REACTOME_CS_DS_DEGRADATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 HYAL1 Hyaluronidase-1 [1] -0.97[2] -0.22[3] -5.40[4] -8.87[5] -7.37[6] -0.90[7]
2 HEXB Beta-hexosaminidase subunit beta [8] -0.69[9] -0.58[10] 0.59[11] -0.40[12] -0.34[13] -1.00[14]
3 HEXA Beta-hexosaminidase subunit alpha [15] 0.98[16] 0.81[17] 1.11[18] 1.20[19] 0.41[20] -0.45[21]
4 IDS Iduronate 2-sulfatase [22] -0.25[23] -0.31[24] -0.26[25] 2.36[26] 0.81[27] 0.49[28]
5 ARSB Arylsulfatase B [29] 3.18[30] 2.27[31] 2.25[32] 1.85[33] 1.63[34] 1.45[35]
6 IDUA Alpha-L-iduronidase [36] -2.86[37] -1.79[38] -0.81[39] 1.08[40] -1.30[41] -0.62[42]
7 HYAL3 Hyaluronidase-3 [43] 1.51[44] 1.07[45] 2.00[46] -0.51[47] -0.32[48] -1.66[49]
8 DCN Decorin [50] -6.80[51] -8.03[52] -4.54[53] 1.88[54] 5.33[55] 5.00[56]
9 BGN Biglycan [57] 1.50[58] -3.23[59] -4.88[60] 2.12[61] -1.13[62] 4.65[63]
10 VCAN Versican core protein [64] 4.28[65] -0.38[66] 4.35[67] 1.83[68] 5.41[69] 3.13[70]
11 CSPG5 Chondroitin sulfate proteoglycan 5 [71] -1.67[72] -3.90[73] 2.58[74] 1.49[75] -1.34[76] -2.92[77]
12 NCAN Neurocan core protein [78] 1.25[79] -1.04[80] 1.90[81] -3.22[82] -1.07[83] -1.53[84]
13 CSPG4 Chondroitin sulfate proteoglycan 4 [85] 3.08[86] 2.59[87] 5.00[88] 7.50[89] 7.45[90] 5.10[91]
14 BCAN Brevican core protein [92] 7.74[93] 8.43[94] 7.27[95] 7.69[96] 4.93[97] 2.01[98]
[1]
ref_hepatocyte HYAL1
Mean 53.9
Standard deviation 39
Values 18 24 36 90 1e+02
[2]
HepG2 HYAL1
Mean 83.6
Standard deviation 4.4
Values 81 87
[3]
HepG2.C3A HYAL1
Mean 88.6
Standard deviation 33
Values 1.1e+02 65
[4]
HuH.7 HYAL1
Mean 1.54
Standard deviation 0.96
Values 0.95 2.7 1
[5]
SNU475 HYAL1
Mean 0.168
Standard deviation 0.058
Values 0.21 0.13
[6]
THLE HYAL1
Mean 0.868
Standard deviation 0.069
Values 0.92 0.82
[7]
liver HYAL1
Mean 66.7
Standard deviation 12
Values 80 54 73 59
[8]
ref_hepatocyte HEXB
Mean 33.9
Standard deviation 11
Values 39 33 16 44 38
[9]
HepG2 HEXB
Mean 64.1
Standard deviation 5.9
Values 68 60
[10]
HepG2.C3A HEXB
Mean 43.4
Standard deviation 2.1
Values 45 42
[11]
HuH.7 HEXB
Mean 61.5
Standard deviation 15
Values 46 77 61
[12]
SNU475 HEXB
Mean 37.4
Standard deviation 0.5
Values 37 38
[13]
THLE HEXB
Mean 71.3
Standard deviation 17
Values 59 83
[14]
liver HEXB
Mean 39
Standard deviation 15
Values 42 34 57 22
[15]
ref_hepatocyte HEXA
Mean 15.3
Standard deviation 8.5
Values 11 11 6.1 25 24
[16]
HepG2 HEXA
Mean 91.6
Standard deviation 1.4
Values 93 91
[17]
HepG2.C3A HEXA
Mean 51.3
Standard deviation 2.1
Values 53 50
[18]
HuH.7 HEXA
Mean 39.8
Standard deviation 6.4
Values 37 35 47
[19]
SNU475 HEXA
Mean 51.2
Standard deviation 9
Values 58 45
[20]
THLE HEXA
Mean 54.1
Standard deviation 9.1
Values 48 61
[21]
liver HEXA
Mean 25.8
Standard deviation 15
