REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CYP2E1 Cytochrome P450 2E1 [1] -11.00[2] -11.23[3] -7.64[4] -11.84[5] -10.52[6] -0.81[7]
2 CYP2C8 Cytochrome P450 2C8 [8] -13.00[9] -8.35[10] -5.80[11] -8.92[12] [13] 0.11[14]
3 CYP2C9 Cytochrome P450 2C9 [15] [16] -13.27[17] -6.02[18] -11.61[19] -11.05[20] 0.61[21]
4 CYP3A4 Cytochrome P450 3A4 [22] -8.25[23] -8.46[24] -9.83[25] -11.92[26] -10.62[27] 0.33[28]
5 CYP2A6 Cytochrome P450 2A6 [29] -14.37[30] [31] -6.26[32] -8.68[33] -11.36[34] -2.02[35]
6 CYP3A5 Cytochrome P450 3A5 [36] -3.32[37] -1.18[38] -3.58[39] -4.50[40] -6.95[41] 0.69[42]
7 CYP27A1 Sterol 26-hydroxylase, mitochondrial [43] 1.41[44] 2.11[45] -0.63[46] 0.04[47] -1.76[48] -0.32[49]
8 CYP4A11 Cytochrome P450 4A11 [50] -11.17[51] -8.63[52] -10.15[53] -7.74[54] -9.00[55] 0.47[56]
9 POR NADPH--cytochrome P450 reductase [57] 2.57[58] 3.06[59] 2.18[60] 2.82[61] 1.55[62] 0.96[63]
10 CYP1A2 Cytochrome P450 1A2 [64] -7.43[65] -6.22[66] -6.53[67] -5.49[68] -6.15[69] -2.06[70]
11 CYP51A1 Lanosterol 14-alpha demethylase [71] 0.78[72] 3.10[73] 3.38[74] 2.16[75] 1.58[76] 0.40[77]
12 CYP2B6 Cytochrome P450 2B6 [78] -6.15[79] -2.80[80] -1.08[81] -6.48[82] -7.72[83] 1.99[84]
13 CYP1A1 Cytochrome P450 1A1 [85] -0.97[86] -2.65[87] 1.36[88] -0.89[89] -1.68[90] -6.20[91]
14 CYP2C18 Cytochrome P450 2C18 [92] -7.97[93] -9.54[94] -3.34[95] -8.75[96] -7.06[97] -0.86[98]
15 CYP2D6 Cytochrome P450 2D6 [99] -4.41[100] -2.02[101] -4.20[102] -4.99[103] -5.75[104] 0.82[105]
16 CYP8B1 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase [106] -4.73[107] -2.27[108] -5.85[109] -5.38[110] -7.46[111] 2.05[112]
17 CYP4F2 Phylloquinone omega-hydroxylase CYP4F2 [113] -3.13[114] 0.40[115] -10.95[116] -8.95[117] -7.31[118] 0.41[119]
18 CYP3A7 Cytochrome P450 3A7 [120] -3.43[121] -1.25[122] -5.63[123] [124] -8.42[125] -2.08[126]
19 CYP2J2 Cytochrome P450 2J2 [127] -1.91[128] -1.99[129] 1.47[130] -3.59[131] -2.36[132] -0.13[133]
20 NR1H4 Bile acid receptor [134] 1.90[135] 2.40[136] 4.53[137] -3.46[138] -3.73[139] 0.12[140]
21 CYP2C19 Cytochrome P450 2C19 [141] [142] [143] -3.16[144] -9.30[145] -9.35[146] 1.17[147]
22 CYP2A7 Cytochrome P450 2A7 [148] [149] [150] -1.67[151] -7.28[152] [153] -2.17[154]
23 CYP4F11 Phylloquinone omega-hydroxylase CYP4F11 [155] 0.96[156] 0.45[157] -6.49[158] 3.48[159] -6.81[160] 0.34[161]
24 RXRA Retinoic acid receptor RXR-alpha [162] 3.44[163] 3.15[164] 4.34[165] 4.60[166] 4.03[167] 1.74[168]
25 CYP4F3 Docosahexaenoic acid omega-hydroxylase CYP4F3 [169] 0.03[170] 0.86[171] 2.48[172] 0.08[173] -6.31[174] 1.78[175]
26 FDX1 Adrenodoxin, mitochondrial [176] 2.79[177] 2.27[178] 1.09[179] 4.30[180] 3.98[181] 0.40[182]
27 CYP4V2 Cytochrome P450 4V2 [183] 0.25[184] 1.91[185] 0.32[186] 0.72[187] 1.02[188] 1.35[189]
28 CYP4F12 Cytochrome P450 4F12 [190] 0.79[191] 2.04[192] 3.57[193] -0.35[194] -4.64[195] -0.21[196]
29 FDXR NADPH:adrenodoxin oxidoreductase, mitochondrial [197] 6.10[198] 5.34[199] 2.54[200] 2.70[201] 3.54[202] -2.32[203]
30 CYP39A1 24-hydroxycholesterol 7-alpha-hydroxylase [204] -1.57[205] -1.84[206] 3.15[207] -0.34[208] 1.37[209] 0.07[210]
31 ARNT Aryl hydrocarbon receptor nuclear translocator [211] 3.91[212] 3.61[213] 4.83[214] 5.96[215] 5.49[216] 1.13[217]
32 CYP21A2 Steroid 21-hydroxylase [218] -2.37[219] -0.53[220] -4.55[221] 0.36[222] -5.19[223] -0.68[224]
33 AHR Aryl hydrocarbon receptor [225] 4.61[226] 4.83[227] 6.19[228] 5.14[229] 5.81[230] 2.19[231]
34 CYP7A1 Cholesterol 7-alpha-monooxygenase [232] -0.85[233] -3.27[234] -6.45[235] -5.38[236] [237] -3.36[238]
35 CYP4A22 Cytochrome P450 4A22 [239] [240] [241] [242] [243] [244] 1.86[245]
36 CYP2R1 Vitamin D 25-hydroxylase [246] -0.49[247] 1.22[248] 3.78[249] 3.27[250] 2.52[251] -1.28[252]
37 CYP4F22 Cytochrome P450 4F22 [253] -2.39[254] [255] -7.13[256] -5.37[257] -3.80[258] -1.38[259]
38 CYP1B1 Cytochrome P450 1B1 [260] -3.56[261] -3.08[262] 1.38[263] 6.10[264] 8.46[265] 0.61[266]
39 NCOA1 Nuclear receptor coactivator 1 [267] 3.96[268] 4.44[269] 4.98[270] 6.38[271] 5.60[272] 2.25[273]
40 CYP3A43 Cytochrome P450 3A43 [274] -1.36[275] 1.44[276] 1.61[277] [278] -5.79[279] 0.98[280]
41 CYP7B1 25-hydroxycholesterol 7-alpha-hydroxylase [281] -4.54[282] -3.34[283] [284] -4.43[285] -0.95[286] 1.87[287]
42 NCOA2 Nuclear receptor coactivator 2 [288] 5.07[289] 5.80[290] 7.98[291] 7.79[292] 5.85[293] 4.20[294]
43 CYP19A1 Aromatase [295] 5.42[296] 6.36[297] 0.25[298] 2.94[299] 0.25[300] -6.74[301]
44 CYP2U1 Cytochrome P450 2U1 [302] 3.67[303] -0.22[304] 0.33[305] 5.82[306] 6.37[307] 1.67[308]
45 POMC Pro-opiomelanocortin [309] [310] -4.96[311] [312] [313] -2.77[314] -2.60[315]
46 TBXAS1 Thromboxane-A synthase [316] 0.52[317] 2.50[318] -0.35[319] 5.23[320] 3.54[321] 1.25[322]
47 CYP11A1 Cholesterol side-chain cleavage enzyme, mitochondrial [323] 2.83[324] 0.23[325] [326] 1.33[327] 5.14[328] 0.07[329]
48 CYP2W1 Cytochrome P450 2W1 [330] 7.19[331] 9.01[332] 3.27[333] 1.16[334] 0.51[335] -4.43[336]
