REACTOME_CHAPERONE_MEDIATED_AUTOPHAGY Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 EEF1A1 Elongation factor 1-alpha 1 [1] 1.02[2] 1.19[3] 1.38[4] 0.22[5] 0.62[6] 0.57[7]
2 UBB Polyubiquitin-B [8] -2.21[9] -2.94[10] -2.88[11] -2.03[12] -1.74[13] -0.85[14]
3 RPS27A Ubiquitin-40S ribosomal protein S27a [15] [16] [17] [18] [19] [20] [21]
4 UBC Polyubiquitin-C [22] -1.77[23] -2.19[24] -2.51[25] -1.17[26] -1.36[27] -0.40[28]
5 HSP90AB1 Heat shock protein HSP 90-beta [29] 0.22[30] -0.22[31] -1.11[32] 0.21[33] -0.59[34] -1.08[35]
6 HSPA8 Heat shock cognate 71 kDa protein [36] -0.33[37] -0.86[38] -1.64[39] 0.72[40] 0.24[41] -0.05[42]
7 HSP90AA1 Heat shock protein HSP 90-alpha [43] -0.66[44] -0.22[45] -1.07[46] 0.84[47] 0.35[48] -0.23[49]
8 PARK7 Protein/nucleic acid deglycase DJ-1 [50] -1.60[51] -1.32[52] -2.65[53] -1.03[54] -1.22[55] -0.61[56]
9 PLIN2 Perilipin-2 [57] 1.24[58] 0.55[59] -0.98[60] -2.11[61] 1.67[62] 2.35[63]
10 UBA52 Ubiquitin-60S ribosomal protein L40 [64] 0.67[65] 0.05[66] 1.00[67] 0.22[68] 0.86[69] 0.37[70]
11 VIM Vimentin [71] -8.36[72] -9.33[73] -3.76[74] 3.35[75] 2.60[76] -0.22[77]
12 LAMP2 Lysosome-associated membrane glycoprotein 2 [78] 0.11[79] -0.89[80] 0.65[81] 1.63[82] 1.56[83] 2.26[84]
13 HBB Hemoglobin subunit beta [85] [86] [87] [88] [89] [90] -0.62[91]
14 PLIN3 Perilipin-3 [92] 0.97[93] 0.29[94] -0.53[95] 0.93[96] 0.15[97] -0.16[98]
15 HDAC6 Histone deacetylase 6 [99] 0.64[100] 1.06[101] 1.07[102] 1.03[103] 0.33[104] 3.18[105]
16 RNASE1 Ribonuclease pancreatic [106] -5.69[107] [108] -8.32[109] -6.25[110] -5.55[111] 1.87[112]
17 IFT88 Intraflagellar transport protein 88 homolog [113] -0.98[114] 0.10[115] -0.43[116] 0.95[117] 0.21[118] 2.30[119]
18 ARL13B ADP-ribosylation factor-like protein 13B [120] -0.28[121] 0.33[122] 0.91[123] 1.57[124] 2.09[125] 1.90[126]
19 PCNT Pericentrin [127] 2.67[128] 2.58[129] 1.93[130] 4.21[131] 3.86[132] 4.87[133]
20 GFAP Glial fibrillary acidic protein [134] 2.38[135] 0.52[136] -0.20[137] 2.58[138] 3.46[139] 2.33[140]
21 CFTR Cystic fibrosis transmembrane conductance regulator [141] -2.19[142] -3.23[143] 0.24[144] 4.58[145] -3.19[146] 8.18[147]
22 CETN1 Centrin-1 [148] [149] [150] [151] [152] [153] [154]
[1]
ref_hepatocyte EEF1A1
Mean 1.53e+03
Standard deviation 5.3e+02
Values 2.4e+03 1.1e+03 1.2e+03 1.5e+03 1.4e+03
[2]
HepG2 EEF1A1
Mean 6.91e+03
Standard deviation 7.4e+02
Values 7.4e+03 6.4e+03
[3]
HepG2.C3A EEF1A1
Mean 1e+04
Standard deviation 2.5e+03
Values 1.2e+04 8.3e+03
[4]
HuH.7 EEF1A1
Mean 1.16e+04
Standard deviation 2.1e+03
Values 9.3e+03 1.3e+04 1.2e+04
[5]
SNU475 EEF1A1
Mean 1.94e+03
Standard deviation 3.8e+02
Values 2.2e+03 1.7e+03
[6]
THLE EEF1A1
