REACTOME_CYTOSOLIC_SULFONATION_OF_SMALL_MOLECULES Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 SULT2A1 Bile salt sulfotransferase [1] -1.73[2] -1.20[3] -1.75[4] -10.52[5] -10.24[6] 0.27[7]
2 SULT1A1 Sulfotransferase 1A1 [8] 0.04[9] 0.28[10] -2.48[11] -1.51[12] -1.35[13] -2.18[14]
3 ABHD14B Protein ABHD14B [15] 0.70[16] 0.55[17] 0.13[18] -0.36[19] 0.38[20] -0.04[21]
4 TPST2 Protein-tyrosine sulfotransferase 2 [22] -0.88[23] -1.18[24] 0.12[25] 0.75[26] -0.92[27] 0.48[28]
5 PAPSS2 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 [29] -4.10[30] -6.42[31] 1.53[32] 1.95[33] 2.47[34] 1.49[35]
6 SULT1A2 Sulfotransferase 1A2 [36] -0.01[37] 0.28[38] -3.77[39] -1.35[40] -4.51[41] -2.01[42]
7 TPST1 Protein-tyrosine sulfotransferase 1 [43] -0.20[44] 0.03[45] 1.13[46] 1.52[47] 1.26[48] 0.11[49]
8 PAPSS1 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [50] 2.27[51] 2.33[52] 2.32[53] 2.29[54] 2.46[55] -1.52[56]
9 SULT1A3 Sulfotransferase 1A3 [57] [58] [59] [60] [61] [62] [63]
10 SULT1A4 Sulfotransferase 1A4 [64] [65] [66] [67] [68] [69] [70]
11 SLC35B2 Adenosine 3'-phospho 5'-phosphosulfate transporter 1 [71] 3.27[72] 3.02[73] 2.00[74] 3.51[75] 3.10[76] -0.05[77]
12 SLC35B3 Adenosine 3'-phospho 5'-phosphosulfate transporter 2 [78] 1.04[79] 1.13[80] 1.55[81] 2.03[82] 1.50[83] -0.12[84]
13 BPNT1 3'(2'),5'-bisphosphate nucleotidase 1 [85] 2.41[86] 2.56[87] 3.82[88] 3.37[89] 2.14[90] -0.21[91]
14 SULT1E1 Estrogen sulfotransferase [92] -1.31[93] 0.95[94] 2.14[95] -6.11[96] 2.69[97] 1.06[98]
15 SLC26A1 Sulfate anion transporter 1 [99] 2.00[100] 2.12[101] 2.90[102] 1.10[103] -0.46[104] 2.16[105]
16 SULT1C2 Sulfotransferase 1C2 [106] 0.21[107] -0.16[108] 0.66[109] 0.89[110] -4.20[111] -2.73[112]
17 PODXL2 Podocalyxin-like protein 2 [113] 5.03[114] -1.27[115] 5.08[116] 3.87[117] 0.82[118] -2.68[119]
18 SLC26A2 Sulfate transporter [120] 2.84[121] 2.80[122] 3.22[123] 4.73[124] 6.09[125] 0.99[126]
19 SULT1B1 Sulfotransferase family cytosolic 1B member 1 [127] -3.32[128] -2.41[129] -2.51[130] [131] 0.44[132] 2.93[133]
20 SULT1C4 Sulfotransferase 1C4 [134] 2.41[135] 1.93[136] 1.48[137] -5.25[138] -5.13[139] 0.61[140]
21 SULT4A1 Sulfotransferase 4A1 [141] 1.67[142] [143] [144] [145] 7.89[146] 0.11[147]
22 SULT6B1 Sulfotransferase 6B1 [148] [149] [150] [151] [152] [153] [154]
23 BPNT2 [155] [156] [157] [158] [159] [160] [161]
24 SULT2B1 Sulfotransferase family cytosolic 2B member 1 [162] [163] [164] [165] [166] [167] [168]
[1]
ref_hepatocyte SULT2A1
Mean 281
Standard deviation 2.8e+02
Values 4.5e+02 5.2 7.2 6.4e+02 3e+02
[2]
HepG2 SULT2A1
Mean 64.4
Standard deviation 29
Values 44 85
[3]
HepG2.C3A SULT2A1
Mean 109
Standard deviation 37
Values 1.4e+02 83
[4]
HuH.7 SULT2A1
Mean 43.5
Standard deviation 18
Values 29 64 38
