REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 YAP1 Transcriptional coactivator YAP1 [1] 0.28[2] -0.03[3] -0.37[4] 0.00[5] -0.32[6] -1.70[7]
2 WWTR1 WW domain-containing transcription regulator protein 1 [8] 0.21[9] 0.02[10] -0.94[11] 0.03[12] -0.39[13] -1.31[14]
3 HIPK2 Homeodomain-interacting protein kinase 2 [15] 0.31[16] 0.86[17] 0.23[18] 0.44[19] 0.82[20] 2.39[21]
4 GATA4 Transcription factor GATA-4 [22] -0.90[23] -0.73[24] 0.72[25] -3.50[26] -0.30[27] -1.46[28]
5 HIPK1 Homeodomain-interacting protein kinase 1 [29] -0.11[30] 0.14[31] 1.11[32] -0.08[33] 0.05[34] 0.20[35]
6 KAT2B Histone acetyltransferase KAT2B [36] -3.73[37] -4.62[38] -2.23[39] -2.35[40] -1.66[41] -0.26[42]
7 TEAD2 Transcriptional enhancer factor TEF-4 [43] -0.64[44] -1.47[45] 0.10[46] -0.27[47] -1.15[48] -2.46[49]
8 TEAD4 Transcriptional enhancer factor TEF-3 [50] 0.60[51] 0.24[52] -0.70[53] -2.65[54] -2.07[55] -4.58[56]
9 TEAD3 Transcriptional enhancer factor TEF-5 [57] 0.18[58] 0.44[59] -1.18[60] -1.29[61] -1.00[62] -2.22[63]
10 TEAD1 Transcriptional enhancer factor TEF-1 [64] 0.05[65] 0.61[66] 0.94[67] 2.19[68] 1.38[69] 1.18[70]
11 NKX2-5 Homeobox protein Nkx-2.5 [71] 0.37[72] -1.92[73] -7.98[74] -6.13[75] 3.22[76] [77]
12 NPPA Natriuretic peptides A [78] -2.24[79] 3.01[80] -0.99[81] -2.00[82] -2.87[83] -2.67[84]
13 TBX5 T-box transcription factor TBX5 [85] [86] [87] [88] -5.46[89] [90] [91]
14 RUNX2 Runt-related transcription factor 2 [92] -2.53[93] -2.66[94] 2.44[95] 4.84[96] 7.07[97] 1.57[98]
15 CCN2 [99] [100] [101] [102] [103] [104] [105]
[1]
ref_hepatocyte YAP1
Mean 11.1
Standard deviation 8.2
Values 25 11 7.6 4.3 7.3
[2]
HepG2 YAP1
Mean 95.6
Standard deviation 11
Values 88 1e+02
[3]
HepG2.C3A YAP1
Mean 58.4
Standard deviation 12
Values 50 67
[4]
HuH.7 YAP1
Mean 43.3
Standard deviation 5.4
Values 49 44 38
[5]
SNU475 YAP1
Mean 99
Standard deviation 6.2
Values 1e+02 95
[6]
THLE YAP1
Mean 73.9
Standard deviation 11
Values 66 81
[7]
liver YAP1
Mean 20.1
Standard deviation 14
Values 9.5 26 7.2 38
[8]
ref_hepatocyte WWTR1
Mean 5.02
Standard deviation 4.3
Values 12 3.8 5.4 1.2 2.6
[9]
HepG2 WWTR1
Mean 41.2
Standard deviation 0.072
Values 41 41
[10]
HepG2.C3A WWTR1
Mean 27.5
Standard deviation 7.8
Values 33 22
[11]
HuH.7 WWTR1
Mean 13.3
Standard deviation 1.5
Values 13 15 12
[12]
SNU475 WWTR1
Mean 45.7
Standard deviation 8.3
Values 52 40
[13]
THLE WWTR1
Mean 31.8
Standard deviation 6
Values 28 36
[14]
liver WWTR1
Mean 11.9
Standard deviation 2.9
Values 14 11 15 8.4
[15]
ref_hepatocyte HIPK2
Mean 4.12
Standard deviation 1.9
Values 6.3 5.4 4.4 1.7 2.8
[16]
HepG2 HIPK2
Mean 36.3
Standard deviation 11
Values 29 44
[17]
HepG2.C3A HIPK2
Mean 40.4
Standard deviation 2.3
Values 42 39
[18]
HuH.7 HIPK2
Mean 24.6
