REACTOME_DCC_MEDIATED_ATTRACTIVE_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CDC42 Cell division control protein 42 homolog [1] -0.82[2] -0.34[3] -1.04[4] -0.67[5] -1.31[6] -1.85[7]
2 RAC1 Ras-related C3 botulinum toxin substrate 1 [8] -0.39[9] -0.96[10] 0.06[11] -0.13[12] -0.06[13] -0.73[14]
3 ABLIM3 Actin-binding LIM protein 3 [15] -2.42[16] -8.00[17] -2.56[18] -1.94[19] 0.55[20] 1.20[21]
4 NCK1 Cytoplasmic protein NCK1 [22] -1.59[23] -1.73[24] -1.31[25] -0.70[26] -0.51[27] -0.24[28]
5 ABLIM1 Actin-binding LIM protein 1 [29] 2.13[30] 1.84[31] 0.92[32] 0.19[33] -2.88[34] 1.58[35]
6 PTK2 Focal adhesion kinase 1 [36] 0.74[37] 0.99[38] 1.68[39] 1.81[40] 1.09[41] 0.99[42]
7 WASL Neural Wiskott-Aldrich syndrome protein [43] -0.48[44] 0.36[45] 1.07[46] 0.96[47] 0.21[48] 1.36[49]
8 TRIO Triple functional domain protein [50] 2.00[51] 1.50[52] 2.06[53] 2.46[54] 3.44[55] 2.99[56]
9 SRC Proto-oncogene tyrosine-protein kinase Src [57] 3.03[58] 2.77[59] 2.09[60] 2.26[61] 1.52[62] -0.62[63]
10 DOCK1 Dedicator of cytokinesis protein 1 [64] 1.99[65] 2.28[66] 2.58[67] -2.79[68] 2.10[69] 2.75[70]
11 FYN Tyrosine-protein kinase Fyn [71] 0.95[72] -7.89[73] 0.99[74] 1.33[75] 2.94[76] 1.20[77]
12 NTN1 Netrin-1 [78] -2.16[79] -3.08[80] 0.80[81] -4.79[82] -2.42[83] 3.51[84]
13 ABLIM2 Actin-binding LIM protein 2 [85] 0.14[86] -3.11[87] -0.57[88] 0.56[89] 0.50[90] 2.42[91]
14 DCC Netrin receptor DCC [92] [93] [94] [95] [96] [97] [98]
[1]
ref_hepatocyte CDC42
Mean 121
Standard deviation 1e+02
Values 1.6e+02 2.8e+02 75 45 46
[2]
HepG2 CDC42
Mean 150
Standard deviation 13
Values 1.4e+02 1.6e+02
[3]
HepG2.C3A CDC42
Mean 220
Standard deviation 55
Values 1.8e+02 2.6e+02
[4]
HuH.7 CDC42
Mean 105
Standard deviation 19
Values 1.2e+02 83 1.1e+02
[5]
SNU475 CDC42
Mean 153
Standard deviation 20
Values 1.7e+02 1.4e+02
[6]
THLE CDC42
Mean 104
Standard deviation 15
Values 93 1.1e+02
[7]
liver CDC42
Mean 40.5
Standard deviation 9.1
Values 42 43 49 28
[8]
ref_hepatocyte RAC1
Mean 52
Standard deviation 20
Values 28 59 81 45 47
[9]
HepG2 RAC1
Mean 87.4
Standard deviation 1.9
Values 89 86
[10]
HepG2.C3A RAC1
Mean 62
Standard deviation 7.4
Values 67 57
[11]
HuH.7 RAC1
Mean 97.2
Standard deviation 9.7
Values 1e+02 86 1e+02
[12]
SNU475 RAC1
Mean 96.5
Standard deviation 10
Values 89 1e+02
[13]
THLE RAC1
Mean 107
Standard deviation 19
Values 94 1.2e+02
[14]
liver RAC1
Mean 37.8
Standard deviation 32
Values 63 12 67 9.5
[15]
ref_hepatocyte ABLIM3
Mean 13.9
Standard deviation 8.8
Values 1.1 10 17 25 16
[16]
HepG2 ABLIM3
Mean 5.73
Standard deviation 1.7
Values 6.9 4.6
[17]
HepG2.C3A ABLIM3
Mean 0.125
Standard deviation 0.071
Values 0.17 0.075
[18]
HuH.7 ABLIM3
Mean 4.21
Standard deviation 2.4
Values 3.1 6.9 2.6
[19]
