REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | EIF4A1 | Eukaryotic initiation factor 4A-I | [1] | [2] | [3] | [4] | [5] | [6] | [7] |
2 | PABPC1 | Polyadenylate-binding protein 1 | [8] | -0.29[9] | -0.31[10] | 0.08[11] | -0.22[12] | -0.43[13] | -1.02[14] |
3 | EIF4A2 | Eukaryotic initiation factor 4A-II | [15] | -0.37[16] | -0.26[17] | 0.06[18] | -1.27[19] | -1.24[20] | -1.24[21] |
4 | EIF4B | Eukaryotic translation initiation factor 4B | [22] | 0.96[23] | 1.77[24] | 1.62[25] | 0.54[26] | 0.73[27] | 0.65[28] |
5 | EIF4G1 | Eukaryotic translation initiation factor 4 gamma 1 | [29] | 1.25[30] | 0.03[31] | 0.08[32] | 1.04[33] | 1.25[34] | 1.65[35] |
6 | EIF4A3 | Eukaryotic initiation factor 4A-III | [36] | 0.11[37] | -0.83[38] | -0.96[39] | -0.42[40] | -0.37[41] | -1.15[42] |
7 | LSM3 | U6 snRNA-associated Sm-like protein LSm3 | [43] | -1.72[44] | -1.57[45] | -1.79[46] | -1.48[47] | -1.15[48] | -1.13[49] |
8 | LSM4 | U6 snRNA-associated Sm-like protein LSm4 | [50] | -0.26[51] | -0.05[52] | 0.48[53] | -0.77[54] | 0.12[55] | -0.71[56] |
9 | LSM2 | U6 snRNA-associated Sm-like protein LSm2 | [57] | -1.18[58] | -1.48[59] | -1.86[60] | -1.18[61] | -1.78[62] | -3.06[63] |
10 | LSM7 | U6 snRNA-associated Sm-like protein LSm7 | [64] | -1.16[65] | -0.91[66] | -1.90[67] | -2.30[68] | -2.06[69] | -2.61[70] |
11 | LSM1 | U6 snRNA-associated Sm-like protein LSm1 | [71] | -1.68[72] | -1.94[73] | -1.81[74] | -1.74[75] | -1.71[76] | -1.43[77] |
12 | PAIP1 | Polyadenylate-binding protein-interacting protein 1 | [78] | -0.13[79] | -0.13[80] | -0.59[81] | 0.45[82] | 0.39[83] | -0.02[84] |
13 | CNOT7 | CCR4-NOT transcription complex subunit 7 | [85] | 0.24[86] | 0.34[87] | 0.40[88] | 0.02[89] | -0.10[90] | 0.49[91] |
14 | WDR61 | WD repeat-containing protein 61 | [92] | -0.67[93] | -1.07[94] | -1.33[95] | -0.77[96] | -0.89[97] | -0.34[98] |
15 | EXOSC4 | Exosome complex component RRP41 | [99] | -1.15[100] | -1.20[101] | -2.21[102] | -1.18[103] | -2.04[104] | -1.07[105] |
16 | EXOSC7 | Exosome complex component RRP42 | [106] | -0.99[107] | -1.42[108] | -1.21[109] | -2.05[110] | -1.28[111] | -1.25[112] |
17 | EXOSC3 | Exosome complex component RRP40 | [113] | -0.74[114] | -1.26[115] | -0.91[116] | -1.27[117] | -0.79[118] | -1.22[119] |
18 | EIF4E | Eukaryotic translation initiation factor 4E | [120] | 0.51[121] | 0.92[122] | -0.08[123] | 0.39[124] | 1.23[125] | 0.77[126] |
19 | LSM6 | U6 snRNA-associated Sm-like protein LSm6 | [127] | -1.75[128] | -2.17[129] | -2.11[130] | -2.19[131] | -1.94[132] | -1.75[133] |
20 | TNKS1BP1 | 182 kDa tankyrase-1-binding protein | [134] | 0.57[135] | -0.76[136] | -0.68[137] | 1.89[138] | 1.62[139] | 1.19[140] |
21 | EXOSC9 | Exosome complex component RRP45 | [141] | -0.96[142] | -0.94[143] | -1.83[144] | -0.78[145] | 0.72[146] | -1.54[147] |
22 | LSM5 | U6 snRNA-associated Sm-like protein LSm5 | [148] | 0.09[149] | 0.66[150] | 0.01[151] | -0.02[152] | -0.01[153] | -0.05[154] |
23 | EXOSC5 | Exosome complex component RRP46 | [155] | -0.57[156] | -0.96[157] | -0.25[158] | -1.25[159] | -1.00[160] | -0.47[161] |
24 | CNOT8 | CCR4-NOT transcription complex subunit 8 | [162] | 0.71[163] | 0.89[164] | 1.14[165] | 0.97[166] | 1.01[167] | 0.35[168] |
25 | CNOT1 | CCR4-NOT transcription complex subunit 1 | [169] | 3.27[170] | 2.97[171] | 3.05[172] | 3.00[173] | 3.41[174] | 3.17[175] |
26 | PARN | Poly(A)-specific ribonuclease PARN | [176] | 1.30[177] | 0.23[178] | -0.48[179] | 0.62[180] | 0.39[181] | 0.53[182] |
27 | HBS1L | HBS1-like protein | [183] | 1.46[184] | 1.39[185] | 1.34[186] | 2.11[187] | 1.81[188] | 2.23[189] |
