REACTOME_BUTYRATE_RESPONSE_FACTOR_1_BRF1_BINDS_AND_DESTABILIZES_MRNA Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 YWHAB 14-3-3 protein beta/alpha [1] 1.05[2] 0.79[3] 0.26[4] 1.10[5] 0.69[6] -0.02[7]
2 ZFP36L1 mRNA decay activator protein ZFP36L1 [8] -1.06[9] -2.08[10] -1.55[11] -0.37[12] -0.68[13] 0.33[14]
3 AKT1 RAC-alpha serine/threonine-protein kinase [15] 0.09[16] -0.11[17] -1.00[18] -0.25[19] -0.08[20] -0.16[21]
4 EXOSC4 Exosome complex component RRP41 [22] -1.51[23] -1.12[24] -1.56[25] -2.04[26] -2.57[27] -1.59[28]
5 EXOSC7 Exosome complex component RRP42 [29] -1.35[30] -1.33[31] -0.57[32] -2.91[33] -1.81[34] -1.77[35]
6 EXOSC3 Exosome complex component RRP40 [36] -1.10[37] -1.17[38] -0.26[39] -2.13[40] -1.32[41] -1.73[42]
7 MAPKAPK2 MAP kinase-activated protein kinase 2 [43] 0.47[44] -0.47[45] 0.14[46] 1.20[47] 0.55[48] -0.86[49]
8 EXOSC9 Exosome complex component RRP45 [50] -1.32[51] -0.85[52] -1.19[53] -1.64[54] 0.19[55] -2.05[56]
9 EXOSC5 Exosome complex component RRP46 [57] -0.93[58] -0.87[59] 0.39[60] -2.11[61] -1.53[62] -0.98[63]
10 EXOSC2 Exosome complex component RRP4 [64] 0.24[65] 0.10[66] 0.61[67] -0.53[68] 0.57[69] -0.61[70]
11 EXOSC1 Exosome complex component CSL4 [71] -0.08[72] 0.63[73] 1.12[74] -1.10[75] -0.03[76] -0.88[77]
12 EXOSC6 Exosome complex component MTR3 [78] -0.21[79] -0.15[80] -1.19[81] -1.25[82] -0.51[83] -0.55[84]
13 EXOSC8 Exosome complex component RRP43 [85] 0.16[86] 1.01[87] 1.40[88] -0.93[89] 0.27[90] -0.58[91]
14 DIS3 Exosome complex exonuclease RRP44 [92] 0.91[93] 1.96[94] 2.83[95] 1.60[96] 1.79[97] 2.04[98]
15 DCP1A mRNA-decapping enzyme 1A [99] 1.83[100] 2.24[101] 1.86[102] 1.19[103] 2.21[104] 2.84[105]
16 DCP2 m7GpppN-mRNA hydrolase [106] 1.80[107] 3.55[108] 2.90[109] 2.24[110] 2.27[111] 3.28[112]
17 XRN1 5'-3' exoribonuclease 1 [113] 0.85[114] 2.40[115] 2.98[116] 2.75[117] 2.76[118] 4.58[119]
[1]
ref_hepatocyte YWHAB
Mean 42.6
Standard deviation 20
Values 74 47 41 28 22
[2]
HepG2 YWHAB
Mean 193
Standard deviation 37
Values 1.7e+02 2.2e+02
[3]
HepG2.C3A YWHAB
Mean 141
Standard deviation 27
Values 1.2e+02 1.6e+02
[4]
HuH.7 YWHAB
Mean 82.2
Standard deviation 26
Values 98 52 97
[5]
SNU475 YWHAB
Mean 193
Standard deviation 7
Values 2e+02 1.9e+02
[6]
THLE YWHAB
Mean 146
Standard deviation 23
Values 1.3e+02 1.6e+02
[7]
liver YWHAB
Mean 56.6
Standard deviation 26
Values 78 39 80 30
[8]
ref_hepatocyte ZFP36L1
Mean 40.1
Standard deviation 16
Values 16 55 54 37 39
[9]
HepG2 ZFP36L1
Mean 42.1
Standard deviation 5.8
Values 46 38
[10]