Values 28 17 46 12
[22]
ref_hepatocyte IDS
Mean 6.6
Standard deviation 4
Values 1.7 8.7 12 5 5.4
[23]
HepG2 IDS
Mean 16.9
Standard deviation 2.4
Values 19 15
[24]
HepG2.C3A IDS
Mean 10.2
Standard deviation 0.54
Values 9.8 11
[25]
HuH.7 IDS
Mean 6.65
Standard deviation 2.1
Values 5.9 9 5
[26]
SNU475 IDS
Mean 49.1
Standard deviation 1.7
Values 50 48
[27]
THLE IDS
Mean 30.9
Standard deviation 4
Values 28 34
[28]
liver IDS
Mean 21.3
Standard deviation 4.6
Values 27 15 22 22
[29]
ref_hepatocyte ARSB
Mean 1.85
Standard deviation 1.5
Values 4.3 0.43 1.1 1.1 2.3
[30]
HepG2 ARSB
Mean 50.8
Standard deviation 1.2
Values 50 52
[31]
HepG2.C3A ARSB
Mean 17.1
Standard deviation 4.2
Values 14 20
[32]
HuH.7 ARSB
Mean 10.6
Standard deviation 2.5
Values 12 7.7 12
[33]
SNU475 ARSB
Mean 9.69
Standard deviation 3.6
Values 12 7.1
[34]
THLE ARSB
Mean 15.3
Standard deviation 3.2
Values 13 18
[35]
liver ARSB
Mean 11.6
Standard deviation 6.3
Values 7.9 11 6.6 21
[36]
ref_hepatocyte IDUA
Mean 1.21
Standard deviation 1.4
Values 0 0.052 0.69 3.2 2.1
[37]
HepG2 IDUA
Mean 0.506
Standard deviation 0.019
Values 0.49 0.52
[38]
HepG2.C3A IDUA
Mean 0.666
Standard deviation 0.49
Values 1 0.32
[39]
HuH.7 IDUA
Mean 0.828
Standard deviation 0.42
Values 0.39 1.2 0.85
[40]
SNU475 IDUA
Mean 3.72
Standard deviation 1.5
Values 4.8 2.7
[41]
THLE IDUA
Mean 1.31
Standard deviation 0.3
Values 1.5 1.1
[42]
liver IDUA
Mean 1.81
Standard deviation 0.66
Values 2.7 1.1 1.9 1.6
[43]
ref_hepatocyte HYAL3
Mean 1.18
Standard deviation 1
Values 0.37 0.22 2.6 0.75 2
[44]
HepG2 HYAL3
Mean 10.2
Standard deviation 1.5
Values 9.2 11
[45]
HepG2.C3A HYAL3
Mean 4.74
Standard deviation 0.039
Values 4.8 4.7
[46]
HuH.7 HYAL3
Mean 5.68
Standard deviation 0.29
Values 5.4 5.7 6
[47]
SNU475 HYAL3
Mean 1.21
Standard deviation 0.21
Values 1.1 1.4
[48]
THLE HYAL3
Mean 2.51
Standard deviation 0.14
Values 2.4 2.6
[49]
liver HYAL3
Mean 0.856
Standard deviation 0.5
Values 1.4 0.26 1.1 0.65
[50]
ref_hepatocyte DCN
Mean 0.734
Standard deviation 1.2
Values 0 0 0.17 0.72 2.8
[51]
HepG2 DCN
Mean 0.02
Standard deviation 0.0041
Values 0.023 0.017
[52]
HepG2.C3A DCN
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[53]
HuH.7 DCN
Mean 0.038
Standard deviation 0.019
Values 0.057 0.019 0.037
[54]
SNU475 DCN
Mean 3.92
Standard deviation 0.29
Values 3.7 4.1
[55]
THLE DCN
Mean 78.6
Standard deviation 48
Values 1.1e+02 44
[56]
liver DCN
Mean 54.1
Standard deviation 15
Values 60 51 70 35
[57]
ref_hepatocyte BGN
Mean 0.625
Standard deviation 0.62
Values 0.052 0 0.61 1.4 1
[58]
HepG2 BGN
Mean 5.39
Standard deviation 1.6
Values 6.5 4.3
[59]
HepG2.C3A BGN
Mean 0.127
Standard deviation 0.013
Values 0.14 0.12
[60]
HuH.7 BGN
Mean 0.0256
Standard deviation 0.029
Values 0.057 0.019 0
