REACTOME_CA_DEPENDENT_EVENTS | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | PRKAR1A | cAMP-dependent protein kinase type I-alpha regulatory subunit | [1] | -0.59[2] | -0.52[3] | -0.65[4] | -0.94[5] | -1.01[6] | -0.41[7] |
2 | KPNA2 | Importin subunit alpha-1 | [8] | 0.12[9] | -0.07[10] | 0.19[11] | -0.32[12] | 0.44[13] | -2.79[14] |
3 | CALM1 | Calmodulin-1 | [15] | -0.58[16] | -0.61[17] | -0.42[18] | 0.74[19] | 0.04[20] | 0.62[21] |
4 | PRKACA | cAMP-dependent protein kinase catalytic subunit alpha | [22] | -0.82[23] | -1.06[24] | -1.33[25] | -1.32[26] | -0.69[27] | -1.78[28] |
5 | MAPK1 | Mitogen-activated protein kinase 1 | [29] | 1.05[30] | 1.12[31] | 0.68[32] | 1.00[33] | 0.68[34] | 0.78[35] |
6 | CAMKK2 | Calcium/calmodulin-dependent protein kinase kinase 2 | [36] | -0.10[37] | 0.19[38] | -0.91[39] | -0.69[40] | -0.75[41] | -0.05[42] |
7 | PRKAR2A | cAMP-dependent protein kinase type II-alpha regulatory subunit | [43] | -0.61[44] | -0.99[45] | -0.15[46] | -1.13[47] | -1.24[48] | -0.85[49] |
8 | CAMK2D | Calcium/calmodulin-dependent protein kinase type II subunit delta | [50] | -0.53[51] | -0.28[52] | 0.97[53] | -0.17[54] | -0.95[55] | 0.41[56] |
9 | PRKAR1B | cAMP-dependent protein kinase type I-beta regulatory subunit | [57] | 0.31[58] | -0.30[59] | -2.36[60] | -4.94[61] | -2.12[62] | -1.17[63] |
10 | PRKCD | Protein kinase C delta type | [64] | 0.44[65] | 0.62[66] | -0.17[67] | -1.35[68] | -0.16[69] | -2.06[70] |
11 | CAMK2G | Calcium/calmodulin-dependent protein kinase type II subunit gamma | 0.11[71] | 1.26[72] | 0.61[73] | 0.84[74] | 0.43[75] | -0.04[76] | |
12 | PRKACB | cAMP-dependent protein kinase catalytic subunit beta | [77] | -1.49[78] | -0.78[79] | 0.23[80] | 1.39[81] | 0.28[82] | 0.71[83] |
13 | ADCY9 | Adenylate cyclase type 9 | [84] | 1.96[85] | 1.08[86] | 1.24[87] | 0.11[88] | -0.31[89] | 1.41[90] |
14 | PRKCA | Protein kinase C alpha type | [91] | 2.18[92] | 2.15[93] | 2.24[94] | 1.30[95] | 1.70[96] | 0.92[97] |
15 | ADCY6 | Adenylate cyclase type 6 | [98] | 1.39[99] | 1.79[100] | 1.48[101] | 1.66[102] | 2.36[103] | 1.64[104] |
16 | CREB1 | Cyclic AMP-responsive element-binding protein 1 | [105] | 1.06[106] | 2.15[107] | 2.37[108] | 1.70[109] | 1.67[110] | 1.35[111] |
17 | ADCY1 | Adenylate cyclase type 1 | [112] | -1.50[113] | -3.43[114] | -3.90[115] | -2.96[116] | -2.94[117] | 4.00[118] |
18 | PRKX | cAMP-dependent protein kinase catalytic subunit PRKX | [119] | -2.31[120] | -2.60[121] | 2.06[122] | 0.41[123] | 1.98[124] | 0.45[125] |
19 | CAMK2B | Calcium/calmodulin-dependent protein kinase type II subunit beta | [126] | -3.20[127] | -4.58[128] | -7.81[129] | -3.71[130] | -3.04[131] | 0.15[132] |
20 | ADCY7 | Adenylate cyclase type 7 | [133] | 2.85[134] | 2.41[135] | 1.10[136] | 2.46[137] | 1.97[138] | 1.93[139] |
21 | CAMKK1 | Calcium/calmodulin-dependent protein kinase kinase 1 | [140] | 0.59[141] | -0.18[142] | -2.15[143] | 2.00[144] | 0.48[145] | -0.91[146] |
22 | PRKAR2B | cAMP-dependent protein kinase type II-beta regulatory subunit | [147] | -3.00[148] | -1.24[149] | 2.77[150] | 4.24[151] | 2.79[152] | 2.32[153] |
23 | ADCY3 | Adenylate cyclase type 3 | [154] | 0.80[155] | -0.51[156] | 2.55[157] | 3.89[158] | 5.45[159] | 2.52[160] |
24 | ADCY2 | Adenylate cyclase type 2 | [161] | -6.04[162] | -4.17[163] | -5.70[164] | -3.58[165] | -4.67[166] | -5.12[167] |
25 | NBEA | Neurobeachin | [168] | 3.33[169] | 2.95[170] | 0.48[171] | 1.09[172] | 3.47[173] | 3.82[174] |
26 | PDE1B | Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | -4.34[175] | -5.38[176] | [177] | -1.66[178] | -2.71[179] | 2.87[180] | |
27 | ADCY5 | Adenylate cyclase type 5 | [181] | -0.51[182] | 0.43[183] | 1.19[184] | -0.20[185] | 0.96[186] | 5.38[187] |
28 | PRKCG | Protein kinase C gamma type | [188] | -1.48[189] | -0.87[190] | -3.52[191] | -1.91[192] | -1.97[193] | [194] |
29 | CAMK4 | Calcium/calmodulin-dependent protein kinase type IV | [195] | [196] | -2.49[197] | -3.42[198] | 0.60[199] | 2.70[200] | 3.25[201] |
30 | PLA2G4A | Cytosolic phospholipase A2 | [202] | -0.39[203] | -3.01[204] | 4.83[205] | 2.66[206] | 6.45[207] | 3.36[208] |
31 | PDE1A | Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A | [209] | -1.44[210] | 2.98[211] | 5.27[212] | 1.76[213] | 5.61[214] | |
32 | ADCY4 | Adenylate cyclase type 4 | [215] | -0.57[216] | -1.71[217] | 0.67[218] | [219] | [220] | 7.37[221] |
33 | GRK2 | Beta-adrenergic receptor kinase 1 | [222] | [223] | [224] | [225] | [226] | [227] | [228] |
34 | PRKACG | cAMP-dependent protein kinase catalytic subunit gamma | [229] | [230] | [231] | [232] | [233] | [234] | [235] |
35 | PDE1C | Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C | [236] | [237] | [238] | [239] | [240] | [241] | |
36 | ADCY8 | Adenylate cyclase type 8 | [242] | [243] | [244] | [245] | [246] | [247] | [248] |
37 | CAMK2A | Calcium/calmodulin-dependent protein kinase type II subunit alpha | [249] | [250] | [251] | [252] | [253] | [254] | [255] |