HepG2.C3A ZFP36L1
Mean 18.2
Standard deviation 0.12
Values 18 18
[11]
HuH.7 ZFP36L1
Mean 22.1
Standard deviation 6.1
Values 27 15 24
[12]
SNU475 ZFP36L1
Mean 65.4
Standard deviation 2.4
Values 67 64
[13]
THLE ZFP36L1
Mean 53.5
Standard deviation 2.5
Values 52 55
[14]
liver ZFP36L1
Mean 67.8
Standard deviation 71
Values 1.5e+02 12 95 9.2
[15]
ref_hepatocyte AKT1
Mean 37.6
Standard deviation 15
Values 55 50 19 31 32
[16]
HepG2 AKT1
Mean 87.8
Standard deviation 2.3
Values 89 86
[17]
HepG2.C3A AKT1
Mean 66.6
Standard deviation 2.4
Values 65 68
[18]
HuH.7 AKT1
Mean 30.2
Standard deviation 6.6
Values 33 23 35
[19]
SNU475 AKT1
Mean 66.6
Standard deviation 14
Values 76 57
[20]
THLE AKT1
Mean 75.8
Standard deviation 6.1
Values 72 80
[21]
liver AKT1
Mean 45.1
Standard deviation 25
Values 34 48 20 79
[22]
ref_hepatocyte EXOSC4
Mean 20
Standard deviation 9.6
Values 7.2 18 34 23 18
[23]
HepG2 EXOSC4
Mean 15.4
Standard deviation 1
Values 16 15
[24]
HepG2.C3A EXOSC4
Mean 17.7
Standard deviation 0.81
Values 18 17
[25]
HuH.7 EXOSC4
Mean 10.9
Standard deviation 5
Values 12 5.5 15
[26]
SNU475 EXOSC4
Mean 10.2
Standard deviation 1.9
Values 8.9 12
[27]
THLE EXOSC4
Mean 7.19
Standard deviation 1.1
Values 6.4 8
[28]
liver EXOSC4
Mean 8.91
Standard deviation 7.7
Values 18 2.2 13 2.8
[29]
ref_hepatocyte EXOSC7
Mean 19.5
Standard deviation 5.3
Values 20 25 24 15 13
[30]
HepG2 EXOSC7
Mean 16.8
Standard deviation 1.4
Values 18 16
[31]
HepG2.C3A EXOSC7
Mean 14.8
Standard deviation 0.76
Values 15 14
[32]
HuH.7 EXOSC7
Mean 21.1
Standard deviation 7.8
Values 22 13 28
[33]
SNU475 EXOSC7
Mean 5.45
Standard deviation 0.71
Values 6 4.9
[34]
THLE EXOSC7
Mean 11.8
Standard deviation 0.76
Values 11 12
[35]
liver EXOSC7
Mean 7.69
Standard deviation 4.4
Values 12 4.5 11 3.4
[36]
ref_hepatocyte EXOSC3
Mean 15.3
Standard deviation 11
Values 24 29 9.4 7.1 6.5
[37]
HepG2 EXOSC3
Mean 15.6
Standard deviation 2
Values 14 17
[38]
HepG2.C3A EXOSC3
Mean 13
Standard deviation 5
Values 9.5 17
[39]
HuH.7 EXOSC3
Mean 20.5
Standard deviation 9.1
Values 23 10 28
[40]
SNU475 EXOSC3
Mean 7.33
Standard deviation 0.48
Values 7 7.7
[41]
THLE EXOSC3
Mean 13
Standard deviation 1.4
Values 12 14
[42]
liver EXOSC3
Mean 6.17
Standard deviation 1.8
Values 7.1 4.7 8.3 4.6
[43]
ref_hepatocyte MAPKAPK2
Mean 13.1
Standard deviation 7.6
Values 5.2 10 24 17 8.7
[44]
HepG2 MAPKAPK2
Mean 39.7
Standard deviation 1.4
Values 41 39
[45]
HepG2.C3A MAPKAPK2
Mean 18.1
Standard deviation 4.5
Values 21 15
[46]
HuH.7 MAPKAPK2
Mean 23.2
Standard deviation 2.9
Values 25 20 25
