REACTOME_DAP12_INTERACTIONS | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | B2M | Beta-2-microglobulin | [1] | -1.45[2] | -1.21[3] | -1.73[4] | -0.79[5] | -0.56[6] | -0.06[7] |
2 | HLA-C | HLA class I histocompatibility antigen, Cw-17 alpha chain | [8] | -0.19[9] | -0.83[10] | -4.56[11] | -0.55[12] | -0.13[13] | -1.15[14] |
3 | HLA-B | HLA class I histocompatibility antigen, B-73 alpha chain | [15] | -1.16[16] | -2.46[17] | -6.67[18] | 0.89[19] | 0.26[20] | -0.80[21] |
4 | HLA-E | HLA class I histocompatibility antigen, alpha chain E | [22] | 0.01[23] | -0.11[24] | -0.41[25] | 0.38[26] | -0.61[27] | 0.72[28] |
5 | RAC1 | Ras-related C3 botulinum toxin substrate 1 | [29] | 1.44[30] | 1.14[31] | 1.99[32] | 0.50[33] | 0.86[34] | -0.43[35] |
6 | GRB2 | Growth factor receptor-bound protein 2 | [36] | 3.03[37] | 2.90[38] | 3.15[39] | 1.04[40] | 1.33[41] | 0.84[42] |
7 | SHC1 | SHC-transforming protein 1 | [43] | 3.00[44] | 3.25[45] | 3.46[46] | 3.14[47] | 3.00[48] | 1.32[49] |
8 | NRAS | GTPase NRas | [50] | 2.46[51] | 2.93[52] | 3.47[53] | 1.48[54] | 1.43[55] | 0.29[56] |
9 | TYROBP | TYRO protein tyrosine kinase-binding protein | [57] | -8.12[58] | [59] | [60] | -8.57[61] | [62] | -1.12[63] |
10 | HRAS | GTPase HRas | [64] | 0.83[65] | 0.15[66] | -0.51[67] | -0.46[68] | -0.30[69] | -2.12[70] |
11 | KRAS | GTPase KRas | [71] | 1.32[72] | 1.33[73] | 3.06[74] | 1.29[75] | 1.32[76] | 1.21[77] |
12 | VAV2 | Guanine nucleotide exchange factor VAV2 | [78] | 3.13[79] | 3.41[80] | 3.04[81] | -0.05[82] | 0.75[83] | 1.05[84] |
13 | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha | [85] | 1.36[86] | 1.51[87] | 2.74[88] | 2.55[89] | 2.43[90] | 3.54[91] |
14 | SOS1 | Son of sevenless homolog 1 | [92] | 1.73[93] | 3.29[94] | 2.94[95] | 1.33[96] | 0.94[97] | 1.08[98] |
15 | PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta | [99] | 3.71[100] | 3.96[101] | 4.71[102] | 1.19[103] | 2.13[104] | 0.25[105] |
16 | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | 5.33[106] | 4.97[107] | 4.44[108] | 3.31[109] | 3.17[110] | 0.88[111] | |
17 | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 3.05[112] | 3.58[113] | 3.88[114] | 1.54[115] | 2.07[116] | 1.69[117] | |
18 | FYN | Tyrosine-protein kinase Fyn | [118] | 2.78[119] | -5.79[120] | 2.91[121] | 1.96[122] | 3.86[123] | 1.51[124] |
19 | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 1.45[125] | 3.12[126] | 3.45[127] | 1.61[128] | 2.19[129] | 2.45[130] | |
20 | KLRD1 | Natural killer cells antigen CD94 | [131] | -1.15[132] | -0.04[133] | 0.25[134] | -1.07[135] | -0.95[136] | 0.65[137] |
21 | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | 0.55[138] | -5.16[139] | 2.42[140] | -2.25[141] | -0.72[142] | 3.25[143] | |
22 | LCP2 | Lymphocyte cytosolic protein 2 | [144] | [145] | [146] | [147] | -3.23[148] | [149] | 1.68[150] |