SNU475 ABLIM3
Mean 7.32
Standard deviation 4.7
Values 4 11
[20]
THLE ABLIM3
Mean 43.4
Standard deviation 9.3
Values 37 50
[21]
liver ABLIM3
Mean 38.5
Standard deviation 17
Values 22 43 28 61
[22]
ref_hepatocyte NCK1
Mean 11
Standard deviation 7.6
Values 4.9 23 13 6.3 7.3
[23]
HepG2 NCK1
Mean 8.05
Standard deviation 1.5
Values 7 9.1
[24]
HepG2.C3A NCK1
Mean 7.7
Standard deviation 1.8
Values 6.4 9
[25]
HuH.7 NCK1
Mean 7.97
Standard deviation 0.27
Values 7.7 7.9 8.2
[26]
SNU475 NCK1
Mean 13.7
Standard deviation 1.9
Values 15 12
[27]
THLE NCK1
Mean 16.6
Standard deviation 0.3
Values 16 17
[28]
liver NCK1
Mean 11.3
Standard deviation 2.9
Values 15 11 12 7.7
[29]
ref_hepatocyte ABLIM1
Mean 9.62
Standard deviation 9.2
Values 9.4 25 8.6 2.8 2.3
[30]
HepG2 ABLIM1
Mean 92.7
Standard deviation 15
Values 82 1e+02
[31]
HepG2.C3A ABLIM1
Mean 79.6
Standard deviation 20
Values 66 94
[32]
HuH.7 ABLIM1
Mean 32.6
Standard deviation 9.1
Values 43 27 28
[33]
SNU475 ABLIM1
Mean 22.2
Standard deviation 4.6
Values 25 19
[34]
THLE ABLIM1
Mean 2.8
Standard deviation 0.36
Values 3.1 2.5
[35]
liver ABLIM1
Mean 34.7
Standard deviation 8.8
Values 27 47 34 31
[36]
ref_hepatocyte PTK2
Mean 8.92
Standard deviation 4.8
Values 15 11 11 4.1 3.9
[37]
HepG2 PTK2
Mean 32.8
Standard deviation 5.2
Values 29 36
[38]
HepG2.C3A PTK2
Mean 40.9
Standard deviation 2.3
Values 43 39
[39]
HuH.7 PTK2
Mean 51.1
Standard deviation 2.8
Values 53 52 48
[40]
SNU475 PTK2
Mean 63.1
Standard deviation 3.5
Values 66 61
[41]
THLE PTK2
Mean 40.6
Standard deviation 3.7
Values 38 43
[42]
liver PTK2
Mean 21.5
Standard deviation 4.9
Values 19 27 16 24
[43]
ref_hepatocyte WASL
Mean 8.59
Standard deviation 2.4
Values 12 10 6.2 6.4 8.7
[44]
HepG2 WASL
Mean 13.6
Standard deviation 3.9
Values 11 16
[45]
HepG2.C3A WASL
Mean 25.4
Standard deviation 2.9
Values 28 23
[46]
HuH.7 WASL
Mean 32.2
Standard deviation 9.3
Values 28 43 25
[47]
SNU475 WASL
Mean 33.9
Standard deviation 2.2
Values 35 32
[48]
THLE WASL
Mean 21.2
Standard deviation 0.65
Values 21 22
[49]
liver WASL
Mean 26.7
Standard deviation 9.5
Values 39 19 30 19
[50]
ref_hepatocyte TRIO
Mean 3.94
Standard deviation 3.8
Values 2 7.3 8.8 0.78 0.78
[51]
HepG2 TRIO
Mean 34.8
Standard deviation 1.6
Values 34 36
[52]
HepG2.C3A TRIO
Mean 25.8
Standard deviation 1.3
Values 27 25
[53]
HuH.7 TRIO
Mean 29.3
Standard deviation 13
Values 28 43 18
[54]
SNU475 TRIO
Mean 44.1
Standard deviation 0.53
Values 44 44
[55]
THLE TRIO
Mean 91.3
Standard deviation 18
Values 1e+02 79
[56]
liver TRIO
Mean 37.7
Standard deviation 37
Values 7.6 72 4.7 67
[57]
ref_hepatocyte SRC
Mean 3.67
Standard deviation 3.6
Values 9.6 4.7 2.2 0.77 1.2
[58]
HepG2 SRC
Mean 66
Standard deviation 21
Values 81 51
[59]
HepG2.C3A SRC
Mean 58.1