[47]
SNU475 MAPKAPK2
Mean 63.2
Standard deviation 4
Values 66 60
[48]
THLE MAPKAPK2
Mean 40.9
Standard deviation 0.33
Values 41 41
[49]
liver MAPKAPK2
Mean 9.67
Standard deviation 2.5
Values 10 11 6 11
[50]
ref_hepatocyte EXOSC9
Mean 11.8
Standard deviation 9.9
Values 17 27 6.1 4.9 4
[51]
HepG2 EXOSC9
Mean 10.3
Standard deviation 2.7
Values 8.4 12
[52]
HepG2.C3A EXOSC9
Mean 12.5
Standard deviation 4.3
Values 9.4 16
[53]
HuH.7 EXOSC9
Mean 8.29
Standard deviation 1.6
Values 8.5 6.6 9.8
[54]
SNU475 EXOSC9
Mean 7.97
Standard deviation 2
Values 6.6 9.4
[55]
THLE EXOSC9
Mean 28.7
Standard deviation 1
Values 29 28
[56]
liver EXOSC9
Mean 3.81
Standard deviation 1.1
Values 5.2 3.3 4.1 2.7
[57]
ref_hepatocyte EXOSC5
Mean 10.7
Standard deviation 6.4
Values 3.4 5.9 17 18 9.8
[58]
HepG2 EXOSC5
Mean 12.3
Standard deviation 4.6
Values 16 9.1
[59]
HepG2.C3A EXOSC5
Mean 11.2
Standard deviation 0.51
Values 11 12
[60]
HuH.7 EXOSC5
Mean 22.5
Standard deviation 11
Values 26 9.8 31
[61]
SNU475 EXOSC5
Mean 5.21
Standard deviation 1.6
Values 4 6.4
[62]
THLE EXOSC5
Mean 7.89
Standard deviation 0.98
Values 7.2 8.6
[63]
liver EXOSC5
Mean 7.26
Standard deviation 6.1
Values 13 2.2 12 1.8
[64]
ref_hepatocyte EXOSC2
Mean 7.07
Standard deviation 2.8
Values 6.3 12 7.1 6.6 3.7
[65]
HepG2 EXOSC2
Mean 18.3
Standard deviation 0.66
Values 18 19
[66]
HepG2.C3A EXOSC2
Mean 14.5
Standard deviation 5.8
Values 10 19
[67]
HuH.7 EXOSC2
Mean 17.3
Standard deviation 8.4
Values 20 7.8 24
[68]
SNU475 EXOSC2
Mean 10.3
Standard deviation 1.6
Values 9.2 11
[69]
THLE EXOSC2
Mean 22.3
Standard deviation 6.3
Values 18 27
[70]
liver EXOSC2
Mean 6.22
Standard deviation 0.73
Values 5.8 6.9 6.7 5.4
[71]
ref_hepatocyte EXOSC1
Mean 6.86
Standard deviation 3.7
Values 3.9 5 4 12 9
[72]
HepG2 EXOSC1
Mean 14.2
Standard deviation 0.4
Values 15 14
[73]
HepG2.C3A EXOSC1
Mean 20.3
Standard deviation 1.4
Values 19 21
[74]
HuH.7 EXOSC1
Mean 24
Standard deviation 5.1
Values 23 19 29
[75]
SNU475 EXOSC1
Mean 6.72
Standard deviation 0.24
Values 6.9 6.5
[76]
THLE EXOSC1
Mean 14.3
Standard deviation 0.39
Values 15 14
[77]
liver EXOSC1
Mean 5.02
Standard deviation 3.7
Values 8.6 2 7.9 1.6
[78]
ref_hepatocyte EXOSC6
Mean 6.69
Standard deviation 5
Values 15 5.3 4 3.2 5.5
[79]
HepG2 EXOSC6
Mean 12.7
Standard deviation 0.74
Values 13 12
[80]
HepG2.C3A EXOSC6
Mean 11.5
Standard deviation 1.3
Values 11 12
[81]
HuH.7 EXOSC6
Mean 4.71
Standard deviation 1.3
Values 4.4 3.6 6.2
[82]
SNU475 EXOSC6
Mean 5.93
Standard deviation 0.11
Values 5.9 6
[83]
THLE EXOSC6
