REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 ACTB Actin, cytoplasmic 1 [1] -1.01[2] -0.80[3] -0.32[4] -1.11[5] -1.06[6] -0.11[7]
2 ACTG1 Actin, cytoplasmic 2 [8] 0.27[9] -0.16[10] -0.21[11] -1.30[12] -0.47[13] -0.86[14]
3 ITGB1 Integrin beta-1 [15] 0.61[16] 1.53[17] 1.52[18] 1.35[19] 1.86[20] 1.23[21]
4 ACTN1 Alpha-actinin-1 [22] 1.20[23] 1.21[24] 0.40[25] 1.60[26] 1.38[27] 1.10[28]
5 ILK Integrin-linked protein kinase [29] -0.42[30] 0.41[31] 0.19[32] -0.57[33] -1.03[34] -0.39[35]
6 VASP Vasodilator-stimulated phosphoprotein [36] 0.24[37] 0.74[38] 0.95[39] -0.35[40] -0.79[41] -1.85[42]
7 FERMT2 Fermitin family homolog 2 [43] -0.26[44] 0.48[45] 0.26[46] 1.13[47] 0.64[48] 1.39[49]
8 FLNA Filamin-A [50] 4.51[51] 3.86[52] 0.77[53] 5.43[54] 4.50[55] 3.23[56]
9 RSU1 Ras suppressor protein 1 [57] 0.42[58] 1.52[59] 0.20[60] 0.97[61] 0.58[62] 1.47[63]
10 PXN Paxillin [64] 1.38[65] 1.99[66] 1.88[67] 2.00[68] 2.39[69] 0.72[70]
11 LIMS1 LIM and senescent cell antigen-like-containing domain protein 1 [71] 0.60[72] 2.26[73] 1.72[74] 0.98[75] 1.34[76] 1.72[77]
12 LIMS2 LIM and senescent cell antigen-like-containing domain protein 2 [78] -0.29[79] -2.02[80] -5.09[81] -0.30[82] -3.76[83] 1.51[84]
13 TESK1 Dual specificity testis-specific protein kinase 1 [85] 0.24[86] 1.31[87] 0.13[88] -0.58[89] 0.24[90] 0.17[91]
14 FBLIM1 Filamin-binding LIM protein 1 [92] 3.64[93] 2.73[94] 2.54[95] 2.91[96] 2.78[97] 0.63[98]
15 PARVB Beta-parvin [99] -5.21[100] -6.94[101] 1.18[102] 0.12[103] 0.08[104] 0.77[105]
16 PARVA Alpha-parvin [106] 2.09[107] 2.35[108] 0.69[109] 3.37[110] 3.48[111] 3.56[112]
17 FLNC Filamin-C [113] -2.21[114] -2.76[115] -0.01[116] 6.76[117] 6.13[118] 0.73[119]
18 ARHGEF6 Rho guanine nucleotide exchange factor 6 [120] -5.64[121] -2.50[122] -3.26[123] 3.12[124] 2.07[125] 4.21[126]
[1]
ref_hepatocyte ACTB
Mean 1.3e+03
Standard deviation 6.4e+02
Values 1.6e+03 1.8e+03 1.9e+03 6.8e+02 5.5e+02
[2]
HepG2 ACTB
Mean 1.1e+03
Standard deviation 45
Values 1.1e+03 1.1e+03
[3]
HepG2.C3A ACTB
Mean 609
Standard deviation 6.4
Values 6e+02 6.1e+02
[4]
HuH.7 ACTB
Mean 903
Standard deviation 3.5e+02
Values 1.1e+03 5e+02 1.1e+03
[5]
SNU475 ACTB
Mean 1.2e+03
Standard deviation 5e+02
Values 1.6e+03 8.5e+02
[6]
THLE ACTB
Mean 1.03e+03
Standard deviation 3.2e+02
Values 8.1e+02 1.3e+03
[7]
liver ACTB
Mean 816
Standard deviation 6.8e+02
Values 1.2e+03 2.3e+02 1.6e+03 2.7e+02
[8]
ref_hepatocyte ACTG1
Mean 733
Standard deviation 4e+02
Values 1.1e+03 1e+03 9.5e+02 3.5e+02 2.4e+02
[9]
HepG2 ACTG1
Mean 1.5e+03
Standard deviation 1.8e+02
Values 1.6e+03 1.4e+03
[10]
HepG2.C3A ACTG1
Mean 534
Standard deviation 1.5e+02
Values 6.4e+02 4.3e+02
[11]
HuH.7 ACTG1
Mean 549
Standard deviation 1.6e+02
