REACTOME_CHREBP_ACTIVATES_METABOLIC_GENE_EXPRESSION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 ACLY ATP-citrate synthase [1] 0.26[2] -0.56[3] 0.03[4] 0.81[5] 0.80[6] -1.93[7]
2 MLXIPL Carbohydrate-responsive element-binding protein [8] -2.78[9] -0.87[10] -3.17[11] -8.21[12] -6.25[13] -0.05[14]
3 FASN Fatty acid synthase [15] 1.48[16] 1.64[17] 1.86[18] 0.49[19] 0.74[20] 0.92[21]
4 MLX Max-like protein X [22] -1.26[23] -0.93[24] -1.81[25] -1.04[26] -1.23[27] -2.11[28]
5 AGPAT1 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha [29] -0.06[30] -0.48[31] -1.47[32] 0.31[33] 0.41[34] -2.29[35]
6 PKLR Pyruvate kinase PKLR [36] -2.79[37] -1.39[38] -3.45[39] -10.42[40] -10.10[41] -0.62[42]
7 ACACB Acetyl-CoA carboxylase 2 [43] -1.79[44] -1.30[45] -1.51[46] -2.01[47] -1.50[48] 2.60[49]
8 ACACA Acetyl-CoA carboxylase 1 [50] 1.53[51] 1.39[52] 1.97[53] 2.33[54] 1.75[55] 1.77[56]
[1]
ref_hepatocyte ACLY
Mean 28.9
Standard deviation 24
Values 64 33 33 9.2 4.3
[2]
HepG2 ACLY
Mean 145
Standard deviation 3.8
Values 1.5e+02 1.4e+02
[3]
HepG2.C3A ACLY
Mean 102
Standard deviation 23
Values 1.2e+02 86
[4]
HuH.7 ACLY
Mean 185
Standard deviation 35
Values 2.2e+02 1.5e+02 1.8e+02
[5]
SNU475 ACLY
Mean 111
Standard deviation 0.23
Values 1.1e+02 1.1e+02
[6]
THLE ACLY
Mean 105
Standard deviation 22
Values 89 1.2e+02
[7]
liver ACLY
Mean 32.1
Standard deviation 9.8
Values 25 32 26 46
[8]
ref_hepatocyte MLXIPL
Mean 24.5
Standard deviation 24
Values 21 0.29 3.4 44 54
[9]
HepG2 MLXIPL
Mean 14.9
Standard deviation 1.1
Values 14 16
[10]
HepG2.C3A MLXIPL
Mean 69.5
Standard deviation 28
Values 89 50
[11]
HuH.7 MLXIPL
Mean 17.1
Standard deviation 3.9
Values 13 18 20
[12]
SNU475 MLXIPL
Mean 0.18
Standard deviation 0.047
Values 0.21 0.15
[13]
THLE MLXIPL
Mean 0.675
Standard deviation 0.52
Values 1 0.31
[14]
liver MLXIPL
Mean 101
Standard deviation 65
Values 1.9e+02 43 99 69
[15]
ref_hepatocyte FASN
Mean 16.9
Standard deviation 11
Values 31 3.5 11 17 22
[16]
HepG2 FASN
Mean 197
Standard deviation 11
Values 1.9e+02 2e+02
[17]
HepG2.C3A FASN
Mean 273
Standard deviation 1.4e+02
Values 3.7e+02 1.7e+02
[18]
HuH.7 FASN
Mean 387
Standard deviation 1.1e+02
Values 5e+02 3.8e+02 2.9e+02
[19]
SNU475 FASN
Mean 51.5
Standard deviation 12
Values 60 43
[20]
THLE FASN
Mean 59
Standard deviation 19
Values 46 72
[21]
liver FASN
Mean 136
Standard deviation 1e+02
Values 92 1.2e+02 54 2.8e+02
[22]
ref_hepatocyte MLX
Mean 16.8
Standard deviation 7.6
Values 5.1 15 23 24 17
[23]
HepG2 MLX
Mean 29.3
Standard deviation 0.64
Values 30 29
[24]
HepG2.C3A MLX
Mean 45.8
Standard deviation 2.6
Values 48 44
[25]
HuH.7 MLX
Mean 30.1
Standard deviation 0.31
Values 30 30 30
[26]
SNU475 MLX
Mean 17.8
Standard deviation 1.9
Values 19 16
[27]
THLE MLX
Mean 15
Standard deviation 2.6
Values 13 17
[28]
liver MLX
Mean 16.5
Standard deviation 5.4
Values 21 12 21 12
[29]
ref_hepatocyte AGPAT1
Mean 15.6
Standard deviation 6.2
Values 22 8.4 12 22 13
[30]
HepG2 AGPAT1
Mean 62.6
Standard deviation 7.5
Values 57 68
[31]
HepG2.C3A AGPAT1
Mean 58.2
Standard deviation 4
Values 61 55
[32]
HuH.7 AGPAT1
Mean 35.5
Standard deviation 8.6
Values 43 26 37
[33]
SNU475 AGPAT1
Mean 42.2
Standard deviation 1.5
Values 41 43
[34]
THLE AGPAT1
Mean 43.4
Standard deviation 3.1
Values 41 46
[35]
liver AGPAT1
Mean 13.6
Standard deviation 11
Values 19 4.6 26 4.7
[36]
ref_hepatocyte PKLR
Mean 7.45
Standard deviation 8
Values 8.4 0.078 0.38 8.7 20
[37]
HepG2 PKLR
Mean 4.51
Standard deviation 1.3
Values 3.6 5.4
[38]
HepG2.C3A PKLR
Mean 14.7
Standard deviation 7.4
Values 20 9.5
[39]
HuH.7 PKLR
Mean 4.29
Standard deviation 1.9
Values 3.3 6.5 3.1
[40]
SNU475 PKLR
Mean 0.0118
Standard deviation 0.0095
Values 0.019 0.0051
[41]
THLE PKLR
Mean 0.0142
Standard deviation 0.005
Values 0.018 0.011
[42]
liver PKLR
Mean 20.6
Standard deviation 18
Values 46 5 9.8 22
[43]
ref_hepatocyte ACACB
Mean 5.46
Standard deviation 5.5
Values 1.7 1.8 1.1 9.6 13
[44]
HepG2 ACACB
Mean 6.6
Standard deviation 0.54
Values 6.2 7
[45]
HepG2.C3A ACACB
Mean 11.5
Standard deviation 0.088
Values 11 12
[46]
HuH.7 ACACB
Mean 12.1
Standard deviation 1.9
Values 13 13 9.8
[47]
SNU475 ACACB
Mean 2.94
Standard deviation 0.034
Values 3 2.9
[48]
THLE ACACB
Mean 4.04
Standard deviation 0.24
Values 4.2 3.9
[49]
liver ACACB
Mean 141
Standard deviation 89
Values 90 1.6e+02 59 2.6e+02
[50]
ref_hepatocyte ACACA
Mean 3.02
Standard deviation 0.95
Values 4.3 3.2 1.7 3.2 2.7
[51]
HepG2 ACACA
Mean 36.5
Standard deviation 4.8
Values 33 40
[52]
HepG2.C3A ACACA
Mean 41.2
Standard deviation 13
Values 50 32
[53]
HuH.7 ACACA
Mean 74.7
Standard deviation 16
Values 89 78 57
[54]
SNU475 ACACA
Mean 33.2
Standard deviation 14
Values 43 23
[55]
THLE ACACA
Mean 21.2
Standard deviation 5
Values 18 25
[56]
liver ACACA
Mean 44
Standard deviation 21
Values 21 70 35 50