REACTOME_CONSTITUTIVE_SIGNALING_BY_ABERRANT_PI3K_IN_CANCER Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 RAC1 Ras-related C3 botulinum toxin substrate 1 [1] -1.36[2] -1.83[3] -1.46[4] -0.61[5] -0.77[6] -2.18[7]
2 PTPN11 Tyrosine-protein phosphatase non-receptor type 11 [8] -0.52[9] -0.23[10] -0.62[11] 0.26[12] 0.75[13] 0.05[14]
3 GRB2 Growth factor receptor-bound protein 2 [15] 0.23[16] -0.08[17] -0.29[18] -0.07[19] -0.30[20] -0.91[21]
4 FGFR4 Fibroblast growth factor receptor 4 [22] 0.99[23] 1.19[24] 1.43[25] -4.86[26] -5.13[27] -0.71[28]
5 PIK3AP1 Phosphoinositide 3-kinase adapter protein 1 [29] -3.75[30] -1.53[31] -1.25[32] -3.56[33] -8.54[34] 1.29[35]
6 MET Hepatocyte growth factor receptor [36] -0.88[37] -0.99[38] -0.70[39] 0.91[40] -0.52[41] -0.24[42]
7 KLB Beta-klotho [43] -0.37[44] -0.68[45] 0.43[46] -6.59[47] -7.38[48] 0.34[49]
8 ERBB3 Receptor tyrosine-protein kinase erbB-3 [50] 1.04[51] 2.28[52] 0.98[53] -6.50[54] -6.39[55] 1.10[56]
9 FGFR3 Fibroblast growth factor receptor 3 [57] 1.77[58] 1.53[59] 1.52[60] -3.92[61] -2.72[62] -0.76[63]
10 RHOG Rho-related GTP-binding protein RhoG [64] -0.69[65] -2.02[66] -2.42[67] -0.60[68] -1.18[69] -1.91[70]
11 PIK3R1 Phosphatidylinositol 3-kinase regulatory subunit alpha [71] -1.43[72] -1.46[73] -0.71[74] 1.44[75] 0.80[76] 1.79[77]
12 ERBB2 Receptor tyrosine-protein kinase erbB-2 [78] 1.41[79] 0.09[80] 0.91[81] 0.63[82] 0.09[83] -1.06[84]
13 EGFR Epidermal growth factor receptor [85] -1.66[86] -2.18[87] 0.36[88] -0.19[89] 0.28[90] 1.44[91]
14 PIK3R2 Phosphatidylinositol 3-kinase regulatory subunit beta [92] 0.91[93] 0.99[94] 1.26[95] 0.08[96] 0.49[97] -1.50[98]
15 AREG Amphiregulin [99] -3.82[100] -7.21[101] -9.31[102] -10.32[103] -0.17[104] -11.52[105]
16 FGF2 Fibroblast growth factor 2 [106] -7.65[107] -7.54[108] -3.73[109] 0.31[110] 1.74[111] -2.88[112]
17 RAC2 Ras-related C3 botulinum toxin substrate 2 [113] -2.67[114] -8.81[115] -9.76[116] -2.01[117] 1.64[118] -2.44[119]
18 SRC Proto-oncogene tyrosine-protein kinase Src [120] 2.06[121] 1.90[122] 0.56[123] 1.77[124] 0.80[125] -2.06[126]
19 PIK3CB Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 0.25[127] 0.61[128] 0.43[129] 0.43[130] 0.44[131] -0.05[132]
20 IRS1 Insulin receptor substrate 1 [133] 1.13[134] 0.43[135] 1.51[136] 1.08[137] 0.51[138] 0.90[139]
21 IRS2 Insulin receptor substrate 2 [140] -6.61[141] [142] -4.24[143] -1.29[144] 2.39[145] 1.17[146]
22 FYN Tyrosine-protein kinase Fyn [147] -0.02[148] -8.77[149] -0.54[150] 0.85[151] 2.23[152] -0.24[153]
23 TGFA Protransforming growth factor alpha [154] 0.83[155] 1.75[156] -9.64[157] -1.59[158] -2.96[159] -1.60[160]
24 PIK3CA Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform -1.34[161] 0.15[162] 0.00[163] 0.50[164] 0.56[165] 0.70[166]
25 PIK3CD Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 0.92[167] 1.87[168] -2.29[169] -0.34[170] 0.27[171] -0.91[172]
26 HBEGF Proheparin-binding EGF-like growth factor [173] -1.95[174] -2.91[175] -4.32[176] -0.32[177] -0.78[178] -3.64[179]
27 FLT3LG Fms-related tyrosine kinase 3 ligand [180] -3.22[181] -3.27[182] -3.15[183] -2.96[184] -2.02[185] -3.37[186]
28 PDGFA Platelet-derived growth factor subunit A [187] -1.97[188] -1.90[189] -0.16[190] -0.97[191] -2.03[192] -1.96[193]
29 GAB2 GRB2-associated-binding protein 2 [194] 0.60[195] 0.24[196] 0.15[197] 0.30[198] 0.24[199] -0.67[200]
30 ESR1 Estrogen receptor [201] -8.26[202] [203] -7.24[204] -4.79[205] -7.20[206] 1.19[207]
31 FGFR2 Fibroblast growth factor receptor 2 [208] -3.47[209] -2.41[210] 1.19[211] 0.83[212] -4.16[213] 2.21[214]
32 NRG1 Pro-neuregulin-1, membrane-bound isoform [215] -0.63[216] -6.91[217] -4.36[218] 1.43[219] -6.20[220] -0.44[221]
33 FRS2 Fibroblast growth factor receptor substrate 2 [222] 0.33[223] 1.27[224] 1.43[225] 2.28[226] 1.76[227] 2.13[228]
34 STRN Striatin [229] 1.01[230] 1.82[231] 1.10[232] 2.70[233] 2.45[234] 1.69[235]
35 BTC Probetacellulin [236] -9.10[237] -9.64[238] -5.76[239] -3.50[240] -3.68[241] -4.13[242]
36 FGFR1 Fibroblast growth factor receptor 1 [243] 3.62[244] 1.78[245] 3.09[246] 4.43[247] 3.55[248] 0.45[249]
37 GAB1 GRB2-associated-binding protein 1 [250] 0.34[251] 1.28[252] 1.07[253] 1.31[254] 1.02[255] 1.66[256]
38 PDGFB Platelet-derived growth factor subunit B [257] 2.09[258] 1.81[259] -1.34[260] -0.56[261] -1.13[262] -0.84[263]
39 NRG4 Pro-neuregulin-4, membrane-bound isoform [264] -5.05[265] -2.32[266] -2.72[267] -0.34[268] -2.68[269] -2.15[270]
40 FGF7 Fibroblast growth factor 7 [271] -10.26[272] -6.70[273] [274] -6.00[275] -1.88[276] -2.66[277]
41 PDGFRA Platelet-derived growth factor receptor alpha [278] -4.58[279] -5.71[280] 1.59[281] -0.10[282] 4.43[283] 4.11[284]
42 PDGFRB Platelet-derived growth factor receptor beta [285] 0.34[286] 0.59[287] -2.21[288] 1.23[289] 1.64[290] 2.20[291]
43 VAV1 Proto-oncogene vav [292] -9.46[293] -4.78[294] -6.83[295] -6.71[296] -8.12[297] -0.03[298]
44 PIK3R3 Phosphatidylinositol 3-kinase regulatory subunit gamma [299] 0.76[300] 0.62[301] 1.13[302] 2.54[303] 1.41[304] 1.47[305]
45 CD86 T-lymphocyte activation antigen CD86 [306] [307] [308] -6.16[309] -4.72[310] -6.89[311] 0.14[312]
46 LCK Tyrosine-protein kinase Lck [313] 1.82[314] 1.75[315] -8.59[316] -5.71[317] -6.06[318] 0.02[319]
47 KL Klotho [320] -7.02[321] [322] [323] -2.02[324] -7.41[325] -0.96[326]
48 FGF5 Fibroblast growth factor 5 [327] -1.95[328] -0.78[329] -1.19[330] 0.86[331] 0.40[332] 1.92[333]
49 EREG Proepiregulin [334] 0.79[335] 0.57[336] -4.18[337] -2.19[338] 2.91[339] -2.69[340]
50 FGF1 Fibroblast growth factor 1 [341] -3.73[342] -3.08[343] -7.89[344] -0.04[345] 1.39[346] -1.17[347]
51 FGF19 Fibroblast growth factor 19 [348] -3.02[349] -2.02[350] 4.39[351] 0.21[352] -3.41[353] [354]
52 KITLG Kit ligand [355] 4.48[356] 0.56[357] 5.95[358] 6.11[359] 4.15[360] 1.83[361]