49 CYP2S1 Cytochrome P450 2S1 [337] 6.40[338] 5.19[339] 4.72[340] 5.77[341] 5.61[342] -1.05[343]
50 CYP24A1 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial [344] 11.63[345] 6.68[346] 1.39[347] 8.70[348] 1.65[349] -7.50[350]
51 CYP26A1 Cytochrome P450 26A1 [351] 6.66[352] 0.74[353] 4.63[354] 4.74[355] -1.19[356] 0.60[357]
52 PTGIS Prostacyclin synthase [358] 1.93[359] 2.97[360] 7.29[361] 5.71[362] 11.42[363] 4.44[364]
53 AHRR Aryl hydrocarbon receptor repressor [365] 4.88[366] 3.91[367] 4.56[368] 9.38[369] 7.53[370] 0.33[371]
54 CYP2A13 Cytochrome P450 2A13 [372] [373] [374] [375] [376] [377] -0.92[378]
55 CYP27B1 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial [379] 6.17[380] 7.52[381] 7.26[382] 5.78[383] 6.28[384] 1.27[385]
56 CYP46A1 Cholesterol 24-hydroxylase [386] -0.30[387] 0.96[388] 0.28[389] 2.03[390] 2.99[391] 1.85[392]
57 CYP2F1 Cytochrome P450 2F1 [393] 2.72[394] 1.01[395] 5.67[396] 6.03[397] 4.68[398] 0.57[399]
58 ARNT2 Aryl hydrocarbon receptor nuclear translocator 2 [400] 8.87[401] 0.79[402] 2.46[403] 11.02[404] 12.54[405] 4.54[406]
59 CYP26B1 Cytochrome P450 26B1 [407] 8.38[408] 5.24[409] 12.80[410] 11.30[411] 10.29[412] 5.13[413]
60 CYP11B2 Cytochrome P450 11B2, mitochondrial [414] [415] [416] [417] [418] [419] [420]
61 CYP11B1 Cytochrome P450 11B1, mitochondrial [421] [422] [423] [424] [425] [426] [427]
62 CYP4B1 Cytochrome P450 4B1 [428] [429] [430] [431] [432] [433] [434]
63 CYP4F8 Cytochrome P450 4F8 [435] [436] [437] [438] [439] [440] [441]
64 PDCD6-AHRR [442] [443] [444] [445] [446] [447] [448]
65 CYP26C1 Cytochrome P450 26C1 [449] [450] [451] [452] [453] [454] [455]
66 FDX2 Ferredoxin-2, mitochondrial [456] [457] [458] [459] [460] [461] [462]
[1]
ref_hepatocyte CYP2E1
Mean 1.39e+03
Standard deviation 1.9e+03
Values 0 4.6 90 2.7e+03 4.1e+03
[2]
HepG2 CYP2E1
Mean 0.133
Standard deviation 0.1
Values 0.21 0.06
[3]
HepG2.C3A CYP2E1
Mean 0.107
Standard deviation 0.15
Values 0.21 0
[4]
HuH.7 CYP2E1
Mean 0.975
Standard deviation 0.29
Values 0.67 1.3 0.99
[5]
SNU475 CYP2E1
Mean 0.0289
Standard deviation 0.005
Values 0.032 0.025
[6]
THLE CYP2E1
Mean 0.0955
Standard deviation 0.082
Values 0.15 0.037
[7]
liver CYP2E1
Mean 1.49e+03
Standard deviation 8.2e+02
Values 2.6e+03 1e+03 1.7e+03 6.9e+02
[8]
ref_hepatocyte CYP2C8
Mean 328
Standard deviation 4.4e+02
Values 0 1.2 19 7.1e+02 9.1e+02
[9]
HepG2 CYP2C8
Mean 0.00788
Standard deviation 0.0051
Values 0.011 0.0043
[10]
HepG2.C3A CYP2C8
Mean 0.186
Standard deviation 0.071
Values 0.14 0.24
[11]
HuH.7 CYP2C8
Mean 0.822
Standard deviation 1
Values 0.16 2 0.3
[12]
SNU475 CYP2C8
Mean 0.0515
Standard deviation 0.02
Values 0.037 0.066
[13]
THLE CYP2C8
Mean 0
Standard deviation 0
Values 0 0
[14]
liver CYP2C8
Mean 666
Standard deviation 3.9e+02
Values 6.8e+02 6.2e+02 1.2e+03 2e+02
[15]
ref_hepatocyte CYP2C9
Mean 285
Standard deviation 4.1e+02
Values 0.064 20 21 4.7e+02 9.2e+02
[16]
HepG2 CYP2C9
Mean 0
Standard deviation 0
Values 0 0
[17]
HepG2.C3A CYP2C9
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[18]
HuH.7 CYP2C9
Mean 0.616
Standard deviation 0.63
Values 0.25 1.3 0.25
[19]
SNU475 CYP2C9
Mean 0.00696
Standard deviation 0.0098
Values 0.014 0
[20]
THLE CYP2C9
Mean 0.0136
Standard deviation 0.011
Values 0.0059 0.021
[21]
liver CYP2C9
Mean 822
Standard deviation 5.3e+02
Values 8.6e+02 6.1e+02 1.5e+03 2.9e+02
[22]
ref_hepatocyte CYP3A4
Mean 259
Standard deviation 4.1e+02
Values 0.24 11 11 3.2e+02 9.6e+02
[23]
HepG2 CYP3A4
Mean 0.167
Standard deviation 0.098
Values 0.097 0.24
[24]
HepG2.C3A CYP3A4
Mean 0.136
Standard deviation 0.096
Values 0.068 0.2
[25]
HuH.7 CYP3A4
Mean 0.0397
Standard deviation 0.029
Values 0.0082 0.064 0.047
[26]
SNU475 CYP3A4
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[27]
THLE CYP3A4
Mean 0.0166
Standard deviation 0.0067
Values 0.012 0.021
[28]
liver CYP3A4
Mean 610
Standard deviation 5.3e+02
Values 4.3e+02 6.4e+02 1.3e+03 49
[29]
ref_hepatocyte CYP2A6
Mean 231
Standard deviation 3e+02
Values 0 4.6 38 5.6e+02 5.5e+02
[30]
HepG2 CYP2A6
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[31]
HepG2.C3A CYP2A6
Mean 0
Standard deviation 0
Values 0 0
[32]
HuH.7 CYP2A6
Mean 0.421
Standard deviation 0.53
Values 0.11 1 0.12
[33]
SNU475 CYP2A6
Mean 0.0428
Standard deviation 0.025
Values 0.06 0.025
[34]
THLE CYP2A6
Mean 0.00887
Standard deviation 0.013
Values 0.018 0
[35]
liver CYP2A6
Mean 107
Standard deviation 1e+02
Values 29 1.8e+02 2.1e+02 13
[36]
ref_hepatocyte CYP3A5
Mean 139
Standard deviation 1.6e+02
Values 22 55 35 2e+02 3.9e+02
[37]
HepG2 CYP3A5
Mean 2.75
Standard deviation 2.1
Values 1.3 4.2
[38]
HepG2.C3A CYP3A5
Mean 11.4
Standard deviation 3.8
Values 14 8.7
[39]
HuH.7 CYP3A5
Mean 1.63
Standard deviation 1.6
Values 0.58 3.5 0.83
[40]
SNU475 CYP3A5
Mean 0.471
Standard deviation 0.12
Values 0.56 0.39
[41]
THLE CYP3A5
Mean 0.113
Standard deviation 0.032
Values 0.14 0.09
[42]
liver CYP3A5
Mean 424
Standard deviation 3.2e+02
Values 9e+02 2.7e+02 2.5e+02 2.8e+02
[43]
ref_hepatocyte CYP27A1
