REACTOME_CD209_DC_SIGN_SIGNALING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 RELA Transcription factor p65 [1] -0.22[2] -0.58[3] -1.07[4] -0.46[5] -0.76[6] -1.36[7]
2 PRKACA cAMP-dependent protein kinase catalytic subunit alpha [8] -0.51[9] -0.55[10] -1.17[11] -0.88[12] -0.49[13] -1.26[14]
3 RAF1 RAF proto-oncogene serine/threonine-protein kinase [15] -0.41[16] 0.14[17] 0.78[18] -0.59[19] 0.07[20] 0.62[21]
4 NRAS GTPase NRas [22] 0.28[23] 0.86[24] 0.64[25] 0.59[26] -0.04[27] -0.73[28]
5 HRAS GTPase HRas [29] -1.36[30] -1.92[31] -3.34[32] -1.35[33] -1.78[34] -3.14[35]
6 PAK2 Serine/threonine-protein kinase PAK 2 [36] 1.10[37] 0.99[38] 0.65[39] 0.35[40] 0.69[41] 0.88[42]
7 ICAM3 Intercellular adhesion molecule 3 [43] -2.39[44] -1.31[45] -2.03[46] -4.16[47] -3.87[48] -0.46[49]
8 KRAS GTPase KRas [50] -0.87[51] -0.74[52] 0.23[53] 0.40[54] -0.15[55] 0.19[56]
9 NFKB1 Nuclear factor NF-kappa-B p105 subunit [57] 0.32[58] 0.14[59] -0.70[60] -0.65[61] 0.05[62] -0.03[63]
10 LYN Tyrosine-protein kinase Lyn [64] -1.21[65] -1.25[66] -1.34[67] 0.65[68] -0.80[69] -0.47[70]
11 RELB Transcription factor RelB [71] -0.64[72] -0.91[73] -1.29[74] -1.42[75] -0.40[76] -2.99[77]
12 PRKACB cAMP-dependent protein kinase catalytic subunit beta [78] -1.18[79] -0.26[80] 0.39[81] 1.83[82] 0.48[83] 1.23[84]
13 EP300 Histone acetyltransferase p300 [85] 2.37[86] 2.11[87] 2.37[88] 2.17[89] 2.01[90] 2.27[91]
14 PAK1 Serine/threonine-protein kinase PAK 1 [92] -0.36[93] -0.98[94] 0.80[95] -2.26[96] 1.31[97] -0.21[98]
15 FYN Tyrosine-protein kinase Fyn [99] 0.59[100] -7.86[101] 0.07[102] 1.07[103] 2.39[104] 0.49[105]
16 CREBBP CREB-binding protein [106] 2.55[107] 1.91[108] 1.89[109] 2.35[110] 2.15[111] 2.75[112]
17 ICAM2 Intercellular adhesion molecule 2 [113] -0.16[114] -0.32[115] -3.53[116] -5.29[117] -10.31[118] -0.74[119]
18 RPS6KA5 Ribosomal protein S6 kinase alpha-5 [120] [121] [122] [123] [124] [125] [126]
19 CD209 CD209 antigen [127] -2.83[128] -1.92[129] -3.02[130] -2.54[131] -3.75[132] 2.71[133]
20 PAK3 Serine/threonine-protein kinase PAK 3 [134] -6.76[135] [136] [137] -2.01[138] -0.49[139] 0.30[140]
21 PRKACG cAMP-dependent protein kinase catalytic subunit gamma [141] [142] [143] [144] [145] [146] [147]
[1]
ref_hepatocyte RELA
Mean 16
Standard deviation 11
Values 9.8 12 35 15 8.1
[2]
HepG2 RELA
Mean 38.7
Standard deviation 4.7
Values 42 35
[3]
HepG2.C3A RELA
Mean 24.3
Standard deviation 6.4
Values 29 20
[4]
HuH.7 RELA
Mean 25.6
Standard deviation 2.6
Values 29 25 23
[5]
SNU475 RELA
Mean 28.2
Standard deviation 0.33
Values 28 28
[6]
THLE RELA
Mean 29.7
Standard deviation 4
Values 27 32
[7]
liver RELA
Mean 12.3
Standard deviation 8.7
Values 19 4.1 20 5.7
[8]
ref_hepatocyte PRKACA
Mean 15.8
Standard deviation 8.3
Values 7.6 11 11 27 23
[9]
HepG2 PRKACA
Mean 31.2
Standard deviation 2.7
Values 29 33
[10]
HepG2.C3A PRKACA
Mean 24.6
Standard deviation 3.5
Values 27 22
[11]
HuH.7 PRKACA
Mean 23.6
Standard deviation 5.7
Values 27 17 27
[12]
SNU475 PRKACA
Mean 21
Standard deviation 3.3
Values 23 19