53 CD28 T-cell-specific surface glycoprotein CD28 [362] -4.96[363] -4.24[364] -4.55[365] -2.97[366] -3.17[367] -0.09[368]
54 KIT Mast/stem cell growth factor receptor Kit [369] -3.95[370] -5.98[371] [372] 1.88[373] -3.80[374] 2.43[375]
55 CD19 B-lymphocyte antigen CD19 [376] 1.15[377] 2.70[378] -2.48[379] -2.09[380] [381] -0.15[382]
56 CD80 T-lymphocyte activation antigen CD80 [383] [384] [385] -6.71[386] -1.78[387] -2.99[388] 1.41[389]
57 FLT3 Receptor-type tyrosine-protein kinase FLT3 [390] [391] [392] -4.95[393] -3.42[394] [395] 1.71[396]
58 ESR2 Estrogen receptor beta [397] -1.53[398] -1.30[399] -1.62[400] 0.01[401] -0.04[402] 1.32[403]
59 TRAT1 T-cell receptor-associated transmembrane adapter 1 [404] [405] [406] [407] [408] [409] 1.58[410]
60 ICOS Inducible T-cell costimulator [411] [412] -4.48[413] [414] [415] [416] -1.77[417]
61 HGF Hepatocyte growth factor [418] [419] [420] -3.10[421] 3.97[422] 0.85[423] 7.68[424]
62 FGF8 Fibroblast growth factor 8 [425] -4.29[426] -4.09[427] 0.06[428] -2.54[429] [430] 1.48[431]
63 FGF18 Fibroblast growth factor 18 [432] 0.82[433] -3.45[434] -1.61[435] -0.01[436] 0.44[437] -0.63[438]
64 FGF9 Fibroblast growth factor 9 [439] 1.30[440] -2.50[441] [442] 2.16[443] -3.10[444] -1.11[445]
65 EGF Pro-epidermal growth factor [446] 1.01[447] 2.65[448] 5.92[449] 8.40[450] 5.67[451] 0.37[452]
66 FGF17 Fibroblast growth factor 17 [453] [454] [455] [456] [457] [458] [459]
67 FGF22 Fibroblast growth factor 22 [460] [461] [462] [463] [464] [465] [466]
68 FGF10 Fibroblast growth factor 10 [467] [468] [469] [470] [471] [472] [473]
69 FGF20 Fibroblast growth factor 20 [474] [475] [476] [477] [478] [479] [480]
70 FGF23 Fibroblast growth factor 23 [481] [482] [483] [484] [485] [486] [487]
71 FGF3 Fibroblast growth factor 3 [488] [489] [490] [491] [492] [493] [494]
72 FGF16 Fibroblast growth factor 16 [495] [496] [497] [498] [499] [500] [501]
73 ERBB4 Receptor tyrosine-protein kinase erbB-4 [502] [503] [504] [505] [506] [507] [508]
74 FGF4 Fibroblast growth factor 4 [509] [510] [511] [512] [513] [514] [515]
75 NRG3 Pro-neuregulin-3, membrane-bound isoform [516] [517] [518] [519] [520] [521] [522]
76 NRG2 Pro-neuregulin-2, membrane-bound isoform [523] [524] [525] [526] [527] [528] [529]
77 FGF6 Fibroblast growth factor 6 [530] [531] [532] [533] [534] [535] [536]
78 EPGN Epigen [537] [538] [539] [540] [541] [542] [543]
[1]
ref_hepatocyte RAC1
Mean 52
Standard deviation 20
Values 28 59 81 45 47
[2]
HepG2 RAC1
Mean 87.4
Standard deviation 1.9
Values 89 86
[3]
HepG2.C3A RAC1
Mean 62
Standard deviation 7.4
Values 67 57
[4]
HuH.7 RAC1
Mean 97.2
Standard deviation 9.7
Values 1e+02 86 1e+02
[5]
SNU475 RAC1
Mean 96.5
Standard deviation 10
Values 89 1e+02
[6]
THLE RAC1
Mean 107
Standard deviation 19
Values 94 1.2e+02
[7]
liver RAC1
Mean 37.8
Standard deviation 32
Values 63 12 67 9.5
[8]
ref_hepatocyte PTPN11
Mean 22.2
Standard deviation 20
Values 33 53 10 7.5 7.4
[9]
HepG2 PTPN11
Mean 66.7
Standard deviation 12
Values 58 76
[10]
HepG2.C3A PTPN11
Mean 80.2
Standard deviation 17
Values 68 92
[11]
HuH.7 PTPN11
Mean 74.5
Standard deviation 12
Values 86 77 61
[12]
SNU475 PTPN11
Mean 75.4
Standard deviation 0.72
Values 75 76
[13]
THLE PTPN11
Mean 131
Standard deviation 5.1
Values 1.3e+02 1.3e+02
[14]
liver PTPN11
Mean 75.4
Standard deviation 18
Values 60 99 62 80
[15]
ref_hepatocyte GRB2
Mean 20.7
Standard deviation 5.5
Values 27 26 20 14 17
[16]
HepG2 GRB2
Mean 104
Standard deviation 4.7
Values 1e+02 1.1e+02
[17]
HepG2.C3A GRB2
Mean 83.1
Standard deviation 0.44
Values 83 83
[18]
HuH.7 GRB2
Mean 86.7
Standard deviation 7.6
Values 89 78 93
[19]
SNU475 GRB2
Mean 55.7
Standard deviation 1.4
Values 55 57
[20]
THLE GRB2
Mean 58.8
Standard deviation 3.7
Values 56 61
[21]
liver GRB2
Mean 36.1
Standard deviation 16
Values 50 22 50 22
[22]
ref_hepatocyte FGFR4
Mean 15.1
Standard deviation 12
Values 30 2.5 2.2 18 23
[23]
HepG2 FGFR4
Mean 129
Standard deviation 13
Values 1.2e+02 1.4e+02
[24]
HepG2.C3A FGFR4
Mean 146
Standard deviation 22
Values 1.6e+02 1.3e+02
[25]
HuH.7 FGFR4
Mean 209
Standard deviation 68
Values 2.4e+02 1.3e+02 2.5e+02
[26]
SNU475 FGFR4
Mean 1.47
Standard deviation 0.43
Values 1.2 1.8
[27]
THLE FGFR4
Mean 1.51
Standard deviation 0.45
Values 1.8 1.2
[28]
liver FGFR4
Mean 30.3
Standard deviation 10
Values 43 18 31 29
[29]
ref_hepatocyte PIK3AP1
Mean 13.4
Standard deviation 11
Values 1.4 7.1 11 20 28
[30]
HepG2 PIK3AP1
Mean 4.31
Standard deviation 2.2
Values 2.7 5.9
[31]
HepG2.C3A PIK3AP1
Mean 19.8
Standard deviation 2.9
Values 18 22
[32]
HuH.7 PIK3AP1
Mean 29.2
Standard deviation 4.3
Values 34 26 27
[33]
SNU475 PIK3AP1
Mean 3.24
Standard deviation 0.93
Values 3.9 2.6
[34]
THLE PIK3AP1
Mean 0.127
Standard deviation 0.046
Values 0.095 0.16
[35]
liver PIK3AP1
Mean 108
Standard deviation 35
Values 61 1.4e+02 1.1e+02 1.2e+02
[36]
ref_hepatocyte MET
Mean 12.9
Standard deviation 12
Values 6.9 32 16 3.7 5.7
[37]
HepG2 MET
Mean 30.2
Standard deviation 2.7
Values 32 28
[38]
HepG2.C3A MET
Mean 27.5
Standard deviation 6.5
Values 23 32
[39]
HuH.7 MET
Mean 40.8
Standard deviation 7.3
Values 43 47 33
[40]
SNU475 MET
Mean 68.7
Standard deviation 7.1
Values 64 74
[41]
THLE MET
Mean 31.7
Standard deviation 2
Values 33 30
[42]
liver MET
Mean 35.9
Standard deviation 13
Values 27 46 22 48
[43]
ref_hepatocyte KLB
Mean 9.92
Standard deviation 12
Values 30 1.9 0.71 6.7 9.9
[44]
HepG2 KLB
Mean 33.1
Standard deviation 23
Values 17 49
[45]
HepG2.C3A KLB
Mean 26.3
Standard deviation 0.12
Values 26 26
[46]
HuH.7 KLB
Mean 68.9
Standard deviation 30
Values 57 1e+02 46
[47]
SNU475 KLB
Mean 0.292
Standard deviation 0.04
Values 0.32 0.26
[48]
THLE KLB
Mean 0.21
Standard deviation 0.004
Values 0.21 0.21
[49]
liver KLB
Mean 41.2
Standard deviation 7.6
Values 52 37 40 36
[50]
ref_hepatocyte ERBB3
Mean 8.22
Standard deviation 4
Values 12 3.8 4.1 11 10
[51]
HepG2 ERBB3
Mean 72.9
Standard deviation 2.6
Values 75 71
[52]