[5]
SNU475 SULT2A1
Mean 0.0827
Standard deviation 0.012
Values 0.074 0.091
[6]
THLE SULT2A1
Mean 0.106
Standard deviation 0.0079
Values 0.1 0.11
[7]
liver SULT2A1
Mean 489
Standard deviation 2.7e+02
Values 8.1e+02 2.9e+02 6.3e+02 2.3e+02
[8]
ref_hepatocyte SULT1A1
Mean 97.6
Standard deviation 1.2e+02
Values 27 33 6 1.2e+02 3e+02
[9]
HepG2 SULT1A1
Mean 76.1
Standard deviation 9
Values 82 70
[10]
HepG2.C3A SULT1A1
Mean 105
Standard deviation 7.6
Values 1.1e+02 1e+02
[11]
HuH.7 SULT1A1
Mean 9.1
Standard deviation 2.4
Values 8.9 6.8 12
[12]
SNU475 SULT1A1
Mean 14.8
Standard deviation 8.6
Values 21 8.8
[13]
THLE SULT1A1
Mean 17.4
Standard deviation 0.098
Values 17 17
[14]
liver SULT1A1
Mean 31.2
Standard deviation 17
Values 44 16 47 17
[15]
ref_hepatocyte ABHD14B
Mean 31.3
Standard deviation 30
Values 7.2 5.4 19 52 73
[16]
HepG2 ABHD14B
Mean 38.5
Standard deviation 4.8
Values 42 35
[17]
HepG2.C3A ABHD14B
Mean 40.7
Standard deviation 5.1
Values 44 37
[18]
HuH.7 ABHD14B
Mean 17.8
Standard deviation 2.6
Values 19 15 19
[19]
SNU475 ABHD14B
Mean 10.6
Standard deviation 0.64
Values 11 10
[20]
THLE ABHD14B
Mean 18.5
Standard deviation 1.3
Values 19 18
[21]
liver ABHD14B
Mean 44.2
Standard deviation 37
Values 68 13 82 13
[22]
ref_hepatocyte TPST2
Mean 23.9
Standard deviation 15
Values 10 20 12 46 31
[23]
HepG2 TPST2
Mean 9.86
Standard deviation 0.75
Values 10 9.3
[24]
HepG2.C3A TPST2
Mean 9.33
Standard deviation 2.1
Values 11 7.9
[25]
HuH.7 TPST2
Mean 13.5
Standard deviation 8.4
Values 8.1 23 9.3
[26]
SNU475 TPST2
Mean 17.4
Standard deviation 0.3
Values 18 17
[27]
THLE TPST2
Mean 5.73
Standard deviation 0.43
Values 5.4 6
[28]
liver TPST2
Mean 48.3
Standard deviation 14
Values 70 40 42 42
[29]
ref_hepatocyte PAPSS2
Mean 21.5
Standard deviation 20
Values 0.061 46 5.9 19 36
[30]
HepG2 PAPSS2
Mean 0.947
Standard deviation 0.24
Values 0.78 1.1
[31]
HepG2.C3A PAPSS2
Mean 0.223
Standard deviation 0.11
Values 0.15 0.3
[32]
HuH.7 PAPSS2
Mean 32.5
Standard deviation 12
Values 28 46 24
[33]
SNU475 PAPSS2
Mean 36
Standard deviation 1.8
Values 35 37
[34]
THLE PAPSS2
Mean 54.1
Standard deviation 10
Values 47 61
[35]
liver PAPSS2
Mean 87.1
Standard deviation 22
Values 1e+02 68 1.1e+02 69
[36]
ref_hepatocyte SULT1A2
Mean 21.1
Standard deviation 23
Values 12 2.7 1.9 31 57
[37]
HepG2 SULT1A2
Mean 15.9
Standard deviation 1.6
Values 17 15
[38]
HepG2.C3A SULT1A2
Mean 22.8
Standard deviation 0.54
Values 23 22
[39]
HuH.7 SULT1A2
Mean 0.807
Standard deviation 0.37
Values 0.88 0.41 1.1
[40]
SNU475 SULT1A2
Mean 3.57
Standard deviation 2
Values 5 2.2
[41]
THLE SULT1A2
Mean 0.42
Standard deviation 0.067
Values 0.47 0.37
[42]
liver SULT1A2
Mean 7.59
Standard deviation 8.1
Values 4 3 20 3.7
[43]
ref_hepatocyte TPST1
Mean 14.3
Standard deviation 9.2
