0.024 0.029 0 0
[127]
ref_hepatocyte CSPG4
Mean 0.0131
Standard deviation 0.018
Values 0.014 0 0.043 0 0.0081
[128]
HepG2 CSPG4
Mean 0.338
Standard deviation 0.09
Values 0.4 0.27
[129]
HepG2.C3A CSPG4
Mean 0.151
Standard deviation 0.062
Values 0.19 0.11
[130]
HuH.7 CSPG4
Mean 0.505
Standard deviation 0.16
Values 0.57 0.62 0.33
[131]
SNU475 CSPG4
Mean 3.45
Standard deviation 0.17
Values 3.6 3.3
[132]
THLE CSPG4
Mean 6.12
Standard deviation 2.4
Values 4.4 7.8
[133]
liver CSPG4
Mean 1.04
Standard deviation 1.2
Values 0.16 1.3 0.1 2.5
[134]
ref_hepatocyte BCAN
Mean 0.0065
Standard deviation 0.015
Values 0 0 0 0 0.033
[135]
HepG2 BCAN
Mean 4.23
Standard deviation 3.5
Values 6.7 1.8
[136]
HepG2.C3A BCAN
Mean 4.29
Standard deviation 0.91
Values 4.9 3.6
[137]
HuH.7 BCAN
Mean 1.21
Standard deviation 0.35
Values 1.3 1.5 0.83
[138]
SNU475 BCAN
Mean 1.96
Standard deviation 0.26
Values 2.1 1.8
[139]
THLE BCAN
Mean 0.527
Standard deviation 0.083
Values 0.59 0.47
[140]
liver BCAN
Mean 0.0604
Standard deviation 0.033
Values 0.071 0.029 0.1 0.04