HepG2.C3A ERBB3
Mean 169
Standard deviation 42
Values 2e+02 1.4e+02
[53]
HuH.7 ERBB3
Mean 83.4
Standard deviation 7.8
Values 92 80 78
[54]
SNU475 ERBB3
Mean 0.258
Standard deviation 0.12
Values 0.18 0.34
[55]
THLE ERBB3
Mean 0.344
Standard deviation 0.05
Values 0.38 0.31
[56]
liver ERBB3
Mean 57.8
Standard deviation 20
Values 44 71 39 79
[57]
ref_hepatocyte FGFR3
Mean 7.46
Standard deviation 9.2
Values 23 2.7 0.18 4.6 6.4
[58]
HepG2 FGFR3
Mean 109
Standard deviation 1.1
Values 1.1e+02 1.1e+02
[59]
HepG2.C3A FGFR3
Mean 91.5
Standard deviation 12
Values 1e+02 83
[60]
HuH.7 FGFR3
Mean 110
Standard deviation 12
Values 1.2e+02 97 1.2e+02
[61]
SNU475 FGFR3
Mean 1.4
Standard deviation 0.25
Values 1.6 1.2
[62]
THLE FGFR3
Mean 3.99
Standard deviation 0.31
Values 3.8 4.2
[63]
liver FGFR3
Mean 14.5
Standard deviation 8.7
Values 9.3 18 5.8 25
[64]
ref_hepatocyte RHOG
Mean 7.46
Standard deviation 3.9
Values 2.6 4.7 11 11 7.4
[65]
HepG2 RHOG
Mean 19.8
Standard deviation 1.5
Values 21 19
[66]
HepG2.C3A RHOG
Mean 7.77
Standard deviation 0.56
Values 8.2 7.4
[67]
HuH.7 RHOG
Mean 7.15
Standard deviation 1.1
Values 8.1 5.9 7.5
[68]
SNU475 RHOG
Mean 14
Standard deviation 0.77
Values 13 14
[69]
THLE RHOG
Mean 11.6
Standard deviation 2.4
Values 9.9 13
[70]
liver RHOG
Mean 6.51
Standard deviation 5.8
Values 13 1.6 10 1.6
[71]
ref_hepatocyte PIK3R1
Mean 7.45
Standard deviation 3.9
Values 4.1 7.4 4.2 8.1 14
[72]
HepG2 PIK3R1
Mean 11.9
Standard deviation 3
Values 9.8 14
[73]
HepG2.C3A PIK3R1
Mean 11.5
Standard deviation 2.6
Values 9.6 13
[74]
HuH.7 PIK3R1
Mean 23.4
Standard deviation 8.6
Values 23 32 15
[75]
SNU475 PIK3R1
Mean 57.3
Standard deviation 32
Values 80 35
[76]
THLE PIK3R1
Mean 45.5
Standard deviation 1.5
Values 44 47
[77]
liver PIK3R1
Mean 84.8
Standard deviation 47
Values 64 1e+02 32 1.4e+02
[78]
ref_hepatocyte ERBB2
Mean 6.44
Standard deviation 3.8
Values 13 3.9 4.7 3.7 7.1
[79]
HepG2 ERBB2
Mean 73.6
Standard deviation 10
Values 66 81
[80]
HepG2.C3A ERBB2
Mean 29
Standard deviation 6.9
Values 34 24
[81]
HuH.7 ERBB2
Mean 62.5
Standard deviation 7.1
Values 69 55 63
[82]
SNU475 ERBB2
Mean 28.2
Standard deviation 8.4
Values 34 22
[83]
THLE ERBB2
Mean 24.1
Standard deviation 2.7
Values 22 26
[84]
liver ERBB2
Mean 10.2
Standard deviation 3.4
Values 7.9 8.1 9.6 15
[85]
ref_hepatocyte EGFR
Mean 5.53
Standard deviation 4.2
Values 0.94 8.5 11 3.5 3.5
[86]
HepG2 EGFR
Mean 7.53
Standard deviation 0.89
Values 6.9 8.2
[87]
HepG2.C3A EGFR
Mean 5.18
Standard deviation 0.67
Values 5.7 4.7
[88]
HuH.7 EGFR
Mean 36.6
Standard deviation 25
Values 32 63 15
[89]
SNU475 EGFR
Mean 13.7
Standard deviation 0.74
Values 13 14
[90]
THLE EGFR
Mean 23.6
Standard deviation 4.4
Values 20 27
[91]
liver EGFR
Mean 49.4
Standard deviation 14
Values 39 69 47 42
[92]
ref_hepatocyte PIK3R2
Mean 5.25
Standard deviation 3.4
Values 11 3.2 3.1 4.9 3.8
[93]
HepG2 PIK3R2
Mean 42.5
Standard deviation 2.8
Values 44 41
[94]
HepG2.C3A PIK3R2
Mean 44.2
Standard deviation 13
Values 53 35
[95]
HuH.7 PIK3R2
Mean 64.7
Standard deviation 10
Values 75 55 64
[96]
SNU475 PIK3R2
Mean 15.7
Standard deviation 3.3
Values 18 13
[97]
THLE PIK3R2
Mean 26
Standard deviation 2.8
Values 24 28
[98]
liver PIK3R2
Mean 6.1
Standard deviation 1.7
Values 7.6 6 3.8 6.9
[99]
ref_hepatocyte AREG
Mean 5.24
Standard deviation 9.3
Values 1.7 22 1.7 0.57 0.4
[100]
HepG2 AREG
Mean 1.59
Standard deviation 1.3
Values 2.5 0.67
[101]
HepG2.C3A AREG
Mean 0.15
Standard deviation 0.061
Values 0.11 0.19
[102]
HuH.7 AREG
Mean 0.0425
Standard deviation 0.021
Values 0.057 0.051 0.019
[103]
SNU475 AREG
Mean 0.0116
Standard deviation 0.016
Values 0.023 0
[104]
THLE AREG
Mean 16.4
Standard deviation 1.7
Values 15 18
[105]
liver AREG
Mean 0.00588
Standard deviation 0.012
Values 0.024 0 0 0
[106]
ref_hepatocyte FGF2
Mean 4.04
Standard deviation 6.5
Values 0.052 15 3.7 0.37 0.73
[107]
HepG2 FGF2
Mean 0.0866
Standard deviation 0.08
Values 0.14 0.03
[108]
HepG2.C3A FGF2
Mean 0.092
Standard deviation 0.0064
Values 0.087 0.097
[109]
HuH.7 FGF2
Mean 1.57
Standard deviation 0.89
Values 0.98 2.6 1.1
[110]
SNU475 FGF2
Mean 14.2
Standard deviation 1.3
Values 13 15
[111]
THLE FGF2
Mean 47.5
Standard deviation 0.66
Values 48 47
[112]
liver FGF2
Mean 1.81
Standard deviation 0.66
Values 1.9 2.5 0.9 2
[113]
ref_hepatocyte RAC2
Mean 3.71
Standard deviation 4.6
Values 0 0.72 11 1.6 5.1
[114]
HepG2 RAC2
Mean 2.5
Standard deviation 2.1
Values 4 1
[115]
HepG2.C3A RAC2
Mean 0.035
Standard deviation 0.019
Values 0.049 0.021
[116]
HuH.7 RAC2
Mean 0.0221
Standard deviation 0.018
Values 0.041 0.0064 0.019
[117]
SNU475 RAC2
Mean 2.6
Standard deviation 0.081
Values 2.5 2.7
[118]
THLE RAC2
Mean 40.7
Standard deviation 12
Values 32 49
[119]
liver RAC2
Mean 2.24
Standard deviation 1.8
Values 3.9 0.44 3.7 0.86
[120]
ref_hepatocyte SRC
Mean 3.67
Standard deviation 3.6
Values 9.6 4.7 2.2 0.77 1.2
[121]
HepG2 SRC
Mean 66
Standard deviation 21
Values 81 51
[122]
HepG2.C3A SRC
Mean 58.1
Standard deviation 18
Values 71 45
[123]
HuH.7 SRC
Mean 27.9
Standard deviation 2
Values 28 29 26
[124]
SNU475 SRC
Mean 35.6
Standard deviation 3.5
Values 38 33
[125]
THLE SRC
Mean 22.5
Standard deviation 2.7
Values 21 24
[126]
liver SRC
Mean 2.9
Standard deviation 1
Values 4.1 2.5 1.7 3.2
[127]
ref_hepatocyte PIK3CB
Mean 3.18
Standard deviation 1.5
Values 5.2 4.2 2.6 1.8 2.1
[128]
HepG2 PIK3CB
Mean 16.3
Standard deviation 2.1
Values 15 18
[129]
HepG2.C3A PIK3CB
Mean 20.6
Standard deviation 2.7
Values 23 19
[130]
HuH.7 PIK3CB
Mean 22.1
Standard deviation 2.1
Values 24 23 20
[131]
SNU475 PIK3CB
Mean 12.1
Standard deviation 2.7
Values 14 10
[132]
THLE PIK3CB
Mean 15.1
Standard deviation 0.94
Values 14 16
[133]
liver PIK3CB
Mean 10.1
Standard deviation 3.7
Values 6.4 15 7.9 11
[134]
ref_hepatocyte IRS1
Mean 3.05
Standard deviation 1.4
Values 4.3 1.5 2.7 2.1 4.7
[135]
HepG2 IRS1
Mean 28.7
Standard deviation 8.6