23 | LAT | Linker for activation of T-cells family member 1 | [151] | 0.39[152] | 1.95[153] | 0.49[154] | -0.88[155] | 0.07[156] | 0.12[157] |
24 | CD300E | CMRF35-like molecule 2 | [158] | -6.19[159] | -4.00[160] | -5.44[161] | -7.32[162] | -6.29[163] | -0.70[164] |
25 | VAV3 | Guanine nucleotide exchange factor VAV3 | [165] | 3.64[166] | 1.96[167] | 4.27[168] | 4.17[169] | -1.43[170] | 1.89[171] |
26 | KLRK1 | NKG2-D type II integral membrane protein | [172] | [173] | [174] | [175] | -5.82[176] | [177] | -3.31[178] |
27 | SIRPB1 | Signal-regulatory protein beta-1 | [179] | -1.23[180] | -4.11[181] | 1.01[182] | -1.37[183] | -1.52[184] | 0.52[185] |
28 | LCK | Tyrosine-protein kinase Lck | [186] | 4.61[187] | 4.72[188] | -5.14[189] | -4.60[190] | -4.43[191] | 1.77[192] |
29 | SYK | Tyrosine-protein kinase SYK | [193] | -6.33[194] | -0.43[195] | -3.31[196] | 0.59[197] | -2.56[198] | 3.90[199] |
30 | BTK | Tyrosine-protein kinase BTK | [200] | -5.55[201] | [202] | 1.46[203] | -2.52[204] | -4.38[205] | 2.37[206] |
31 | CD300LB | CMRF35-like molecule 7 | [207] | [208] | [209] | [210] | -4.85[211] | [212] | -1.23[213] |
32 | SIGLEC15 | Sialic acid-binding Ig-like lectin 15 | [214] | -0.66[215] | [216] | [217] | -1.37[218] | -3.96[219] | -0.34[220] |
33 | SIGLEC14 | Sialic acid-binding Ig-like lectin 14 | [221] | 1.86[222] | -0.11[223] | -1.19[224] | -3.61[225] | -2.35[226] | 2.27[227] |
34 | TREM2 | Triggering receptor expressed on myeloid cells 2 | [228] | 3.71[229] | 0.05[230] | [231] | -5.30[232] | -1.66[233] | 0.24[234] |
35 | GRAP2 | GRB2-related adapter protein 2 | [235] | -4.01[236] | [237] | -0.23[238] | -1.49[239] | -0.08[240] | 1.38[241] |
36 | TREM1 | Triggering receptor expressed on myeloid cells 1 | [242] | 3.34[243] | -0.88[244] | [245] | -0.23[246] | 4.16[247] | 1.44[248] |
37 | CLEC5A | C-type lectin domain family 5 member A | [249] | [250] | -1.99[251] | 1.09[252] | [253] | [254] | 1.13[255] |
38 | KIR2DS4 | Killer cell immunoglobulin-like receptor 2DS4 | [256] | [257] | [258] | [259] | [260] | [261] | -0.71[262] |
39 | KLRC2 | NKG2-C type II integral membrane protein | [263] | [264] | [265] | [266] | [267] | [268] | [269] |
40 | KIR2DS2 | Killer cell immunoglobulin-like receptor 2DS2 | [270] | [271] | [272] | [273] | [274] | [275] | [276] |
41 | KIR2DS1 | Killer cell immunoglobulin-like receptor 2DS1 | [277] | [278] | [279] | [280] | [281] | [282] | [283] |
42 | KIR3DS1 | Killer cell immunoglobulin-like receptor 3DS1 | [284] | [285] | [286] | [287] | [288] | [289] | [290] |
43 | KIR2DS5 | Killer cell immunoglobulin-like receptor 2DS5 | [291] | [292] | [293] | [294] | [295] | [296] | [297] |
44 | NCR2 | Natural cytotoxicity triggering receptor 2 | [298] | [299] | [300] | [301] | [302] | [303] | [304] |