[61]
SNU475 BGN
Mean 3.94
Standard deviation 1.9
Values 2.6 5.3
[62]
THLE BGN
Mean 0.764
Standard deviation 0.37
Values 1 0.51
[63]
liver BGN
Mean 36.2
Standard deviation 29
Values 65 9.5 57 13
[64]
ref_hepatocyte VCAN
Mean 0.409
Standard deviation 0.32
Values 0.014 0.17 0.6 0.47 0.8
[65]
HepG2 VCAN
Mean 24.2
Standard deviation 5.2
Values 21 28
[66]
HepG2.C3A VCAN
Mean 0.601
Standard deviation 0.27
Values 0.41 0.79
[67]
HuH.7 VCAN
Mean 10
Standard deviation 9.3
Values 6.1 21 3.4
[68]
SNU475 VCAN
Mean 2.11
Standard deviation 1.7
Values 0.9 3.3
[69]
THLE VCAN
Mean 46.4
Standard deviation 11
Values 39 54
[70]
liver VCAN
Mean 8.26
Standard deviation 6.7
Values 4.5 8.5 2.4 18
[71]
ref_hepatocyte CSPG5
Mean 0.152
Standard deviation 0.19
Values 0 0.34 0 0.39 0.033
[72]
HepG2 CSPG5
Mean 0.145
Standard deviation 0.022
Values 0.16 0.13
[73]
HepG2.C3A CSPG5
Mean 0.0194
Standard deviation 0.027
Values 0.039 0
[74]
HuH.7 CSPG5
Mean 1.09
Standard deviation 0.56
Values 1.3 0.46 1.5
[75]
SNU475 CSPG5
Mean 0.62
Standard deviation 0.32
Values 0.39 0.85
[76]
THLE CSPG5
Mean 0.16
Standard deviation 0.016
Values 0.17 0.15
[77]
liver CSPG5
Mean 0.0462
Standard deviation 0.032
Values 0.024 0.043 0.026 0.093
[78]
ref_hepatocyte NCAN
Mean 0.0163
Standard deviation 0.036
Values 0 0 0.082 0 0
[79]
HepG2 NCAN
Mean 0.117
Standard deviation 0.12
Values 0.2 0.034
[80]
HepG2.C3A NCAN
Mean 0.0151
Standard deviation 0.0062
Values 0.019 0.011
[81]
HuH.7 NCAN
Mean 0.0731
Standard deviation 0.043
Values 0.041 0.12 0.056
[82]
SNU475 NCAN
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[83]
THLE NCAN
Mean 0.0207
Standard deviation 0.029
Values 0.041 0
[84]
liver NCAN
Mean 0.013
Standard deviation 0.015
Values 0.024 0.029 0 0
[85]
ref_hepatocyte CSPG4
Mean 0.0131
Standard deviation 0.018
Values 0.014 0 0.043 0 0.0081
[86]
HepG2 CSPG4
Mean 0.338
Standard deviation 0.09
Values 0.4 0.27
[87]
HepG2.C3A CSPG4
Mean 0.151
Standard deviation 0.062
Values 0.19 0.11
[88]
HuH.7 CSPG4
Mean 0.505
Standard deviation 0.16
Values 0.57 0.62 0.33
[89]
SNU475 CSPG4
Mean 3.45
Standard deviation 0.17
Values 3.6 3.3
[90]
THLE CSPG4
Mean 6.12
Standard deviation 2.4
Values 4.4 7.8
[91]
liver CSPG4
Mean 1.04
Standard deviation 1.2
Values 0.16 1.3 0.1 2.5
[92]
ref_hepatocyte BCAN
Mean 0.0065
Standard deviation 0.015
Values 0 0 0 0 0.033
[93]
HepG2 BCAN
Mean 4.23
Standard deviation 3.5
Values 6.7 1.8
[94]
HepG2.C3A BCAN
Mean 4.29
Standard deviation 0.91
Values 4.9 3.6
[95]
HuH.7 BCAN
Mean 1.21
Standard deviation 0.35
Values 1.3 1.5 0.83
[96]
SNU475 BCAN
Mean 1.96
Standard deviation 0.26
Values 2.1 1.8
[97]
THLE BCAN
Mean 0.527
Standard deviation 0.083
Values 0.59 0.47
[98]
liver BCAN
Mean 0.0604
Standard deviation 0.033
Values 0.071 0.029 0.1 0.04