REACTOME_CASPASE_ACTIVATION_VIA_DEPENDENCE_RECEPTORS_IN_THE_ABSENCE_OF_LIGAND Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 MAGED1 Melanoma-associated antigen D1 [1] 0.75[2] 0.43[3] -7.10[4] 1.00[5] -0.20[6] -0.10[7]
2 DAPK3 Death-associated protein kinase 3 [8] -1.26[9] -1.56[10] -0.27[11] -1.64[12] -1.06[13] -2.86[14]
3 CASP3 Caspase-3 [15] -0.52[16] 0.07[17] -1.01[18] -1.77[19] -0.47[20] -1.10[21]
4 APPL1 DCC-interacting protein 13-alpha [22] -0.60[23] 0.50[24] 1.19[25] -0.11[26] 0.70[27] 1.50[28]
5 DAPK1 Death-associated protein kinase 1 [29] 0.43[30] 0.32[31] 2.76[32] -0.17[33] 0.29[34] 2.41[35]
6 CASP9 Caspase-9 [36] -0.49[37] 0.38[38] 0.96[39] -0.63[40] -1.00[41] -0.83[42]
7 DAPK2 Death-associated protein kinase 2 [43] -1.54[44] -2.98[45] 3.16[46] 0.39[47] -0.61[48] 0.73[49]
8 UNC5B Netrin receptor UNC5B [50] 1.73[51] -1.72[52] 2.28[53] 1.93[54] 6.55[55] 2.80[56]
9 UNC5A Netrin receptor UNC5A [57] 0.68[58] [59] 2.15[60] [61] 0.28[62] 4.06[63]
10 DCC Netrin receptor DCC [64] [65] [66] [67] [68] [69] [70]
[1]
ref_hepatocyte MAGED1
Mean 21.3
Standard deviation 12
Values 32 10 6.7 27 31
[2]
HepG2 MAGED1
Mean 125
Standard deviation 43
Values 94 1.6e+02
[3]
HepG2.C3A MAGED1
Mean 94.2
Standard deviation 35
Values 1.2e+02 69
[4]
HuH.7 MAGED1
Mean 0.177
Standard deviation 0.12
Values 0.24 0.26 0.037
[5]
SNU475 MAGED1
Mean 144
Standard deviation 64
Values 1.9e+02 98
[6]
THLE MAGED1
Mean 56.7
Standard deviation 14
Values 47 67
[7]
liver MAGED1
Mean 34.8
Standard deviation 20
Values 48 16 56 20
[8]
ref_hepatocyte DAPK3
Mean 16.8
Standard deviation 15
Values 6.2 30 36 6.4 5.3
[9]
HepG2 DAPK3
Mean 24.2
Standard deviation 4.9
Values 28 21
[10]
HepG2.C3A DAPK3
Mean 18.7
Standard deviation 8.3
Values 25 13
[11]
HuH.7 DAPK3
Mean 15.9
Standard deviation 1.3
Values 15 15 17
[12]
SNU475 DAPK3
Mean 18.1
Standard deviation 0.98
Values 19 17
[13]
THLE DAPK3
Mean 24.5
Standard deviation 3.4
Values 22 27
[14]
liver DAPK3
Mean 4.04
Standard deviation 1.6
Values 2.5 4.6 3 6
[15]
ref_hepatocyte CASP3
Mean 12.5
Standard deviation 12
Values 33 13 6.8 4.9 5.1
[16]
HepG2 CASP3
Mean 30.3
Standard deviation 8.2
Values 25 36
[17]
HepG2.C3A CASP3
Mean 43.1
Standard deviation 22
Values 27 59
[18]
HuH.7 CASP3
Mean 7.08
Standard deviation 1
Values 5.9 7.5 7.8
[19]
SNU475 CASP3
Mean 12.3
Standard deviation 0.36
Values 13 12
[20]
THLE CASP3
Mean 27.6
Standard deviation 0.68
Values 27 28
[21]
liver CASP3
Mean 10.2
Standard deviation 4.2
Values 9.5 9 16 6.1
[22]
ref_hepatocyte APPL1
Mean 4.53
Standard deviation 2.5
Values 5 8.5 4.2 1.9 3
[23]
HepG2 APPL1
Mean 10.4
Standard deviation 4.1
Values 7.5 13
[24]
HepG2.C3A APPL1
Mean 21
Standard deviation 2.9
Values 19 23
[25]
HuH.7 APPL1
Mean 11.8
Standard deviation 2
Values 13 13 9.5
[26]
SNU475 APPL1
Mean 14.2
Standard deviation 0.14
Values 14 14
[27]
THLE APPL1
Mean 22.4
Standard deviation 0.84
Values 23 22
[28]
liver APPL1
Mean 22.4
Standard deviation 5.5