Mean 135
Standard deviation 1.6e+02
Values 62 8 18 2.1e+02 3.7e+02
[44]
HepG2 CYP27A1
Mean 70.5
Standard deviation 16
Values 59 82
[45]
HepG2.C3A CYP27A1
Mean 108
Standard deviation 25
Values 1.3e+02 90
[46]
HuH.7 CYP27A1
Mean 12.2
Standard deviation 7.3
Values 7.2 21 8.9
[47]
SNU475 CYP27A1
Mean 10.5
Standard deviation 1.6
Values 12 9.4
[48]
THLE CYP27A1
Mean 4.01
Standard deviation 0.91
Values 4.7 3.4
[49]
liver CYP27A1
Mean 204
Standard deviation 1e+02
Values 3.3e+02 1.2e+02 2.5e+02 1.1e+02
[50]
ref_hepatocyte CYP4A11
Mean 109
Standard deviation 1.6e+02
Values 0 0 4 2e+02 3.4e+02
[51]
HepG2 CYP4A11
Mean 0.0093
Standard deviation 0.005
Values 0.0057 0.013
[52]
HepG2.C3A CYP4A11
Mean 0.0511
Standard deviation 0.0036
Values 0.049 0.054
[53]
HuH.7 CYP4A11
Mean 0.0135
Standard deviation 0.0098
Values 0.025 0.0064 0.0094
[54]
SNU475 CYP4A11
Mean 0.039
Standard deviation 0.0093
Values 0.032 0.046
[55]
THLE CYP4A11
Mean 0.0216
Standard deviation 0.022
Values 0.0059 0.037
[56]
liver CYP4A11
Mean 286
Standard deviation 2.2e+02
Values 5.7e+02 87 3.6e+02 1.3e+02
[57]
ref_hepatocyte POR
Mean 97
Standard deviation 75
Values 90 32 26 2.1e+02 1.3e+02
[58]
HepG2 POR
Mean 113
Standard deviation 40
Values 1.4e+02 85
[59]
HepG2.C3A POR
Mean 150
Standard deviation 87
Values 2.1e+02 88
[60]
HuH.7 POR
Mean 61.3
Standard deviation 8.5
Values 57 71 56
[61]
SNU475 POR
Mean 52.1
Standard deviation 1.3
Values 51 53
[62]
THLE POR
Mean 28.6
Standard deviation 2.7
Values 27 31
[63]
liver POR
Mean 355
Standard deviation 1.6e+02
Values 2.7e+02 3.2e+02 5.9e+02 2.3e+02
[64]
ref_hepatocyte CYP1A2
Mean 78.9
Standard deviation 1.3e+02
Values 0.4 18 0.97 71 3e+02
[65]
HepG2 CYP1A2
Mean 0.0901
Standard deviation 0.055
Values 0.052 0.13
[66]
HepG2.C3A CYP1A2
Mean 0.197
Standard deviation 0.066
Values 0.24 0.15
[67]
HuH.7 CYP1A2
Mean 0.12
Standard deviation 0.026
Values 0.11 0.1 0.15
[68]
SNU475 CYP1A2
Mean 0.134
Standard deviation 0.091
Values 0.07 0.2
[69]
THLE CYP1A2
Mean 0.112
Standard deviation 0.068
Values 0.16 0.064
[70]
liver CYP1A2
Mean 35.7
Standard deviation 24
Values 55 12 58 19
[71]
ref_hepatocyte CYP51A1
Mean 63
Standard deviation 38
Values 1.2e+02 88 38 27 46
[72]
HepG2 CYP51A1
Mean 21.2
Standard deviation 5.5
Values 17 25
[73]
HepG2.C3A CYP51A1
Mean 99.9
Standard deviation 49
Values 1.3e+02 66
[74]
HuH.7 CYP51A1
Mean 91.5
Standard deviation 23
Values 79 1.2e+02 78
[75]
SNU475 CYP51A1
Mean 21.5
Standard deviation 2.5
Values 23 20
[76]
THLE CYP51A1
Mean 19
Standard deviation 1.2
Values 18 20
[77]
liver CYP51A1
Mean 156
Standard deviation 52
Values 89 1.8e+02 2.1e+02 1.5e+02
[78]
ref_hepatocyte CYP2B6
Mean 49.6
Standard deviation 62
Values 0 4.1 12 1.3e+02 1e+02
[79]
HepG2 CYP2B6
Mean 0.138
Standard deviation 0.15
Values 0.24 0.034
[80]
HepG2.C3A CYP2B6
Mean 1.32
Standard deviation 0.56
Values 1.7 0.92
[81]
HuH.7 CYP2B6
Mean 3.27
Standard deviation 2.3
Values 2.1 5.9 1.9
[82]
SNU475 CYP2B6
Mean 0.0424
Standard deviation 0.04
Values 0.014 0.071
[83]
THLE CYP2B6
Mean 0.0237
Standard deviation 0.033
Values 0.047 0
[84]
liver CYP2B6
Mean 372
Standard deviation 5.3e+02
Values 23 3.2e+02 1.1e+03 7.4
[85]
ref_hepatocyte CYP1A1
Mean 43.8
Standard deviation 36
Values 77 43 0.06 17 82
[86]
HepG2 CYP1A1
Mean 4.39
Standard deviation 2.6
Values 6.2 2.6
[87]
HepG2.C3A CYP1A1
Mean 1.3
Standard deviation 0.1
Values 1.4 1.2
[88]
HuH.7 CYP1A1
Mean 15.8
Standard deviation 1.4
Values 14 17 17
[89]
SNU475 CYP1A1
Mean 1.8
Standard deviation 1.8
Values 0.49 3.1
[90]
THLE CYP1A1
Mean 1.38
Standard deviation 0.04
Values 1.4 1.4
[91]
liver CYP1A1
Mean 1.12
Standard deviation 0.58
Values 1.2 0.47 0.92 1.8
[92]
ref_hepatocyte CYP2C18
Mean 43
Standard deviation 35
Values 0 90 18 51 56
[93]
HepG2 CYP2C18
Mean 0.0336
Standard deviation 0.017
Values 0.046 0.021
[94]
HepG2.C3A CYP2C18
Mean 0.0107
Standard deviation 0.015
Values 0 0.021
[95]
HuH.7 CYP2C18
Mean 0.593
Standard deviation 0.1
Values 0.53 0.71 0.53
[96]
SNU475 CYP2C18
Mean 0.0076
Standard deviation 0.011
Values 0 0.015
[97]
THLE CYP2C18
Mean 0.0325
Standard deviation 0.029
Values 0.012 0.053
[98]
liver CYP2C18
Mean 44.5
Standard deviation 13
Values 36 57 54 31
[99]
ref_hepatocyte CYP2D6
Mean 41.3
Standard deviation 55
Values 0.24 0.47 3.7 1.1e+02 87
[100]
HepG2 CYP2D6
Mean 0.382
Standard deviation 0.03
Values 0.36 0.4
[101]
HepG2.C3A CYP2D6
Mean 1.89
Standard deviation 1
Values 2.6 1.2
[102]
HuH.7 CYP2D6
Mean 0.314
Standard deviation 0.087
Values 0.23 0.4 0.31
[103]
SNU475 CYP2D6
Mean 0.0992
Standard deviation 0.004
Values 0.1 0.096
[104]
THLE CYP2D6
Mean 0.0775
Standard deviation 0.049
Values 0.11 0.043
[105]
liver CYP2D6
Mean 137
Standard deviation 1.2e+02
Values 3.1e+02 53 1.3e+02 57
[106]
ref_hepatocyte CYP8B1
Mean 34.6
Standard deviation 44
Values 1.2 0.33 6.4 79 86
[107]
HepG2 CYP8B1
Mean 0.257
Standard deviation 0.2
Values 0.11 0.4
[108]
HepG2.C3A CYP8B1
Mean 1.33
Standard deviation 0.5
Values 1.7 0.98
[109]
HuH.7 CYP8B1
Mean 0.084
Standard deviation 0.016
