REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CHPF Chondroitin sulfate synthase 2 [1] 0.00[2] 0.51[3] -0.49[4] -0.57[5] -1.25[6] -0.88[7]
2 CHST13 Carbohydrate sulfotransferase 13 [8] -1.65[9] -1.05[10] 0.33[11] -7.09[12] -10.36[13] -1.83[14]
3 CSGALNACT2 Chondroitin sulfate N-acetylgalactosaminyltransferase 2 [15] -1.99[16] -2.37[17] -1.12[18] -0.16[19] -0.69[20] -1.32[21]
4 CHPF2 Chondroitin sulfate glucuronyltransferase [22] -0.05[23] -0.70[24] 0.71[25] 0.70[26] -0.17[27] -0.66[28]
5 CHST7 Carbohydrate sulfotransferase 7 [29] -1.79[30] -2.40[31] -2.78[32] -1.62[33] -3.73[34] -1.63[35]
6 CHST9 Carbohydrate sulfotransferase 9 [36] -1.66[37] -1.52[38] -0.16[39] -6.99[40] -9.95[41] -2.48[42]
7 CHST12 Carbohydrate sulfotransferase 12 [43] -0.48[44] -0.71[45] 0.48[46] -0.06[47] -0.77[48] -0.57[49]
8 CHSY1 Chondroitin sulfate synthase 1 [50] 1.02[51] 0.05[52] 0.41[53] 2.03[54] 1.29[55] -0.52[56]
9 CHST3 Carbohydrate sulfotransferase 3 [57] 2.58[58] 1.92[59] 0.84[60] 2.16[61] 1.70[62] -0.26[63]
10 DCN Decorin [64] -8.12[65] -10.12[66] -5.65[67] 0.71[68] 3.82[69] 4.03[70]
11 CHST15 Carbohydrate sulfotransferase 15 [71] 3.05[72] 3.03[73] 0.68[74] 2.92[75] 1.44[76] 1.97[77]
12 BGN Biglycan [78] 0.18[79] -5.32[80] -5.99[81] 0.95[82] -2.63[83] 3.68[84]
13 VCAN Versican core protein [85] 2.96[86] -2.47[87] 3.24[88] 0.66[89] 3.90[90] 2.16[91]
14 CHSY3 Chondroitin sulfate synthase 3 [92] -3.04[93] -5.86[94] -0.78[95] -4.63[96] -1.97[97] 1.13[98]
15 CSGALNACT1 Chondroitin sulfate N-acetylgalactosaminyltransferase 1 [99] 0.09[100] 1.74[101] 0.53[102] 1.03[103] 3.96[104] 1.15[105]
16 CSPG5 Chondroitin sulfate proteoglycan 5 [106] -3.00[107] -5.99[108] 1.47[109] 0.33[110] -2.85[111] -3.89[112]
17 CHST11 Carbohydrate sulfotransferase 11 [113] -1.18[114] -6.20[115] 2.00[116] 3.33[117] 4.55[118] 2.35[119]
18 NCAN Neurocan core protein [120] -0.08[121] -3.14[122] 0.79[123] -4.39[124] -2.58[125] -2.50[126]
19 CSPG4 Chondroitin sulfate proteoglycan 4 [127] 1.75[128] 0.50[129] 3.89[130] 6.33[131] 5.94[132] 4.13[133]
20 BCAN Brevican core protein [134] 6.42[135] 6.34[136] 6.17[137] 6.53[138] 3.42[139] 1.04[140]
[1]
ref_hepatocyte CHPF
Mean 17.9
Standard deviation 12
Values 10 4.1 17 37 21
[2]
HepG2 CHPF
Mean 136
Standard deviation 9.6
Values 1.4e+02 1.3e+02
[3]
HepG2.C3A CHPF
Mean 208
Standard deviation 87
Values 2.7e+02 1.5e+02
[4]
HuH.7 CHPF
Mean 33
Standard deviation 2.5
Values 34 30 34
[5]
SNU475 CHPF
Mean 39.1