Values 6.7e+02 3.7e+02 6e+02
[12]
SNU475 ACTG1
Mean 591
Standard deviation 2.2e+02
Values 7.5e+02 4.3e+02
[13]
THLE ACTG1
Mean 872
Standard deviation 1.9e+02
Values 7.3e+02 1e+03
[14]
liver ACTG1
Mean 273
Standard deviation 78
Values 3.2e+02 1.9e+02 3.6e+02 2.2e+02
[15]
ref_hepatocyte ITGB1
Mean 128
Standard deviation 1e+02
Values 91 3e+02 1.4e+02 58 51
[16]
HepG2 ITGB1
Mean 333
Standard deviation 10
Values 3.4e+02 3.3e+02
[17]
HepG2.C3A ITGB1
Mean 301
Standard deviation 47
Values 2.7e+02 3.3e+02
[18]
HuH.7 ITGB1
Mean 317
Standard deviation 16
Values 3.3e+02 3.3e+02 3e+02
[19]
SNU475 ITGB1
Mean 648
Standard deviation 88
Values 7.1e+02 5.9e+02
[20]
THLE ITGB1
Mean 768
Standard deviation 1.5e+02
Values 6.6e+02 8.8e+02
[21]
liver ITGB1
Mean 204
Standard deviation 85
Values 1.2e+02 3.2e+02 2.1e+02 1.6e+02
[22]
ref_hepatocyte ACTN1
Mean 41
Standard deviation 28
Values 17 82 59 26 20
[23]
HepG2 ACTN1
Mean 160
Standard deviation 12
Values 1.7e+02 1.5e+02
[24]
HepG2.C3A ACTN1
Mean 77.3
Standard deviation 10
Values 85 70
[25]
HuH.7 ACTN1
Mean 46.8
Standard deviation 15
Values 62 32 46
[26]
SNU475 ACTN1
Mean 246
Standard deviation 54
Values 2.8e+02 2.1e+02
[27]
THLE ACTN1
Mean 177
Standard deviation 43
Values 1.5e+02 2.1e+02
[28]
liver ACTN1
Mean 59.6
Standard deviation 20
Values 44 54 89 51
[29]
ref_hepatocyte ILK
Mean 34.8
Standard deviation 22
Values 19 51 65 22 18
[30]
HepG2 ILK
Mean 44.1
Standard deviation 5.5
Values 40 48
[31]
HepG2.C3A ILK
Mean 37.7
Standard deviation 0.69
Values 38 37
[32]
HuH.7 ILK
Mean 34.3
Standard deviation 5.9
Values 34 29 40
[33]
SNU475 ILK
Mean 46.7
Standard deviation 5.1
Values 50 43
[34]
THLE ILK
Mean 28.3
Standard deviation 5.4
Values 24 32
[35]
liver ILK
Mean 18
Standard deviation 7.1
Values 20 12 27 13
[36]
ref_hepatocyte VASP
Mean 30.5
Standard deviation 26
Values 18 68 47 12 7.1
[37]
HepG2 VASP
Mean 60.9
Standard deviation 13
Values 70 52
[38]
HepG2.C3A VASP
Mean 41.5
Standard deviation 7.5
Values 47 36
[39]
HuH.7 VASP
Mean 50.8
Standard deviation 9.1
Values 53 41 59
[40]
SNU475 VASP
Mean 47.6
Standard deviation 1.5
Values 49 47
[41]
THLE VASP
Mean 29.1
Standard deviation 4.5
Values 26 32
[42]
liver VASP
Mean 5.7
Standard deviation 0.72
Values 5.9 6.2 4.6 6.1
[43]
ref_hepatocyte FERMT2
Mean 17.6
Standard deviation 11
Values 8.4 16 36 13 15
[44]
HepG2 FERMT2
Mean 24.8
Standard deviation 5.8
Values 21 29
[45]
HepG2.C3A FERMT2
Mean 19.9
Standard deviation 3.4
Values 17 22
[46]
HuH.7 FERMT2
Mean 18.1
Standard deviation 2.7
Values 17 21 16
[47]
SNU475 FERMT2
Mean 76.2
Standard deviation 7.4
Values 81 71
[48]
THLE FERMT2
Mean 45.2
Standard deviation 2.5
Values 43 47
[49]
liver FERMT2
Mean 31.2
Standard deviation 5.4
Values 35 35 23 32
[50]
ref_hepatocyte FLNA