Values 0.09 0.096 0.066
[110]
SNU475 CYP8B1
Mean 0.0631
Standard deviation 0.004
Values 0.06 0.066
[111]
THLE CYP8B1
Mean 0.0198
Standard deviation 0.0054
Values 0.024 0.016
[112]
liver CYP8B1
Mean 269
Standard deviation 1.3e+02
Values 4.2e+02 1.3e+02 3e+02 2.2e+02
[113]
ref_hepatocyte CYP4F2
Mean 30.2
Standard deviation 38
Values 1.2 0.054 11 51 87
[114]
HepG2 CYP4F2
Mean 0.677
Standard deviation 0.5
Values 1 0.32
[115]
HepG2.C3A CYP4F2
Mean 7.41
Standard deviation 4.8
Values 11 4
[116]
HuH.7 CYP4F2
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[117]
SNU475 CYP4F2
Mean 0.00464
Standard deviation 0.0066
Values 0.0093 0
[118]
THLE CYP4F2
Mean 0.0192
Standard deviation 0.01
Values 0.012 0.027
[119]
liver CYP4F2
Mean 75.6
Standard deviation 42
Values 86 50 1.3e+02 36
[120]
ref_hepatocyte CYP3A7
Mean 29.1
Standard deviation 41
Values 8.7 0.12 5 1e+02 32
[121]
HepG2 CYP3A7
Mean 0.531
Standard deviation 0.38
Values 0.26 0.8
[122]
HepG2.C3A CYP3A7
Mean 2.26
Standard deviation 0.013
Values 2.3 2.3
[123]
HuH.7 CYP3A7
Mean 0.0822
Standard deviation 0.074
Values 0.033 0.17 0.047
[124]
SNU475 CYP3A7
Mean 0
Standard deviation 0
Values 0 0
[125]
THLE CYP3A7
Mean 0.00858
Standard deviation 0.0046
Values 0.012 0.0053
[126]
liver CYP3A7
Mean 13
Standard deviation 12
Values 30 5.2 11 5.1
[127]
ref_hepatocyte CYP2J2
Mean 23.2
Standard deviation 23
Values 1.9 9.2 9.9 44 51
[128]
HepG2 CYP2J2
Mean 1.21
Standard deviation 0.23
Values 1.4 1
[129]
HepG2.C3A CYP2J2
Mean 1.08
Standard deviation 0.51
Values 1.4 0.72
[130]
HuH.7 CYP2J2
Mean 8.98
Standard deviation 0.32
Values 8.6 9 9.3
[131]
SNU475 CYP2J2
Mean 0.147
Standard deviation 0.13
Values 0.056 0.24
[132]
THLE CYP2J2
Mean 0.454
Standard deviation 0.094
Values 0.52 0.39
[133]
liver CYP2J2
Mean 39.7
Standard deviation 21
Values 66 21 48 24
[134]
ref_hepatocyte NR1H4
Mean 20.8
Standard deviation 17
Values 15 9.3 3.8 43 33
[135]
HepG2 NR1H4
Mean 15.2
Standard deviation 6.4
Values 11 20
[136]
HepG2.C3A NR1H4
Mean 20.3
Standard deviation 1.1
Values 19 21
[137]
HuH.7 NR1H4
Mean 67.4
Standard deviation 13
Values 62 82 58
[138]
SNU475 NR1H4
Mean 0.144
Standard deviation 0.04
Values 0.12 0.17
[139]
THLE NR1H4
Mean 0.158
Standard deviation 0.028
Values 0.18 0.14
[140]
liver NR1H4
Mean 42.4
Standard deviation 11
Values 59 37 35 39
[141]
ref_hepatocyte CYP2C19
Mean 19.2
Standard deviation 30
Values 0 5.9 0 18 72
[142]
HepG2 CYP2C19
Mean 0
Standard deviation 0
Values 0 0
[143]
HepG2.C3A CYP2C19
Mean 0
Standard deviation 0
Values 0 0
[144]
HuH.7 CYP2C19
Mean 0.3
Standard deviation 0.27
Values 0.098 0.6 0.2
[145]
SNU475 CYP2C19
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[146]
THLE CYP2C19
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[147]
liver CYP2C19
Mean 81.4
Standard deviation 39
Values 65 92 1.3e+02 38
[148]
ref_hepatocyte CYP2A7
Mean 15.1
Standard deviation 22
Values 0 0.06 11 52 12
[149]
HepG2 CYP2A7
Mean 0
Standard deviation 0
Values 0 0
[150]
HepG2.C3A CYP2A7
Mean 0
Standard deviation 0
Values 0 0
[151]
HuH.7 CYP2A7
Mean 0.663
Standard deviation 0.76
Values 0.16 1.5 0.3
[152]
SNU475 CYP2A7
Mean 0.00739
Standard deviation 0.0039
Values 0.0046 0.01
[153]
THLE CYP2A7
Mean 0
Standard deviation 0
Values 0 0
[154]
liver CYP2A7
Mean 6.31
Standard deviation 5.5
Values 2 13 9 1.4
[155]
ref_hepatocyte CYP4F11
Mean 14.8
Standard deviation 11
Values 1.7 6.9 14 28 23
[156]
HepG2 CYP4F11
Mean 5.67
Standard deviation 2.2
Values 7.3 4.1
[157]
HepG2.C3A CYP4F11
Mean 3.76
Standard deviation 0.42
Values 4.1 3.5
[158]
HuH.7 CYP4F11
Mean 0.023
Standard deviation 0.029
Values 0 0.013 0.056
[159]
SNU475 CYP4F11
Mean 12.6
Standard deviation 0.65
Values 12 13
[160]
THLE CYP4F11
Mean 0.0133
Standard deviation 0.019
Values 0 0.027
[161]
liver CYP4F11
Mean 35.3
Standard deviation 12
Values 20 46 34 42
[162]
ref_hepatocyte RXRA
Mean 14.5
Standard deviation 6.1
Values 15 7.5 9.4 22 18
[163]
HepG2 RXRA
Mean 30.9
Standard deviation 2.8
Values 33 29
[164]
HepG2.C3A RXRA
Mean 23.9
Standard deviation 6.1
Values 28 20
[165]
HuH.7 RXRA
Mean 41.2
Standard deviation 10
Values 42 51 30
[166]
SNU475 RXRA
Mean 26.9
Standard deviation 8.3
Values 33 21
[167]
THLE RXRA
Mean 23.9
Standard deviation 7.5
Values 19 29
[168]
liver RXRA
Mean 91.4
Standard deviation 37
Values 1.3e+02 72 49 1.2e+02
[169]
ref_hepatocyte CYP4F3
Mean 13.8
Standard deviation 15
Values 3.1 2 2.4 29 33
[170]
HepG2 CYP4F3
Mean 2.77
Standard deviation 0.38
Values 3 2.5
[171]
HepG2.C3A CYP4F3
Mean 4.62
Standard deviation 0.54
Values 5 4.2
[172]
HuH.7 CYP4F3
Mean 10.7
Standard deviation 7.3
Values 7.3 19 5.8
[173]
SNU475 CYP4F3
Mean 1.11
Standard deviation 0.19
Values 1.2 0.97
[174]
THLE CYP4F3
Mean 0.0175
Standard deviation 0.017
Values 0.03 0.0053
[175]
liver CYP4F3
Mean 88.9
Standard deviation 26
Values 68 1.2e+02 95 70
[176]
ref_hepatocyte FDX1
Mean 11.4
Standard deviation 6.1
Values 10 11 2.2 14 19
[177]
HepG2 FDX1
Mean 15.5
Standard deviation 0.65
Values 15 16
[178]
HepG2.C3A FDX1