Standard deviation 4.9
Values 43 36
[6]
THLE CHPF
Mean 57.2
Standard deviation 3.5
Values 55 60
[7]
liver CHPF
Mean 43.6
Standard deviation 9
Values 38 44 56 36
[8]
ref_hepatocyte CHST13
Mean 7.95
Standard deviation 5.7
Values 9.3 2.6 1.3 13 14
[9]
HepG2 CHST13
Mean 19.3
Standard deviation 2.6
Values 21 17
[10]
HepG2.C3A CHST13
Mean 31.3
Standard deviation 18
Values 44 19
[11]
HuH.7 CHST13
Mean 25.9
Standard deviation 3.8
Values 23 25 30
[12]
SNU475 CHST13
Mean 0.19
Standard deviation 0.046
Values 0.16 0.22
[13]
THLE CHST13
Mean 0.0458
Standard deviation 0.027
Values 0.065 0.027
[14]
liver CHST13
Mean 10.1
Standard deviation 5.4
Values 18 5.7 8.3 8.3
[15]
ref_hepatocyte CSGALNACT2
Mean 5.09
Standard deviation 4.7
Values 1.7 7.5 12 2.1 1.8
[16]
HepG2 CSGALNACT2
Mean 9.77
Standard deviation 4.4
Values 13 6.7
[17]
HepG2.C3A CSGALNACT2
Mean 8.03
Standard deviation 0.49
Values 8.4 7.7
[18]
HuH.7 CSGALNACT2
Mean 6.07
Standard deviation 1
Values 5.6 7.2 5.4
[19]
SNU475 CSGALNACT2
Mean 14.9
Standard deviation 1
Values 16 14
[20]
THLE CSGALNACT2
Mean 24
Standard deviation 0.53
Values 24 24
[21]
liver CSGALNACT2
Mean 9.16
Standard deviation 1.5
Values 7.5 11 10 8.5
[22]
ref_hepatocyte CHPF2
Mean 4.41
Standard deviation 2.4
Values 2.2 3.2 7.6 6.1 2.9
[23]
HepG2 CHPF2
Mean 32.3
Standard deviation 5
Values 36 29
[24]
HepG2.C3A CHPF2
Mean 22.1
Standard deviation 10
Values 29 15
[25]
HuH.7 CHPF2
Mean 18.7
Standard deviation 1.4
Values 18 20 18
[26]
SNU475 CHPF2
Mean 23.3
Standard deviation 10
Values 30 16
[27]
THLE CHPF2
Mean 29.7
Standard deviation 7.3
Values 25 35
[28]
liver CHPF2
Mean 12.6
Standard deviation 5.2
Values 6.9 18 9.5 16
[29]
ref_hepatocyte CHST7
Mean 2.54
Standard deviation 1.6
Values 0.66 1.8 2.9 2.3 5
[30]
HepG2 CHST7
Mean 5.6
Standard deviation 1.8
Values 6.9 4.3
[31]
HepG2.C3A CHST7
Mean 3.91
Standard deviation 0.81
Values 4.5 3.3
[32]
HuH.7 CHST7
Mean 0.957
Standard deviation 0.28
Values 0.64 1.1 1.1
[33]
SNU475 CHST7
Mean 2.69
Standard deviation 0.31
Values 2.5 2.9
[34]
THLE CHST7
Mean 1.45
Standard deviation 0.089
Values 1.5 1.4
[35]
liver CHST7
Mean 3.7
Standard deviation 1.7
Values 3.1 3.3 2.3 6.2
[36]
ref_hepatocyte CHST9
Mean 2.31
Standard deviation 2.1
Values 2.7 5.6 2.1 0.95 0.25
[37]
HepG2 CHST9
Mean 5.56
Standard deviation 4.2
Values 2.6 8.5
[38]
HepG2.C3A CHST9
Mean 6.54
Standard deviation 3.4
Values 4.1 9
[39]
HuH.7 CHST9
Mean 5.38
Standard deviation 0.62
Values 5.9 5.6 4.7
