REACTOME_CYP2E1_REACTIONS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CYP2E1 Cytochrome P450 2E1 [1] -5.41[2] -5.30[3] -2.53[4] -5.75[5] -4.18[6] -0.54[7]
2 CYP2C8 Cytochrome P450 2C8 [8] -7.40[9] -2.41[10] -0.69[11] -2.83[12] [13] 0.38[14]
3 CYP2C9 Cytochrome P450 2C9 [15] [16] -7.33[17] -0.91[18] -5.52[19] -4.71[20] 0.88[21]
4 CYP2A6 Cytochrome P450 2A6 [22] -8.78[23] [24] -1.15[25] -2.59[26] -5.01[27] -1.75[28]
5 CYP2B6 Cytochrome P450 2B6 [29] -0.56[30] 3.13[31] 4.03[32] -0.39[33] -1.38[34] 2.26[35]
6 CYP2D6 Cytochrome P450 2D6 [36] 1.18[37] 3.92[38] 0.91[39] 1.10[40] 0.59[41] 1.09[42]
7 CYP2C19 Cytochrome P450 2C19 [43] [44] [45] 1.95[46] -3.21[47] -3.01[48] 1.44[49]
8 CYP2A7 Cytochrome P450 2A7 [50] [51] [52] 3.44[53] -1.19[54] [55] -1.90[56]
9 CYP2S1 Cytochrome P450 2S1 [57] 12.00[58] 11.12[59] 9.83[60] 11.86[61] 11.95[62] -0.78[63]
10 CYP2A13 Cytochrome P450 2A13 [64] [65] [66] [67] [68] [69] -0.65[70]
11 CYP2F1 Cytochrome P450 2F1 [71] 8.31[72] 6.95[73] 10.78[74] 12.12[75] 11.03[76] 0.84[77]
[1]
ref_hepatocyte CYP2E1
Mean 1.39e+03
Standard deviation 1.9e+03
Values 0 4.6 90 2.7e+03 4.1e+03
[2]
HepG2 CYP2E1
Mean 0.133
Standard deviation 0.1
Values 0.21 0.06
[3]
HepG2.C3A CYP2E1
Mean 0.107
Standard deviation 0.15
Values 0.21 0
[4]
HuH.7 CYP2E1
Mean 0.975
Standard deviation 0.29
Values 0.67 1.3 0.99
[5]
SNU475 CYP2E1
Mean 0.0289
Standard deviation 0.005
Values 0.032 0.025
[6]
THLE CYP2E1
Mean 0.0955
Standard deviation 0.082
Values 0.15 0.037
[7]
liver CYP2E1
Mean 1.49e+03
Standard deviation 8.2e+02
Values 2.6e+03 1e+03 1.7e+03 6.9e+02
[8]
ref_hepatocyte CYP2C8
Mean 328
Standard deviation 4.4e+02
Values 0 1.2 19 7.1e+02 9.1e+02
[9]
HepG2 CYP2C8
Mean 0.00788
Standard deviation 0.0051
Values 0.011 0.0043
[10]
HepG2.C3A CYP2C8
Mean 0.186
Standard deviation 0.071
Values 0.14 0.24
[11]
HuH.7 CYP2C8
Mean 0.822
Standard deviation 1
Values 0.16 2 0.3
[12]
SNU475 CYP2C8
Mean 0.0515
Standard deviation 0.02
Values 0.037 0.066
[13]
THLE CYP2C8
Mean 0
Standard deviation 0
Values 0 0
[14]
liver CYP2C8
Mean 666
Standard deviation 3.9e+02
Values 6.8e+02 6.2e+02 1.2e+03 2e+02
[15]
ref_hepatocyte CYP2C9
Mean 285
Standard deviation 4.1e+02
Values 0.064 20 21 4.7e+02 9.2e+02
[16]
HepG2 CYP2C9
Mean 0
Standard deviation 0
Values 0 0
[17]
HepG2.C3A CYP2C9
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[18]
HuH.7 CYP2C9
Mean 0.616
Standard deviation 0.63
Values 0.25 1.3 0.25
[19]
SNU475 CYP2C9
Mean 0.00696
Standard deviation 0.0098
Values 0.014 0
[20]
THLE CYP2C9
Mean 0.0136
Standard deviation 0.011
Values 0.0059 0.021
[21]
liver CYP2C9
Mean 822
Standard deviation 5.3e+02
Values 8.6e+02 6.1e+02 1.5e+03 2.9e+02
[22]
ref_hepatocyte CYP2A6
Mean 231
Standard deviation 3e+02
Values 0 4.6 38 5.6e+02 5.5e+02
[23]
HepG2 CYP2A6
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[24]
HepG2.C3A CYP2A6
Mean 0
Standard deviation 0
Values 0 0
[25]
HuH.7 CYP2A6
Mean 0.421
Standard deviation 0.53
Values 0.11 1 0.12
[26]
SNU475 CYP2A6
Mean 0.0428
Standard deviation 0.025
Values 0.06 0.025
[27]
THLE CYP2A6
Mean 0.00887
Standard deviation 0.013
Values 0.018 0
[28]
liver CYP2A6
Mean 107
Standard deviation 1e+02
Values 29 1.8e+02 2.1e+02 13
[29]
ref_hepatocyte CYP2B6
Mean 49.6
Standard deviation 62
Values 0 4.1 12 1.3e+02 1e+02
[30]
HepG2 CYP2B6
Mean 0.138
Standard deviation 0.15
Values 0.24 0.034
[31]
HepG2.C3A CYP2B6
