REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 ORC4 Origin recognition complex subunit 4 [1] -0.91[2] -0.17[3] -0.44[4] 0.08[5] -0.68[6] 2.01[7]
2 ORC5 Origin recognition complex subunit 5 [8] -1.95[9] -2.05[10] -1.46[11] -1.43[12] -1.68[13] -1.14[14]
3 ORC2 Origin recognition complex subunit 2 [15] -0.51[16] 0.01[17] -0.25[18] -0.98[19] -0.71[20] -1.39[21]
4 CDC6 Cell division control protein 6 homolog [22] 0.89[23] 0.02[24] 0.63[25] 0.28[26] 0.53[27] -3.03[28]
5 ORC6 Origin recognition complex subunit 6 [29] -0.21[30] -0.09[31] -0.86[32] -0.50[33] -0.27[34] -4.66[35]
6 ORC3 Origin recognition complex subunit 3 [36] -0.89[37] -0.12[38] 0.03[39] -0.74[40] 0.21[41] -0.71[42]
7 E2F1 Transcription factor E2F1 [43] 0.98[44] 0.39[45] 0.53[46] 0.58[47] 1.00[48] -4.58[49]
8 E2F3 Transcription factor E2F3 [50] 0.74[51] 0.14[52] -0.60[53] 1.34[54] 0.78[55] -1.13[56]
9 MCM8 DNA helicase MCM8 [57] 1.23[58] 1.50[59] 0.79[60] 1.32[61] 0.85[62] -1.33[63]
10 ORC1 Origin recognition complex subunit 1 [64] 0.58[65] 0.17[66] 1.68[67] -0.01[68] 0.54[69] -3.07[70]
11 E2F2 Transcription factor E2F2 [71] 3.27[72] 3.73[73] 3.25[74] 2.77[75] 3.08[76] 0.46[77]
[1]
ref_hepatocyte ORC4
Mean 7.34
Standard deviation 1.8
Values 9.4 4.6 8.6 6.9 7.2
[2]
HepG2 ORC4
Mean 16.9
Standard deviation 4.9
Values 13 20
[3]
HepG2.C3A ORC4
Mean 34.1
Standard deviation 8.3
Values 28 40
[4]
HuH.7 ORC4
Mean 27
Standard deviation 4
Values 28 31 23
[5]
SNU475 ORC4
Mean 34.9
Standard deviation 3.4
Values 32 37
[6]
THLE ORC4
Mean 23.3
Standard deviation 2.6
Values 25 21
[7]
liver ORC4
Mean 81.8
Standard deviation 55
Values 38 1.4e+02 33 1.2e+02
[8]
ref_hepatocyte ORC5
Mean 6.5
Standard deviation 1.9
Values 3.5 7.8 7.3 8.2 5.7
[9]
HepG2 ORC5
Mean 7.28
Standard deviation 2.2
Values 5.8 8.8
[10]
HepG2.C3A ORC5
Mean 8.23
Standard deviation 4.9
Values 4.8 12
[11]
HuH.7 ORC5
Mean 11.8
Standard deviation 2.5
Values 13 9 14
[12]
SNU475 ORC5
Mean 10.8
Standard deviation 1.4
Values 9.8 12
[13]
THLE ORC5
Mean 10.3
Standard deviation 0.9
Values 9.6 11
[14]
liver ORC5
Mean 8.17
Standard deviation 1.7
Values 7.3 8.1 11 6.7
[15]
ref_hepatocyte ORC2
Mean 5.18
Standard deviation 5.6
Values 14 7.4 2.6 0.85 0.94
[16]
HepG2 ORC2
Mean 15.7
Standard deviation 4.5
Values 13 19
[17]
HepG2.C3A ORC2
Mean 27.2
Standard deviation 6.2
Values 23 32
[18]
HuH.7 ORC2
Mean 21.7
Standard deviation 4
Values 24 17 24
[19]
SNU475 ORC2
Mean 11.7
Standard deviation 1.6
Values 13 11
[20]
THLE ORC2
Mean 16.1
Standard deviation 1.1
Values 15 17
[21]
liver ORC2
Mean 5.45
Standard deviation 2.1
Values 6.1 5.5 2.6 7.7
[22]
ref_hepatocyte CDC6
Mean 4.53
Standard deviation 4.6
Values 11 8.2 1.9 1.2 0.8
[23]
HepG2 CDC6
Mean 36.3
Standard deviation 14
Values 26 46
[24]
HepG2.C3A CDC6
Mean 24
Standard deviation 17
Values 12 36
[25]
HuH.7 CDC6
Mean 35
Standard deviation 18
Values 43 15 47
[26]
SNU475 CDC6
Mean 24.6
Standard deviation 9.5
Values 18 31
[27]
THLE CDC6
Mean 33.3
Standard deviation 6.1
Values 29 38
[28]
liver CDC6
Mean 1.54
Standard deviation 0.85
Values 0.42 2.4 2 1.4
[29]
ref_hepatocyte ORC6
Mean 4.29
Standard deviation 5.9
Values 14 6.1 0.59 0.53 0.4
[30]
HepG2 ORC6
Mean 16
Standard deviation 4.8
Values 13 19
[31]