Mean 15.1
Standard deviation 16
Values 15 40 17 0.88 2.3
[51]
HepG2 FLNA
Mean 584
Standard deviation 2.4e+02
Values 7.5e+02 4.1e+02
[52]
HepG2.C3A FLNA
Mean 179
Standard deviation 17
Values 1.9e+02 1.7e+02
[53]
HuH.7 FLNA
Mean 22.3
Standard deviation 8.8
Values 32 18 16
[54]
SNU475 FLNA
Mean 1.29e+03
Standard deviation 6.6e+02
Values 1.8e+03 8.3e+02
[55]
THLE FLNA
Mean 565
Standard deviation 1.5e+02
Values 4.6e+02 6.7e+02
[56]
liver FLNA
Mean 95.8
Standard deviation 81
Values 16 1.3e+02 44 1.9e+02
[57]
ref_hepatocyte RSU1
Mean 9.68
Standard deviation 5.8
Values 4.5 20 9.7 7.6 7.1
[58]
HepG2 RSU1
Mean 22
Standard deviation 4.8
Values 19 25
[59]
HepG2.C3A RSU1
Mean 22.7
Standard deviation 1.9
Values 21 24
[60]
HuH.7 RSU1
Mean 9.61
Standard deviation 2.1
Values 11 7.3 10
[61]
SNU475 RSU1
Mean 37.7
Standard deviation 3.2
Values 40 35
[62]
THLE RSU1
Mean 23.9
Standard deviation 5.3
Values 20 28
[63]
liver RSU1
Mean 18.2
Standard deviation 11
Values 27 8.7 29 7.9
[64]
ref_hepatocyte PXN
Mean 9.17
Standard deviation 8.7
Values 3.1 8.2 24 4 6.1
[65]
HepG2 PXN
Mean 40.5
Standard deviation 4
Values 43 38
[66]
HepG2.C3A PXN
Mean 29.7
Standard deviation 0.97
Values 30 29
[67]
HuH.7 PXN
Mean 29.2
Standard deviation 3.3
Values 33 27 27
[68]
SNU475 PXN
Mean 73
Standard deviation 6.8
Values 78 68
[69]
THLE PXN
Mean 79.6
Standard deviation 9.5
Values 73 86
[70]
liver PXN
Mean 10.2
Standard deviation 5.9
Values 16 3.9 14 6.6
[71]
ref_hepatocyte LIMS1
Mean 5.95
Standard deviation 2.8
Values 8.7 8.6 6.3 2.9 3.2
[72]
HepG2 LIMS1
Mean 15.3
Standard deviation 2.8
Values 13 17
[73]
HepG2.C3A LIMS1
Mean 23.3
Standard deviation 5.4
Values 19 27
[74]
HuH.7 LIMS1
Mean 16.9
Standard deviation 2.7
Values 20 16 15
[75]
SNU475 LIMS1
Mean 23.4
Standard deviation 0.92
Values 24 23
[76]
THLE LIMS1
Mean 24.9
Standard deviation 5.3
Values 21 29
[77]
liver LIMS1
Mean 13.2
Standard deviation 3.8
Values 18 11 15 9.3
[78]
ref_hepatocyte LIMS2
Mean 4.63
Standard deviation 3.7
Values 0.27 5 1.8 6.6 9.5
[79]
HepG2 LIMS2
Mean 6.41
Standard deviation 1.3
Values 7.4 5.5
[80]
HepG2.C3A LIMS2
Mean 0.932
Standard deviation 0.47
Values 1.3 0.6
[81]
HuH.7 LIMS2
Mean 0.118
Standard deviation 0.054
Values 0.11 0.17 0.066
[82]
SNU475 LIMS2
Mean 7.49
Standard deviation 5
Values 11 3.9
[83]
THLE LIMS2
Mean 0.564
Standard deviation 0.053
Values 0.53 0.6
[84]
liver LIMS2
Mean 8.94
Standard deviation 4.2
Values 13 3.8 12 7.2
[85]
ref_hepatocyte TESK1
Mean 3.91
Standard deviation 2.8
Values 1.4 2 8.1 5.3 2.7
[86]
HepG2 TESK1
Mean 7.81
Standard deviation 1.4
Values 8.8 6.8
[87]
HepG2.C3A TESK1
Mean 7.88
Standard deviation 3.1
Values 10 5.7
[88]
HuH.7 TESK1
Mean 3.69
Standard deviation 0.84
Values 3.2 4.7 3.2
[89]
SNU475 TESK1