[40]
SNU475 CHST9
Mean 0.059
Standard deviation 0.048
Values 0.093 0.025
[41]
THLE CHST9
Mean 0.0177
Standard deviation 0.025
Values 0.035 0
[42]
liver CHST9
Mean 1.86
Standard deviation 0.75
Values 1.3 2 1.3 2.9
[43]
ref_hepatocyte CHST12
Mean 1.46
Standard deviation 1.1
Values 3.3 0.45 0.77 1.5 1.3
[44]
HepG2 CHST12
Mean 7.93
Standard deviation 0.32
Values 7.7 8.2
[45]
HepG2.C3A CHST12
Mean 7.23
Standard deviation 1.8
Values 8.5 5.9
[46]
HuH.7 CHST12
Mean 5.26
Standard deviation 0.62
Values 5.6 4.6 5.6
[47]
SNU475 CHST12
Mean 4.55
Standard deviation 0.42
Values 4.8 4.2
[48]
THLE CHST12
Mean 6.5
Standard deviation 1.1
Values 5.7 7.3
[49]
liver CHST12
Mean 4.42
Standard deviation 1.8
Values 4.1 3.4 7.1 3.1
[50]
ref_hepatocyte CHSY1
Mean 1.34
Standard deviation 0.68
Values 2.5 1.2 0.96 1.2 0.8
[51]
HepG2 CHSY1
Mean 20.7
Standard deviation 0.42
Values 20 21
[52]
HepG2.C3A CHSY1
Mean 11.3
Standard deviation 0.17
Values 11 11
[53]
HuH.7 CHSY1
Mean 4.62
Standard deviation 0.53
Values 4.8 4 5.1
[54]
SNU475 CHSY1
Mean 17.8
Standard deviation 2.3
Values 16 19
[55]
THLE CHSY1
Mean 24.8
Standard deviation 1.7
Values 24 26
[56]
liver CHSY1
Mean 4.21
Standard deviation 2.2
Values 2.4 6.1 2.3 6.1
[57]
ref_hepatocyte CHST3
Mean 0.889
Standard deviation 1.5
Values 3.6 0.7 0.13 0 0.0081
[58]
HepG2 CHST3
Mean 40.5
Standard deviation 1.1
Values 41 40
[59]
HepG2.C3A CHST3
Mean 27.4
Standard deviation 0.82
Values 27 28
[60]
HuH.7 CHST3
Mean 4.14
Standard deviation 1.1
Values 4.1 5.3 3
[61]
SNU475 CHST3
Mean 12.9
Standard deviation 1.1
Values 12 14
[62]
THLE CHST3
Mean 21.9
Standard deviation 4.4
Values 19 25
[63]
liver CHST3
Mean 3.35
Standard deviation 2.5
Values 0.99 4.9 1.5 6.1
[64]
ref_hepatocyte DCN
Mean 0.734
Standard deviation 1.2
Values 0 0 0.17 0.72 2.8
[65]
HepG2 DCN
Mean 0.02
Standard deviation 0.0041
Values 0.023 0.017
[66]
HepG2.C3A DCN
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[67]
HuH.7 DCN
Mean 0.038
Standard deviation 0.019
Values 0.057 0.019 0.037
[68]
SNU475 DCN
Mean 3.92
Standard deviation 0.29
Values 3.7 4.1
[69]
THLE DCN
Mean 78.6
Standard deviation 48
Values 1.1e+02 44
[70]
liver DCN
Mean 54.1
Standard deviation 15
Values 60 51 70 35
[71]
ref_hepatocyte CHST15
Mean 0.698
Standard deviation 0.31
Values 0.51 0.61 0.6 0.51 1.3
[72]
HepG2 CHST15
Mean 44.1
Standard deviation 20
Values 58 30
[73]
HepG2.C3A CHST15
Mean 46.5
Standard deviation 12
Values 55 38
[74]
HuH.7 CHST15
Mean 2.9