Values 7.6 9.4 6.7 27 20
[44]
HepG2 TPST1
Mean 9.42
Standard deviation 1.2
Values 8.6 10
[45]
HepG2.C3A TPST1
Mean 12.9
Standard deviation 3
Values 15 11
[46]
HuH.7 TPST1
Mean 16.3
Standard deviation 2.2
Values 14 18 17
[47]
SNU475 TPST1
Mean 17.7
Standard deviation 2.8
Values 16 20
[48]
THLE TPST1
Mean 15.6
Standard deviation 0.81
Values 15 16
[49]
liver TPST1
Mean 22.4
Standard deviation 3.1
Values 22 21 27 20
[50]
ref_hepatocyte PAPSS1
Mean 11.8
Standard deviation 18
Values 43 8.1 3.4 1.9 2.5
[51]
HepG2 PAPSS1
Mean 43
Standard deviation 11
Values 35 51
[52]
HepG2.C3A PAPSS1
Mean 52.7
Standard deviation 0.024
Values 53 53
[53]
HuH.7 PAPSS1
Mean 30.6
Standard deviation 3.2
Values 32 27 33
[54]
SNU475 PAPSS1
Mean 24.8
Standard deviation 9.8
Values 32 18
[55]
THLE PAPSS1
Mean 29.5
Standard deviation 0.55
Values 30 29
[56]
liver PAPSS1
Mean 5.95
Standard deviation 2
Values 7 6.1 7.7 3.1
[57]
ref_hepatocyte SULT1A3
Mean 9.88
Standard deviation 12
Values 29 2.2 0.44 8.2 9.2
[58]
HepG2 SULT1A3
Missing
[59]
HepG2.C3A SULT1A3
Missing
[60]
HuH.7 SULT1A3
Missing
[61]
SNU475 SULT1A3
Missing
[62]
THLE SULT1A3
Missing
[63]
liver SULT1A3
Missing
[64]
ref_hepatocyte SULT1A4
Mean 9.88
Standard deviation 12
Values 29 2.2 0.44 8.2 9.2
[65]
HepG2 SULT1A4
Missing
[66]
HepG2.C3A SULT1A4
Missing
[67]
HuH.7 SULT1A4
Missing
[68]
SNU475 SULT1A4
Missing
[69]
THLE SULT1A4
Missing
[70]
liver SULT1A4
Missing
[71]
ref_hepatocyte SLC35B2
Mean 9.86
Standard deviation 3.7
Values 6 7.3 15 12 8.7
[72]
HepG2 SLC35B2
Mean 72
Standard deviation 1.7
Values 73 71
[73]
HepG2.C3A SLC35B2
Mean 70.9
Standard deviation 1.7
Values 70 72
[74]
HuH.7 SLC35B2
Mean 20.6
Standard deviation 4.7
Values 21 16 25
[75]
SNU475 SLC35B2
Mean 48.6
Standard deviation 7.8
Values 54 43
[76]
THLE SLC35B2
Mean 38.5
Standard deviation 6
Values 34 43
[77]
liver SLC35B2
Mean 13.8
Standard deviation 6.3
Values 19 8.8 20 8
[78]
ref_hepatocyte SLC35B3
Mean 6.11
Standard deviation 4.3
Values 3.7 4.3 1.2 10 11
[79]
HepG2 SLC35B3
Mean 9.55
Standard deviation 4.5
Values 6.3 13
[80]
HepG2.C3A SLC35B3
Mean 11.8
Standard deviation 1.6
Values 11 13
[81]
HuH.7 SLC35B3
Mean 9.35
Standard deviation 0.56
Values 9.7 8.7 9.7
[82]
SNU475 SLC35B3
Mean 10.8
Standard deviation 3.8
Values 13 8.1
[83]
THLE SLC35B3
Mean 7.85
Standard deviation 0.9
Values 7.2 8.5
[84]
liver SLC35B3
Mean 8.16
Standard deviation 2.7
Values 11 6.8 9.7 5.1
[85]
ref_hepatocyte BPNT1
Mean 6.09
Standard deviation 2.1
Values 8.3 5.8 2.6 6.9 6.8
[86]
HepG2 BPNT1
Mean 24.5
Standard deviation 1.2
Values 24 25
[87]
HepG2.C3A BPNT1
Mean 31.8
Standard deviation 8.9
Values 25 38
[88]
HuH.7 BPNT1
Mean 44.9
Standard deviation 4.4
Values 45 40 49
[89]
SNU475 BPNT1
Mean 27.1
Standard deviation 6.8
Values 32 22
[90]
THLE BPNT1
