REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | GNAS | Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas | 0.34[1] | 0.44[2] | 0.01[3] | 0.27[4] | -0.31[5] | -0.97[6] | |
2 | GNG5 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 | -1.29[7] | -1.05[8] | -2.00[9] | -2.39[10] | -2.46[11] | -1.22[12] | |
3 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | [13] | 0.93[14] | 1.00[15] | 0.44[16] | 0.71[17] | 0.69[18] | -0.87[19] |
4 | GNB2 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 | [20] | -0.69[21] | -0.88[22] | -0.63[23] | -0.94[24] | -0.70[25] | -1.24[26] |
5 | GNG10 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 | -4.79[27] | -4.44[28] | -4.83[29] | -4.39[30] | -3.39[31] | -3.98[32] | |
6 | GNG12 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 | -4.84[33] | -7.71[34] | 0.15[35] | 1.30[36] | 1.58[37] | 0.85[38] | |
7 | ADM | ADM | [39] | -0.17[40] | -0.80[41] | -1.52[42] | 0.08[43] | -0.23[44] | -0.45[45] |
8 | CD55 | Complement decay-accelerating factor | [46] | -1.37[47] | -1.72[48] | -1.31[49] | -1.25[50] | 0.43[51] | -0.78[52] |
9 | WNT11 | Protein Wnt-11 | [53] | -1.51[54] | -7.16[55] | -6.22[56] | -7.11[57] | -7.35[58] | -2.72[59] |
10 | RAMP1 | Receptor activity-modifying protein 1 | [60] | -4.64[61] | -9.19[62] | -1.73[63] | -4.04[64] | -3.99[65] | 0.94[66] |
11 | FZD5 | Frizzled-5 | [67] | 0.88[68] | 1.81[69] | 2.72[70] | -1.71[71] | -2.84[72] | 2.95[73] |
12 | CALCA | Calcitonin | [74] | [75] | [76] | -10.55[77] | [78] | -9.54[79] | -0.74[80] |
13 | GNB5 | Guanine nucleotide-binding protein subunit beta-5 | [81] | 0.01[82] | 0.11[83] | 1.04[84] | 0.21[85] | 0.52[86] | 1.25[87] |
14 | SMO | Smoothened homolog | [88] | 1.08[89] | 1.52[90] | 1.59[91] | 0.57[92] | 0.03[93] | 0.61[94] |
15 | FZD4 | Frizzled-4 | [95] | 4.00[96] | 3.00[97] | 1.95[98] | 0.12[99] | -0.37[100] | 3.31[101] |
16 | CRHBP | Corticotropin-releasing factor-binding protein | [102] | [103] | -9.54[104] | [105] | -10.93[106] | -10.84[107] | 4.19[108] |
17 | GNG11 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 | -8.27[109] | -8.20[110] | -7.60[111] | 1.69[112] | 3.19[113] | 2.60[114] | |
18 | ADM2 | ADM2 | [115] | 0.94[116] | 1.22[117] | 2.87[118] | -2.44[119] | -0.49[120] | 0.38[121] |
19 | FZD6 | Frizzled-6 | [122] | 1.70[123] | 2.58[124] | -0.01[125] | 4.16[126] | 3.10[127] | 1.48[128] |
20 | SHH | Sonic hedgehog protein | [129] | 0.29[130] | 0.21[131] | 0.20[132] | -7.76[133] | -7.71[134] | 0.49[135] |
21 | GNG7 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 | 1.47[136] | 1.18[137] | 1.90[138] | -2.81[139] | -2.01[140] | 0.39[141] | |
22 | FZD8 | Frizzled-8 | [142] | -3.21[143] | -8.49[144] | -1.20[145] | -3.54[146] | -2.15[147] | 0.17[148] |
23 | WNT3 | Proto-oncogene Wnt-3 | [149] | -0.47[150] | 0.54[151] | -1.47[152] | -1.14[153] | -2.30[154] | 0.54[155] |
24 | RAMP3 | Receptor activity-modifying protein 3 | [156] | [157] | [158] | [159] | -9.69[160] | [161] | 3.41[162] |
25 | RAMP2 | Receptor activity-modifying protein 2 | [163] | -1.22[164] | -0.93[165] | 1.61[166] | -1.97[167] | -1.83[168] | 1.44[169] |
26 | GNG4 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 | 3.38[170] | 1.21[171] | 4.92[172] | 0.68[173] | -1.25[174] | -2.19[175] | |
27 | UCN | Urocortin | [176] | -2.07[177] | -0.41[178] | -1.26[179] | -2.53[180] | -3.21[181] | -1.66[182] |
28 | GNB4 | Guanine nucleotide-binding protein subunit beta-4 | [183] | -0.46[184] | 0.10[185] | 1.01[186] | 2.11[187] | 5.03[188] | 4.45[189] |
29 | FZD7 | Frizzled-7 | [190] | 2.11[191] | -1.86[192] | 4.06[193] | 3.98[194] | 1.57[195] | 0.39[196] |
