REACTOME_DEADENYLATION_OF_MRNA Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 EIF4A1 Eukaryotic initiation factor 4A-I [1] [2] [3] [4] [5] [6] [7]
2 PABPC1 Polyadenylate-binding protein 1 [8] -0.28[9] -0.33[10] 0.01[11] -0.08[12] -0.34[13] -0.87[14]
3 EIF4A2 Eukaryotic initiation factor 4A-II [15] -0.36[16] -0.27[17] -0.01[18] -1.13[19] -1.14[20] -1.09[21]
4 EIF4B Eukaryotic translation initiation factor 4B [22] 0.97[23] 1.76[24] 1.55[25] 0.68[26] 0.82[27] 0.80[28]
5 EIF4G1 Eukaryotic translation initiation factor 4 gamma 1 [29] 1.25[30] 0.02[31] 0.01[32] 1.18[33] 1.34[34] 1.80[35]
6 EIF4A3 Eukaryotic initiation factor 4A-III [36] 0.12[37] -0.84[38] -1.03[39] -0.29[40] -0.28[41] -1.01[42]
7 PAIP1 Polyadenylate-binding protein-interacting protein 1 [43] -0.13[44] -0.14[45] -0.66[46] 0.59[47] 0.48[48] 0.13[49]
8 CNOT7 CCR4-NOT transcription complex subunit 7 [50] 0.24[51] 0.33[52] 0.33[53] 0.15[54] -0.01[55] 0.64[56]
9 EIF4E Eukaryotic translation initiation factor 4E [57] 0.51[58] 0.91[59] -0.15[60] 0.52[61] 1.32[62] 0.91[63]
10 TNKS1BP1 182 kDa tankyrase-1-binding protein [64] 0.58[65] -0.77[66] -0.75[67] 2.03[68] 1.71[69] 1.34[70]
11 CNOT8 CCR4-NOT transcription complex subunit 8 [71] 0.71[72] 0.87[73] 1.07[74] 1.10[75] 1.10[76] 0.50[77]
12 CNOT1 CCR4-NOT transcription complex subunit 1 [78] 3.28[79] 2.96[80] 2.98[81] 3.14[82] 3.50[83] 3.32[84]
13 PARN Poly(A)-specific ribonuclease PARN [85] 1.30[86] 0.22[87] -0.55[88] 0.76[89] 0.49[90] 0.68[91]
14 CNOT2 CCR4-NOT transcription complex subunit 2 [92] 0.68[93] 1.06[94] 0.58[95] 1.61[96] 1.25[97] 1.50[98]
15 CNOT3 CCR4-NOT transcription complex subunit 3 [99] 0.56[100] -0.14[101] 0.70[102] 1.38[103] 0.86[104] -0.60[105]
16 CNOT10 CCR4-NOT transcription complex subunit 10 [106] 0.48[107] 0.75[108] 1.37[109] 0.89[110] 1.43[111] 1.09[112]
17 CNOT4 CCR4-NOT transcription complex subunit 4 [113] -0.29[114] -0.75[115] -0.51[116] 0.95[117] 0.55[118] 1.27[119]
18 PAN2 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 [120] 0.72[121] 2.64[122] 1.45[123] 0.95[124] 1.92[125] 4.07[126]
19 CNOT6L CCR4-NOT transcription complex subunit 6-like [127] 1.75[128] 2.44[129] 1.67[130] 2.38[131] 2.39[132] 3.86[133]
20 PAN3 PAN2-PAN3 deadenylation complex subunit PAN3 [134] 1.26[135] 1.63[136] 1.33[137] 2.63[138] 1.98[139] 3.60[140]
21 CNOT6 CCR4-NOT transcription complex subunit 6 [141] 2.85[142] 2.75[143] 3.22[144] 3.83[145] 3.45[146] 2.39[147]
22 TUT7 [148] [149] [150] [151] [152] [153] [154]
23 CNOT11 CCR4-NOT transcription complex subunit 11 [155] [156] [157] [158] [159] [160] [161]
24 TUT4 [162] [163] [164] [165] [166] [167] [168]
25 CNOT9 CCR4-NOT transcription complex subunit 9 [169] [170] [171] [172] [173] [174] [175]
[1]
ref_hepatocyte EIF4A1
Mean 248
Standard deviation 1.5e+02