Mean 12.2
Standard deviation 1.2
Values 11 13
[91]
liver BPNT1
Mean 7.63
Standard deviation 1.6
Values 9.6 8 7.2 5.8
[92]
ref_hepatocyte SULT1E1
Mean 2.69
Standard deviation 3.5
Values 0.8 0.67 0.15 3.3 8.5
[93]
HepG2 SULT1E1
Mean 0.821
Standard deviation 0.16
Values 0.71 0.93
[94]
HepG2.C3A SULT1E1
Mean 4.62
Standard deviation 1.2
Values 3.8 5.5
[95]
HuH.7 SULT1E1
Mean 6.19
Standard deviation 1.8
Values 4.4 7.9 6.3
[96]
SNU475 SULT1E1
Mean 0.0169
Standard deviation 0.0024
Values 0.019 0.015
[97]
THLE SULT1E1
Mean 7.92
Standard deviation 1.1
Values 7.1 8.7
[98]
liver SULT1E1
Mean 8.11
Standard deviation 8.7
Values 21 2.4 4.2 4.8
[99]
ref_hepatocyte SLC26A1
Mean 2.52
Standard deviation 1.6
Values 2.3 0.24 1.9 4.5 3.6
[100]
HepG2 SLC26A1
Mean 7.65
Standard deviation 0.6
Values 7.2 8.1
[101]
HepG2.C3A SLC26A1
Mean 9.73
Standard deviation 0.68
Values 10 9.2
[102]
HuH.7 SLC26A1
Mean 9.84
Standard deviation 2.5
Values 8.8 13 8.1
[103]
SNU475 SLC26A1
Mean 2.34
Standard deviation 0.017
Values 2.3 2.4
[104]
THLE SLC26A1
Mean 0.835
Standard deviation 0.21
Values 0.69 0.98
[105]
liver SLC26A1
Mean 16.3
Standard deviation 14
Values 4.8 25 4.9 31
[106]
ref_hepatocyte SULT1C2
Mean 1.62
Standard deviation 3.1
Values 7.1 0.21 0.24 0.35 0.16
[107]
HepG2 SULT1C2
Mean 1.43
Standard deviation 0.5
Values 1.1 1.8
[108]
HepG2.C3A SULT1C2
Mean 1.29
Standard deviation 0.36
Values 1 1.5
[109]
HuH.7 SULT1C2
Mean 1.33
Standard deviation 0.91
Values 0.75 2.4 0.87
[110]
SNU475 SULT1C2
Mean 1.3
Standard deviation 0.89
Values 1.9 0.67
[111]
THLE SULT1C2
Mean 0.0402
Standard deviation 0.027
Values 0.059 0.021
[112]
liver SULT1C2
Mean 0.355
Standard deviation 0.33
Values 0.047 0.71 0.57 0.093
[113]
ref_hepatocyte PODXL2
Mean 1.46
Standard deviation 0.88
Values 2.9 0.76 1.2 0.84 1.6
[114]
HepG2 PODXL2
Mean 36.3
Standard deviation 5.3
Values 40 33
[115]
HepG2.C3A PODXL2
Mean 0.536
Standard deviation 0.03
Values 0.52 0.56
[116]
HuH.7 PODXL2
Mean 25.8
Standard deviation 9.7
Values 29 15 33
[117]
SNU475 PODXL2
Mean 9.25
Standard deviation 1.7
Values 8.1 10
[118]
THLE PODXL2
Mean 1.17
Standard deviation 0.19
Values 1 1.3
[119]
liver PODXL2
Mean 0.331
Standard deviation 0.14
Values 0.49 0.37 0.15 0.3
[120]
ref_hepatocyte SLC26A2
Mean 1.34
Standard deviation 1.5
Values 3.4 2.5 0.4 0.17 0.2
[121]
HepG2 SLC26A2
Mean 7.24
Standard deviation 4.3
Values 4.2 10
[122]
HepG2.C3A SLC26A2
Mean 8.25
Standard deviation 1.2
Values 7.4 9.1
[123]
HuH.7 SLC26A2
Mean 6.52
Standard deviation 1.1
Values 7.2 7.2 5.2
[124]
SNU475 SLC26A2
Mean 15.3
Standard deviation 3.6
Values 18 13
[125]
THLE SLC26A2
Mean 41.5
Standard deviation 10
Values 34 49
[126]
liver SLC26A2
Mean 3.85
Standard deviation 1.8
Values 1.7 6 3.7 4.1
[127]
ref_hepatocyte SULT1B1
Mean 0.754