Mean 1.32
Standard deviation 0.56
Values 1.7 0.92
[32]
HuH.7 CYP2B6
Mean 3.27
Standard deviation 2.3
Values 2.1 5.9 1.9
[33]
SNU475 CYP2B6
Mean 0.0424
Standard deviation 0.04
Values 0.014 0.071
[34]
THLE CYP2B6
Mean 0.0237
Standard deviation 0.033
Values 0.047 0
[35]
liver CYP2B6
Mean 372
Standard deviation 5.3e+02
Values 23 3.2e+02 1.1e+03 7.4
[36]
ref_hepatocyte CYP2D6
Mean 41.3
Standard deviation 55
Values 0.24 0.47 3.7 1.1e+02 87
[37]
HepG2 CYP2D6
Mean 0.382
Standard deviation 0.03
Values 0.36 0.4
[38]
HepG2.C3A CYP2D6
Mean 1.89
Standard deviation 1
Values 2.6 1.2
[39]
HuH.7 CYP2D6
Mean 0.314
Standard deviation 0.087
Values 0.23 0.4 0.31
[40]
SNU475 CYP2D6
Mean 0.0992
Standard deviation 0.004
Values 0.1 0.096
[41]
THLE CYP2D6
Mean 0.0775
Standard deviation 0.049
Values 0.11 0.043
[42]
liver CYP2D6
Mean 137
Standard deviation 1.2e+02
Values 3.1e+02 53 1.3e+02 57
[43]
ref_hepatocyte CYP2C19
Mean 19.2
Standard deviation 30
Values 0 5.9 0 18 72
[44]
HepG2 CYP2C19
Mean 0
Standard deviation 0
Values 0 0
[45]
HepG2.C3A CYP2C19
Mean 0
Standard deviation 0
Values 0 0
[46]
HuH.7 CYP2C19
Mean 0.3
Standard deviation 0.27
Values 0.098 0.6 0.2
[47]
SNU475 CYP2C19
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[48]
THLE CYP2C19
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[49]
liver CYP2C19
Mean 81.4
Standard deviation 39
Values 65 92 1.3e+02 38
[50]
ref_hepatocyte CYP2A7
Mean 15.1
Standard deviation 22
Values 0 0.06 11 52 12
[51]
HepG2 CYP2A7
Mean 0
Standard deviation 0
Values 0 0
[52]
HepG2.C3A CYP2A7
Mean 0
Standard deviation 0
Values 0 0
[53]
HuH.7 CYP2A7
Mean 0.663
Standard deviation 0.76
Values 0.16 1.5 0.3
[54]
SNU475 CYP2A7
Mean 0.00739
Standard deviation 0.0039
Values 0.0046 0.01
[55]
THLE CYP2A7
Mean 0
Standard deviation 0
Values 0 0
[56]
liver CYP2A7
Mean 6.31
Standard deviation 5.5
Values 2 13 9 1.4
[57]
ref_hepatocyte CYP2S1
Mean 0.536
Standard deviation 0.51
Values 0.27 0.31 1.4 0.1 0.61
[58]
HepG2 CYP2S1
Mean 8.91
Standard deviation 2.7
Values 11 7
[59]
HepG2.C3A CYP2S1
Mean 3.61
Standard deviation 0.85
Values 4.2 3
[60]
HuH.7 CYP2S1
Mean 1.97
Standard deviation 1.2
Values 3 0.73 2.2
[61]
SNU475 CYP2S1
Mean 2.23
Standard deviation 1.5
Values 1.2 3.3
[62]
THLE CYP2S1
Mean 2.64
Standard deviation 0.9
Values 2 3.3
[63]
liver CYP2S1
Mean 0.486
Standard deviation 0.16
Values 0.38 0.4 0.72 0.45
[64]
ref_hepatocyte CYP2A13
Mean 0.0683
Standard deviation 0.12
Values 0 0 0 0.28 0.057
[65]
HepG2 CYP2A13
Mean 0
Standard deviation 0
Values 0 0
[66]
HepG2.C3A CYP2A13
Mean 0
Standard deviation 0
Values 0 0
[67]
HuH.7 CYP2A13
Mean 0
Standard deviation 0
Values 0 0 0
[68]
SNU475 CYP2A13
Mean 0
Standard deviation 0
Values 0 0
[69]
THLE CYP2A13
Mean 0
Standard deviation 0
Values 0 0
[70]
liver CYP2A13
Mean 0.0677
Standard deviation 0.059
Values 0 0.13 0.1 0.04
[71]
ref_hepatocyte CYP2F1
Mean 0.026
Standard deviation 0.058
Values 0 0 0 0 0.13
[72]
HepG2 CYP2F1
Mean 0.0336
Standard deviation 0.007
Values 0.029 0.039
[73]
HepG2.C3A CYP2F1
Mean 0.00972
Standard deviation 0.014
Values 0.019 0
[74]
HuH.7 CYP2F1
Mean 0.185
Standard deviation 0.058
Values 0.16 0.25 0.14
[75]
SNU475 CYP2F1
Mean 0.129
Standard deviation 0.047
Values 0.16 0.096
[76]
THLE CYP2F1
Mean 0.0674
Standard deviation 0.0051
Values 0.071 0.064
[77]
liver CYP2F1
Mean 0.0726
Standard deviation 0.035
Values 0.024 0.071 0.1 0.093