Mean 3.24e+03
Standard deviation 6.5e+02
Values 2.8e+03 3.7e+03
[7]
liver EEF1A1
Mean 1.58e+03
Standard deviation 7.1e+02
Values 1.1e+03 2.6e+03 9.9e+02 1.7e+03
[8]
ref_hepatocyte UBB
Mean 764
Standard deviation 4.8e+02
Values 3.8e+02 3.5e+02 5.3e+02 1.2e+03 1.3e+03
[9]
HepG2 UBB
Mean 368
Standard deviation 39
Values 4e+02 3.4e+02
[10]
HepG2.C3A UBB
Mean 285
Standard deviation 14
Values 2.8e+02 3e+02
[11]
HuH.7 UBB
Mean 304
Standard deviation 40
Values 2.9e+02 2.7e+02 3.5e+02
[12]
SNU475 UBB
Mean 204
Standard deviation 3.3
Values 2.1e+02 2e+02
[13]
THLE UBB
Mean 315
Standard deviation 34
Values 2.9e+02 3.4e+02
[14]
liver UBB
Mean 296
Standard deviation 1.3e+02
Values 4.3e+02 2.1e+02 3.9e+02 1.5e+02
[15]
ref_hepatocyte RPS27A
Mean 499
Standard deviation 2.2e+02
Values 6.6e+02 6.1e+02 1.7e+02 6.8e+02 3.8e+02
[16]
HepG2 RPS27A
Missing
[17]
HepG2.C3A RPS27A
Missing
[18]
HuH.7 RPS27A
Missing
[19]
SNU475 RPS27A
Missing
[20]
THLE RPS27A
Missing
[21]
liver RPS27A
Missing
[22]
ref_hepatocyte UBC
Mean 480
Standard deviation 2.8e+02
Values 1.8e+02 3.5e+02 9.1e+02 5.8e+02 3.8e+02
[23]
HepG2 UBC
Mean 314
Standard deviation 38
Values 3.4e+02 2.9e+02
[24]
HepG2.C3A UBC
Mean 302
Standard deviation 41
Values 3.3e+02 2.7e+02
[25]
HuH.7 UBC
Mean 246
Standard deviation 64
Values 2.4e+02 3.1e+02 1.9e+02
[26]
SNU475 UBC
Mean 232
Standard deviation 63
Values 2.8e+02 1.9e+02
[27]
THLE UBC
Mean 257
Standard deviation 41
Values 2.3e+02 2.9e+02
[28]
liver UBC
Mean 254
Standard deviation 78
Values 2.2e+02 3.1e+02 3.3e+02 1.6e+02
[29]
ref_hepatocyte HSP90AB1
Mean 469
Standard deviation 3.2e+02
Values 8.1e+02 7.8e+02 4e+02 2.1e+02 1.4e+02
[30]
HepG2 HSP90AB1
Mean 1.22e+03
Standard deviation 89
Values 1.2e+03 1.3e+03
[31]
HepG2.C3A HSP90AB1
Mean 1.16e+03
Standard deviation 1.2e+02
Values 1.2e+03 1.1e+03
[32]
HuH.7 HSP90AB1
Mean 634
Standard deviation 9.5
Values 6.3e+02 6.2e+02 6.4e+02
[33]
SNU475 HSP90AB1
Mean 591
Standard deviation 65
Values 5.4e+02 6.4e+02
[34]
THLE HSP90AB1
Mean 431
Standard deviation 80
Values 3.7e+02 4.9e+02
[35]
liver HSP90AB1
Mean 156
Standard deviation 26
Values 1.5e+02 1.4e+02 1.9e+02 1.3e+02
[36]
ref_hepatocyte HSPA8
Mean 426
Standard deviation 1.7e+02
Values 2.7e+02 6.5e+02 5.6e+02 3.4e+02 3.1e+02
[37]
HepG2 HSPA8
Mean 753
Standard deviation 2.8e+02
Values 5.5e+02 9.5e+02
[38]
HepG2.C3A HSPA8
Mean 671
Standard deviation 1.8e+02
Values 5.4e+02 8e+02
[39]
HuH.7 HSPA8
Mean 398
Standard deviation 32
Values 4.3e+02 3.6e+02 4e+02
[40]
SNU475 HSPA8
Mean 762
Standard deviation 89
Values 7e+02 8.2e+02
[41]
THLE HSPA8
Mean 692
Standard deviation 1.9e+02
Values 5.6e+02 8.2e+02
[42]
liver HSPA8
Mean 287
Standard deviation 81
Values 2e+02 3.1e+02 2.5e+02 3.9e+02