Values 35 23
[136]
HepG2.C3A IRS1
Mean 17.4
Standard deviation 6
Values 22 13
[137]
HuH.7 IRS1
Mean 44.8
Standard deviation 6.6
Values 49 48 37
[138]
SNU475 IRS1
Mean 18.3
Standard deviation 5.2
Values 15 22
[139]
THLE IRS1
Mean 15.3
Standard deviation 0.24
Values 15 15
[140]
liver IRS1
Mean 18.8
Standard deviation 4.8
Values 23 18 12 22
[141]
ref_hepatocyte IRS2
Mean 2.12
Standard deviation 2.3
Values 0.019 0.61 1.4 5.7 2.9
[142]
HepG2 IRS2
Mean 0.0931
Standard deviation 0.071
Values 0.14 0.043
[143]
HepG2.C3A IRS2
Mean 0
Standard deviation 0
Values 0 0
[144]
HuH.7 IRS2
Mean 0.575
Standard deviation 0.68
Values 0.2 1.4 0.17
[145]
SNU475 IRS2
Mean 2.45
Standard deviation 0.45
Values 2.1 2.8
[146]
THLE IRS2
Mean 39
Standard deviation 5.9
Values 35 43
[147]
liver IRS2
Mean 15.7
Standard deviation 9.9
Values 29 11 6.3 17
[148]
ref_hepatocyte FYN
Mean 2.1
Standard deviation 2.2
Values 2.2 0.039 0.23 2.6 5.5
[149]
HepG2 FYN
Mean 8.91
Standard deviation 0.7
Values 9.4 8.4
[150]
HepG2.C3A FYN
Mean 0.0204
Standard deviation 0.0014
Values 0.019 0.021
[151]
HuH.7 FYN
Mean 7.43
Standard deviation 2.2
Values 8.9 4.8 8.5
[152]
SNU475 FYN
Mean 10.7
Standard deviation 2.5
Values 12 8.9
[153]
THLE FYN
Mean 34.5
Standard deviation 4.9
Values 38 31
[154]
liver FYN
Mean 5.84
Standard deviation 2.1
Values 8.9 4.4 5.1 5
[155]
ref_hepatocyte TGFA
Mean 2
Standard deviation 1.3
Values 3.8 2.7 2.1 0.72 0.76
[156]
HepG2 TGFA
Mean 15.3
Standard deviation 2.1
Values 17 14
[157]
HepG2.C3A TGFA
Mean 28.4
Standard deviation 4.2
Values 25 31
[158]
HuH.7 TGFA
Mean 0.0129
Standard deviation 0.0035
Values 0.016 0.013 0.0094
[159]
SNU475 TGFA
Mean 1.88
Standard deviation 0.53
Values 1.5 2.3
[160]
THLE TGFA
Mean 0.903
Standard deviation 0.47
Values 1.2 0.57
[161]
liver TGFA
Mean 2.16
Standard deviation 0.15
Values 2.1 2.3 2.2 2
[162]
ref_hepatocyte PIK3CA
Mean 1.87
Standard deviation 0.73
Values 2.3 2.6 2.3 1.2 0.94
[163]
HepG2 PIK3CA
Mean 3.17
Standard deviation 1.6
Values 2.1 4.3
[164]
HepG2.C3A PIK3CA
Mean 8.78
Standard deviation 1.1
Values 8 9.6
[165]
HuH.7 PIK3CA
Mean 9.59
Standard deviation 2.4
Values 10 12 7
[166]
SNU475 PIK3CA
Mean 7.49
Standard deviation 0.93
Values 8.1 6.8
[167]
THLE PIK3CA
Mean 9.67
Standard deviation 0.66
Values 10 9.2
[168]
liver PIK3CA
Mean 9.99
Standard deviation 4.7
Values 6.1 15 6 13
[169]
ref_hepatocyte PIK3CD
Mean 1.86
Standard deviation 1.7
Values 4.1 0.94 3.3 0.38 0.66
[170]
HepG2 PIK3CD
Mean 15.2
Standard deviation 3.8
Values 18 13
[171]
HepG2.C3A PIK3CD
Mean 28.8
Standard deviation 2.6
Values 31 27
[172]
HuH.7 PIK3CD
Mean 1.97
Standard deviation 0.32
Values 2 2.3 1.6
[173]
SNU475 PIK3CD
Mean 4.15
Standard deviation 0.57
Values 4.6 3.7
[174]
THLE PIK3CD
Mean 7.91
Standard deviation 1.1
Values 7.1 8.7
[175]
liver PIK3CD
Mean 3.25
Standard deviation 1.3
Values 2.4 3 2.6 5.1
[176]
ref_hepatocyte HBEGF
Mean 1.81
Standard deviation 1.5
Values 1 3.1 3.8 0.78 0.34
[177]
HepG2 HBEGF
Mean 2.02
Standard deviation 0.16
Values 2.1 1.9
[178]
HepG2.C3A HBEGF
Mean 1.02
Standard deviation 0.3
Values 1.2 0.82
[179]
HuH.7 HBEGF
Mean 0.469
Standard deviation 0.044
Values 0.52 0.43 0.46
[180]
SNU475 HBEGF
Mean 4.11
Standard deviation 0.34
Values 3.9 4.4
[181]
THLE HBEGF
Mean 3.71
Standard deviation 0.17
Values 3.8 3.6
[182]
liver HBEGF
Mean 0.478
Standard deviation 0.29
Values 0.89 0.27 0.28 0.46
[183]
ref_hepatocyte FLT3LG
Mean 1.73
Standard deviation 1.8
Values 0 0 4.1 1.9 2.7
[184]
HepG2 FLT3LG
Mean 0.799
Standard deviation 0.045
Values 0.83 0.77
[185]
HepG2.C3A FLT3LG
Mean 0.761
Standard deviation 0.27
Values 0.95 0.57
[186]
HuH.7 FLT3LG
Mean 1.01
Standard deviation 0.09
Values 1 1.1 0.92
[187]
SNU475 FLT3LG
Mean 0.629
Standard deviation 0.022
Values 0.64 0.61
[188]
THLE FLT3LG
Mean 1.5
Standard deviation 0.22
Values 1.7 1.3
[189]
liver FLT3LG
Mean 0.55
Standard deviation 0.58
Values 1.3 0.1 0.62 0.15
[190]
ref_hepatocyte PDGFA
Mean 1.67
Standard deviation 1.7
Values 0.21 1.9 4.5 1.6 0.2
[191]
HepG2 PDGFA
Mean 1.84
Standard deviation 0.32
Values 2.1 1.6
[192]
HepG2.C3A PDGFA
Mean 1.9
Standard deviation 0.64
Values 2.4 1.4
[193]
HuH.7 PDGFA
Mean 7.72
Standard deviation 1.4
Values 7.9 9 6.2
[194]
SNU475 PDGFA
Mean 2.43
Standard deviation 0.11
Values 2.5 2.3
[195]
THLE PDGFA
Mean 1.44
Standard deviation 0.18
Values 1.3 1.6
[196]
liver PDGFA
Mean 1.41
Standard deviation 0.21
Values 1.3 1.4 1.7 1.2
[197]
ref_hepatocyte GAB2
Mean 1.62
Standard deviation 1.7
Values 1.2 1.9 4.5 0.25 0.31
[198]
HepG2 GAB2
Mean 10.6
Standard deviation 4.9
Values 14 7.1
[199]
HepG2.C3A GAB2
Mean 8.12
Standard deviation 3.2
Values 10 5.9
[200]
HuH.7 GAB2
Mean 9.24
Standard deviation 2.5
Values 9.6 12 6.6
[201]
SNU475 GAB2
Mean 5.63
Standard deviation 0.73
Values 6.1 5.1
[202]
THLE GAB2
Mean 6.7
Standard deviation 0.57
Values 7.1 6.3
[203]
liver GAB2
Mean 3.35
Standard deviation 1.3
Values 2.8 4.2 1.8 4.6
[204]
ref_hepatocyte ESR1
Mean 1.54
Standard deviation 2.3
Values 0 0.17 0 2.2 5.3
[205]
HepG2 ESR1
Mean 0.0215
Standard deviation 0.018
Values 0.034 0.0086
[206]
HepG2.C3A ESR1
Mean 0
Standard deviation 0
Values 0 0
[207]
HuH.7 ESR1
Mean 0.0525
Standard deviation 0.047
Values 0.11 0.032 0.019
[208]
SNU475 ESR1
Mean 0.157
Standard deviation 0.14
Values 0.06 0.25
[209]
THLE ESR1
Mean 0.0367
Standard deviation 0.0067
Values 0.041 0.032
[210]
liver ESR1
Mean 11.5
Standard deviation 7
Values 7.2 11 6.1 22
[211]
ref_hepatocyte FGFR2
Mean 1.34
Standard deviation 1.4
Values 0.47 0.46 0.084 2.4 3.2
[212]
HepG2 FGFR2
Mean 0.519
Standard deviation 0.3
Values 0.3 0.73
[213]
HepG2.C3A FGFR2
Mean 1.07
Standard deviation 0.3
Values 0.86 1.3
[214]
HuH.7 FGFR2
Mean 15.7
Standard deviation 0.71
Values 16 15 16
[215]
SNU475 FGFR2
Mean 6.74
Standard deviation 6.4
Values 11 2.2
[216]
THLE FGFR2
Mean 0.263
Standard deviation 0.0039
Values 0.27 0.26
[217]
liver FGFR2
Mean 20.4
Standard deviation 8