[13]
THLE PRKACA
Mean 35.4
Standard deviation 5.3
Values 32 39
[14]
liver PRKACA
Mean 13.1
Standard deviation 4.9
Values 18 8.8 16 8.9
[15]
ref_hepatocyte RAF1
Mean 15.5
Standard deviation 5.7
Values 6 14 20 20 17
[16]
HepG2 RAF1
Mean 32.7
Standard deviation 5.2
Values 29 36
[17]
HepG2.C3A RAF1
Mean 38.6
Standard deviation 2.8
Values 41 37
[18]
HuH.7 RAF1
Mean 89
Standard deviation 4.2
Values 85 93 89
[19]
SNU475 RAF1
Mean 25
Standard deviation 4.6
Values 22 28
[20]
THLE RAF1
Mean 50.9
Standard deviation 5.2
Values 47 55
[21]
liver RAF1
Mean 47
Standard deviation 3.6
Values 51 42 49 46
[22]
ref_hepatocyte NRAS
Mean 14.4
Standard deviation 13
Values 32 23 9.3 3.3 4.6
[23]
HepG2 NRAS
Mean 49.3
Standard deviation 10
Values 42 57
[24]
HepG2.C3A NRAS
Mean 59.2
Standard deviation 18
Values 47 72
[25]
HuH.7 NRAS
Mean 75.6
Standard deviation 9.1
Values 86 70 71
[26]
SNU475 NRAS
Mean 52.9
Standard deviation 9.2
Values 59 46
[27]
THLE NRAS
Mean 44
Standard deviation 8.9
Values 38 50
[28]
liver NRAS
Mean 17.2
Standard deviation 2.6
Values 14 21 18 16
[29]
ref_hepatocyte HRAS
Mean 11.6
Standard deviation 9
Values 4 27 11 7.4 8.8
[30]
HepG2 HRAS
Mean 12.7
Standard deviation 1.1
Values 14 12
[31]
HepG2.C3A HRAS
Mean 6.96
Standard deviation 1.3
Values 6 7.9
[32]
HuH.7 HRAS
Mean 3.85
Standard deviation 1.6
Values 3.6 2.4 5.6
[33]
SNU475 HRAS
Mean 11
Standard deviation 0.62
Values 11 11
[34]
THLE HRAS
Mean 10.7
Standard deviation 2.3
Values 9.1 12
[35]
liver HRAS
Mean 2.6
Standard deviation 1.6
Values 4.1 1.1 3.8 1.4
[36]
ref_hepatocyte PAK2
Mean 10.9
Standard deviation 2.8
Values 11 15 11 7.6 9.9
[37]
HepG2 PAK2
Mean 65.6
Standard deviation 14
Values 56 75
[38]
HepG2.C3A PAK2
Mean 49.1
Standard deviation 0.79
Values 49 50
[39]
HuH.7 PAK2
Mean 57.7
Standard deviation 11
Values 66 61 46
[40]
SNU475 PAK2
Mean 33.8
Standard deviation 4.3
Values 37 31
[41]
THLE PAK2
Mean 55.3
Standard deviation 9.9
Values 48 62
[42]
liver PAK2
Mean 39.9
Standard deviation 5.7
Values 44 41 43 32
[43]
ref_hepatocyte ICAM3
Mean 9.73
Standard deviation 7.3
Values 2.2 3 10 14 19
[44]
HepG2 ICAM3
Mean 5.24
Standard deviation 1.1
Values 4.5 6
[45]
HepG2.C3A ICAM3
Mean 8.9
Standard deviation 0.34
Values 8.7 9.1
[46]
HuH.7 ICAM3
Mean 8.04
Standard deviation 1.5
Values 9.2 6.3 8.7
[47]
SNU475 ICAM3
Mean 1.32
Standard deviation 0.24
Values 1.2 1.5
[48]
THLE ICAM3
Mean 2.09
Standard deviation 0.24
Values 1.9 2.3
[49]
liver ICAM3
Mean 14
Standard deviation 9.9
Values 26 5.7 19 5.9
[50]
ref_hepatocyte KRAS
Mean 8.97
Standard deviation 7.9
Values 18 17 5.4 1.7 2.7
[51]
HepG2 KRAS
Mean 13.9
Standard deviation 3.1
Values 12 16
[52]
HepG2.C3A KRAS
Mean 12.2
Standard deviation 2.3
Values 11 14
[53]
HuH.7 KRAS
Mean 35.4
Standard deviation 4.8
Values 40 30 36
[54]
SNU475 KRAS
Mean 28.7
Standard deviation 5.5
Values 33 25
[55]
THLE KRAS
Mean 25.4
Standard deviation 1.5
Values 24 26
[56]
liver KRAS
Mean 20.4
Standard deviation 8.7
Values 33 16 19 14
[57]
ref_hepatocyte NFKB1
Mean 6.35
Standard deviation 3.5
Values 3 6.7 12 5.3 4.7