Values 18 30 21 20
[29]
ref_hepatocyte DAPK1
Mean 3.31
Standard deviation 0.59
Values 3.2 3.3 4 2.4 3.7
[30]
HepG2 DAPK1
Mean 15.4
Standard deviation 5.3
Values 12 19
[31]
HepG2.C3A DAPK1
Mean 13.6
Standard deviation 0.21
Values 14 13
[32]
HuH.7 DAPK1
Mean 25.6
Standard deviation 6.1
Values 25 32 20
[33]
SNU475 DAPK1
Mean 9.91
Standard deviation 4.8
Values 13 6.5
[34]
THLE DAPK1
Mean 12.3
Standard deviation 2.9
Values 10 14
[35]
liver DAPK1
Mean 30.7
Standard deviation 5.3
Values 32 37 24 29
[36]
ref_hepatocyte CASP9
Mean 2.59
Standard deviation 1
Values 1.9 1.9 2 2.7 4.4
[37]
HepG2 CASP9
Mean 6.38
Standard deviation 0.81
Values 5.8 7
[38]
HepG2.C3A CASP9
Mean 11.1
Standard deviation 0.21
Values 11 11
[39]
HuH.7 CASP9
Mean 5.76
Standard deviation 1.5
Values 6.7 4.1 6.6
[40]
SNU475 CASP9
Mean 5.65
Standard deviation 0.92
Values 6.3 5
[41]
THLE CASP9
Mean 3.94
Standard deviation 0.43
Values 3.6 4.2
[42]
liver CASP9
Mean 2.54
Standard deviation 1.2
Values 2.4 1.9 4.2 1.6
[43]
ref_hepatocyte DAPK2
Mean 0.305
Standard deviation 0.2
Values 0.045 0.57 0.38 0.32 0.21
[44]
HepG2 DAPK2
Mean 0.362
Standard deviation 0.18
Values 0.49 0.23
[45]
HepG2.C3A DAPK2
Mean 0.127
Standard deviation 0.027
Values 0.15 0.11
[46]
HuH.7 DAPK2
Mean 3.1
Standard deviation 0.58
Values 2.4 3.5 3.4
[47]
SNU475 DAPK2
Mean 1.34
Standard deviation 0.16
Values 1.5 1.2
[48]
THLE DAPK2
Mean 0.606
Standard deviation 0.1
Values 0.68 0.53
[49]
liver DAPK2
Mean 0.885
Standard deviation 0.18
Values 1.1 0.88 0.69 0.83
[50]
ref_hepatocyte UNC5B
Mean 0.138
Standard deviation 0.21
Values 0 0 0.13 0.49 0.065
[51]
HepG2 UNC5B
Mean 1.58
Standard deviation 1.7
Values 2.8 0.39
[52]
HepG2.C3A UNC5B
Mean 0.137
Standard deviation 0.16
Values 0.25 0.021
[53]
HuH.7 UNC5B
Mean 0.761
Standard deviation 1.1
Values 0.13 2 0.13
[54]
SNU475 UNC5B
Mean 1.77
Standard deviation 0.05
Values 1.8 1.7
[55]
THLE UNC5B
Mean 39.2
Standard deviation 6.6
Values 44 35
[56]
liver UNC5B
Mean 1.67
Standard deviation 0.5
Values 1.8 1.8 0.98 2.2
[57]
ref_hepatocyte UNC5A
Mean 0.00862
Standard deviation 0.019
Values 0 0 0 0.043 0
[58]
HepG2 UNC5A
Mean 0.048
Standard deviation 0.038
Values 0.074 0.021
[59]
HepG2.C3A UNC5A
Mean 0
Standard deviation 0
Values 0 0
[60]
HuH.7 UNC5A
Mean 0.0435
Standard deviation 0.028
Values 0.074 0.019 0.037
[61]
SNU475 UNC5A
Mean 0
Standard deviation 0
Values 0 0
[62]
THLE UNC5A
Mean 0.0319
Standard deviation 0.045
Values 0 0.064
[63]
liver UNC5A
Mean 0.251
Standard deviation 0.22
Values 0.12 0.36 0.026 0.5
[64]
ref_hepatocyte DCC
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[65]
HepG2 DCC
Mean 0
Standard deviation 0
Values 0 0
[66]
HepG2.C3A DCC
Mean 0
Standard deviation 0
Values 0 0
[67]
HuH.7 DCC
Mean 0
Standard deviation 0
Values 0 0 0
[68]
SNU475 DCC
Mean 0.0228
Standard deviation 0.032
Values 0 0.046
[69]
THLE DCC
Mean 0
Standard deviation 0
Values 0 0
[70]
liver DCC
Mean 0.0171
Standard deviation 0.02
Values 0 0.029 0 0.04