Values 18 19 13 32
[218]
ref_hepatocyte NRG1
Mean 1.2
Standard deviation 1
Values 0 1 2.8 1.5 0.74
[219]
HepG2 NRG1
Mean 3.35
Standard deviation 2.7
Values 1.4 5.3
[220]
HepG2.C3A NRG1
Mean 0.0424
Standard deviation 0.046
Values 0.0097 0.075
[221]
HuH.7 NRG1
Mean 0.302
Standard deviation 0.17
Values 0.16 0.49 0.25
[222]
SNU475 NRG1
Mean 9.16
Standard deviation 3.3
Values 12 6.8
[223]
THLE NRG1
Mean 0.0576
Standard deviation 0.031
Values 0.035 0.08
[224]
liver NRG1
Mean 2.92
Standard deviation 2.1
Values 1.2 5.5 3.6 1.2
[225]
ref_hepatocyte FRS2
Mean 1.15
Standard deviation 0.48
Values 1.3 1.9 0.69 0.74 1.2
[226]
HepG2 FRS2
Mean 6.18
Standard deviation 3
Values 4 8.3
[227]
HepG2.C3A FRS2
Mean 11.7
Standard deviation 4
Values 8.9 15
[228]
HuH.7 FRS2
Mean 15.9
Standard deviation 4.9
Values 16 21 11
[229]
SNU475 FRS2
Mean 15.7
Standard deviation 0.35
Values 16 15
[230]
THLE FRS2
Mean 13.6
Standard deviation 0.96
Values 14 13
[231]
liver FRS2
Mean 16.5
Standard deviation 3.3
Values 18 20 13 15
[232]
ref_hepatocyte STRN
Mean 1.09
Standard deviation 0.66
Values 1 1.8 1.7 0.36 0.54
[233]
HepG2 STRN
Mean 9.37
Standard deviation 2.4
Values 7.7 11
[234]
HepG2.C3A STRN
Mean 16.3
Standard deviation 1.3
Values 15 17
[235]
HuH.7 STRN
Mean 12
Standard deviation 3.1
Values 14 14 8.4
[236]
SNU475 STRN
Mean 20
Standard deviation 0.35
Values 20 20
[237]
THLE STRN
Mean 20.8
Standard deviation 0.87
Values 20 21
[238]
liver STRN
Mean 11.5
Standard deviation 5
Values 9.4 16 5.4 15
[239]
ref_hepatocyte BTC
Mean 0.915
Standard deviation 1.9
Values 0 4.4 0.079 0 0.12
[240]
HepG2 BTC
Mean 0.00716
Standard deviation 0.002
Values 0.0057 0.0086
[241]
HepG2.C3A BTC
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[242]
HuH.7 BTC
Mean 0.087
Standard deviation 0.09
Values 0.066 0.19 0.0094
[243]
SNU475 BTC
Mean 0.229
Standard deviation 0.03
Values 0.25 0.21
[244]
THLE BTC
Mean 0.251
Standard deviation 0.13
Values 0.34 0.16
[245]
liver BTC
Mean 0.172
Standard deviation 0.058
Values 0.21 0.23 0.1 0.15
[246]
ref_hepatocyte FGFR1
Mean 0.81
Standard deviation 0.63
Values 1.2 0.49 1.6 0.06 0.62
[247]
HepG2 FGFR1
Mean 42.7
Standard deviation 4
Values 40 46
[248]
HepG2.C3A FGFR1
Mean 11.8
Standard deviation 3.5
Values 9.3 14
[249]
HuH.7 FGFR1
Mean 35.6
Standard deviation 13
Values 43 20 43
[250]
SNU475 FGFR1
Mean 49.5
Standard deviation 1.4
Values 50 49
[251]
THLE FGFR1
Mean 33.4
Standard deviation 3.3
Values 36 31
[252]
liver FGFR1
Mean 3.64
Standard deviation 0.67
Values 3 4.2 3.2 4.3
[253]
ref_hepatocyte GAB1
Mean 0.787
Standard deviation 0.67
Values 2 0.61 0.33 0.38 0.66
[254]
HepG2 GAB1
Mean 4.28
Standard deviation 2.2
Values 2.8 5.8
[255]
HepG2.C3A GAB1
Mean 8.12
Standard deviation 2.3
Values 6.5 9.8
[256]
HuH.7 GAB1
Mean 8.48
Standard deviation 1.4
Values 10 8.1 7.3
[257]
SNU475 GAB1
Mean 5.52
Standard deviation 1.6
Values 6.6 4.4
[258]
THLE GAB1
Mean 5.62
Standard deviation 0.39
Values 5.9 5.3
[259]
liver GAB1
Mean 8.2
Standard deviation 2.5
Values 7.1 10 5.3 10
[260]
ref_hepatocyte PDGFB
Mean 0.738
Standard deviation 0.56
Values 0.25 1.4 1.3 0.23 0.54
[261]
HepG2 PDGFB
Mean 13.6
Standard deviation 5.2
Values 17 9.9
[262]
HepG2.C3A PDGFB
Mean 11
Standard deviation 4.6
Values 14 7.7
[263]
HuH.7 PDGFB
Mean 1.5
Standard deviation 0.44
Values 1.1 2 1.5
[264]
SNU475 PDGFB
Mean 1.42
Standard deviation 0.33
Values 1.7 1.2
[265]
THLE PDGFB
Mean 1.18
Standard deviation 0.022
Values 1.2 1.2
[266]
liver PDGFB
Mean 1.36
Standard deviation 0.68
Values 0.4 2 1.7 1.4
[267]
ref_hepatocyte NRG4
Mean 0.631
Standard deviation 0.35
Values 0 0.75 0.81 0.78 0.81
[268]
HepG2 NRG4
Mean 0.0816
Standard deviation 0.03
Values 0.1 0.06
[269]
HepG2.C3A NRG4
Mean 0.534
Standard deviation 0.042
Values 0.56 0.5
[270]
HuH.7 NRG4
Mean 0.494
Standard deviation 0.053
Values 0.43 0.51 0.53
[271]
SNU475 NRG4
Mean 1.41
Standard deviation 0.46
Values 1.7 1.1
[272]
THLE NRG4
Mean 0.345
Standard deviation 0.16
Values 0.46 0.23
[273]
liver NRG4
Mean 0.468
Standard deviation 0.12
Values 0.45 0.41 0.64 0.37
[274]
ref_hepatocyte FGF7
Mean 0.61
Standard deviation 0.64
Values 0 0.3 0.46 0.6 1.7
[275]
HepG2 FGF7
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[276]
HepG2.C3A FGF7
Mean 0.0248
Standard deviation 0.02
Values 0.039 0.011
[277]
HuH.7 FGF7
Mean 0
Standard deviation 0
Values 0 0 0
[278]
SNU475 FGF7
Mean 0.027
Standard deviation 0.012
Values 0.019 0.035
[279]
THLE FGF7
Mean 0.584
Standard deviation 0.1
Values 0.66 0.51
[280]
liver FGF7
Mean 0.317
Standard deviation 0.15
Values 0.28 0.31 0.51 0.16
[281]
ref_hepatocyte PDGFRA
Mean 0.51
Standard deviation 0.67
Values 0 0.018 1.5 0.93 0.11
[282]
HepG2 PDGFRA
Mean 0.0916
Standard deviation 0.016
Values 0.08 0.1
[283]
HepG2.C3A PDGFRA
Mean 0.0414
Standard deviation 0.017
Values 0.029 0.054
[284]
HuH.7 PDGFRA
Mean 7.89
Standard deviation 0.88
Values 8.3 8.5 6.9
[285]
SNU475 PDGFRA
Mean 1.35
Standard deviation 1.4
Values 0.38 2.3
[286]
THLE PDGFRA
Mean 38.6
Standard deviation 7.6
Values 33 44
[287]
liver PDGFRA
Mean 28.9
Standard deviation 13
Values 23 35 15 43
[288]
ref_hepatocyte PDGFRB
Mean 0.484
Standard deviation 0.34
Values 0.12 0.23 0.58 0.98 0.51
[289]
HepG2 PDGFRB
Mean 2.63
Standard deviation 0.88
Values 2 3.3
[290]
HepG2.C3A PDGFRB
Mean 3.08
Standard deviation 0.099
Values 3 3.2
[291]
HuH.7 PDGFRB
Mean 0.54
Standard deviation 0.088
Values 0.61 0.57 0.44
[292]
SNU475 PDGFRB
Mean 3.21
Standard deviation 0.1
Values 3.1 3.3
[293]
THLE PDGFRB
Mean 5.3
Standard deviation 0.27
Values 5.1 5.5
[294]
liver PDGFRB
Mean 7.32
Standard deviation 2
Values 6.9 6.3 5.8 10
[295]
ref_hepatocyte VAV1
Mean 0.469
Standard deviation 0.4
Values 0 0.2 0.63 0.48 1
[296]
HepG2 VAV1
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[297]
HepG2.C3A VAV1
Mean 0.0726
Standard deviation 0.034
Values 0.049 0.097
[298]
HuH.7 VAV1
Mean 0.0213
Standard deviation 0.0061