Mean 5.18
Standard deviation 0.14
Values 5.1 5.3
[90]
THLE TESK1
Mean 7.62
Standard deviation 0.6
Values 7.2 8
[91]
liver TESK1
Mean 2.97
Standard deviation 0.98
Values 4.1 1.9 3.4 2.5
[92]
ref_hepatocyte FBLIM1
Mean 3.32
Standard deviation 3.1
Values 5.3 7.8 2.3 0.72 0.52
[93]
HepG2 FBLIM1
Mean 70.3
Standard deviation 7.1
Values 75 65
[94]
HepG2.C3A FBLIM1
Mean 18
Standard deviation 2.8
Values 20 16
[95]
HuH.7 FBLIM1
Mean 16.7
Standard deviation 1.2
Values 18 16 16
[96]
SNU475 FBLIM1
Mean 49.7
Standard deviation 3.6
Values 52 47
[97]
THLE FBLIM1
Mean 37.7
Standard deviation 1.8
Values 36 39
[98]
liver FBLIM1
Mean 3.47
Standard deviation 0.18
Values 3.3 3.4 3.7 3.4
[99]
ref_hepatocyte PARVB
Mean 3.24
Standard deviation 3
Values 0 3.4 7.3 4.7 0.79
[100]
HepG2 PARVB
Mean 0.149
Standard deviation 0.14
Values 0.25 0.051
[101]
HepG2.C3A PARVB
Mean 0.0215
Standard deviation 0.03
Values 0 0.043
[102]
HuH.7 PARVB
Mean 6.35
Standard deviation 1.8
Values 7 4.3 7.8
[103]
SNU475 PARVB
Mean 6.99
Standard deviation 2.3
Values 8.6 5.3
[104]
THLE PARVB
Mean 5.68
Standard deviation 1.8
Values 4.4 6.9
[105]
liver PARVB
Mean 3.74
Standard deviation 1.6
Values 2.1 3.8 5.8 3.2
[106]
ref_hepatocyte PARVA
Mean 2.3
Standard deviation 0.95
Values 0.78 2.6 2 2.9 3.2
[107]
HepG2 PARVA
Mean 16.7
Standard deviation 7
Values 12 22
[108]
HepG2.C3A PARVA
Mean 9.57
Standard deviation 2.9
Values 7.5 12
[109]
HuH.7 PARVA
Mean 3.2
Standard deviation 0.88
Values 4.1 2.4 3.1
[110]
SNU475 PARVA
Mean 47.3
Standard deviation 18
Values 60 35
[111]
THLE PARVA
Mean 42.3
Standard deviation 13
Values 33 52
[112]
liver PARVA
Mean 18.4
Standard deviation 1.1
Values 19 17 20 18
[113]
ref_hepatocyte FLNC
Mean 1.18
Standard deviation 1.6
Values 0.012 2.8 3 0.017 0.041
[114]
HepG2 FLNC
Mean 0.434
Standard deviation 0.14
Values 0.33 0.54
[115]
HepG2.C3A FLNC
Mean 0.143
Standard deviation 0.0045
Values 0.15 0.14
[116]
HuH.7 FLNC
Mean 1.02
Standard deviation 0.66
Values 1 1.7 0.36
[117]
SNU475 FLNC
Mean 255
Standard deviation 50
Values 2.9e+02 2.2e+02
[118]
THLE FLNC
Mean 137
Standard deviation 27
Values 1.2e+02 1.6e+02
[119]
liver FLNC
Mean 1.33
Standard deviation 2.1
Values 0.12 0.47 0.23 4.5
[120]
ref_hepatocyte ARHGEF6
Mean 0.462
Standard deviation 0.27
Values 0 0.5 0.49 0.61 0.71
[121]
HepG2 ARHGEF6
Mean 0.0157
Standard deviation 0.014
Values 0.0057 0.026
[122]
HepG2.C3A ARHGEF6
Mean 0.0667
Standard deviation 0.012
Values 0.058 0.075
[123]
HuH.7 ARHGEF6
Mean 0.0417
Standard deviation 0.02
Values 0.033 0.064 0.028
[124]
SNU475 ARHGEF6
Mean 7.96
Standard deviation 2.4
Values 9.7 6.3
[125]
THLE ARHGEF6
Mean 3.2
Standard deviation 0.92
Values 3.9 2.6
[126]
liver ARHGEF6
Mean 5.77
Standard deviation 1.8
Values 3.9 8.1 5 6