[58]
HepG2 NFKB1
Mean 22.3
Standard deviation 5.4
Values 18 26
[59]
HepG2.C3A NFKB1
Mean 15.9
Standard deviation 1
Values 15 17
[60]
HuH.7 NFKB1
Mean 13.2
Standard deviation 0.86
Values 14 12 13
[61]
SNU475 NFKB1
Mean 9.83
Standard deviation 0.38
Values 9.6 10
[62]
THLE NFKB1
Mean 20.7
Standard deviation 5.3
Values 17 24
[63]
liver NFKB1
Mean 12.3
Standard deviation 4.6
Values 9.7 15 7.2 17
[64]
ref_hepatocyte LYN
Mean 5.33
Standard deviation 4.4
Values 0.29 6.8 12 3.7 3.8
[65]
HepG2 LYN
Mean 6.48
Standard deviation 1
Values 5.8 7.2
[66]
HepG2.C3A LYN
Mean 5.11
Standard deviation 2.1
Values 3.6 6.6
[67]
HuH.7 LYN
Mean 7.08
Standard deviation 0.67
Values 7.4 7.5 6.3
[68]
SNU475 LYN
Mean 20.4
Standard deviation 4.4
Values 17 23
[69]
THLE LYN
Mean 9.65
Standard deviation 1.4
Values 8.7 11
[70]
liver LYN
Mean 7.66
Standard deviation 1.7
Values 7.2 9.4 5.5 8.6
[71]
ref_hepatocyte RELB
Mean 4.03
Standard deviation 4.2
Values 1.3 4.6 11 1.6 1.6
[72]
HepG2 RELB
Mean 7.29
Standard deviation 3.8
Values 10 4.6
[73]
HepG2.C3A RELB
Mean 4.85
Standard deviation 2.7
Values 6.7 3
[74]
HuH.7 RELB
Mean 5.53
Standard deviation 4
Values 3.1 10 3.3
[75]
SNU475 RELB
Mean 3.66
Standard deviation 1.3
Values 2.7 4.6
[76]
THLE RELB
Mean 9.59
Standard deviation 0.74
Values 9.1 10
[77]
liver RELB
Mean 1.01
Standard deviation 0.18
Values 1 0.84 1.3 0.91
[78]
ref_hepatocyte PRKACB
Mean 2.75
Standard deviation 1.3
Values 2.1 3.1 1.4 2.4 4.8
[79]
HepG2 PRKACB
Mean 3.41
Standard deviation 1.6
Values 2.3 4.6
[80]
HepG2.C3A PRKACB
Mean 5.2
Standard deviation 0.9
Values 4.6 5.8
[81]
HuH.7 PRKACB
Mean 12.2
Standard deviation 3.4
Values 11 16 9.5
[82]
SNU475 PRKACB
Mean 23.8
Standard deviation 4.4
Values 27 21
[83]
THLE PRKACB
Mean 12.1
Standard deviation 0.96
Values 13 11
[84]
liver PRKACB
Mean 12.8
Standard deviation 2
Values 12 14 14 10
[85]
ref_hepatocyte EP300
Mean 2.46
Standard deviation 1.2
Values 3 1.8 4.4 1.4 1.8
[86]
HepG2 EP300
Mean 35.9
Standard deviation 5.7
Values 32 40
[87]
HepG2.C3A EP300
Mean 24.1
Standard deviation 1.4
Values 23 25
[88]
HuH.7 EP300
Mean 43
Standard deviation 15
Values 55 48 26
[89]
SNU475 EP300
Mean 26.9
Standard deviation 1.3
Values 28 26
[90]
THLE EP300
Mean 31.2
Standard deviation 11
Values 23 39
[91]
liver EP300
Mean 23.6
Standard deviation 8
Values 20 27 15 33
[92]
ref_hepatocyte PAK1
Mean 2.3
Standard deviation 0.59
Values 1.7 3 2.9 2.1 1.9
[93]
HepG2 PAK1
Mean 5.05
Standard deviation 1.5
Values 6.1 4
[94]
HepG2.C3A PAK1
Mean 2.65
Standard deviation 0.51
Values 3 2.3
[95]
HuH.7 PAK1
Mean 13.5
Standard deviation 2.2
Values 12 16 12
[96]
SNU475 PAK1
Mean 1.17
Standard deviation 0.24
Values 1 1.3
[97]
THLE PAK1
Mean 18
Standard deviation 0.72
Values 18 17
[98]
liver PAK1
Mean 3.94
Standard deviation 1.1
Values 5.3 4 3.9 2.6
[99]
ref_hepatocyte FYN
Mean 2.1
Standard deviation 2.2
Values 2.2 0.039 0.23 2.6 5.5
[100]
HepG2 FYN
Mean 8.91
Standard deviation 0.7
Values 9.4 8.4
[101]
HepG2.C3A FYN
Mean 0.0204
Standard deviation 0.0014
Values 0.019 0.021
[102]
HuH.7 FYN