28 | DDX6 | Probable ATP-dependent RNA helicase DDX6 | [190] | 1.87[191] | 1.08[192] | 0.93[193] | 2.75[194] | 2.03[195] | 2.36[196] |
29 | DCPS | m7GpppX diphosphatase | [197] | -0.42[198] | -1.25[199] | -1.92[200] | 0.33[201] | -0.91[202] | 0.72[203] |
30 | EXOSC2 | Exosome complex component RRP4 | [204] | 0.60[205] | 0.01[206] | -0.04[207] | 0.34[208] | 1.10[209] | -0.09[210] |
31 | CNOT2 | CCR4-NOT transcription complex subunit 2 | [211] | 0.68[212] | 1.07[213] | 0.64[214] | 1.48[215] | 1.16[216] | 1.35[217] |
32 | EXOSC1 | Exosome complex component CSL4 | [218] | 0.28[219] | 0.54[220] | 0.48[221] | -0.24[222] | 0.50[223] | -0.36[224] |
33 | EXOSC6 | Exosome complex component MTR3 | [225] | 0.15[226] | -0.24[227] | -1.83[228] | -0.39[229] | 0.01[230] | -0.04[231] |
34 | CNOT3 | CCR4-NOT transcription complex subunit 3 | [232] | 0.55[233] | -0.12[234] | 0.76[235] | 1.25[236] | 0.76[237] | -0.74[238] |
35 | SKIV2L | Helicase SKI2W | [239] | 2.20[240] | 1.76[241] | 0.75[242] | 2.77[243] | 1.58[244] | 2.19[245] |
36 | EXOSC8 | Exosome complex component RRP43 | [246] | 0.52[247] | 0.93[248] | 0.75[249] | -0.07[250] | 0.80[251] | -0.07[252] |
37 | EDC4 | Enhancer of mRNA-decapping protein 4 | [253] | 1.98[254] | 1.66[255] | 1.42[256] | 2.23[257] | 1.88[258] | 1.53[259] |
38 | TTC37 | Tetratricopeptide repeat protein 37 | [260] | 1.00[261] | 2.51[262] | 1.58[263] | 3.05[264] | 2.62[265] | 3.28[266] |
39 | PATL1 | Protein PAT1 homolog 1 | [267] | 1.62[268] | 1.05[269] | 2.43[270] | 2.31[271] | 2.27[272] | 1.67[273] |
40 | CNOT10 | CCR4-NOT transcription complex subunit 10 | [274] | 0.47[275] | 0.76[276] | 1.44[277] | 0.75[278] | 1.34[279] | 0.94[280] |
41 | CNOT4 | CCR4-NOT transcription complex subunit 4 | [281] | -0.30[282] | -0.74[283] | -0.44[284] | 0.82[285] | 0.46[286] | 1.13[287] |
42 | EDC3 | Enhancer of mRNA-decapping protein 3 | [288] | 1.96[289] | 1.27[290] | 1.75[291] | 2.51[292] | 1.98[293] | 1.04[294] |
43 | DIS3 | Exosome complex exonuclease RRP44 | [295] | 1.27[296] | 1.88[297] | 2.19[298] | 2.46[299] | 2.32[300] | 2.55[301] |
44 | DCP1B | mRNA-decapping enzyme 1B | [302] | 0.70[303] | 0.13[304] | 0.22[305] | -0.51[306] | 0.00[307] | 0.16[308] |
45 | PAN2 | PAN2-PAN3 deadenylation complex catalytic subunit PAN2 | [309] | 0.71[310] | 2.65[311] | 1.52[312] | 0.81[313] | 1.82[314] | 3.92[315] |
46 | DCP1A | mRNA-decapping enzyme 1A | [316] | 2.19[317] | 2.15[318] | 1.22[319] | 2.05[320] | 2.74[321] | 3.36[322] |
47 | CNOT6L | CCR4-NOT transcription complex subunit 6-like | [323] | 1.75[324] | 2.45[325] | 1.74[326] | 2.25[327] | 2.30[328] | 3.71[329] |
48 | DCP2 | m7GpppN-mRNA hydrolase | [330] | 2.16[331] | 3.46[332] | 2.25[333] | 3.10[334] | 2.80[335] | 3.80[336] |
49 | PAN3 | PAN2-PAN3 deadenylation complex subunit PAN3 | [337] | 1.26[338] | 1.65[339] | 1.40[340] | 2.49[341] | 1.88[342] | 3.45[343] |
50 | CNOT6 | CCR4-NOT transcription complex subunit 6 | [344] | 2.84[345] | 2.76[346] | 3.28[347] | 3.70[348] | 3.36[349] | 2.24[350] |
51 | XRN1 | 5'-3' exoribonuclease 1 | [351] | 1.21[352] | 2.31[353] | 2.33[354] | 3.61[355] | 3.29[356] | 5.09[357] |
52 | TUT4 | [358] | [359] | [360] | [361] | [362] | [363] | [364] | |
53 | CNOT9 | CCR4-NOT transcription complex subunit 9 | [365] | [366] | [367] | [368] | [369] | [370] | [371] |
54 | NT5C3B | 7-methylguanosine phosphate-specific 5'-nucleotidase | [372] | [373] | [374] | [375] | [376] | [377] | [378] |
55 | TUT7 | [379] | [380] | [381] | [382] | [383] | [384] | [385] | |
56 | CNOT11 | CCR4-NOT transcription complex subunit 11 | [386] | [387] | [388] | [389] | [390] | [391] | [392] |