Values 1.4e+02 4.1e+02 3.9e+02 2e+02 95
[2]
HepG2 EIF4A1
Missing
[3]
HepG2.C3A EIF4A1
Missing
[4]
HuH.7 EIF4A1
Missing
[5]
SNU475 EIF4A1
Missing
[6]
THLE EIF4A1
Missing
[7]
liver EIF4A1
Missing
[8]
ref_hepatocyte PABPC1
Mean 229
Standard deviation 1.3e+02
Values 3.5e+02 3.7e+02 2.4e+02 1.1e+02 78
[9]
HepG2 PABPC1
Mean 321
Standard deviation 86
Values 3.8e+02 2.6e+02
[10]
HepG2.C3A PABPC1
Mean 375
Standard deviation 1.6e+02
Values 4.9e+02 2.6e+02
[11]
HuH.7 PABPC1
Mean 609
Standard deviation 32
Values 6.4e+02 6e+02 5.8e+02
[12]
SNU475 PABPC1
Mean 229
Standard deviation 21
Values 2.4e+02 2.1e+02
[13]
THLE PABPC1
Mean 251
Standard deviation 24
Values 2.3e+02 2.7e+02
[14]
liver PABPC1
Mean 106
Standard deviation 46
Values 1.6e+02 79 1.3e+02 57
[15]
ref_hepatocyte EIF4A2
Mean 146
Standard deviation 77
Values 2.7e+02 1.3e+02 1.6e+02 84 85
[16]
HepG2 EIF4A2
Mean 193
Standard deviation 22
Values 1.8e+02 2.1e+02
[17]
HepG2.C3A EIF4A2
Mean 247
Standard deviation 36
Values 2.7e+02 2.2e+02
[18]
HuH.7 EIF4A2
Mean 382
Standard deviation 1.1e+02
Values 2.8e+02 5e+02 3.6e+02
[19]
SNU475 EIF4A2
Mean 70.1
Standard deviation 12
Values 79 62
[20]
THLE EIF4A2
Mean 91.5
Standard deviation 0.3
Values 92 91
[21]
liver EIF4A2
Mean 57.9
Standard deviation 15
Values 53 80 48 50
[22]
ref_hepatocyte EIF4B
Mean 76.3
Standard deviation 32
Values 1.2e+02 82 86 49 43
[23]
HepG2 EIF4B
Mean 255
Standard deviation 11
Values 2.6e+02 2.5e+02
[24]
HepG2.C3A EIF4B
Mean 530
Standard deviation 1.8e+02
Values 6.6e+02 4e+02
[25]
HuH.7 EIF4B
Mean 590
Standard deviation 80
Values 5.6e+02 6.8e+02 5.3e+02
[26]
SNU475 EIF4B
Mean 129
Standard deviation 20
Values 1.4e+02 1.1e+02
[27]
THLE EIF4B
Mean 186
Standard deviation 19
Values 1.7e+02 2e+02
[28]
liver EIF4B
Mean 113
Standard deviation 68
Values 62 1.9e+02 51 1.5e+02
[29]
ref_hepatocyte EIF4G1
Mean 58.8
Standard deviation 19
Values 41 88 63 57 44
[30]
HepG2 EIF4G1
Mean 239
Standard deviation 2.2
Values 2.4e+02 2.4e+02
[31]
HepG2.C3A EIF4G1
Mean 122
Standard deviation 11
Values 1.1e+02 1.3e+02
[32]
HuH.7 EIF4G1
Mean 156
Standard deviation 42
Values 2e+02 1.2e+02 1.5e+02
[33]
SNU475 EIF4G1
Mean 140
Standard deviation 19
Values 1.5e+02 1.3e+02
[34]
THLE EIF4G1
Mean 207
Standard deviation 56
Values 1.7e+02 2.5e+02
[35]
liver EIF4G1
Mean 173
Standard deviation 23
Values 1.6e+02 1.7e+02 1.6e+02 2.1e+02
[36]
ref_hepatocyte EIF4A3
Mean 38.1
Standard deviation 25
Values 73 56 25 20 17
[37]
HepG2 EIF4A3
Mean 70.5
Standard deviation 3
Values 73 68
[38]
HepG2.C3A EIF4A3
Mean 43.7
Standard deviation 2.8
Values 42 46
[39]
HuH.7 EIF4A3
Mean 49.2
Standard deviation 18
Values 53 30 65
[40]
SNU475 EIF4A3
Mean 32.9
Standard deviation 3.1
Values 31 35
[41]
THLE EIF4A3
Mean 43.4
Standard deviation 7.9
Values 38 49
[42]
liver EIF4A3
Mean 16.1
