REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 VIM Vimentin [1] -9.01[2] -8.98[3] -3.12[4] 0.88[5] 0.75[6] -1.49[7]
2 GSN Gelsolin [8] 0.25[9] 0.47[10] -2.39[11] -3.13[12] -3.27[13] -2.16[14]
3 DBNL Drebrin-like protein [15] -1.11[16] -1.22[17] -1.34[18] -1.68[19] -1.44[20] -0.93[21]
4 ADD1 Alpha-adducin [22] 0.42[23] 0.01[24] 0.92[25] 0.28[26] -0.66[27] 0.35[28]
5 CASP3 Caspase-3 [29] -0.53[30] 0.62[31] -1.72[32] -2.61[33] -1.17[34] -1.05[35]
6 SPTAN1 Spectrin alpha chain, non-erythrocytic 1 [36] 2.08[37] 1.88[38] 2.77[39] 1.03[40] 1.62[41] 1.70[42]
7 CASP7 Caspase-7 [43] -0.97[44] -0.86[45] -0.22[46] -2.61[47] -1.96[48] -0.73[49]
8 CASP8 Caspase-8 [50] -0.64[51] 0.40[52] -0.22[53] -1.80[54] -2.10[55] -1.66[56]
9 CASP6 Caspase-6 [57] -1.93[58] -1.25[59] -0.68[60] -2.67[61] -2.55[62] -1.12[63]
10 PLEC Plectin [64] 2.73[65] 0.80[66] 2.41[67] 2.96[68] 3.05[69] 3.75[70]
11 GAS2 Growth arrest-specific protein 2 [71] -1.49[72] 1.91[73] 1.81[74] -7.11[75] -7.14[76] 2.01[77]
12 MAPT Microtubule-associated protein tau [78] 1.86[79] 2.28[80] 1.78[81] -0.38[82] -2.99[83] 0.09[84]
[1]
ref_hepatocyte VIM
Mean 54.6
Standard deviation 63
Values 0.056 1.2e+02 1.3e+02 12 14
[2]
HepG2 VIM
Mean 0.371
Standard deviation 0.34
Values 0.61 0.13
[3]
HepG2.C3A VIM
Mean 0.244
Standard deviation 0.11
Values 0.17 0.32
[4]
HuH.7 VIM
Mean 11.7
Standard deviation 9.3
Values 7.7 22 5.1
[5]
SNU475 VIM
Mean 609
Standard deviation 37
Values 6.4e+02 5.8e+02
[6]
THLE VIM
Mean 455
Standard deviation 1.6e+02
Values 3.4e+02 5.7e+02
[7]
liver VIM
Mean 32.8
Standard deviation 5.9
Values 37 35 35 24
[8]
ref_hepatocyte GSN
Mean 53.4
Standard deviation 97
Values 2.3e+02 15 3.1 18 4
[9]
HepG2 GSN
Mean 223
Standard deviation 3
Values 2.2e+02 2.2e+02
[10]
HepG2.C3A GSN
Mean 166
Standard deviation 59
Values 2.1e+02 1.2e+02
[11]
HuH.7 GSN
Mean 19
Standard deviation 14
Values 9.6 35 12
[12]
SNU475 GSN
Mean 36.8
Standard deviation 8.8
Values 43 31
[13]
THLE GSN
Mean 27.5
Standard deviation 4.2
Values 24 30
[14]
liver GSN
Mean 20.2
Standard deviation 4
Values 21 15 21 24
[15]
ref_hepatocyte DBNL
Mean 24.1
Standard deviation 16
Values 16 51 24 14 14
[16]
HepG2 DBNL
Mean 38.9
Standard deviation 2.5
Values 37 41
[17]
HepG2.C3A DBNL
Mean 23.2
Standard deviation 2.7
Values 21 25
[18]
HuH.7 DBNL
Mean 17.8
Standard deviation 5.7
Values 21 11 21
[19]
SNU475 DBNL
Mean 45.2
Standard deviation 7.3
Values 50 40
[20]
THLE DBNL
Mean 44.1
Standard deviation 5.4
Values 40 48
[21]
liver DBNL
Mean 21.3
Standard deviation 2
Values 23 19 23 20
[22]
ref_hepatocyte ADD1
Mean 18.5
Standard deviation 5.6
Values 26 21 21 13 13
[23]
HepG2 ADD1
Mean 86.6
Standard deviation 16
Values 76 98
[24]
HepG2.C3A ADD1
Mean 41.8
Standard deviation 1
Values 41 42
[25]
HuH.7 ADD1
Mean 65.4
Standard deviation 8.6
Values 71 55 69
[26]
SNU475 ADD1
Mean 136
Standard deviation 38
Values 1.6e+02 1.1e+02
[27]
THLE ADD1
Mean 57.9
Standard deviation 16
Values 47 69
[28]
liver ADD1
Mean 39.8
Standard deviation 6.5
Values 47 31 41 41
[29]
ref_hepatocyte CASP3
Mean 12.5
Standard deviation 12
Values 33 13 6.8 4.9 5.1
[30]
HepG2 CASP3
Mean 30.3
Standard deviation 8.2
Values 25 36
[31]
HepG2.C3A CASP3
Mean 43.1
Standard deviation 22
Values 27 59
[32]
HuH.7 CASP3
Mean 7.08
Standard deviation 1
Values 5.9 7.5 7.8
[33]
SNU475 CASP3
Mean 12.3
Standard deviation 0.36
Values 13 12
[34]
THLE CASP3
Mean 27.6
Standard deviation 0.68
Values 27 28
[35]
liver CASP3
Mean 10.2
Standard deviation 4.2