Values 0.016 0.019 0.028
[299]
SNU475 VAV1
Mean 0.0127
Standard deviation 0.018
Values 0 0.025
[300]
THLE VAV1
Mean 0.00592
Standard deviation 0.0084
Values 0.012 0
[301]
liver VAV1
Mean 1.51
Standard deviation 0.9
Values 0.75 1.8 0.82 2.6
[302]
ref_hepatocyte PIK3R3
Mean 0.405
Standard deviation 0.3
Values 0.52 0.81 0.47 0.078 0.15
[303]
HepG2 PIK3R3
Mean 2.95
Standard deviation 2.5
Values 1.2 4.7
[304]
HepG2.C3A PIK3R3
Mean 2.65
Standard deviation 1.6
Values 1.5 3.8
[305]
HuH.7 PIK3R3
Mean 4.56
Standard deviation 1.3
Values 5.7 3.1 5
[306]
SNU475 PIK3R3
Mean 6.68
Standard deviation 0.22
Values 6.5 6.8
[307]
THLE PIK3R3
Mean 3.8
Standard deviation 0.9
Values 3.2 4.4
[308]
liver PIK3R3
Mean 3.68
Standard deviation 0.27
Values 3.7 3.8 3.3 4
[309]
ref_hepatocyte CD86
Mean 0.389
Standard deviation 0.38
Values 0 0 0.61 0.48 0.85
[310]
HepG2 CD86
Mean 0
Standard deviation 0
Values 0 0
[311]
HepG2.C3A CD86
Mean 0
Standard deviation 0
Values 0 0
[312]
HuH.7 CD86
Mean 0.0281
Standard deviation 0.02
Values 0.049 0.026 0.0094
[313]
SNU475 CD86
Mean 0.0418
Standard deviation 0.02
Values 0.028 0.056
[314]
THLE CD86
Mean 0.0115
Standard deviation 0.0088
Values 0.018 0.0053
[315]
liver CD86
Mean 1.41
Standard deviation 0.3
Values 1.2 1.9 1.2 1.3
[316]
ref_hepatocyte LCK
Mean 0.319
Standard deviation 0.43
Values 0.11 0 0.49 0 0.99
[317]
HepG2 LCK
Mean 4.84
Standard deviation 4.4
Values 8 1.7
[318]
HepG2.C3A LCK
Mean 4.55
Standard deviation 0.16
Values 4.4 4.7
[319]
HuH.7 LCK
Mean 0.00428
Standard deviation 0.0074
Values 0 0.013 0
[320]
SNU475 LCK
Mean 0.0173
Standard deviation 0.011
Values 0.0093 0.025
[321]
THLE LCK
Mean 0.0169
Standard deviation 0.0013
Values 0.018 0.016
[322]
liver LCK
Mean 1.07
Standard deviation 0.51
Values 1.2 0.49 1.7 0.91
[323]
ref_hepatocyte KL
Mean 0.258
Standard deviation 0.29
Values 0 0 0.4 0.2 0.69
[324]
HepG2 KL
Mean 0.00858
Standard deviation 0.012
Values 0 0.017
[325]
HepG2.C3A KL
Mean 0
Standard deviation 0
Values 0 0
[326]
HuH.7 KL
Mean 0
Standard deviation 0
Values 0 0 0
[327]
SNU475 KL
Mean 0.181
Standard deviation 0.026
Values 0.2 0.16
[328]
THLE KL
Mean 0.00532
Standard deviation 0.0075
Values 0 0.011
[329]
liver KL
Mean 0.436
Standard deviation 0.32
Values 0.38 0.31 0.15 0.9
[330]
ref_hepatocyte FGF5
Mean 0.241
Standard deviation 0.27
Values 0.042 0.036 0.09 0.64 0.4
[331]
HepG2 FGF5
Mean 0.268
Standard deviation 0.022
Values 0.25 0.28
[332]
HepG2.C3A FGF5
Mean 0.596
Standard deviation 0.024
Values 0.61 0.58
[333]
HuH.7 FGF5
Mean 0.543
Standard deviation 0.15
Values 0.62 0.65 0.37
[334]
SNU475 FGF5
Mean 1.24
Standard deviation 0.35
Values 0.99 1.5
[335]
THLE FGF5
Mean 1.11
Standard deviation 0.17
Values 0.99 1.2
[336]
liver FGF5
Mean 3.01
Standard deviation 1.5
Values 2.3 4.5 1.2 4.1
[337]
ref_hepatocyte EREG
Mean 0.24
Standard deviation 0.13
Values 0.3 0.18 0.15 0.13 0.45
[338]
HepG2 EREG
Mean 1.79
Standard deviation 1.2
Values 2.6 0.95
[339]
HepG2.C3A EREG
Mean 1.51
Standard deviation 1
Values 0.81 2.2
[340]
HuH.7 EREG
Mean 0.068
Standard deviation 0.032
Values 0.033 0.096 0.075
[341]
SNU475 EREG
Mean 0.149
Standard deviation 0.12
Values 0.065 0.23
[342]
THLE EREG
Mean 6.34
Standard deviation 2.2
Values 7.9 4.8
[343]
liver EREG
Mean 0.123
Standard deviation 0.11
Values 0 0.13 0.26 0.11
[344]
ref_hepatocyte FGF1
Mean 0.126
Standard deviation 0.27
Values 0 0.6 0 0 0.024
[345]
HepG2 FGF1
Mean 0.0408
Standard deviation 0.04
Values 0.069 0.013
[346]
HepG2.C3A FGF1
Mean 0.0628
Standard deviation 0.048
Values 0.029 0.097
[347]
HuH.7 FGF1
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[348]
SNU475 FGF1
Mean 0.346
Standard deviation 0.077
Values 0.29 0.4
[349]
THLE FGF1
Mean 1.16
Standard deviation 0.44
Values 0.85 1.5
[350]
liver FGF1
Mean 0.184
Standard deviation 0.042
Values 0.14 0.21 0.15 0.23
[351]
ref_hepatocyte FGF19
Mean 0.122
Standard deviation 0.27
Values 0 0 0.61 0 0
[352]
HepG2 FGF19
Mean 0.0644
Standard deviation 0.0062
Values 0.069 0.06
[353]
HepG2.C3A FGF19
Mean 0.128
Standard deviation 0.0016
Values 0.13 0.13
[354]
HuH.7 FGF19
Mean 13.1
Standard deviation 3.4
Values 11 17 12
[355]
SNU475 FGF19
Mean 0.397
Standard deviation 0.15
Values 0.51 0.29
[356]
THLE FGF19
Mean 0.0402
Standard deviation 0.027
Values 0.059 0.021
[357]
liver FGF19
Mean 0
Standard deviation 0
Values 0 0 0 0
[358]
ref_hepatocyte KITLG
Mean 0.0988
Standard deviation 0.16
Values 0.024 0.39 0 0.052 0.033
[359]
HepG2 KITLG
Mean 9.5
Standard deviation 3.6
Values 6.9 12
[360]
HepG2.C3A KITLG
Mean 0.616
Standard deviation 0.27
Values 0.43 0.8
[361]
HuH.7 KITLG
Mean 31.3
Standard deviation 8.5
Values 41 24 29
[362]
SNU475 KITLG
Mean 19.3
Standard deviation 0.86
Values 20 19
[363]
THLE KITLG
Mean 6.16
Standard deviation 2
Values 7.6 4.7
[364]
liver KITLG
Mean 1.15
Standard deviation 0.074
Values 1.2 1.2 1.1 1.1
[365]
ref_hepatocyte CD28
Mean 0.0933
Standard deviation 0.1
Values 0.14 0 0 0.086 0.24
[366]
HepG2 CD28
Mean 0.0129
Standard deviation 0.018
Values 0 0.026
[367]
HepG2.C3A CD28
Mean 0.0209
Standard deviation 0.016
Values 0.0097 0.032
[368]
HuH.7 CD28
Mean 0.0205
Standard deviation 0.023
Values 0.0082 0.0064 0.047
[369]
SNU475 CD28
Mean 0.0338
Standard deviation 0.0047
Values 0.037 0.03
[370]
THLE CD28
Mean 0.0364
Standard deviation 0.0012
Values 0.035 0.037
[371]
liver CD28
Mean 0.288
Standard deviation 0.19
Values 0.094 0.27 0.23 0.56
[372]
ref_hepatocyte KIT
Mean 0.0798
Standard deviation 0.075
Values 0 0 0.15 0.1 0.15
[373]
HepG2 KIT
Mean 0.0222
Standard deviation 0.025
Values 0.04 0.0043
[374]
HepG2.C3A KIT
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[375]
HuH.7 KIT
Mean 0
Standard deviation 0
Values 0 0 0
[376]
SNU475 KIT
Mean 0.83
Standard deviation 0.64
Values 1.3 0.38
[377]
THLE KIT
Mean 0.0201
Standard deviation 0.013
Values 0.03 0.011
[378]
liver KIT
Mean 1.41
Standard deviation 1.3
Values 0.21 3 1.9 0.54
[379]
ref_hepatocyte CD19
