REACTOME_CARGO_CONCENTRATION_IN_THE_ER | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | SERPINA1 | Alpha-1-antitrypsin | [1] | -0.60[2] | -0.46[3] | -1.06[4] | -8.78[5] | -7.46[6] | -0.06[7] |
2 | TMED2 | Transmembrane emp24 domain-containing protein 2 | [8] | 1.28[9] | 1.58[10] | 1.38[11] | 2.77[12] | 2.59[13] | 0.05[14] |
3 | LMAN2 | Vesicular integral-membrane protein VIP36 | [15] | 0.55[16] | -0.05[17] | 1.16[18] | 1.25[19] | 1.49[20] | -0.76[21] |
4 | CTSZ | Cathepsin Z | [22] | -8.14[23] | -8.29[24] | -0.33[25] | 1.56[26] | 1.39[27] | -2.67[28] |
5 | SEC22B | Vesicle-trafficking protein SEC22b | [29] | 0.66[30] | 0.27[31] | 1.10[32] | 3.17[33] | 3.56[34] | -0.70[35] |
6 | LMAN1 | Protein ERGIC-53 | [36] | 1.99[37] | 2.59[38] | 3.54[39] | 3.87[40] | 4.23[41] | 1.47[42] |
7 | MCFD2 | Multiple coagulation factor deficiency protein 2 | [43] | 3.28[44] | 3.53[45] | 2.89[46] | 4.44[47] | 4.60[48] | 1.13[49] |
8 | TMED10 | Transmembrane emp24 domain-containing protein 10 | [50] | 2.59[51] | 2.51[52] | 3.18[53] | 4.21[54] | 4.40[55] | 1.24[56] |
9 | SEC23A | Protein transport protein Sec23A | [57] | 4.11[58] | 2.37[59] | 4.36[60] | 4.76[61] | 3.90[62] | 0.78[63] |
10 | CD59 | CD59 glycoprotein | [64] | 3.23[65] | 2.09[66] | 1.44[67] | 4.31[68] | 5.06[69] | 0.79[70] |
11 | PREB | Prolactin regulatory element-binding protein | [71] | 2.35[72] | 2.45[73] | 2.14[74] | 2.89[75] | 2.73[76] | -0.09[77] |
12 | F5 | Coagulation factor V | [78] | 2.92[79] | 3.06[80] | 4.90[81] | -2.23[82] | -2.19[83] | 3.19[84] |
13 | GOSR2 | Golgi SNAP receptor complex member 2 | [85] | 2.65[86] | 2.15[87] | 2.01[88] | 4.10[89] | 3.45[90] | 0.28[91] |
14 | CTSC | Dipeptidyl peptidase 1 | [92] | 4.58[93] | 3.65[94] | 4.91[95] | 4.31[96] | 5.04[97] | -0.57[98] |
15 | STX5 | Syntaxin-5 | [99] | 1.61[100] | 1.46[101] | 2.46[102] | 2.94[103] | 3.15[104] | -0.97[105] |
16 | SEC24C | Protein transport protein Sec24C | [106] | 3.69[107] | 3.56[108] | 3.81[109] | 5.47[110] | 4.84[111] | 1.03[112] |
17 | SAR1B | GTP-binding protein SAR1b | [113] | 1.92[114] | 2.61[115] | 3.40[116] | 3.84[117] | 4.15[118] | 2.58[119] |
18 | SEC24D | Protein transport protein Sec24D | [120] | 2.51[121] | 2.81[122] | 3.73[123] | 4.82[124] | 4.40[125] | 1.55[126] |
19 | LMAN2L | VIP36-like protein | [127] | 2.79[128] | 1.95[129] | 2.99[130] | 3.31[131] | 3.70[132] | -1.17[133] |
20 | MIA3 | Transport and Golgi organization protein 1 homolog | [134] | 1.66[135] | 1.94[136] | 4.28[137] | 5.16[138] | 4.30[139] | 1.93[140] |
21 | SEC24A | Protein transport protein Sec24A | [141] | 3.38[142] | 3.37[143] | 4.93[144] | 5.43[145] | 4.56[146] | 2.13[147] |
22 | SEC24B | Protein transport protein Sec24B | [148] | 2.36[149] | 2.17[150] | 3.20[151] | 4.30[152] | 4.75[153] | 1.81[154] |
23 | AREG | Amphiregulin | [155] | -0.68[156] | -4.45[157] | -5.27[158] | -5.86[159] | 4.33[160] | -10.58[161] |
24 | MIA2 | Melanoma inhibitory activity protein 2 | [162] | -0.24[163] | 1.22[164] | 3.79[165] | 1.11[166] | -3.15[167] | 1.91[168] |
25 | TGFA | Protransforming growth factor alpha | [169] | 3.97[170] | 4.51[171] | -5.60[172] | 2.88[173] | 1.54[174] | -0.67[175] |
26 | F8 | Coagulation factor VIII | [176] | -0.57[177] | -0.91[178] | 0.35[179] | 2.30[180] | 2.01[181] | 3.45[182] |
27 | COL7A1 | Collagen alpha-1(VII) chain | [183] | 5.06[184] | 7.51[185] | 5.49[186] | 9.63[187] | 8.47[188] | 0.00[189] |
28 | FOLR1 | Folate receptor alpha | [190] | 4.35[191] | -1.67[192] | 1.78[193] | 8.18[194] | -1.18[195] | -0.92[196] |
29 | CNIH2 | Protein cornichon homolog 2 | [197] | 4.11[198] | 4.70[199] | 5.68[200] | 6.58[201] | 6.23[202] | -1.03[203] |
30 | CNIH3 | Protein cornichon homolog 3 | [204] | 1.84[205] | 0.51[206] | 3.95[207] | 6.97[208] | 6.46[209] | -0.08[210] |
31 | GRIA1 | Glutamate receptor 1 | [211] | -0.15[212] | [213] | [214] | 3.19[215] | 3.51[216] | -0.14[217] |
32 | LMAN1L | Protein ERGIC-53-like | [218] | [219] | [220] | [221] | [222] | [223] | [224] |
33 | CNIH1 | Protein cornichon homolog 1 | [225] | [226] | [227] | [228] | [229] | [230] | [231] |