Standard deviation 1.2
Values 0 0 0 2.8 0.93
[128]
HepG2 SULT1B1
Mean 0.0573
Standard deviation 0.0082
Values 0.063 0.051
[129]
HepG2.C3A SULT1B1
Mean 0.126
Standard deviation 0.095
Values 0.058 0.19
[130]
HuH.7 SULT1B1
Mean 0.069
Standard deviation 0.054
Values 0.082 0.12 0.0094
[131]
SNU475 SULT1B1
Mean 0
Standard deviation 0
Values 0 0
[132]
THLE SULT1B1
Mean 0.465
Standard deviation 0.15
Values 0.36 0.57
[133]
liver SULT1B1
Mean 8.32
Standard deviation 2.2
Values 7.9 11 5.9 8.2
[134]
ref_hepatocyte SULT1C4
Mean 0.205
Standard deviation 0.33
Values 0.78 0.073 0 0.17 0
[135]
HepG2 SULT1C4
Mean 0.826
Standard deviation 0.23
Values 0.99 0.66
[136]
HepG2.C3A SULT1C4
Mean 0.693
Standard deviation 0.16
Values 0.81 0.58
[137]
HuH.7 SULT1C4
Mean 0.298
Standard deviation 0.38
Values 0.041 0.73 0.12
[138]
SNU475 SULT1C4
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[139]
THLE SULT1C4
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[140]
liver SULT1C4
Mean 0.452
Standard deviation 0.12
Values 0.49 0.46 0.57 0.29
[141]
ref_hepatocyte SULT4A1
Mean 0.0065
Standard deviation 0.015
Values 0 0 0 0 0.033
[142]
HepG2 SULT4A1
Mean 0.0157
Standard deviation 0.014
Values 0.0057 0.026
[143]
HepG2.C3A SULT4A1
Mean 0
Standard deviation 0
Values 0 0
[144]
HuH.7 SULT4A1
Mean 0
Standard deviation 0
Values 0 0 0
[145]
SNU475 SULT4A1
Mean 0
Standard deviation 0
Values 0 0
[146]
THLE SULT4A1
Mean 0.7
Standard deviation 0.0029
Values 0.7 0.7
[147]
liver SULT4A1
Mean 0.0102
Standard deviation 0.013
Values 0 0.014 0 0.026
[148]
ref_hepatocyte SULT6B1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[149]
HepG2 SULT6B1
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[150]
HepG2.C3A SULT6B1
Mean 0.0215
Standard deviation 0.03
Values 0 0.043
[151]
HuH.7 SULT6B1
Mean 0
Standard deviation 0
Values 0 0 0
[152]
SNU475 SULT6B1
Mean 0.0125
Standard deviation 0.011
Values 0.0046 0.02
[153]
THLE SULT6B1
Mean 0
Standard deviation 0
Values 0 0
[154]
liver SULT6B1
Mean 0
Standard deviation 0
Values 0 0 0 0
[155]
ref_hepatocyte BPNT2
Missing
[156]
HepG2 BPNT2
Missing
[157]
HepG2.C3A BPNT2
Missing
[158]
HuH.7 BPNT2
Missing
[159]
SNU475 BPNT2
Missing
[160]
THLE BPNT2
Missing
[161]
liver BPNT2
Missing
[162]
ref_hepatocyte SULT2B1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[163]
HepG2 SULT2B1
Mean 2.26
Standard deviation 1.3
Values 3.2 1.3
[164]
HepG2.C3A SULT2B1
Mean 0.0468
Standard deviation 0.025
Values 0.029 0.064
[165]
HuH.7 SULT2B1
Mean 0.407
Standard deviation 0.08
Values 0.34 0.38 0.5
[166]
SNU475 SULT2B1
Mean 0.303
Standard deviation 0.21
Values 0.45 0.15
[167]
THLE SULT2B1
Mean 0.0142
Standard deviation 0.005
Values 0.018 0.011
[168]
liver SULT2B1
Mean 0.0309
Standard deviation 0.027
Values 0.071 0.014 0.026 0.013