Mean 7.43
Standard deviation 2.2
Values 8.9 4.8 8.5
[103]
SNU475 FYN
Mean 10.7
Standard deviation 2.5
Values 12 8.9
[104]
THLE FYN
Mean 34.5
Standard deviation 4.9
Values 38 31
[105]
liver FYN
Mean 5.84
Standard deviation 2.1
Values 8.9 4.4 5.1 5
[106]
ref_hepatocyte CREBBP
Mean 1.78
Standard deviation 0.69
Values 1.8 0.72 2.6 1.9 1.9
[107]
HepG2 CREBBP
Mean 29.3
Standard deviation 2.8
Values 27 31
[108]
HepG2.C3A CREBBP
Mean 15.2
Standard deviation 1
Values 16 14
[109]
HuH.7 CREBBP
Mean 22.2
Standard deviation 7.2
Values 28 24 14
[110]
SNU475 CREBBP
Mean 22.1
Standard deviation 0.2
Values 22 22
[111]
THLE CREBBP
Mean 24.9
Standard deviation 7.3
Values 20 30
[112]
liver CREBBP
Mean 23.8
Standard deviation 6
Values 30 21 17 28
[113]
ref_hepatocyte ICAM2
Mean 1.08
Standard deviation 0.96
Values 2.1 0.1 0 1.6 1.5
[114]
HepG2 ICAM2
Mean 2.71
Standard deviation 0.82
Values 3.3 2.1
[115]
HepG2.C3A ICAM2
Mean 1.95
Standard deviation 0.86
Values 1.3 2.6
[116]
HuH.7 ICAM2
Mean 0.313
Standard deviation 0.073
Values 0.3 0.25 0.39
[117]
SNU475 ICAM2
Mean 0.0667
Standard deviation 0.042
Values 0.037 0.096
[118]
THLE ICAM2
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[119]
liver ICAM2
Mean 1.28
Standard deviation 0.82
Values 1.9 0.49 2 0.66
[120]
ref_hepatocyte RPS6KA5
Mean 0.385
Standard deviation 0.19
Values 0.21 0.42 0.65 0.18 0.46
[121]
HepG2 RPS6KA5
Missing
[122]
HepG2.C3A RPS6KA5
Missing
[123]
HuH.7 RPS6KA5
Missing
[124]
SNU475 RPS6KA5
Missing
[125]
THLE RPS6KA5
Missing
[126]
liver RPS6KA5
Missing
[127]
ref_hepatocyte CD209
Mean 0.175
Standard deviation 0.16
Values 0 0 0.27 0.34 0.27
[128]
HepG2 CD209
Mean 0.0694
Standard deviation 0.017
Values 0.057 0.082
[129]
HepG2.C3A CD209
Mean 0.105
Standard deviation 0.079
Values 0.049 0.16
[130]
HuH.7 CD209
Mean 0.0723
Standard deviation 0.038
Values 0.033 0.11 0.075
[131]
SNU475 CD209
Mean 0.073
Standard deviation 0.011
Values 0.065 0.081
[132]
THLE CD209
Mean 0.0408
Standard deviation 0.043
Values 0.071 0.011
[133]
liver CD209
Mean 2.27
Standard deviation 1.7
Values 0.71 3.7 3.7 0.95
[134]
ref_hepatocyte PAK3
Mean 0.0826
Standard deviation 0.14
Values 0 0 0.33 0 0.081
[135]
HepG2 PAK3
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[136]
HepG2.C3A PAK3
Mean 0
Standard deviation 0
Values 0 0
[137]
HuH.7 PAK3
Mean 0
Standard deviation 0
Values 0 0 0
[138]
SNU475 PAK3
Mean 0.05
Standard deviation 0.051
Values 0.014 0.086
[139]
THLE PAK3
Mean 0.185
Standard deviation 0.065
Values 0.23 0.14
[140]
liver PAK3
Mean 0.202
Standard deviation 0.041
Values 0.24 0.14 0.21 0.23
[141]
ref_hepatocyte PRKACG
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[142]
HepG2 PRKACG
Mean 0.00214
Standard deviation 0.003
Values 0 0.0043
[143]
HepG2.C3A PRKACG
Mean 0
Standard deviation 0
Values 0 0
[144]
HuH.7 PRKACG
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[145]
SNU475 PRKACG
Mean 0
Standard deviation 0
Values 0 0
[146]
THLE PRKACG
Mean 0
Standard deviation 0
Values 0 0
[147]
liver PRKACG
Mean 0
Standard deviation 0
Values 0 0 0 0