Mean 0.0626
Standard deviation 0.11
Values 0 0 0 0.069 0.24
[380]
HepG2 CD19
Mean 0.596
Standard deviation 0.49
Values 0.94 0.25
[381]
HepG2.C3A CD19
Mean 1.72
Standard deviation 0.22
Values 1.9 1.6
[382]
HuH.7 CD19
Mean 0.0579
Standard deviation 0.035
Values 0.049 0.096 0.028
[383]
SNU475 CD19
Mean 0.0416
Standard deviation 0.013
Values 0.032 0.051
[384]
THLE CD19
Mean 0
Standard deviation 0
Values 0 0
[385]
liver CD19
Mean 0.186
Standard deviation 0.21
Values 0.45 0 0.26 0.04
[386]
ref_hepatocyte CD80
Mean 0.0435
Standard deviation 0.06
Values 0 0 0 0.1 0.11
[387]
HepG2 CD80
Mean 0
Standard deviation 0
Values 0 0
[388]
HepG2.C3A CD80
Mean 0
Standard deviation 0
Values 0 0
[389]
HuH.7 CD80
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[390]
SNU475 CD80
Mean 0.0359
Standard deviation 0.015
Values 0.046 0.025
[391]
THLE CD80
Mean 0.0192
Standard deviation 0.01
Values 0.012 0.027
[392]
liver CD80
Mean 0.381
Standard deviation 0.28
Values 0.12 0.64 0.15 0.61
[393]
ref_hepatocyte FLT3
Mean 0.0374
Standard deviation 0.084
Values 0 0 0 0 0.19
[394]
HepG2 FLT3
Mean 0
Standard deviation 0
Values 0 0
[395]
HepG2.C3A FLT3
Mean 0
Standard deviation 0
Values 0 0
[396]
HuH.7 FLT3
Mean 0.00625
Standard deviation 0.011
Values 0 0 0.019
[397]
SNU475 FLT3
Mean 0.00992
Standard deviation 0.0075
Values 0.0046 0.015
[398]
THLE FLT3
Mean 0
Standard deviation 0
Values 0 0
[399]
liver FLT3
Mean 0.402
Standard deviation 0.15
Values 0.21 0.44 0.39 0.57
[400]
ref_hepatocyte ESR2
Mean 0.0345
Standard deviation 0.077
Values 0 0 0 0.17 0
[401]
HepG2 ESR2
Mean 0.0515
Standard deviation 0.024
Values 0.034 0.069
[402]
HepG2.C3A ESR2
Mean 0.0593
Standard deviation 0.054
Values 0.097 0.021
[403]
HuH.7 ESR2
Mean 0.0579
Standard deviation 0.035
Values 0.049 0.096 0.028
[404]
SNU475 ESR2
Mean 0.0984
Standard deviation 0.047
Values 0.065 0.13
[405]
THLE ESR2
Mean 0.118
Standard deviation 0.00092
Values 0.12 0.12
[406]
liver ESR2
Mean 0.283
Standard deviation 0.18
Values 0.24 0.2 0.15 0.54
[407]
ref_hepatocyte TRAT1
Mean 0.0293
Standard deviation 0.065
Values 0 0 0 0 0.15
[408]
HepG2 TRAT1
Mean 0
Standard deviation 0
Values 0 0
[409]
HepG2.C3A TRAT1
Mean 0
Standard deviation 0
Values 0 0
[410]
HuH.7 TRAT1
Mean 0
Standard deviation 0
Values 0 0 0
[411]
SNU475 TRAT1
Mean 0
Standard deviation 0
Values 0 0
[412]
THLE TRAT1
Mean 0
Standard deviation 0
Values 0 0
[413]
liver TRAT1
Mean 0.287
Standard deviation 0.051
Values 0.33 0.26 0.23 0.33
[414]
ref_hepatocyte ICOS
Mean 0.0282
Standard deviation 0.041
Values 0 0 0 0.052 0.089
[415]
HepG2 ICOS
Mean 0
Standard deviation 0
Values 0 0
[416]
HepG2.C3A ICOS
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[417]
HuH.7 ICOS
Mean 0
Standard deviation 0
Values 0 0 0
[418]
SNU475 ICOS
Mean 0
Standard deviation 0
Values 0 0
[419]
THLE ICOS
Mean 0
Standard deviation 0
Values 0 0
[420]
liver ICOS
Mean 0.0272
Standard deviation 0.033
Values 0 0.043 0 0.066
[421]
ref_hepatocyte HGF
Mean 0.0217
Standard deviation 0.03
Values 0 0 0 0.052 0.057
[422]
HepG2 HGF
Mean 0
Standard deviation 0
Values 0 0
[423]
HepG2.C3A HGF
Mean 0
Standard deviation 0
Values 0 0
[424]
HuH.7 HGF
Mean 0.0131
Standard deviation 0.017
Values 0.033 0.0064 0
[425]
SNU475 HGF
Mean 0.963
Standard deviation 0.42
Values 1.3 0.67
[426]
THLE HGF
Mean 0.138
Standard deviation 0.061
Values 0.095 0.18
[427]
liver HGF
Mean 14.7
Standard deviation 7.2
Values 9.2 24 9.5 16
[428]
ref_hepatocyte FGF8
Mean 0.0195
Standard deviation 0.044
Values 0 0 0 0 0.098
[429]
HepG2 FGF8
Mean 0.00429
Standard deviation 0.0061
Values 0 0.0086
[430]
HepG2.C3A FGF8
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[431]
HuH.7 FGF8
Mean 0.105
Standard deviation 0.073
Values 0.19 0.051 0.075
[432]
SNU475 FGF8
Mean 0.00949
Standard deviation 0.0063
Values 0.014 0.0051
[433]
THLE FGF8
Mean 0
Standard deviation 0
Values 0 0
[434]
liver FGF8
Mean 0.18
Standard deviation 0.14
Values 0.047 0.34 0.077 0.25
[435]
ref_hepatocyte FGF18
Mean 0.0138
Standard deviation 0.031
Values 0 0 0 0.069 0
[436]
HepG2 FGF18
Mean 0.105
Standard deviation 0.039
Values 0.13 0.077
[437]
HepG2.C3A FGF18
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[438]
HuH.7 FGF18
Mean 0.0232
Standard deviation 0.02
Values 0 0.032 0.037
[439]
SNU475 FGF18
Mean 0.0388
Standard deviation 0.0024
Values 0.037 0.041
[440]
THLE FGF18
Mean 0.0657
Standard deviation 0.033
Values 0.089 0.043
[441]
liver FGF18
Mean 0.0294
Standard deviation 0.0072
Values 0.024 0.029 0.026 0.04
[442]
ref_hepatocyte FGF9
Mean 0.0065
Standard deviation 0.015
Values 0 0 0 0 0.033
[443]
HepG2 FGF9
Mean 0.0687
Standard deviation 9.1e-05
Values 0.069 0.069
[444]
HepG2.C3A FGF9
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[445]
HuH.7 FGF9
Mean 0
Standard deviation 0
Values 0 0 0
[446]
SNU475 FGF9
Mean 0.0822
Standard deviation 0.08
Values 0.14 0.025
[447]
THLE FGF9
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[448]
liver FGF9
Mean 0.00993
Standard deviation 0.02
Values 0 0 0 0.04
[449]
ref_hepatocyte EGF
Mean 0.00415
Standard deviation 0.0093
Values 0 0.021 0 0 0
[450]
HepG2 EGF
Mean 0.0358
Standard deviation 0.014
Values 0.046 0.026
[451]
HepG2.C3A EGF
Mean 0.11
Standard deviation 0.087
Values 0.049 0.17
[452]
HuH.7 EGF
Mean 1.29
Standard deviation 0.44
Values 0.97 1.8 1.1
[453]
SNU475 EGF
Mean 3.97
Standard deviation 0.5
Values 4.3 3.6
[454]
THLE EGF
Mean 0.743
Standard deviation 0.02
Values 0.76 0.73
[455]
liver EGF
Mean 0.0176
Standard deviation 0.027
Values 0 0.057 0 0.013
[456]
ref_hepatocyte FGF17
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[457]
HepG2 FGF17
Mean 0.398
Standard deviation 0.15
Values 0.5 0.29
[458]
HepG2.C3A FGF17
Mean 1.23
Standard deviation 1.1
Values 2 0.46
[459]
HuH.7 FGF17
Mean 0.183
Standard deviation 0.2
Values 0.074 0.41 0.066
[460]
SNU475 FGF17
Mean 0.00232
Standard deviation 0.0033
Values 0.0046 0