Standard deviation 0.6
Values 3.6 2.6 2.5
[75]
SNU475 CHST15
Mean 17.2
Standard deviation 0.7
Values 18 17
[76]
THLE CHST15
Mean 14.3
Standard deviation 0.97
Values 15 14
[77]
liver CHST15
Mean 12.3
Standard deviation 4.9
Values 5.8 17 11 15
[78]
ref_hepatocyte BGN
Mean 0.625
Standard deviation 0.62
Values 0.052 0 0.61 1.4 1
[79]
HepG2 BGN
Mean 5.39
Standard deviation 1.6
Values 6.5 4.3
[80]
HepG2.C3A BGN
Mean 0.127
Standard deviation 0.013
Values 0.14 0.12
[81]
HuH.7 BGN
Mean 0.0256
Standard deviation 0.029
Values 0.057 0.019 0
[82]
SNU475 BGN
Mean 3.94
Standard deviation 1.9
Values 2.6 5.3
[83]
THLE BGN
Mean 0.764
Standard deviation 0.37
Values 1 0.51
[84]
liver BGN
Mean 36.2
Standard deviation 29
Values 65 9.5 57 13
[85]
ref_hepatocyte VCAN
Mean 0.409
Standard deviation 0.32
Values 0.014 0.17 0.6 0.47 0.8
[86]
HepG2 VCAN
Mean 24.2
Standard deviation 5.2
Values 21 28
[87]
HepG2.C3A VCAN
Mean 0.601
Standard deviation 0.27
Values 0.41 0.79
[88]
HuH.7 VCAN
Mean 10
Standard deviation 9.3
Values 6.1 21 3.4
[89]
SNU475 VCAN
Mean 2.11
Standard deviation 1.7
Values 0.9 3.3
[90]
THLE VCAN
Mean 46.4
Standard deviation 11
Values 39 54
[91]
liver VCAN
Mean 8.26
Standard deviation 6.7
Values 4.5 8.5 2.4 18
[92]
ref_hepatocyte CHSY3
Mean 0.296
Standard deviation 0.37
Values 0 0.1 0 0.8 0.58
[93]
HepG2 CHSY3
Mean 0.275
Standard deviation 0.19
Values 0.14 0.41
[94]
HepG2.C3A CHSY3
Mean 0.0414
Standard deviation 0.017
Values 0.029 0.054
[95]
HuH.7 CHSY3
Mean 0.448
Standard deviation 0.01
Values 0.46 0.44 0.44
[96]
SNU475 CHSY3
Mean 0.0388
Standard deviation 0.0024
Values 0.037 0.041
[97]
THLE CHSY3
Mean 0.572
Standard deviation 0.29
Values 0.37 0.78
[98]
liver CHSY3
Mean 2.92
Standard deviation 2.4
Values 0.73 5.2 0.98 4.7
[99]
ref_hepatocyte CSGALNACT1
Mean 0.232
Standard deviation 0.15
Values 0.48 0.15 0.21 0.1 0.21
[100]
HepG2 CSGALNACT1
Mean 1.88
Standard deviation 0.056
Values 1.9 1.8
[101]
HepG2.C3A CSGALNACT1
Mean 6.31
Standard deviation 0.69
Values 6.8 5.8
[102]
HuH.7 CSGALNACT1
Mean 0.867
Standard deviation 0.22
Values 0.71 0.76 1.1
[103]
SNU475 CSGALNACT1
Mean 1.55
Standard deviation 0.56
Values 1.2 1.9
[104]
THLE CSGALNACT1
Mean 27.3
Standard deviation 4.9
Values 31 24
[105]
liver CSGALNACT1
Mean 2.32
Standard deviation 0.54
Values 2.4 1.7 2.1 3
[106]
ref_hepatocyte CSPG5
Mean 0.152
Standard deviation 0.19
Values 0 0.34 0 0.39 0.033
[107]
HepG2 CSPG5
Mean 0.145
Standard deviation 0.022
Values 0.16 0.13