Mean 10.2
Standard deviation 2.3
Values 8.6 12
[179]
HuH.7 FDX1
Mean 3.41
Standard deviation 0.095
Values 3.3 3.4 3.5
[180]
SNU475 FDX1
Mean 17.1
Standard deviation 1.7
Values 18 16
[181]
THLE FDX1
Mean 18.1
Standard deviation 3.7
Values 15 21
[182]
liver FDX1
Mean 28.4
Standard deviation 18
Values 44 15 44 12
[183]
ref_hepatocyte CYP4V2
Mean 11.2
Standard deviation 14
Values 1.9 3.8 1.4 13 36
[184]
HepG2 CYP4V2
Mean 2.61
Standard deviation 0.57
Values 2.2 3
[185]
HepG2.C3A CYP4V2
Mean 7.77
Standard deviation 2.1
Values 9.2 6.3
[186]
HuH.7 CYP4V2
Mean 1.95
Standard deviation 0.48
Values 1.8 2.5 1.6
[187]
SNU475 CYP4V2
Mean 1.4
Standard deviation 0.069
Values 1.5 1.4
[188]
THLE CYP4V2
Mean 2.28
Standard deviation 0.08
Values 2.3 2.2
[189]
liver CYP4V2
Mean 53.7
Standard deviation 9.2
Values 62 52 41 59
[190]
ref_hepatocyte CYP4F12
Mean 7.85
Standard deviation 7.8
Values 11 0.13 0.73 8.4 19
[191]
HepG2 CYP4F12
Mean 2.67
Standard deviation 0.39
Values 2.9 2.4
[192]
HepG2.C3A CYP4F12
Mean 5.98
Standard deviation 2.1
Values 7.5 4.5
[193]
HuH.7 CYP4F12
Mean 13
Standard deviation 3.4
Values 9.3 16 14
[194]
SNU475 CYP4F12
Mean 0.47
Standard deviation 0.47
Values 0.8 0.14
[195]
THLE CYP4F12
Mean 0.0316
Standard deviation 0.022
Values 0.047 0.016
[196]
liver CYP4F12
Mean 12.8
Standard deviation 14
Values 34 5.3 8.3 3.9
[197]
ref_hepatocyte FDXR
Mean 7.28
Standard deviation 6.2
Values 18 3.2 2.7 8.3 4.5
[198]
HepG2 FDXR
Mean 97.8
Standard deviation 8.7
Values 92 1e+02
[199]
HepG2.C3A FDXR
Mean 54.6
Standard deviation 14
Values 45 64
[200]
HuH.7 FDXR
Mean 5.93
Standard deviation 2.4
Values 6.5 3.4 8
[201]
SNU475 FDXR
Mean 3.59
Standard deviation 0.45
Values 3.9 3.3
[202]
THLE FDXR
Mean 8.51
Standard deviation 1.3
Values 9.4 7.6
[203]
liver FDXR
Mean 2.74
Standard deviation 1.3
Values 3.3 2 4.4 1.3
[204]
ref_hepatocyte CYP39A1
Mean 7.02
Standard deviation 11
Values 0.052 1.3 0.69 8.1 25
[205]
HepG2 CYP39A1
Mean 0.464
Standard deviation 0.049
Values 0.5 0.43
[206]
HepG2.C3A CYP39A1
Mean 0.363
Standard deviation 0.032
Values 0.34 0.39
[207]
HuH.7 CYP39A1
Mean 8.71
Standard deviation 0.36
Values 8.7 9.1 8.4
[208]
SNU475 CYP39A1
Mean 0.422
Standard deviation 0.11
Values 0.35 0.5
[209]
THLE CYP39A1
Mean 1.83
Standard deviation 0.14
Values 1.9 1.7
[210]
liver CYP39A1
Mean 13.9
Standard deviation 9.4
Values 28 8.3 13 7.1
[211]
ref_hepatocyte ARNT
Mean 5.93
Standard deviation 1.4
Values 7.7 6.5 4.1 4.8 6.5
[212]
HepG2 ARNT
Mean 17.5
Standard deviation 1.2
Values 17 18
[213]
HepG2.C3A ARNT
Mean 13.5
Standard deviation 3
Values 16 11
[214]
HuH.7 ARNT
Mean 23.6
Standard deviation 6.3
Values 22 31 19
[215]
SNU475 ARNT
Mean 28.1
Standard deviation 0.55
Values 28 28
[216]
THLE ARNT
Mean 26.8
Standard deviation 1.6
Values 26 28
[217]
liver ARNT
Mean 24.4
Standard deviation 4.2
Values 29 19 26 23
[218]
ref_hepatocyte CYP21A2
Mean 5.14
Standard deviation 5.5
Values 0.5 0.83 2.4 13 9.3
[219]
HepG2 CYP21A2
Mean 0.195
Standard deviation 0.0088
Values 0.19 0.2
[220]
HepG2.C3A CYP21A2
Mean 0.66
Standard deviation 0.51
Values 1 0.3
[221]
HuH.7 CYP21A2
Mean 0.0306
Standard deviation 0.027
Values 0 0.045 0.047
[222]
SNU475 CYP21A2
Mean 0.502
Standard deviation 0.11
Values 0.43 0.58
[223]
THLE CYP21A2
Mean 0.0142
Standard deviation 0.005
Values 0.018 0.011
[224]
liver CYP21A2
Mean 6.05
Standard deviation 3.4
Values 2 6 10 5.9
[225]
ref_hepatocyte AHR
Mean 4.68
Standard deviation 3.7
Values 1.7 5.3 2.7 2.8 11
[226]
HepG2 AHR
Mean 22.5
Standard deviation 5.4
Values 19 26
[227]
HepG2.C3A AHR
Mean 24.6
Standard deviation 3.3
Values 27 22
[228]
HuH.7 AHR
Mean 47.9
Standard deviation 14
Values 46 63 34
[229]
SNU475 AHR
Mean 12.5
Standard deviation 1.6
Values 11 14
[230]
THLE AHR
Mean 26.4
Standard deviation 1.2
Values 26 27
[231]
liver AHR
Mean 40.1
Standard deviation 20
Values 28 58 19 55
[232]
ref_hepatocyte CYP7A1
Mean 4.03
Standard deviation 5.2
Values 9.8 0 0 0.69 9.7
[233]
HepG2 CYP7A1
Mean 0.438
Standard deviation 0.47
Values 0.11 0.77
[234]
HepG2.C3A CYP7A1
Mean 0.0774
Standard deviation 0.027
Values 0.058 0.097
[235]
HuH.7 CYP7A1
Mean 0.00642
Standard deviation 0.011
Values 0 0.019 0
[236]
SNU475 CYP7A1
Mean 0.00739
Standard deviation 0.0039
Values 0.0046 0.01
[237]
THLE CYP7A1
Mean 0
Standard deviation 0
Values 0 0
[238]
liver CYP7A1
Mean 0.737
Standard deviation 0.45
Values 1.1 0.94 0.82 0.079
[239]
ref_hepatocyte CYP4A22
Mean 3.13
Standard deviation 4
Values 0 0.14 0.49 7.2 7.8
[240]
HepG2 CYP4A22
Mean 0
Standard deviation 0
Values 0 0
[241]
HepG2.C3A CYP4A22
Mean 0
Standard deviation 0
Values 0 0
[242]
HuH.7 CYP4A22
Mean 0
Standard deviation 0
Values 0 0 0
[243]
SNU475 CYP4A22
Mean 0
Standard deviation 0
Values 0 0
[244]
THLE CYP4A22
Mean 0
Standard deviation 0
Values 0 0
[245]
liver CYP4A22
Mean 21.4
Standard deviation 17
Values 46 6.3 15 18
[246]
ref_hepatocyte CYP2R1
Mean 2.89
Standard deviation 1.8
Values 0 4.7 3.6 3.9 2.3
[247]
HepG2 CYP2R1
Mean 0.405
Standard deviation 0.2
Values 0.54 0.27
[248]