[461]
THLE FGF17
Mean 0.0228
Standard deviation 0.0096
Values 0.03 0.016
[462]
liver FGF17
Mean 0.00588
Standard deviation 0.012
Values 0.024 0 0 0
[463]
ref_hepatocyte FGF22
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[464]
HepG2 FGF22
Mean 0.01
Standard deviation 0.002
Values 0.011 0.0086
[465]
HepG2.C3A FGF22
Mean 0
Standard deviation 0
Values 0 0
[466]
HuH.7 FGF22
Mean 0.00625
Standard deviation 0.011
Values 0 0 0.019
[467]
SNU475 FGF22
Mean 0.00464
Standard deviation 0.0066
Values 0.0093 0
[468]
THLE FGF22
Mean 0
Standard deviation 0
Values 0 0
[469]
liver FGF22
Mean 0
Standard deviation 0
Values 0 0 0 0
[470]
ref_hepatocyte FGF10
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[471]
HepG2 FGF10
Mean 0
Standard deviation 0
Values 0 0
[472]
HepG2.C3A FGF10
Mean 0
Standard deviation 0
Values 0 0
[473]
HuH.7 FGF10
Mean 0
Standard deviation 0
Values 0 0 0
[474]
SNU475 FGF10
Mean 0
Standard deviation 0
Values 0 0
[475]
THLE FGF10
Mean 0
Standard deviation 0
Values 0 0
[476]
liver FGF10
Mean 0.0234
Standard deviation 0.038
Values 0 0.014 0 0.079
[477]
ref_hepatocyte FGF20
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[478]
HepG2 FGF20
Mean 0.0115
Standard deviation 0.016
Values 0.023 0
[479]
HepG2.C3A FGF20
Mean 0
Standard deviation 0
Values 0 0
[480]
HuH.7 FGF20
Mean 0
Standard deviation 0
Values 0 0 0
[481]
SNU475 FGF20
Mean 0.00485
Standard deviation 0.0003
Values 0.0046 0.0051
[482]
THLE FGF20
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[483]
liver FGF20
Mean 0.0118
Standard deviation 0.024
Values 0.047 0 0 0
[484]
ref_hepatocyte FGF23
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[485]
HepG2 FGF23
Mean 0
Standard deviation 0
Values 0 0
[486]
HepG2.C3A FGF23
Mean 0
Standard deviation 0
Values 0 0
[487]
HuH.7 FGF23
Mean 0.00312
Standard deviation 0.0054
Values 0 0 0.0094
[488]
SNU475 FGF23
Mean 0
Standard deviation 0
Values 0 0
[489]
THLE FGF23
Mean 0
Standard deviation 0
Values 0 0
[490]
liver FGF23
Mean 0.68
Standard deviation 0.31
Values 0.59 0.67 1.1 0.36
[491]
ref_hepatocyte FGF3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[492]
HepG2 FGF3
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[493]
HepG2.C3A FGF3
Mean 0
Standard deviation 0
Values 0 0
[494]
HuH.7 FGF3
Mean 0.00487
Standard deviation 0.0043
Values 0.0082 0.0064 0
[495]
SNU475 FGF3
Mean 0.00717
Standard deviation 0.003
Values 0.0093 0.0051
[496]
THLE FGF3
Mean 0
Standard deviation 0
Values 0 0
[497]
liver FGF3
Mean 0
Standard deviation 0
Values 0 0 0 0
[498]
ref_hepatocyte FGF16
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[499]
HepG2 FGF16
Mean 0
Standard deviation 0
Values 0 0
[500]
HepG2.C3A FGF16
Mean 0
Standard deviation 0
Values 0 0
[501]
HuH.7 FGF16
Mean 0
Standard deviation 0
Values 0 0 0
[502]
SNU475 FGF16
Mean 0
Standard deviation 0
Values 0 0
[503]
THLE FGF16
Mean 0
Standard deviation 0
Values 0 0
[504]
liver FGF16
Mean 0.0118
Standard deviation 0.024
Values 0.047 0 0 0
[505]
ref_hepatocyte ERBB4
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[506]
HepG2 ERBB4
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[507]
HepG2.C3A ERBB4
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[508]
HuH.7 ERBB4
Mean 0.136
Standard deviation 0.15
Values 0.098 0.3 0.0094
[509]
SNU475 ERBB4
Mean 0.0217
Standard deviation 0.0021
Values 0.023 0.02
[510]
THLE ERBB4
Mean 0.0662
Standard deviation 0.027
Values 0.047 0.085
[511]
liver ERBB4
Mean 0.308
Standard deviation 0.33
Values 0.14 0.29 0.026 0.78
[512]
ref_hepatocyte FGF4
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[513]
HepG2 FGF4
Mean 0
Standard deviation 0
Values 0 0
[514]
HepG2.C3A FGF4
Mean 0
Standard deviation 0
Values 0 0
[515]
HuH.7 FGF4
Mean 0
Standard deviation 0
Values 0 0 0
[516]
SNU475 FGF4
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[517]
THLE FGF4
Mean 0
Standard deviation 0
Values 0 0
[518]
liver FGF4
Mean 0
Standard deviation 0
Values 0 0 0 0
[519]
ref_hepatocyte NRG3
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[520]
HepG2 NRG3
Mean 0
Standard deviation 0
Values 0 0
[521]
HepG2.C3A NRG3
Mean 0
Standard deviation 0
Values 0 0
[522]
HuH.7 NRG3
Mean 0.376
Standard deviation 0.32
Values 0.18 0.75 0.2
[523]
SNU475 NRG3
Mean 0
Standard deviation 0
Values 0 0
[524]
THLE NRG3
Mean 0
Standard deviation 0
Values 0 0
[525]
liver NRG3
Mean 0.222
Standard deviation 0.073
Values 0.28 0.2 0.13 0.28
[526]
ref_hepatocyte NRG2
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[527]
HepG2 NRG2
Mean 0.0236
Standard deviation 0.015
Values 0.034 0.013
[528]
HepG2.C3A NRG2
Mean 0
Standard deviation 0
Values 0 0
[529]
HuH.7 NRG2
Mean 0
Standard deviation 0
Values 0 0 0
[530]
SNU475 NRG2
Mean 0.181
Standard deviation 0.12
Values 0.093 0.27
[531]
THLE NRG2
Mean 0.79
Standard deviation 0.23
Values 0.63 0.95
[532]
liver NRG2
Mean 0.0321
Standard deviation 0.024
Values 0.047 0.029 0 0.053
[533]
ref_hepatocyte FGF6
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[534]
HepG2 FGF6
Mean 0.00287
Standard deviation 0.0041
Values 0.0057 0
[535]
HepG2.C3A FGF6
Mean 0
Standard deviation 0
Values 0 0
[536]
HuH.7 FGF6
Mean 0
Standard deviation 0
Values 0 0 0
[537]
SNU475 FGF6
Mean 0
Standard deviation 0
Values 0 0
[538]
THLE FGF6
Mean 0
Standard deviation 0
Values 0 0
[539]
liver FGF6
Mean 0.00357
Standard deviation 0.0071
Values 0 0.014 0 0
[540]
ref_hepatocyte EPGN
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[541]
HepG2 EPGN
Mean 0.0544
Standard deviation 0.028
Values 0.074 0.034
[542]
HepG2.C3A EPGN
Mean 0.0501
Standard deviation 0.025
Values 0.068 0.032
[543]
HuH.7 EPGN
Mean 0.127
Standard deviation 0.084
Values 0.082 0.22 0.075
[544]
SNU475 EPGN
Mean 0.503
Standard deviation 0.27
Values 0.31 0.69
[545]
THLE EPGN
Mean 4.76
Standard deviation 1.2
Values 5.6 3.9
[546]
liver EPGN
Mean 0.161
Standard deviation 0.11
Values 0.12 0.17 0.051 0.3