Standard deviation 5.7
Values 21 12 21 11
[43]
ref_hepatocyte PAIP1
Mean 26.4
Standard deviation 2.7
Values 26 27 30 22 27
[44]
HepG2 PAIP1
Mean 41.1
Standard deviation 9.1
Values 35 48
[45]
HepG2.C3A PAIP1
Mean 49.1
Standard deviation 7.6
Values 44 54
[46]
HuH.7 PAIP1
Mean 43.9
Standard deviation 5.7
Values 43 39 50
[47]
SNU475 PAIP1
Mean 41.8
Standard deviation 6.2
Values 46 37
[48]
THLE PAIP1
Mean 51.1
Standard deviation 4.2
Values 54 48
[49]
liver PAIP1
Mean 24.4
Standard deviation 13
Values 43 15 26 14
[50]
ref_hepatocyte CNOT7
Mean 22.4
Standard deviation 8.4
Values 30 32 21 13 16
[51]
HepG2 CNOT7
Mean 45.3
Standard deviation 9.7
Values 38 52
[52]
HepG2.C3A CNOT7
Mean 57.8
Standard deviation 6.7
Values 53 62
[53]
HuH.7 CNOT7
Mean 74.2
Standard deviation 2.9
Values 77 71 75
[54]
SNU475 CNOT7
Mean 26.3
Standard deviation 0.76
Values 26 27
[55]
THLE CNOT7
Mean 30.9
Standard deviation 1.5
Values 32 30
[56]
liver CNOT7
Mean 29.6
Standard deviation 13
Values 44 22 37 16
[57]
ref_hepatocyte EIF4E
Mean 15
Standard deviation 8.3
Values 17 28 13 7.1 10
[58]
HepG2 EIF4E
Mean 36.5
Standard deviation 7.8
Values 31 42
[59]
HepG2.C3A EIF4E
Mean 57.7
Standard deviation 21
Values 43 72
[60]
HuH.7 EIF4E
Mean 35.6
Standard deviation 9.2
Values 41 25 41
[61]
SNU475 EIF4E
Mean 22.8
Standard deviation 0.41
Values 23 22
[62]
THLE EIF4E
Mean 52.1
Standard deviation 2.8
Values 50 54
[63]
liver EIF4E
Mean 24
Standard deviation 12
Values 33 16 36 12
[64]
ref_hepatocyte TNKS1BP1
Mean 11.8
Standard deviation 4.3
Values 5.1 9.8 15 15 14
[65]
HepG2 TNKS1BP1
Mean 30
Standard deviation 1.9
Values 31 29
[66]
HepG2.C3A TNKS1BP1
Mean 14.2
Standard deviation 3.8
Values 17 11
[67]
HuH.7 TNKS1BP1
Mean 18.5
Standard deviation 3.7
Values 22 15 19
[68]
SNU475 TNKS1BP1
Mean 50.8
Standard deviation 10
Values 58 44
[69]
THLE TNKS1BP1
Mean 53.6
Standard deviation 7.1
Values 49 59
[70]
liver TNKS1BP1
Mean 25.3
Standard deviation 14
Values 17 36 10 38
[71]
ref_hepatocyte CNOT8
Mean 9.07
Standard deviation 2.5
Values 12 8.6 5.7 10 8.2
[72]
HepG2 CNOT8
Mean 25.4
Standard deviation 5.2
Values 22 29
[73]
HepG2.C3A CNOT8
Mean 34.1
Standard deviation 5.1
Values 38 30
[74]
HuH.7 CNOT8
Mean 50.1
Standard deviation 8.4
Values 47 44 60
[75]
SNU475 CNOT8
Mean 20.5
Standard deviation 1.9
Values 22 19
[76]
THLE CNOT8
Mean 27
Standard deviation 3.2
Values 25 29
[77]
liver CNOT8
Mean 10.9
Standard deviation 2.6
Values 14 8.3 12 9.3
[78]
ref_hepatocyte CNOT1
Mean 8.47
Standard deviation 4.2
Values 16 7.4 8.4 5.5 5.4
[79]
HepG2 CNOT1
Mean 140
Standard deviation 43
Values 1.1e+02 1.7e+02
[80]
HepG2.C3A CNOT1
Mean 135
Standard deviation 8.6
Values 1.3e+02 1.4e+02
[81]
HuH.7 CNOT1
Mean 176
Standard deviation 52
Values 2.3e+02 1.6e+02 1.3e+02
[82]
SNU475 CNOT1
Mean 78.7