[43]
ref_hepatocyte HSP90AA1
Mean 356
Standard deviation 2.5e+02
Values 5.4e+02 6.9e+02 1.3e+02 2.5e+02 1.7e+02
[44]
HepG2 HSP90AA1
Mean 503
Standard deviation 2.6e+02
Values 3.2e+02 6.9e+02
[45]
HepG2.C3A HSP90AA1
Mean 878
Standard deviation 5.2e+02
Values 5.1e+02 1.2e+03
[46]
HuH.7 HSP90AA1
Mean 494
Standard deviation 76
Values 5.4e+02 4.1e+02 5.4e+02
[47]
SNU475 HSP90AA1
Mean 696
Standard deviation 1.5e+02
Values 5.9e+02 8e+02
[48]
THLE HSP90AA1
Mean 627
Standard deviation 16
Values 6.4e+02 6.2e+02
[49]
liver HSP90AA1
Mean 212
Standard deviation 50
Values 2.7e+02 1.9e+02 2.4e+02 1.6e+02
[50]
ref_hepatocyte PARK7
Mean 139
Standard deviation 62
Values 89 1.4e+02 68 2.2e+02 1.8e+02
[51]
HepG2 PARK7
Mean 102
Standard deviation 1.2
Values 1e+02 1e+02
[52]
HepG2.C3A PARK7
Mean 159
Standard deviation 46
Values 1.3e+02 1.9e+02
[53]
HuH.7 PARK7
Mean 64.5
Standard deviation 25
Values 68 38 87
[54]
SNU475 PARK7
Mean 74.3
Standard deviation 17
Values 86 62
[55]
THLE PARK7
Mean 82.1
Standard deviation 16
Values 71 93
[56]
liver PARK7
Mean 63.5
Standard deviation 47
Values 1.1e+02 27 99 19
[57]
ref_hepatocyte PLIN2
Mean 85.3
Standard deviation 61
Values 1.2e+02 74 30 1.7e+02 33
[58]
HepG2 PLIN2
Mean 450
Standard deviation 31
Values 4.7e+02 4.3e+02
[59]
HepG2.C3A PLIN2
Mean 356
Standard deviation 99
Values 4.3e+02 2.9e+02
[60]
HuH.7 PLIN2
Mean 126
Standard deviation 50
Values 96 1.8e+02 99
[61]
SNU475 PLIN2
Mean 21.6
Standard deviation 11
Values 14 29
[62]
THLE PLIN2
Mean 373
Standard deviation 17
Values 3.9e+02 3.6e+02
[63]
liver PLIN2
Mean 303
Standard deviation 1.4e+02
Values 4.5e+02 1.8e+02 4e+02 1.9e+02
[64]
ref_hepatocyte UBA52
Mean 57.3
Standard deviation 43
Values 14 23 49 1.2e+02 81
[65]
HepG2 UBA52
Mean 203
Standard deviation 20
Values 2.2e+02 1.9e+02
[66]
HepG2.C3A UBA52
Mean 169
Standard deviation 3.3
Values 1.7e+02 1.7e+02
[67]
HuH.7 UBA52
Mean 334
Standard deviation 46
Values 3.4e+02 2.8e+02 3.7e+02
[68]
SNU475 UBA52
Mean 72.9
Standard deviation 11
Values 65 81
[69]
THLE UBA52
Mean 144
Standard deviation 15
Values 1.3e+02 1.5e+02
[70]
liver UBA52
Mean 51.7
Standard deviation 26
Values 79 32 68 28
[71]
ref_hepatocyte VIM
Mean 54.6
Standard deviation 63
Values 0.056 1.2e+02 1.3e+02 12 14
[72]
HepG2 VIM
Mean 0.371
Standard deviation 0.34
Values 0.61 0.13
[73]
HepG2.C3A VIM
Mean 0.244
Standard deviation 0.11
Values 0.17 0.32
[74]
HuH.7 VIM
Mean 11.7
Standard deviation 9.3
Values 7.7 22 5.1
[75]
SNU475 VIM
Mean 609
Standard deviation 37
Values 6.4e+02 5.8e+02
[76]
THLE VIM
Mean 455
Standard deviation 1.6e+02
Values 3.4e+02 5.7e+02
[77]
liver VIM
Mean 32.8
Standard deviation 5.9
Values 37 35 35 24
[78]
ref_hepatocyte LAMP2