Values 9.5 9 16 6.1
[36]
ref_hepatocyte SPTAN1
Mean 12.4
Standard deviation 7.5
Values 14 24 9.8 8.3 5.1
[37]
HepG2 SPTAN1
Mean 184
Standard deviation 2.1
Values 1.8e+02 1.9e+02
[38]
HepG2.C3A SPTAN1
Mean 103
Standard deviation 10
Values 1.1e+02 96
[39]
HuH.7 SPTAN1
Mean 158
Standard deviation 56
Values 2.2e+02 1.2e+02 1.3e+02
[40]
SNU475 SPTAN1
Mean 153
Standard deviation 20
Values 1.7e+02 1.4e+02
[41]
THLE SPTAN1
Mean 189
Standard deviation 65
Values 1.4e+02 2.3e+02
[42]
liver SPTAN1
Mean 67.8
Standard deviation 40
Values 29 1.2e+02 42 84
[43]
ref_hepatocyte CASP7
Mean 10
Standard deviation 4.1
Values 7.8 14 15 7.6 6
[44]
HepG2 CASP7
Mean 17.9
Standard deviation 4
Values 15 21
[45]
HepG2.C3A CASP7
Mean 12.4
Standard deviation 4
Values 9.5 15
[46]
HuH.7 CASP7
Mean 16.1
Standard deviation 1.8
Values 15 15 18
[47]
SNU475 CASP7
Mean 9.89
Standard deviation 0.26
Values 10 9.7
[48]
THLE CASP7
Mean 12.8
Standard deviation 0.29
Values 13 13
[49]
liver CASP7
Mean 10.2
Standard deviation 3.1
Values 14 6.6 9.7 10
[50]
ref_hepatocyte CASP8
Mean 8.88
Standard deviation 6.8
Values 18 13 8.9 1.9 2.8
[51]
HepG2 CASP8
Mean 19.9
Standard deviation 3.1
Values 22 18
[52]
HepG2.C3A CASP8
Mean 26.3
Standard deviation 13
Values 17 35
[53]
HuH.7 CASP8
Mean 14.2
Standard deviation 3.6
Values 14 11 18
[54]
SNU475 CASP8
Mean 15.4
Standard deviation 0.7
Values 16 15
[55]
THLE CASP8
Mean 10.3
Standard deviation 0.97
Values 9.6 11
[56]
liver CASP8
Mean 4.72
Standard deviation 0.87
Values 3.4 5.2 5.3 5
[57]
ref_hepatocyte CASP6
Mean 8.44
Standard deviation 1.3
Values 8.6 10 7.9 7 8.2
[58]
HepG2 CASP6
Mean 7.74
Standard deviation 2.2
Values 6.2 9.3
[59]
HepG2.C3A CASP6
Mean 7.97
Standard deviation 4.4
Values 4.9 11
[60]
HuH.7 CASP6
Mean 9.83
Standard deviation 3.2
Values 10 6.4 13
[61]
SNU475 CASP6
Mean 8.02
Standard deviation 2.2
Values 9.5 6.5
[62]
THLE CASP6
Mean 7.17
Standard deviation 0.61
Values 6.7 7.6
[63]
liver CASP6
Mean 6.51
Standard deviation 3
Values 9.1 4 9.2 3.8
[64]
ref_hepatocyte PLEC
Mean 5.33
Standard deviation 4.2
Values 1.5 12 6.9 3 3.3
[65]
HepG2 PLEC
Mean 124
Standard deviation 52
Values 1.6e+02 87
[66]
HepG2.C3A PLEC
Mean 20.8
Standard deviation 1.4
Values 22 20
[67]
HuH.7 PLEC
Mean 53
Standard deviation 22
Values 77 47 35
[68]
SNU475 PLEC
Mean 251
Standard deviation 73
Values 3e+02 2e+02
[69]
THLE PLEC
Mean 219
Standard deviation 88
Values 1.6e+02 2.8e+02
[70]
liver PLEC
Mean 121
Standard deviation 85
Values 61 1.5e+02 45 2.3e+02
[71]
ref_hepatocyte GAS2
Mean 3.14
Standard deviation 2.4
Values 5.8 0.98 0.39 3.5 5
[72]
HepG2 GAS2
Mean 3.9
Standard deviation 0.64
Values 3.4 4.4
[73]
HepG2.C3A GAS2
Mean 26.6
Standard deviation 7.4
Values 21 32
[74]
HuH.7 GAS2
Mean 20.5
Standard deviation 3.5
Values 17 22 23
[75]
SNU475 GAS2
Mean 0.137
Standard deviation 0.029
Values 0.16 0.12
[76]
THLE GAS2
Mean 0.111
Standard deviation 0.036
Values 0.14 0.085
[77]
liver GAS2
Mean 21.4
Standard deviation 11
Values 37 18 18 12
[78]
ref_hepatocyte MAPT
Mean 0.398
Standard deviation 0.55
Values 1.3 0.29 0 0.29 0.057
[79]
HepG2 MAPT
Mean 5.07
Standard deviation 2.9
Values 7.1 3
[80]
HepG2.C3A MAPT
Mean 4.33
Standard deviation 2.4
Values 6 2.6
[81]
HuH.7 MAPT
Mean 2.56
Standard deviation 0.37
Values 2.8 2.8 2.1
[82]
SNU475 MAPT
Mean 1.84
Standard deviation 0.65
Values 1.4 2.3
[83]
THLE MAPT
Mean 0.248
Standard deviation 0.12
Values 0.33 0.16
[84]
liver MAPT
Mean 0.713
Standard deviation 0.37
Values 0.82 0.4 0.44 1.2