Standard deviation 1.2
Values 79 78
[83]
THLE CNOT1
Mean 133
Standard deviation 7.1
Values 1.3e+02 1.4e+02
[84]
liver CNOT1
Mean 71.6
Standard deviation 40
Values 36 1e+02 38 1.1e+02
[85]
ref_hepatocyte PARN
Mean 8.43
Standard deviation 4.9
Values 17 7.1 8.4 5.2 4.7
[86]
HepG2 PARN
Mean 35.5
Standard deviation 6.6
Values 31 40
[87]
HepG2.C3A PARN
Mean 20.2
Standard deviation 1.7
Values 19 21
[88]
HuH.7 PARN
Mean 15.2
Standard deviation 2.1
Values 17 13 16
[89]
SNU475 PARN
Mean 15
Standard deviation 0.41
Values 15 15
[90]
THLE PARN
Mean 16.4
Standard deviation 5.2
Values 13 20
[91]
liver PARN
Mean 11.5
Standard deviation 1.2
Values 10 12 13 10
[92]
ref_hepatocyte CNOT2
Mean 7.04
Standard deviation 1.3
Values 6.3 8.2 8.7 6.2 5.7
[93]
HepG2 CNOT2
Mean 19.3
Standard deviation 6.8
Values 14 24
[94]
HepG2.C3A CNOT2
Mean 30
Standard deviation 5
Values 27 34
[95]
HuH.7 CNOT2
Mean 27.6
Standard deviation 1.4
Values 29 28 26
[96]
SNU475 CNOT2
Mean 22.7
Standard deviation 1.9
Values 24 21
[97]
THLE CNOT2
Mean 23.2
Standard deviation 1.4
Values 22 24
[98]
liver CNOT2
Mean 16.8
Standard deviation 2.6
Values 20 17 16 14
[99]
ref_hepatocyte CNOT3
Mean 6.59
Standard deviation 6.4
Values 3.1 1.7 17 7.4 3.3
[100]
HepG2 CNOT3
Mean 16.6
Standard deviation 1.3
Values 17 16
[101]
HepG2.C3A CNOT3
Mean 12.3
Standard deviation 1.5
Values 13 11
[102]
HuH.7 CNOT3
Mean 28.1
Standard deviation 3
Values 30 25 29
[103]
SNU475 CNOT3
Mean 18.2
Standard deviation 0.65
Values 19 18
[104]
THLE CNOT3
Mean 16.5
Standard deviation 1.8
Values 15 18
[105]
liver CNOT3
Mean 3.7
Standard deviation 0.74
Values 4.1 2.6 4 4.1
[106]
ref_hepatocyte CNOT10
Mean 4.56
Standard deviation 0.49
Values 4.7 5.2 4.5 4.5 3.8
[107]
HepG2 CNOT10
Mean 10.8
Standard deviation 2.1
Values 9.4 12
[108]
HepG2.C3A CNOT10
Mean 15.7
Standard deviation 0.95
Values 15 16
[109]
HuH.7 CNOT10
Mean 31.1
Standard deviation 1.2
Values 31 32 30
[110]
SNU475 CNOT10
Mean 8.9
Standard deviation 1.9
Values 7.6 10
[111]
THLE CNOT10
Mean 17
Standard deviation 1.1
Values 16 18
[112]
liver CNOT10
Mean 8.23
Standard deviation 1.8
Values 8.3 7.8 11 6.2
[113]
ref_hepatocyte CNOT4
Mean 3.66
Standard deviation 1.4
Values 3.2 4.1 5.8 2.2 3.1
[114]
HepG2 CNOT4
Mean 5.09
Standard deviation 1.1
Values 4.3 5.9
[115]
HepG2.C3A CNOT4
Mean 4.45
Standard deviation 0.073
Values 4.5 4.4
[116]
HuH.7 CNOT4
Mean 6.77
Standard deviation 0.65
Values 7.4 6.8 6.1
[117]
SNU475 CNOT4
Mean 7.48
Standard deviation 0.28
Values 7.3 7.7
[118]
THLE CNOT4
Mean 7.42
Standard deviation 0.36
Values 7.2 7.7
[119]
liver CNOT4
Mean 7.49
Standard deviation 2.9
Values 10 5.1 9.9 4.8
[120]
ref_hepatocyte PAN2
Mean 2.52
Standard deviation 2.1
Values 1.3 0.51 1.1 5.2 4.5
[121]
HepG2 PAN2
Mean 7.08
Standard deviation 0.2
Values 6.9 7.2
[122]
HepG2.C3A PAN2
Mean 32.3