HepG2.C3A CYP2R1
Mean 1.25
Standard deviation 0.41
Values 1.5 0.95
[249]
HuH.7 CYP2R1
Mean 5.56
Standard deviation 0.93
Values 4.6 5.8 6.4
[250]
SNU475 CYP2R1
Mean 2.12
Standard deviation 0.069
Values 2.2 2.1
[251]
THLE CYP2R1
Mean 1.67
Standard deviation 0.39
Values 1.9 1.4
[252]
liver CYP2R1
Mean 2.24
Standard deviation 0.78
Values 3.4 1.6 2 2
[253]
ref_hepatocyte CYP4F22
Mean 2.74
Standard deviation 3.4
Values 0 0.23 8.2 3.5 1.8
[254]
HepG2 CYP4F22
Mean 0.103
Standard deviation 0.15
Values 0.21 0
[255]
HepG2.C3A CYP4F22
Mean 0
Standard deviation 0
Values 0 0
[256]
HuH.7 CYP4F22
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[257]
SNU475 CYP4F22
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[258]
THLE CYP4F22
Mean 0.0198
Standard deviation 0.0054
Values 0.024 0.016
[259]
liver CYP4F22
Mean 1.99
Standard deviation 1.8
Values 4.7 0.59 1.6 1.1
[260]
ref_hepatocyte CYP1B1
Mean 2.62
Standard deviation 3.2
Values 0.024 8 0.92 2.7 1.4
[261]
HepG2 CYP1B1
Mean 0.0437
Standard deviation 0.019
Values 0.057 0.03
[262]
HepG2.C3A CYP1B1
Mean 0.0575
Standard deviation 0.04
Values 0.029 0.086
[263]
HuH.7 CYP1B1
Mean 0.95
Standard deviation 0.082
Values 0.87 1 0.95
[264]
SNU475 CYP1B1
Mean 13.6
Standard deviation 3.1
Values 16 11
[265]
THLE CYP1B1
Mean 93
Standard deviation 14
Values 1e+02 83
[266]
liver CYP1B1
Mean 7.5
Standard deviation 1.4
Values 6.9 7.4 9.5 6.2
[267]
ref_hepatocyte NCOA1
Mean 2.09
Standard deviation 0.73
Values 1.8 2 1.1 2.8 2.8
[268]
HepG2 NCOA1
Mean 6.38
Standard deviation 1.4
Values 5.4 7.4
[269]
HepG2.C3A NCOA1
Mean 8.42
Standard deviation 0.79
Values 7.9 9
[270]
HuH.7 NCOA1
Mean 9.25
Standard deviation 2.7
Values 9.2 12 6.6
[271]
SNU475 NCOA1
Mean 13.3
Standard deviation 1
Values 14 13
[272]
THLE NCOA1
Mean 10.2
Standard deviation 0.47
Values 9.9 11
[273]
liver NCOA1
Mean 18.7
Standard deviation 4.8
Values 17 23 13 22
[274]
ref_hepatocyte CYP3A43
Mean 1.46
Standard deviation 2.7
Values 0.059 0 0 1.1 6.1
[275]
HepG2 CYP3A43
Mean 0.112
Standard deviation 0.061
Values 0.069 0.15
[276]
HepG2.C3A CYP3A43
Mean 0.735
Standard deviation 0.42
Values 1 0.44
[277]
HuH.7 CYP3A43
Mean 0.622
Standard deviation 0.91
Values 0.057 1.7 0.14
[278]
SNU475 CYP3A43
Mean 0
Standard deviation 0
Values 0 0
[279]
THLE CYP3A43
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[280]
liver CYP3A43
Mean 5.41
Standard deviation 4.2
Values 12 2.9 3.4 3.6
[281]
ref_hepatocyte CYP7B1
Mean 1.44
Standard deviation 1
Values 0 2.2 1.1 1.2 2.7
[282]
HepG2 CYP7B1
Mean 0.0122
Standard deviation 0.001
Values 0.011 0.013
[283]
HepG2.C3A CYP7B1
Mean 0.0263
Standard deviation 0.023
Values 0.0097 0.043
[284]
HuH.7 CYP7B1
Mean 0
Standard deviation 0
Values 0 0 0
[285]
SNU475 CYP7B1
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[286]
THLE CYP7B1
Mean 0.0751
Standard deviation 0.014
Values 0.065 0.085
[287]
liver CYP7B1
Mean 9.87
Standard deviation 5.4
Values 6.3 17 4.8 12
[288]
ref_hepatocyte NCOA2
Mean 1.14
Standard deviation 0.47
Values 1.5 1.7 1.2 0.47 0.91
[289]
HepG2 NCOA2
Mean 7.51
Standard deviation 4.4
Values 4.4 11
[290]
HepG2.C3A NCOA2
Mean 11.8
Standard deviation 4.3
Values 8.7 15
[291]
HuH.7 NCOA2
Mean 40.1
Standard deviation 18
Values 55 45 21
[292]
SNU475 NCOA2
Mean 19.2
Standard deviation 3.8
Values 22 17
[293]
THLE NCOA2
Mean 6.6
Standard deviation 1.4
Values 5.6 7.6
[294]
liver NCOA2
Mean 39.3
Standard deviation 20
Values 25 56 20 57
[295]
ref_hepatocyte CYP19A1
Mean 1.13
Standard deviation 2.3
Values 5.3 0.08 0.28 0 0
[296]
HepG2 CYP19A1
Mean 9.51
Standard deviation 0.87
Values 8.9 10
[297]
HepG2.C3A CYP19A1
Mean 17.1
Standard deviation 5.6
Values 21 13
[298]
HuH.7 CYP19A1
Mean 0.188
Standard deviation 0.27
Values 0.016 0.5 0.047
[299]
SNU475 CYP19A1
Mean 0.66
Standard deviation 0.58
Values 0.25 1.1
[300]
THLE CYP19A1
Mean 0.135
Standard deviation 0.018
Values 0.15 0.12
[301]
liver CYP19A1
Mean 0.0199
Standard deviation 0.04
Values 0 0 0 0.079
[302]
ref_hepatocyte CYP2U1
Mean 1.09
Standard deviation 0.48
Values 0.81 1.1 0.46 1.4 1.7
[303]
HepG2 CYP2U1
Mean 2.73
Standard deviation 0.62
Values 2.3 3.2
[304]
HepG2.C3A CYP2U1
Mean 0.173
Standard deviation 0.15
Values 0.068 0.28
[305]
HuH.7 CYP2U1
Mean 0.192
Standard deviation 0.045
Values 0.16 0.17 0.24
[306]
SNU475 CYP2U1
Mean 4.71
Standard deviation 1
Values 5.4 4
[307]
THLE CYP2U1
Mean 9.13
Standard deviation 0.16
Values 9 9.2
[308]
liver CYP2U1
Mean 6.54
Standard deviation 1.6
Values 5.5 8.3 7.4 5
[309]
ref_hepatocyte POMC
Mean 0.898
Standard deviation 0.87
Values 0 1.1 0 1.4 2
[310]
HepG2 POMC
Mean 0
Standard deviation 0
Values 0 0
[311]
HepG2.C3A POMC
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[312]
HuH.7 POMC
Mean 0
Standard deviation 0
Values 0 0 0
[313]
SNU475 POMC
Mean 0
Standard deviation 0
Values 0 0
[314]
THLE POMC
Mean 0.0133
Standard deviation 0.019
Values 0 0.027
[315]
liver POMC
Mean 0.28
Standard deviation 0.16
Values 0.35 0.17 0.46 0.13
[316]
ref_hepatocyte TBXAS1
Mean 0.896
Standard deviation 0.62