30 | GNG2 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | -6.37[197] | -7.18[198] | [199] | 2.54[200] | 2.20[201] | 3.14[202] | |
31 | IAPP | Islet amyloid polypeptide | [203] | -1.97[204] | -1.20[205] | -1.11[206] | -2.48[207] | -2.23[208] | -1.10[209] |
32 | WNT4 | Protein Wnt-4 | [210] | -3.78[211] | -2.85[212] | -4.05[213] | -1.94[214] | -3.08[215] | 0.58[216] |
33 | FZD1 | Frizzled-1 | [217] | 1.46[218] | -0.44[219] | 3.16[220] | 1.84[221] | 3.15[222] | 3.15[223] |
34 | WNT5A | Protein Wnt-5a | [224] | -3.28[225] | -3.21[226] | -2.13[227] | 6.02[228] | 7.77[229] | 1.68[230] |
35 | PTCH1 | Protein patched homolog 1 | [231] | 2.55[232] | 2.85[233] | 4.13[234] | 2.75[235] | 2.27[236] | 3.21[237] |
36 | IHH | Indian hedgehog protein | [238] | 0.97[239] | -0.92[240] | 4.81[241] | -4.87[242] | -5.55[243] | 0.46[244] |
37 | WNT7B | Protein Wnt-7b | [245] | 2.60[246] | 0.85[247] | 0.51[248] | -0.25[249] | -1.01[250] | -0.46[251] |
38 | FZD3 | Frizzled-3 | [252] | 2.84[253] | 3.84[254] | 5.45[255] | 3.22[256] | 2.63[257] | 4.01[258] |
39 | GNGT2 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 | [259] | [260] | [261] | -2.64[262] | -7.13[263] | 0.47[264] | |
40 | WNT9B | Protein Wnt-9b | [265] | -4.14[266] | -4.90[267] | -1.43[268] | [269] | [270] | -4.49[271] |
41 | SCTR | Secretin receptor | [272] | -1.65[273] | 0.96[274] | 2.03[275] | -0.52[276] | -5.07[277] | 1.61[278] |
42 | GNG3 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 | -0.94[279] | 0.95[280] | -1.36[281] | -1.28[282] | -1.41[283] | 0.28[284] | |
43 | FZD2 | Frizzled-2 | [285] | 1.06[286] | -0.49[287] | 2.13[288] | 6.31[289] | 3.95[290] | 0.00[291] |
44 | WNT9A | Protein Wnt-9a | [292] | -0.04[293] | -3.10[294] | -3.97[295] | 0.66[296] | -1.37[297] | -2.26[298] |
45 | CRHR1 | Corticotropin-releasing factor receptor 1 | [299] | [300] | -5.50[301] | -6.16[302] | [303] | [304] | [305] |
46 | GLP2R | Glucagon-like peptide 2 receptor | [306] | -1.64[307] | -3.54[308] | [309] | 2.69[310] | -0.60[311] | 1.62[312] |
47 | FZD9 | Frizzled-9 | [313] | 1.33[314] | 1.58[315] | 1.24[316] | 1.56[317] | -0.56[318] | -0.03[319] |
48 | PTHLH | Parathyroid hormone-related protein | [320] | 1.80[321] | 1.40[322] | -3.25[323] | 3.93[324] | 1.36[325] | [326] |
49 | VIPR1 | Vasoactive intestinal polypeptide receptor 1 | [327] | -0.05[328] | -0.67[329] | -0.54[330] | -2.98[331] | 3.36[332] | 7.04[333] |
50 | WNT2B | Protein Wnt-2b | [334] | -0.72[335] | 0.13[336] | 0.03[337] | 2.02[338] | 1.52[339] | 1.29[340] |
51 | GNB3 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 | [341] | 1.50[342] | 3.82[343] | 3.03[344] | 0.43[345] | 3.33[346] | -1.32[347] |
52 | CALCRL | Calcitonin gene-related peptide type 1 receptor | [348] | -3.09[349] | -2.34[350] | -2.40[351] | 3.93[352] | 3.29[353] | 7.49[354] |
53 | WNT16 | Protein Wnt-16 | [355] | [356] | [357] | [358] | 0.77[359] | -2.92[360] | 0.52[361] |
54 | VIP | VIP peptides | [362] | -1.08[363] | -0.98[364] | [365] | -0.25[366] | -2.11[367] | 2.03[368] |
55 | PTCH2 | Protein patched homolog 2 | [369] | 3.14[370] | 4.52[371] | 0.84[372] | -0.06[373] | 1.30[374] | 2.29[375] |
56 | GIPR | Gastric inhibitory polypeptide receptor | [376] | 1.33[377] | 2.30[378] | 4.09[379] | 1.61[380] | 1.37[381] | 0.61[382] |
57 | WNT10A | Protein Wnt-10a | [383] | 1.16[384] | -2.12[385] | -4.91[386] | 2.97[387] | -2.62[388] | -1.12[389] |
58 | ADCYAP1 | Pituitary adenylate cyclase-activating polypeptide | [390] | [391] | [392] | 1.06[393] | 2.45[394] | 1.62[395] | -0.83[396] |
59 | PTH1R | Parathyroid hormone/parathyroid hormone-related peptide receptor | -0.47[397] | [398] | -0.37[399] | -1.63[400] | 1.25[401] | 8.59[402] | |