Standard deviation 4.4
Values 35 29
[123]
HuH.7 PAN2
Mean 18.1
Standard deviation 4.4
Values 14 23 17
[124]
SNU475 PAN2
Mean 5.13
Standard deviation 1.1
Values 5.9 4.3
[125]
THLE PAN2
Mean 13.2
Standard deviation 1.8
Values 14 12
[126]
liver PAN2
Mean 35.9
Standard deviation 7.3
Values 26 38 36 44
[127]
ref_hepatocyte CNOT6L
Mean 1.65
Standard deviation 0.86
Values 3.1 1.5 1.1 0.91 1.7
[128]
HepG2 CNOT6L
Mean 9.5
Standard deviation 3.7
Values 6.9 12
[129]
HepG2.C3A CNOT6L
Mean 18.4
Standard deviation 2.2
Values 20 17
[130]
HuH.7 CNOT6L
Mean 13.8
Standard deviation 4.3
Values 14 18 9.7
[131]
SNU475 CNOT6L
Mean 9.1
Standard deviation 0.058
Values 9.1 9.1
[132]
THLE CNOT6L
Mean 12
Standard deviation 2
Values 11 13
[133]
liver CNOT6L
Mean 20.4
Standard deviation 4.6
Values 19 27 16 20
[134]
ref_hepatocyte PAN3
Mean 1.43
Standard deviation 1.1
Values 3.3 1.2 1.4 0.3 0.93
[135]
HepG2 PAN3
Mean 5.83
Standard deviation 0.85
Values 5.2 6.4
[136]
HepG2.C3A PAN3
Mean 9.07
Standard deviation 1.1
Values 9.8 8.3
[137]
HuH.7 PAN3
Mean 9.43
Standard deviation 1.4
Values 8.6 11 8.7
[138]
SNU475 PAN3
Mean 9.3
Standard deviation 1.8
Values 11 8
[139]
THLE PAN3
Mean 7.77
Standard deviation 0.62
Values 7.3 8.2
[140]
liver PAN3
Mean 14.7
Standard deviation 6.4
Values 24 12 13 10
[141]
ref_hepatocyte CNOT6
Mean 1.39
Standard deviation 0.83
Values 2.8 1.4 1.3 0.75 0.78
[142]
HepG2 CNOT6
Mean 17
Standard deviation 4
Values 14 20
[143]
HepG2.C3A CNOT6
Mean 19.2
Standard deviation 2.8
Values 17 21
[144]
HuH.7 CNOT6
Mean 34
Standard deviation 8.1
Values 43 27 32
[145]
SNU475 CNOT6
Mean 20.9
Standard deviation 1.8
Values 22 20
[146]
THLE CNOT6
Mean 21
Standard deviation 2.7
Values 19 23
[147]
liver CNOT6
Mean 6.17
Standard deviation 2.1
Values 4.3 8.7 4.5 7.1
[148]
ref_hepatocyte TUT7
Missing
[149]
HepG2 TUT7
Missing
[150]
HepG2.C3A TUT7
Missing
[151]
HuH.7 TUT7
Missing
[152]
SNU475 TUT7
Missing
[153]
THLE TUT7
Missing
[154]
liver TUT7
Missing
[155]
ref_hepatocyte CNOT11
Missing
[156]
HepG2 CNOT11
Mean 55.3
Standard deviation 3.3
Values 53 58
[157]
HepG2.C3A CNOT11
Mean 71.5
Standard deviation 0.066
Values 72 71
[158]
HuH.7 CNOT11
Mean 69.4
Standard deviation 10
Values 76 58 75
[159]
SNU475 CNOT11
Mean 19
Standard deviation 2
Values 20 18
[160]
THLE CNOT11
Mean 22.8
Standard deviation 2.8
Values 21 25
[161]
liver CNOT11
Mean 8.79
Standard deviation 2.2
Values 12 7 9.8 6.9
[162]
ref_hepatocyte TUT4
Missing
[163]
HepG2 TUT4
Missing
[164]
HepG2.C3A TUT4
Missing
[165]
HuH.7 TUT4
Missing
[166]
SNU475 TUT4
Missing
[167]
THLE TUT4
Missing
[168]
liver TUT4
Missing
[169]
ref_hepatocyte CNOT9
Missing
[170]
HepG2 CNOT9
Missing
[171]
HepG2.C3A CNOT9
Missing
[172]
HuH.7 CNOT9
Missing
[173]
SNU475 CNOT9
Missing
[174]
THLE CNOT9
Missing
[175]
liver CNOT9
Missing