Standard deviation 18
Values 71 45
[60]
HuH.7 SRC
Mean 27.9
Standard deviation 2
Values 28 29 26
[61]
SNU475 SRC
Mean 35.6
Standard deviation 3.5
Values 38 33
[62]
THLE SRC
Mean 22.5
Standard deviation 2.7
Values 21 24
[63]
liver SRC
Mean 2.9
Standard deviation 1
Values 4.1 2.5 1.7 3.2
[64]
ref_hepatocyte DOCK1
Mean 2.65
Standard deviation 1.4
Values 5 3 2.1 1.6 1.5
[65]
HepG2 DOCK1
Mean 23.1
Standard deviation 5.8
Values 19 27
[66]
HepG2.C3A DOCK1
Mean 29.8
Standard deviation 3.1
Values 28 32
[67]
HuH.7 DOCK1
Mean 28.4
Standard deviation 6
Values 35 23 27
[68]
SNU475 DOCK1
Mean 0.775
Standard deviation 0.14
Values 0.88 0.67
[69]
THLE DOCK1
Mean 24.3
Standard deviation 4.6
Values 21 28
[70]
liver DOCK1
Mean 21.5
Standard deviation 13
Values 8.5 36 13 29
[71]
ref_hepatocyte FYN
Mean 2.1
Standard deviation 2.2
Values 2.2 0.039 0.23 2.6 5.5
[72]
HepG2 FYN
Mean 8.91
Standard deviation 0.7
Values 9.4 8.4
[73]
HepG2.C3A FYN
Mean 0.0204
Standard deviation 0.0014
Values 0.019 0.021
[74]
HuH.7 FYN
Mean 7.43
Standard deviation 2.2
Values 8.9 4.8 8.5
[75]
SNU475 FYN
Mean 10.7
Standard deviation 2.5
Values 12 8.9
[76]
THLE FYN
Mean 34.5
Standard deviation 4.9
Values 38 31
[77]
liver FYN
Mean 5.84
Standard deviation 2.1
Values 8.9 4.4 5.1 5
[78]
ref_hepatocyte NTN1
Mean 0.538
Standard deviation 0.57
Values 0 0.22 0.55 1.5 0.45
[79]
HepG2 NTN1
Mean 0.266
Standard deviation 0.22
Values 0.42 0.11
[80]
HepG2.C3A NTN1
Mean 0.147
Standard deviation 0.011
Values 0.16 0.14
[81]
HuH.7 NTN1
Mean 1.68
Standard deviation 0.15
Values 1.6 1.9 1.6
[82]
SNU475 NTN1
Mean 0.0393
Standard deviation 0.016
Values 0.028 0.051
[83]
THLE NTN1
Mean 0.215
Standard deviation 0.056
Values 0.25 0.18
[84]
liver NTN1
Mean 7.41
Standard deviation 5
Values 3.7 13 2.8 9.9
[85]
ref_hepatocyte ABLIM2
Mean 0.147
Standard deviation 0.2
Values 0 0.091 0.49 0.16 0
[86]
HepG2 ABLIM2
Mean 0.357
Standard deviation 0.18
Values 0.48 0.23
[87]
HepG2.C3A ABLIM2
Mean 0.0394
Standard deviation 0.041
Values 0.068 0.011
[88]
HuH.7 ABLIM2
Mean 0.178
Standard deviation 0.036
Values 0.18 0.21 0.14
[89]
SNU475 ABLIM2
Mean 0.44
Standard deviation 0.038
Values 0.41 0.47
[90]
THLE ABLIM2
Mean 0.445
Standard deviation 0.22
Values 0.6 0.29
[91]
liver ABLIM2
Mean 0.952
Standard deviation 0.25
Values 0.85 0.71 0.95 1.3
[92]
ref_hepatocyte DCC
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[93]
HepG2 DCC
Mean 0
Standard deviation 0
Values 0 0
[94]
HepG2.C3A DCC
Mean 0
Standard deviation 0
Values 0 0
[95]
HuH.7 DCC
Mean 0
Standard deviation 0
Values 0 0 0
[96]
SNU475 DCC
Mean 0.0228
Standard deviation 0.032
Values 0 0.046
[97]
THLE DCC
Mean 0
Standard deviation 0
Values 0 0
[98]
liver DCC
Mean 0.0171
Standard deviation 0.02
Values 0 0.029 0 0.04