REACTOME_CHOLINE_CATABOLISM Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 BHMT Betaine--homocysteine S-methyltransferase 1 [1] -4.79[2] -5.33[3] -8.99[4] -7.62[5] -14.33[6] -1.28[7]
2 ALDH7A1 Alpha-aminoadipic semialdehyde dehydrogenase [8] 2.04[9] 1.61[10] 1.62[11] 1.84[12] 2.28[13] -0.18[14]
3 DMGDH Dimethylglycine dehydrogenase, mitochondrial [15] -2.01[16] -2.38[17] -1.00[18] -0.49[19] -6.92[20] 0.68[21]
4 SARDH Sarcosine dehydrogenase, mitochondrial [22] 0.59[23] 0.62[24] 0.62[25] -3.78[26] -2.02[27] 1.51[28]
5 SLC44A1 Choline transporter-like protein 1 [29] 1.73[30] 1.70[31] 2.62[32] 3.05[33] 2.89[34] 1.40[35]
6 CHDH Choline dehydrogenase, mitochondrial [36] 2.23[37] 2.83[38] 1.17[39] -4.09[40] -4.34[41] 1.02[42]
[1]
ref_hepatocyte BHMT
Mean 117
Standard deviation 1.9e+02
Values 8.1 4.9 6.9 1.1e+02 4.5e+02
[2]
HepG2 BHMT
Mean 3.57
Standard deviation 0.19
Values 3.7 3.4
[3]
HepG2.C3A BHMT
Mean 2.82
Standard deviation 2.3
Values 1.2 4.4
[4]
HuH.7 BHMT
Mean 0.184
Standard deviation 0.018
Values 0.16 0.19 0.2
[5]
SNU475 BHMT
Mean 0.29
Standard deviation 0.11
Values 0.37 0.21
[6]
THLE BHMT
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[7]
liver BHMT
Mean 94.8
Standard deviation 50
Values 1.5e+02 69 1.2e+02 39
[8]
ref_hepatocyte ALDH7A1
Mean 17.3
Standard deviation 15
Values 24 6.2 1 16 39
[9]
HepG2 ALDH7A1
Mean 60.1
Standard deviation 16
Values 49 72
[10]
HepG2.C3A ALDH7A1
Mean 51.1
Standard deviation 14
Values 41 61
[11]
HuH.7 ALDH7A1
Mean 42.6
Standard deviation 10
Values 48 31 49
[12]
SNU475 ALDH7A1
Mean 30.3
Standard deviation 10
Values 38 23
[13]
THLE ALDH7A1
Mean 43.7
Standard deviation 3.2
Values 41 46
[14]
liver ALDH7A1
Mean 30
Standard deviation 18
Values 50 17 40 14
[15]
ref_hepatocyte DMGDH
Mean 16.7
Standard deviation 24
Values 2.9 2.5 0.82 19 58
[16]
HepG2 DMGDH
Mean 3.51
Standard deviation 0.46
Values 3.2 3.8
[17]
HepG2.C3A DMGDH
Mean 3.12
Standard deviation 0.38
Values 3.4 2.9
[18]
HuH.7 DMGDH
Mean 6.73
Standard deviation 2.1
Values 6.5 9 4.7
[19]
SNU475 DMGDH
Mean 5.82
Standard deviation 2.5
Values 7.6 4
[20]
THLE DMGDH
Mean 0.0722
Standard deviation 0.057
Values 0.11 0.032
[21]
liver DMGDH
Mean 52.7
Standard deviation 11
Values 40 62 47 62
[22]
ref_hepatocyte SARDH
Mean 15.9
Standard deviation 20
Values 4.6 0.76 0.51 32 42
[23]
HepG2 SARDH
Mean 20.2
Standard deviation 1.3
Values 19 21
[24]
HepG2.C3A SARDH
Mean 23.7
Standard deviation 3.8
Values 26 21
[25]
HuH.7 SARDH
Mean 19.6
Standard deviation 4.3
Values 24 16 18
[26]
SNU475 SARDH
Mean 0.567
Standard deviation 0.057
Values 0.61 0.53
[27]
THLE SARDH
Mean 2.05
Standard deviation 0.015
Values 2.1 2
[28]
liver SARDH
Mean 88.9
Standard deviation 39
Values 71 80 59 1.5e+02
[29]
ref_hepatocyte SLC44A1
Mean 13.6
Standard deviation 6.9
Values 21 12 4.1 19 12
[30]
HepG2 SLC44A1
Mean 38
Standard deviation 4.4
Values 35 41
[31]
HepG2.C3A SLC44A1
Mean 42.9
Standard deviation 0.65
Values 43 42
[32]
HuH.7 SLC44A1
Mean 67
Standard deviation 10
Values 65 78 58
[33]
SNU475 SLC44A1
Mean 55
Standard deviation 10
Values 62 48
[34]
THLE SLC44A1
Mean 52.4
Standard deviation 1.4
Values 53 51
[35]
liver SLC44A1
Mean 70.6
Standard deviation 35
Values 29 1e+02 94 55
[36]
ref_hepatocyte CHDH
Mean 8.63
Standard deviation 5.4
Values 13 2.5 3.1 11 14
[37]
HepG2 CHDH
Mean 34.2
Standard deviation 8.2
Values 28 40
[38]
HepG2.C3A CHDH
Mean 59.6
Standard deviation 4.1
Values 63 57
[39]
HuH.7 CHDH
Mean 15.6
Standard deviation 0.26
Values 16 16 15
[40]
SNU475 CHDH
Mean 0.247
Standard deviation 0.005
Values 0.25 0.24
[41]
THLE CHDH
Mean 0.222
Standard deviation 0.1
Values 0.3 0.15
[42]
liver CHDH
Mean 34.4
Standard deviation 9.9
Values 34 44 39 21