Mean 33.8
Standard deviation 15
Values 45 38 8.4 34 43
[79]
HepG2 LAMP2
Mean 81.1
Standard deviation 1.5
Values 80 82
[80]
HepG2.C3A LAMP2
Mean 52.2
Standard deviation 1.8
Values 51 54
[81]
HuH.7 LAMP2
Mean 154
Standard deviation 18
Values 1.6e+02 1.7e+02 1.3e+02
[82]
SNU475 LAMP2
Mean 114
Standard deviation 15
Values 1.2e+02 1e+02
[83]
THLE LAMP2
Mean 138
Standard deviation 22
Values 1.2e+02 1.5e+02
[84]
liver LAMP2
Mean 113
Standard deviation 50
Values 1.6e+02 84 1.5e+02 58
[85]
ref_hepatocyte HBB
Mean 27.3
Standard deviation 31
Values 0 0 16 59 61
[86]
HepG2 HBB
Mean 0
Standard deviation 0
Values 0 0
[87]
HepG2.C3A HBB
Mean 0
Standard deviation 0
Values 0 0
[88]
HuH.7 HBB
Mean 0
Standard deviation 0
Values 0 0 0
[89]
SNU475 HBB
Mean 0
Standard deviation 0
Values 0 0
[90]
THLE HBB
Mean 0
Standard deviation 0
Values 0 0
[91]
liver HBB
Mean 12.4
Standard deviation 20
Values 3 4 42 0.4
[92]
ref_hepatocyte PLIN3
Mean 20.5
Standard deviation 11
Values 14 31 32 18 6.3
[93]
HepG2 PLIN3
Mean 89.3
Standard deviation 9.5
Values 96 83
[94]
HepG2.C3A PLIN3
Mean 71.8
Standard deviation 7.7
Values 77 66
[95]
HuH.7 PLIN3
Mean 41.3
Standard deviation 4.8
Values 46 36 42
[96]
SNU475 PLIN3
Mean 42.6
Standard deviation 3.1
Values 40 45
[97]
THLE PLIN3
Mean 31.3
Standard deviation 7.6
Values 26 37
[98]
liver PLIN3
Mean 12.8
Standard deviation 6.6
Values 17 7.5 20 6.9
[99]
ref_hepatocyte HDAC6
Mean 6.59
Standard deviation 5
Values 5.6 0.94 2.9 12 12
[100]
HepG2 HDAC6
Mean 22.9
Standard deviation 2.2
Values 25 21
[101]
HepG2.C3A HDAC6
Mean 39.4
Standard deviation 17
Values 51 28
[102]
HuH.7 HDAC6
Mean 40.3
Standard deviation 7
Values 36 48 36
[103]
SNU475 HDAC6
Mean 14.7
Standard deviation 3
Values 17 13
[104]
THLE HDAC6
Mean 11.4
Standard deviation 0.42
Values 12 11
[105]
liver HDAC6
Mean 41.8
Standard deviation 2.9
Values 40 40 46 41
[106]
ref_hepatocyte RNASE1
Mean 3.12
Standard deviation 3.6
Values 0 0.29 2.2 8.9 4.2
[107]
HepG2 RNASE1
Mean 0.135
Standard deviation 0.052
Values 0.097 0.17
[108]
HepG2.C3A RNASE1
Mean 0
Standard deviation 0
Values 0 0
[109]
HuH.7 RNASE1
Mean 0.0285
Standard deviation 0.029
Values 0.057 0 0.028
[110]
SNU475 RNASE1
Mean 0.0448
Standard deviation 0.037
Values 0.019 0.071
[111]
THLE RNASE1
Mean 0.092
Standard deviation 0.062
Values 0.14 0.048
[112]
liver RNASE1
Mean 7.96
Standard deviation 7.2
Values 13 2 15 1.6
[113]
ref_hepatocyte IFT88
Mean 2.89
Standard deviation 0.71
Values 2 3.6 2.2 3.2 3.3
[114]
HepG2 IFT88
Mean 3.25
Standard deviation 0.45
Values 2.9 3.6
[115]
HepG2.C3A IFT88
Mean 8.87
Standard deviation 1.7
Values 7.7 10
[116]
HuH.7 IFT88
Mean 6.24
Standard deviation 0.44
Values 6.3 5.8 6.6
[117]