Mean 9.98
Standard deviation 1.4
Values 9 11
[84]
liver EXOSC6
Mean 6.12
Standard deviation 2.8
Values 3.1 7.5 4.5 9.4
[85]
ref_hepatocyte EXOSC8
Mean 5.67
Standard deviation 0.99
Values 4.8 5.8 4.7 7.1 5.9
[86]
HepG2 EXOSC8
Mean 13.9
Standard deviation 2.4
Values 12 16
[87]
HepG2.C3A EXOSC8
Mean 21.9
Standard deviation 7.8
Values 16 27
[88]
HuH.7 EXOSC8
Mean 24
Standard deviation 11
Values 24 13 35
[89]
SNU475 EXOSC8
Mean 6.25
Standard deviation 0.33
Values 6 6.5
[90]
THLE EXOSC8
Mean 14.5
Standard deviation 0.013
Values 15 15
[91]
liver EXOSC8
Mean 5.08
Standard deviation 4
Values 8.7 1.9 8.3 1.4
[92]
ref_hepatocyte DIS3
Mean 3.36
Standard deviation 0.85
Values 3.9 3.2 4.6 2.8 2.4
[93]
HepG2 DIS3
Mean 13.9
Standard deviation 5.1
Values 10 17
[94]
HepG2.C3A DIS3
Mean 25.1
Standard deviation 4.1
Values 22 28
[95]
HuH.7 DIS3
Mean 38.4
Standard deviation 2.7
Values 42 37 36
[96]
SNU475 DIS3
Mean 21.4
Standard deviation 0.63
Values 21 22
[97]
THLE DIS3
Mean 24.8
Standard deviation 1.5
Values 26 24
[98]
liver DIS3
Mean 18.5
Standard deviation 4.7
Values 16 25 15 19
[99]
ref_hepatocyte DCP1A
Mean 1.83
Standard deviation 1.1
Values 3.5 1.5 2.5 0.84 0.81
[100]
HepG2 DCP1A
Mean 14.3
Standard deviation 0.89
Values 15 14
[101]
HepG2.C3A DCP1A
Mean 16.6
Standard deviation 4.4
Values 20 13
[102]
HuH.7 DCP1A
Mean 10.7
Standard deviation 2.4
Values 11 13 8.3
[103]
SNU475 DCP1A
Mean 8.77
Standard deviation 0.21
Values 8.9 8.6
[104]
THLE DCP1A
Mean 18.1
Standard deviation 0.25
Values 18 18
[105]
liver DCP1A
Mean 17.6
Standard deviation 11
Values 27 8.2 27 8.4
[106]
ref_hepatocyte DCP2
Mean 1.54
Standard deviation 1.2
Values 3.4 2.2 0.65 0.48 1
[107]
HepG2 DCP2
Mean 11.8
Standard deviation 4.5
Values 8.6 15
[108]
HepG2.C3A DCP2
Mean 34.5
Standard deviation 0.73
Values 34 35
[109]
HuH.7 DCP2
Mean 18.4
Standard deviation 1.8
Values 21 17 18
[110]
SNU475 DCP2
Mean 15.3
Standard deviation 1.8
Values 17 14
[111]
THLE DCP2
Mean 15.9
Standard deviation 2.3
Values 17 14
[112]
liver DCP2
Mean 20.1
Standard deviation 9
Values 10 31 15 24
[113]
ref_hepatocyte XRN1
Mean 1.16
Standard deviation 0.38
Values 1.2 0.93 0.77 1.1 1.8
[114]
HepG2 XRN1
Mean 4.6
Standard deviation 2.1
Values 3.1 6.1
[115]
HepG2.C3A XRN1
Mean 11.7
Standard deviation 1.4
Values 13 11
[116]
HuH.7 XRN1
Mean 14.7
Standard deviation 7.6
Values 13 23 7.7
[117]
SNU475 XRN1
Mean 16.4
Standard deviation 4
Values 19 14
[118]
THLE XRN1
Mean 16.8
Standard deviation 3.5
Values 19 14
[119]
liver XRN1
Mean 37.2
Standard deviation 15
Values 32 51 19 47