Values 0.56 0.49 0.32 1.7 1.4
[317]
HepG2 TBXAS1
Mean 0.253
Standard deviation 0.096
Values 0.32 0.18
[318]
HepG2.C3A TBXAS1
Mean 0.938
Standard deviation 0.16
Values 1 0.83
[319]
HuH.7 TBXAS1
Mean 0.0986
Standard deviation 0.058
Values 0.12 0.032 0.14
[320]
SNU475 TBXAS1
Mean 2.57
Standard deviation 0.093
Values 2.5 2.6
[321]
THLE TBXAS1
Mean 1.05
Standard deviation 0.095
Values 1.1 0.98
[322]
liver TBXAS1
Mean 4
Standard deviation 1.4
Values 2.1 4.8 4.1 5.1
[323]
ref_hepatocyte CYP11A1
Mean 0.602
Standard deviation 0.44
Values 0.18 0.47 0.44 0.59 1.3
[324]
HepG2 CYP11A1
Mean 0.843
Standard deviation 0.49
Values 1.2 0.49
[325]
HepG2.C3A CYP11A1
Mean 0.131
Standard deviation 0.049
Values 0.17 0.097
[326]
HuH.7 CYP11A1
Mean 0
Standard deviation 0
Values 0 0 0
[327]
SNU475 CYP11A1
Mean 0.115
Standard deviation 0.045
Values 0.083 0.15
[328]
THLE CYP11A1
Mean 2.14
Standard deviation 0.87
Values 2.8 1.5
[329]
liver CYP11A1
Mean 1.18
Standard deviation 0.65
Values 1.4 0.57 2 0.75
[330]
ref_hepatocyte CYP2W1
Mean 0.591
Standard deviation 1.2
Values 2.8 0 0 0.16 0
[331]
HepG2 CYP2W1
Mean 16.9
Standard deviation 4.5
Values 14 20
[332]
HepG2.C3A CYP2W1
Mean 56.5
Standard deviation 39
Values 84 29
[333]
HuH.7 CYP2W1
Mean 0.798
Standard deviation 0.23
Values 0.68 1.1 0.65
[334]
SNU475 CYP2W1
Mean 0.101
Standard deviation 0.028
Values 0.12 0.081
[335]
THLE CYP2W1
Mean 0.0849
Standard deviation 0.022
Values 0.1 0.069
[336]
liver CYP2W1
Mean 0.0517
Standard deviation 0.06
Values 0 0.11 0 0.093
[337]
ref_hepatocyte CYP2S1
Mean 0.536
Standard deviation 0.51
Values 0.27 0.31 1.4 0.1 0.61
[338]
HepG2 CYP2S1
Mean 8.91
Standard deviation 2.7
Values 11 7
[339]
HepG2.C3A CYP2S1
Mean 3.61
Standard deviation 0.85
Values 4.2 3
[340]
HuH.7 CYP2S1
Mean 1.97
Standard deviation 1.2
Values 3 0.73 2.2
[341]
SNU475 CYP2S1
Mean 2.23
Standard deviation 1.5
Values 1.2 3.3
[342]
THLE CYP2S1
Mean 2.64
Standard deviation 0.9
Values 2 3.3
[343]
liver CYP2S1
Mean 0.486
Standard deviation 0.16
Values 0.38 0.4 0.72 0.45
[344]
ref_hepatocyte CYP24A1
Mean 0.344
Standard deviation 0.69
Values 1.6 0.15 0 0 0
[345]
HepG2 CYP24A1
Mean 215
Standard deviation 90
Values 2.8e+02 1.5e+02
[346]
HepG2.C3A CYP24A1
Mean 6.56
Standard deviation 2.9
Values 4.5 8.6
[347]
HuH.7 CYP24A1
Mean 0.126
Standard deviation 0.11
Values 0.11 0.24 0.019
[348]
SNU475 CYP24A1
Mean 10.9
Standard deviation 10
Values 3.8 18
[349]
THLE CYP24A1
Mean 0.109
Standard deviation 0.079
Values 0.053 0.16
[350]
liver CYP24A1
Mean 0.00357
Standard deviation 0.0071
Values 0 0.014 0 0
[351]
ref_hepatocyte CYP26A1
Mean 0.247
Standard deviation 0.38
Values 0 0 0 0.86 0.37
[352]
HepG2 CYP26A1
Mean 4.9
Standard deviation 3.4
Values 7.3 2.5
[353]
HepG2.C3A CYP26A1
Mean 0.0764
Standard deviation 0.0019
Values 0.078 0.075
[354]
HuH.7 CYP26A1
Mean 0.853
Standard deviation 0.36
Values 0.55 1.3 0.76
[355]
SNU475 CYP26A1
Mean 0.504
Standard deviation 0.37
Values 0.77 0.24
[356]
THLE CYP26A1
Mean 0.0109
Standard deviation 0.0071
Values 0.0059 0.016
[357]
liver CYP26A1
Mean 0.705
Standard deviation 0.82
Values 0.19 0.74 1.8 0.04
[358]
ref_hepatocyte PTGIS
Mean 0.218
Standard deviation 0.14
Values 0.14 0.08 0.32 0.4 0.15
[359]
HepG2 PTGIS
Mean 0.163
Standard deviation 0.012
Values 0.17 0.15
[360]
HepG2.C3A PTGIS
Mean 0.316
Standard deviation 0.0069
Values 0.32 0.31
[361]
HuH.7 PTGIS
Mean 4.77
Standard deviation 0.64
Values 5.5 4.3 4.5
[362]
SNU475 PTGIS
Mean 0.868
Standard deviation 0.11
Values 0.79 0.94
[363]
THLE PTGIS
Mean 59.9
Standard deviation 32
Values 37 82
[364]
liver PTGIS
Mean 8.86
Standard deviation 2.8
Values 5.9 11 12 7.1
[365]
ref_hepatocyte AHRR
Mean 0.118
Standard deviation 0.18
Values 0.44 0.06 0 0.026 0.065
[366]
HepG2 AHRR
Mean 0.681
Standard deviation 0.23
Values 0.84 0.52
[367]
HepG2.C3A AHRR
Mean 0.329
Standard deviation 0.22
Values 0.49 0.17
[368]
HuH.7 AHRR
Mean 0.388
Standard deviation 0.1
Values 0.3 0.37 0.5
[369]
SNU475 AHRR
Mean 5.99
Standard deviation 1.7
Values 7.2 4.8
[370]
THLE AHRR
Mean 2.19
Standard deviation 0.32
Values 2.4 2
[371]
liver AHRR
Mean 0.277
Standard deviation 0.057
Values 0.33 0.26 0.21 0.32
[372]
ref_hepatocyte CYP2A13
Mean 0.0683
Standard deviation 0.12
Values 0 0 0 0.28 0.057
[373]
HepG2 CYP2A13
Mean 0
Standard deviation 0
Values 0 0
[374]
HepG2.C3A CYP2A13
Mean 0
Standard deviation 0
Values 0 0
[375]
HuH.7 CYP2A13
Mean 0
Standard deviation 0
Values 0 0 0
[376]
SNU475 CYP2A13
Mean 0
Standard deviation 0
Values 0 0
[377]
THLE CYP2A13
Mean 0
Standard deviation 0
Values 0 0
[378]
liver CYP2A13
Mean 0.0677
Standard deviation 0.059
Values 0 0.13 0.1 0.04
[379]
ref_hepatocyte CYP27B1
Mean 0.0505
Standard deviation 0.082
Values 0 0 0.19 0 0.065
[380]
HepG2 CYP27B1
Mean 0.715
Standard deviation 0.14
Values 0.62 0.81
[381]
HepG2.C3A CYP27B1
Mean 1.72
Standard deviation 0.25
Values 1.9 1.5
[382]
HuH.7 CYP27B1
Mean 1.08
Standard deviation 0.18
Values 1.1 0.89 1.3
[383]
SNU475 CYP27B1
Mean 0.211
Standard deviation 0.1