SNU475 IFT88
Mean 6.08
Standard deviation 0.76
Values 6.6 5.5
[118]
THLE IFT88
Mean 4.6
Standard deviation 0.25
Values 4.4 4.8
[119]
liver IFT88
Mean 9.92
Standard deviation 1.7
Values 11 11 11 7.4
[120]
ref_hepatocyte ARL13B
Mean 1.38
Standard deviation 0.93
Values 1.2 2.9 1.4 0.49 0.92
[121]
HepG2 ARL13B
Mean 2.54
Standard deviation 0.94
Values 1.9 3.2
[122]
HepG2.C3A ARL13B
Mean 4.99
Standard deviation 2.4
Values 3.3 6.7
[123]
HuH.7 ARL13B
Mean 7.59
Standard deviation 1.7
Values 8.3 5.6 8.8
[124]
SNU475 ARL13B
Mean 4.49
Standard deviation 0.7
Values 4 5
[125]
THLE ARL13B
Mean 8.14
Standard deviation 0.088
Values 8.2 8.1
[126]
liver ARL13B
Mean 3.6
Standard deviation 0.74
Values 3.4 3.9 4.4 2.7
[127]
ref_hepatocyte PCNT
Mean 0.9
Standard deviation 0.2
Values 1 1.1 0.66 0.96 0.71
[128]
HepG2 PCNT
Mean 12.7
Standard deviation 4
Values 9.9 16
[129]
HepG2.C3A PCNT
Mean 15.4
Standard deviation 4.6
Values 12 19
[130]
HuH.7 PCNT
Mean 9.97
Standard deviation 2.9
Values 12 6.7 11
[131]
SNU475 PCNT
Mean 18.2
Standard deviation 0.56
Values 18 19
[132]
THLE PCNT
Mean 18
Standard deviation 3.6
Values 15 21
[133]
liver PCNT
Mean 18.4
Standard deviation 9.4
Values 11 29 10 24
[134]
ref_hepatocyte GFAP
Mean 0.0179
Standard deviation 0.025
Values 0.038 0 0 0.052 0
[135]
HepG2 GFAP
Mean 0.207
Standard deviation 0.0074
Values 0.21 0.2
[136]
HepG2.C3A GFAP
Mean 0.0736
Standard deviation 0.063
Values 0.029 0.12
[137]
HuH.7 GFAP
Mean 0.0454
Standard deviation 0.011
Values 0.041 0.058 0.037
[138]
SNU475 GFAP
Mean 0.116
Standard deviation 0.072
Values 0.065 0.17
[139]
THLE GFAP
Mean 0.272
Standard deviation 0.15
Values 0.38 0.16
[140]
liver GFAP
Mean 0.0628
Standard deviation 0.026
Values 0.024 0.071 0.077 0.079
[141]
ref_hepatocyte CFTR
Mean 0.0176
Standard deviation 0.025
Values 0 0.036 0 0.052 0
[142]
HepG2 CFTR
Mean 0.0086
Standard deviation 0.012
Values 0.017 0
[143]
HepG2.C3A CFTR
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[144]
HuH.7 CFTR
Mean 0.0604
Standard deviation 0.037
Values 0.041 0.1 0.037
[145]
SNU475 CFTR
Mean 0.458
Standard deviation 0.37
Values 0.72 0.2
[146]
THLE CFTR
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[147]
liver CFTR
Mean 3.57
Standard deviation 2.4
Values 2.5 3 1.6 7.1
[148]
ref_hepatocyte CETN1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[149]
HepG2 CETN1
Mean 0
Standard deviation 0
Values 0 0
[150]
HepG2.C3A CETN1
Mean 0
Standard deviation 0
Values 0 0
[151]
HuH.7 CETN1
Mean 0
Standard deviation 0
Values 0 0 0
[152]
SNU475 CETN1
Mean 0.0417
Standard deviation 0.059
Values 0.083 0
[153]
THLE CETN1
Mean 0
Standard deviation 0
Values 0 0
[154]
liver CETN1
Mean 0
Standard deviation 0
Values 0 0 0 0