HepG2.C3A ORC6
Mean 21.1
Standard deviation 15
Values 11 32
[32]
HuH.7 ORC6
Mean 11.8
Standard deviation 5.5
Values 12 6.2 17
[33]
SNU475 ORC6
Mean 13.6
Standard deviation 0.87
Values 13 14
[34]
THLE ORC6
Mean 18.1
Standard deviation 2.6
Values 16 20
[35]
liver ORC6
Mean 0.47
Standard deviation 0.32
Values 0.26 0.46 0.92 0.24
[36]
ref_hepatocyte ORC3
Mean 3.83
Standard deviation 0.95
Values 4.8 3 4.9 3.1 3.3
[37]
HepG2 ORC3
Mean 8.96
Standard deviation 5.2
Values 5.3 13
[38]
HepG2.C3A ORC3
Mean 18.4
Standard deviation 9
Values 12 25
[39]
HuH.7 ORC3
Mean 19.5
Standard deviation 5.8
Values 24 13 21
[40]
SNU475 ORC3
Mean 10.2
Standard deviation 0.75
Values 9.7 11
[41]
THLE ORC3
Mean 22.5
Standard deviation 0.42
Values 23 22
[42]
liver ORC3
Mean 6.5
Standard deviation 1.7
Values 6.9 6.4 8.4 4.3
[43]
ref_hepatocyte E2F1
Mean 2.5
Standard deviation 3.1
Values 7.9 2.2 0.64 1.2 0.54
[44]
HepG2 E2F1
Mean 21.3
Standard deviation 1.8
Values 20 23
[45]
HepG2.C3A E2F1
Mean 17.2
Standard deviation 4.9
Values 14 21
[46]
HuH.7 E2F1
Mean 18
Standard deviation 12
Values 21 5.1 28
[47]
SNU475 E2F1
Mean 16.7
Standard deviation 4.8
Values 13 20
[48]
THLE E2F1
Mean 25.4
Standard deviation 2.4
Values 24 27
[49]
liver E2F1
Mean 0.29
Standard deviation 0.19
Values 0.12 0.49 0.41 0.15
[50]
ref_hepatocyte E2F3
Mean 2.21
Standard deviation 1.5
Values 2.9 4 2.9 0.72 0.6
[51]
HepG2 E2F3
Mean 16
Standard deviation 1.7
Values 15 17
[52]
HepG2.C3A E2F3
Mean 12.7
Standard deviation 3.5
Values 10 15
[53]
HuH.7 E2F3
Mean 7.25
Standard deviation 0.87
Values 7.9 6.3 7.6
[54]
SNU475 E2F3
Mean 25
Standard deviation 1.3
Values 24 26
[55]
THLE E2F3
Mean 19.2
Standard deviation 2.8
Values 17 21
[56]
liver E2F3
Mean 2.79
Standard deviation 0.85
Values 3 2.8 3.7 1.6
[57]
ref_hepatocyte MCM8
Mean 1.68
Standard deviation 1.7
Values 3.8 3.2 0.45 0.49 0.46
[58]
HepG2 MCM8
Mean 16.9
Standard deviation 9.8
Values 10 24
[59]
HepG2.C3A MCM8
Mean 24.7
Standard deviation 16
Values 14 36
[60]
HuH.7 MCM8
Mean 14.5
Standard deviation 7.7
Values 22 6.3 15
[61]
SNU475 MCM8
Mean 18.7
Standard deviation 3.3
Values 16 21
[62]
THLE MCM8
Mean 15.3
Standard deviation 1.1
Values 15 16
[63]
liver MCM8
Mean 1.84
Standard deviation 1.3
Values 0.8 3.4 0.82 2.3
[64]
ref_hepatocyte ORC1
Mean 1.51
Standard deviation 1.9
Values 4.6 1.8 0.38 0.4 0.31
[65]
HepG2 ORC1
Mean 9.76
Standard deviation 4.5
Values 6.6 13
[66]
HepG2.C3A ORC1
Mean 8.91
Standard deviation 3.7
Values 6.3 11
[67]
HuH.7 ORC1
Mean 24.2
Standard deviation 9.6
Values 31 13 29
[68]
SNU475 ORC1
Mean 6.72
Standard deviation 3.5
Values 4.2 9.2
[69]
THLE ORC1
Mean 11.2
Standard deviation 2.9
Values 9.2 13
[70]
liver ORC1
Mean 0.5
Standard deviation 0.15
Values 0.47 0.56 0.67 0.3
[71]
ref_hepatocyte E2F2
Mean 0.16
Standard deviation 0.14
Values 0.34 0.25 0.0027 0.15 0.065
[72]
HepG2 E2F2
Mean 6.69
Standard deviation 1.2
Values 5.8 7.5
[73]
HepG2.C3A E2F2
Mean 11.1
Standard deviation 5.8
Values 7 15
[74]
HuH.7 E2F2
Mean 7.58
Standard deviation 4.8
Values 11 2 9.9
[75]
SNU475 E2F2
Mean 4.87
Standard deviation 1.9
Values 3.6 6.2
[76]
THLE E2F2
Mean 6.85
Standard deviation 0.93
Values 6.2 7.5
[77]
liver E2F2
Mean 0.607
Standard deviation 0.45
Values 1.3 0.49 0.41 0.26