60 | CRHR2 | Corticotropin-releasing factor receptor 2 | [403] | -3.22[404] | [405] | 0.00[406] | -2.68[407] | -0.15[408] | 0.44[409] |
61 | WNT2 | Protein Wnt-2 | [410] | [411] | [412] | -2.11[413] | 0.36[414] | -3.39[415] | 6.58[416] |
62 | PTH2R | Parathyroid hormone 2 receptor | [417] | 1.34[418] | 0.26[419] | 10.33[420] | -0.54[421] | 0.46[422] | 2.89[423] |
63 | CYSLTR2 | Cysteinyl leukotriene receptor 2 | [424] | [425] | -1.42[426] | [427] | -2.81[428] | -1.57[429] | 2.81[430] |
64 | ADCYAP1 | Pituitary adenylate cyclase-activating polypeptide type I receptor | [431] | -0.70[432] | [433] | -2.51[434] | 1.77[435] | [436] | 5.85[437] |
65 | VIPR2 | Vasoactive intestinal polypeptide receptor 2 | [438] | -0.42[439] | 1.67[440] | 1.12[441] | 5.23[442] | 1.37[443] | 4.93[444] |
66 | WNT6 | Protein Wnt-6 | [445] | [446] | [447] | [448] | [449] | [450] | [451] |
67 | ADGRE3 | Adhesion G protein-coupled receptor E3 | [452] | [453] | [454] | [455] | [456] | [457] | [458] |
68 | ADGRE2 | Adhesion G protein-coupled receptor E2 | [459] | [460] | [461] | [462] | [463] | [464] | [465] |
69 | CALCB | Calcitonin gene-related peptide 2 | [466] | [467] | [468] | [469] | [470] | [471] | [472] |
70 | ADGRE1 | Adhesion G protein-coupled receptor E1 | [473] | [474] | [475] | [476] | [477] | [478] | [479] |
71 | WNT3A | Protein Wnt-3a | [480] | [481] | [482] | [483] | [484] | [485] | [486] |
72 | GCG | Glucagon | [487] | [488] | [489] | [490] | [491] | [492] | [493] |
73 | GIP | Gastric inhibitory polypeptide | [494] | [495] | [496] | [497] | [498] | [499] | [500] |
74 | PTH | Parathyroid hormone | [501] | [502] | [503] | [504] | [505] | [506] | [507] |
75 | WNT1 | Proto-oncogene Wnt-1 | [508] | [509] | [510] | [511] | [512] | [513] | [514] |
76 | WNT8A | Protein Wnt-8a | [515] | [516] | [517] | [518] | [519] | [520] | [521] |
77 | UCN3 | Urocortin-3 | [522] | [523] | [524] | [525] | [526] | [527] | [528] |
78 | GHRH | Somatoliberin | [529] | [530] | [531] | [532] | [533] | [534] | [535] |
79 | GNG13 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 | [536] | [537] | [538] | [539] | [540] | [541] | |
80 | GHRHR | Growth hormone-releasing hormone receptor | [542] | [543] | [544] | [545] | [546] | [547] | [548] |
81 | DHH | Desert hedgehog protein | [549] | [550] | [551] | [552] | [553] | [554] | [555] |
82 | GNGT1 | Guanine nucleotide-binding protein G(T) subunit gamma-T1 | [556] | [557] | [558] | [559] | [560] | [561] | [562] |
83 | UCN2 | Urocortin-2 | [563] | [564] | [565] | [566] | [567] | [568] | [569] |
84 | GLP1R | Glucagon-like peptide 1 receptor | [570] | [571] | [572] | [573] | [574] | [575] | [576] |
85 | ADGRE5 | [577] | [578] | [579] | [580] | [581] | [582] | [583] | |
86 | SCT | Secretin | [584] | [585] | [586] | [587] | [588] | [589] | [590] |
87 | PTH2 | Tuberoinfundibular peptide of 39 residues | [591] | [592] | [593] | [594] | [595] | [596] | [597] |
88 | WNT8B | Protein Wnt-8b | [598] | [599] | [600] | [601] | [602] | [603] | [604] |
89 | FZD10 | Frizzled-10 | [605] | [606] | [607] | [608] | [609] | [610] | [611] |
90 | WNT10B | Protein Wnt-10b | [612] | [613] | [614] | [615] | [616] | [617] | [618] |
91 | CALCR | Calcitonin receptor | [619] | [620] | [621] | [622] | [623] | [624] | [625] |
92 | GNG8 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 | [626] | [627] | [628] | [629] | [630] | [631] | |
93 | CRH | Corticoliberin | [632] | [633] | [634] | [635] | [636] | [637] | [638] |
94 | WNT7A | Protein Wnt-7a | [639] | [640] | [641] | [642] | [643] | [644] | [645] |