[108]
HepG2.C3A CSPG5
Mean 0.0194
Standard deviation 0.027
Values 0.039 0
[109]
HuH.7 CSPG5
Mean 1.09
Standard deviation 0.56
Values 1.3 0.46 1.5
[110]
SNU475 CSPG5
Mean 0.62
Standard deviation 0.32
Values 0.39 0.85
[111]
THLE CSPG5
Mean 0.16
Standard deviation 0.016
Values 0.17 0.15
[112]
liver CSPG5
Mean 0.0462
Standard deviation 0.032
Values 0.024 0.043 0.026 0.093
[113]
ref_hepatocyte CHST11
Mean 0.097
Standard deviation 0.1
Values 0 0.06 0.062 0.095 0.27
[114]
HepG2 CHST11
Mean 0.327
Standard deviation 0.3
Values 0.54 0.12
[115]
HepG2.C3A CHST11
Mean 0.0107
Standard deviation 0.015
Values 0 0.021
[116]
HuH.7 CHST11
Mean 1
Standard deviation 0.39
Values 1.1 1.3 0.58
[117]
SNU475 CHST11
Mean 3.19
Standard deviation 2.7
Values 1.3 5.1
[118]
THLE CHST11
Mean 17.3
Standard deviation 4.1
Values 14 20
[119]
liver CHST11
Mean 2.22
Standard deviation 1.5
Values 1.1 3.1 0.8 4
[120]
ref_hepatocyte NCAN
Mean 0.0163
Standard deviation 0.036
Values 0 0 0.082 0 0
[121]
HepG2 NCAN
Mean 0.117
Standard deviation 0.12
Values 0.2 0.034
[122]
HepG2.C3A NCAN
Mean 0.0151
Standard deviation 0.0062
Values 0.019 0.011
[123]
HuH.7 NCAN
Mean 0.0731
Standard deviation 0.043
Values 0.041 0.12 0.056
[124]
SNU475 NCAN
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[125]
THLE NCAN
Mean 0.0207
Standard deviation 0.029
Values 0.041 0
[126]
liver NCAN
Mean 0.013
Standard deviation 0.015
Values 0.024 0.029 0 0
[127]
ref_hepatocyte CSPG4
Mean 0.0131
Standard deviation 0.018
Values 0.014 0 0.043 0 0.0081
[128]
HepG2 CSPG4
Mean 0.338
Standard deviation 0.09
Values 0.4 0.27
[129]
HepG2.C3A CSPG4
Mean 0.151
Standard deviation 0.062
Values 0.19 0.11
[130]
HuH.7 CSPG4
Mean 0.505
Standard deviation 0.16
Values 0.57 0.62 0.33
[131]
SNU475 CSPG4
Mean 3.45
Standard deviation 0.17
Values 3.6 3.3
[132]
THLE CSPG4
Mean 6.12
Standard deviation 2.4
Values 4.4 7.8
[133]
liver CSPG4
Mean 1.04
Standard deviation 1.2
Values 0.16 1.3 0.1 2.5
[134]
ref_hepatocyte BCAN
Mean 0.0065
Standard deviation 0.015
Values 0 0 0 0 0.033
[135]
HepG2 BCAN
Mean 4.23
Standard deviation 3.5
Values 6.7 1.8
[136]
HepG2.C3A BCAN
Mean 4.29
Standard deviation 0.91
Values 4.9 3.6
[137]
HuH.7 BCAN
Mean 1.21
Standard deviation 0.35
Values 1.3 1.5 0.83
[138]
SNU475 BCAN
Mean 1.96
Standard deviation 0.26
Values 2.1 1.8
[139]
THLE BCAN
Mean 0.527
Standard deviation 0.083
Values 0.59 0.47
[140]
liver BCAN
Mean 0.0604
Standard deviation 0.033
Values 0.071 0.029 0.1 0.04