Values 0.14 0.28
[384]
THLE CYP27B1
Mean 0.395
Standard deviation 0.14
Values 0.5 0.29
[385]
liver CYP27B1
Mean 0.228
Standard deviation 0.17
Values 0.071 0.14 0.46 0.24
[386]
ref_hepatocyte CYP46A1
Mean 0.0447
Standard deviation 0.068
Values 0 0 0 0.069 0.15
[387]
HepG2 CYP46A1
Mean 0.00716
Standard deviation 0.002
Values 0.0057 0.0086
[388]
HepG2.C3A CYP46A1
Mean 0.0161
Standard deviation 0.023
Values 0 0.032
[389]
HuH.7 CYP46A1
Mean 0.00761
Standard deviation 0.0083
Values 0.016 0.0064 0
[390]
SNU475 CYP46A1
Mean 0.0139
Standard deviation 0.02
Values 0.028 0
[391]
THLE CYP46A1
Mean 0.0358
Standard deviation 0.017
Values 0.024 0.048
[392]
liver CYP46A1
Mean 0.303
Standard deviation 0.093
Values 0.38 0.17 0.36 0.3
[393]
ref_hepatocyte CYP2F1
Mean 0.026
Standard deviation 0.058
Values 0 0 0 0 0.13
[394]
HepG2 CYP2F1
Mean 0.0336
Standard deviation 0.007
Values 0.029 0.039
[395]
HepG2.C3A CYP2F1
Mean 0.00972
Standard deviation 0.014
Values 0.019 0
[396]
HuH.7 CYP2F1
Mean 0.185
Standard deviation 0.058
Values 0.16 0.25 0.14
[397]
SNU475 CYP2F1
Mean 0.129
Standard deviation 0.047
Values 0.16 0.096
[398]
THLE CYP2F1
Mean 0.0674
Standard deviation 0.0051
Values 0.071 0.064
[399]
liver CYP2F1
Mean 0.0726
Standard deviation 0.035
Values 0.024 0.071 0.1 0.093
[400]
ref_hepatocyte ARNT2
Mean 0.0152
Standard deviation 0.021
Values 0.035 0 0 0 0.041
[401]
HepG2 ARNT2
Mean 1.4
Standard deviation 0.00016
Values 1.4 1.4
[402]
HepG2.C3A ARNT2
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[403]
HuH.7 ARNT2
Mean 0.0117
Standard deviation 0.01
Values 0.016 0 0.019
[404]
SNU475 ARNT2
Mean 2.4
Standard deviation 1.8
Values 3.7 1.1
[405]
THLE ARNT2
Mean 9.12
Standard deviation 1.9
Values 7.8 10
[406]
liver ARNT2
Mean 0.665
Standard deviation 0.33
Values 0.38 0.67 0.49 1.1
[407]
ref_hepatocyte CYP26B1
Mean 0.0121
Standard deviation 0.027
Values 0 0 0 0.06 0
[408]
HepG2 CYP26B1
Mean 0.791
Standard deviation 0.35
Values 1 0.54
[409]
HepG2.C3A CYP26B1
Mean 0.0848
Standard deviation 0.092
Values 0.019 0.15
[410]
HuH.7 CYP26B1
Mean 12
Standard deviation 3.7
Values 14 7.7 14
[411]
SNU475 CYP26B1
Mean 2.31
Standard deviation 2.1
Values 0.84 3.8
[412]
THLE CYP26B1
Mean 1.52
Standard deviation 0.59
Values 1.9 1.1
[413]
liver CYP26B1
Mean 0.794
Standard deviation 0.48
Values 0.78 0.43 0.49 1.5
[414]
ref_hepatocyte CYP11B2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[415]
HepG2 CYP11B2
Missing
[416]
HepG2.C3A CYP11B2
Missing
[417]
HuH.7 CYP11B2
Missing
[418]
SNU475 CYP11B2
Missing
[419]
THLE CYP11B2
Missing
[420]
liver CYP11B2
Missing
[421]
ref_hepatocyte CYP11B1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[422]
HepG2 CYP11B1
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[423]
HepG2.C3A CYP11B1
Mean 0
Standard deviation 0
Values 0 0
[424]
HuH.7 CYP11B1
Mean 0
Standard deviation 0
Values 0 0 0
[425]
SNU475 CYP11B1
Mean 0
Standard deviation 0
Values 0 0
[426]
THLE CYP11B1
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[427]
liver CYP11B1
Mean 0.00331
Standard deviation 0.0066
Values 0 0 0 0.013
[428]
ref_hepatocyte CYP4B1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[429]
HepG2 CYP4B1
Mean 0.00501
Standard deviation 0.001
Values 0.0057 0.0043
[430]
HepG2.C3A CYP4B1
Mean 0
Standard deviation 0
Values 0 0
[431]
HuH.7 CYP4B1
Mean 0
Standard deviation 0
Values 0 0 0
[432]
SNU475 CYP4B1
Mean 0.0177
Standard deviation 0.025
Values 0 0.035
[433]
THLE CYP4B1
Mean 0.129
Standard deviation 0.077
Values 0.18 0.074
[434]
liver CYP4B1
Mean 0.0575
Standard deviation 0.045
Values 0.047 0 0.077 0.11
[435]
ref_hepatocyte CYP4F8
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[436]
HepG2 CYP4F8
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[437]
HepG2.C3A CYP4F8
Mean 0
Standard deviation 0
Values 0 0
[438]
HuH.7 CYP4F8
Mean 0.00312
Standard deviation 0.0054
Values 0 0 0.0094
[439]
SNU475 CYP4F8
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[440]
THLE CYP4F8
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[441]
liver CYP4F8
Mean 0
Standard deviation 0
Values 0 0 0 0
[442]
ref_hepatocyte PDCD6-AHRR
Missing
[443]
HepG2 PDCD6-AHRR
Missing
[444]
HepG2.C3A PDCD6-AHRR
Missing
[445]
HuH.7 PDCD6-AHRR
Missing
[446]
SNU475 PDCD6-AHRR
Missing
[447]
THLE PDCD6-AHRR
Missing
[448]
liver PDCD6-AHRR
Missing
[449]
ref_hepatocyte CYP26C1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[450]
HepG2 CYP26C1
Mean 0
Standard deviation 0
Values 0 0
[451]
HepG2.C3A CYP26C1
Mean 0
Standard deviation 0
Values 0 0
[452]
HuH.7 CYP26C1
Mean 0.176
Standard deviation 0.084
Values 0.26 0.17 0.094
[453]
SNU475 CYP26C1
Mean 0
Standard deviation 0
Values 0 0
[454]
THLE CYP26C1
Mean 0.0166
Standard deviation 0.0067
Values 0.012 0.021
[455]
liver CYP26C1
Mean 0.0165
Standard deviation 0.033
Values 0 0 0 0.066
[456]
ref_hepatocyte FDX2
Missing
[457]
HepG2 FDX2
Missing
[458]
HepG2.C3A FDX2
Missing
[459]
HuH.7 FDX2
Missing
[460]
SNU475 FDX2
Missing
[461]
THLE FDX2
Missing
[462]
liver FDX2
Missing