Standard deviation 9.8
Values 32 29 13
[19]
SNU475 HIPK2
Mean 50.1
Standard deviation 7.4
Values 55 45
[20]
THLE HIPK2
Mean 60.5
Standard deviation 7.6
Values 55 66
[21]
liver HIPK2
Mean 127
Standard deviation 19
Values 1.1e+02 1.3e+02 1.1e+02 1.5e+02
[22]
ref_hepatocyte GATA4
Mean 3.97
Standard deviation 2.3
Values 6.3 1 2.3 6 4.3
[23]
HepG2 GATA4
Mean 15.1
Standard deviation 1.5
Values 14 16
[24]
HepG2.C3A GATA4
Mean 12.9
Standard deviation 0.72
Values 13 12
[25]
HuH.7 GATA4
Mean 33.3
Standard deviation 6.5
Values 30 41 29
[26]
SNU475 GATA4
Mean 3.13
Standard deviation 0.12
Values 3.2 3
[27]
THLE GATA4
Mean 26.9
Standard deviation 1.1
Values 26 28
[28]
liver GATA4
Mean 8.47
Standard deviation 2.5
Values 12 6.8 9.2 6.2
[29]
ref_hepatocyte HIPK1
Mean 3.63
Standard deviation 1.7
Values 5.5 3.9 5 1.6 2.2
[30]
HepG2 HIPK1
Mean 23.8
Standard deviation 5.7
Values 20 28
[31]
HepG2.C3A HIPK1
Mean 21.6
Standard deviation 1.5
Values 21 23
[32]
HuH.7 HIPK1
Mean 39.7
Standard deviation 13
Values 46 48 25
[33]
SNU475 HIPK1
Mean 30.8
Standard deviation 0.34
Values 31 31
[34]
THLE HIPK1
Mean 31.2
Standard deviation 4.2
Values 28 34
[35]
liver HIPK1
Mean 24.5
Standard deviation 7.7
Values 20 31 16 31
[36]
ref_hepatocyte KAT2B
Mean 3.02
Standard deviation 2.4
Values 0.53 4.6 0.74 3.2 6.1
[37]
HepG2 KAT2B
Mean 1.62
Standard deviation 1.1
Values 0.84 2.4
[38]
HepG2.C3A KAT2B
Mean 0.662
Standard deviation 0.012
Values 0.67 0.65
[39]
HuH.7 KAT2B
Mean 3.28
Standard deviation 0.41
Values 2.8 3.6 3.4
[40]
SNU475 KAT2B
Mean 5.31
Standard deviation 1.3
Values 6.2 4.4
[41]
THLE KAT2B
Mean 7.98
Standard deviation 1.1
Values 7.2 8.8
[42]
liver KAT2B
Mean 14.8
Standard deviation 5
Values 19 17 7.6 16
[43]
ref_hepatocyte TEAD2
Mean 2.96
Standard deviation 1
Values 1.9 3.8 3.4 3.9 1.7
[44]
HepG2 TEAD2
Mean 13.5
Standard deviation 1.1
Values 14 13
[45]
HepG2.C3A TEAD2
Mean 5.75
Standard deviation 0.31
Values 5.5 6
[46]
HuH.7 TEAD2
Mean 16
Standard deviation 5.2
Values 19 10 19
[47]
SNU475 TEAD2
Mean 21.9
Standard deviation 0.61
Values 22 21
[48]
THLE TEAD2
Mean 11.1
Standard deviation 0.75
Values 11 12
[49]
liver TEAD2
Mean 3.18
Standard deviation 0.45
Values 3.6 2.8 2.8 3.6
[50]
ref_hepatocyte TEAD4
Mean 2.75
Standard deviation 2.6
Values 1.7 0.71 4.7 6.2 0.39
[51]
HepG2 TEAD4
Mean 29.5
Standard deviation 5.2
Values 33 26
[52]
HepG2.C3A TEAD4
Mean 17.5
Standard deviation 1.2
Values 18 17
[53]
HuH.7 TEAD4
Mean 8.56
Standard deviation 1.9
Values 10 6.6 8.7
[54]
SNU475 TEAD4
Mean 3.92
Standard deviation 0.34
Values 3.7 4.2
[55]
THLE TEAD4
Mean 5.43
Standard deviation 1.1
Values 4.6 6.2
[56]
liver TEAD4
Mean 0.678
Standard deviation 0.23
Values 0.45 0.66 1 0.61
[57]
ref_hepatocyte TEAD3
Mean 2.73
Standard deviation 1.6
Values 3 0.74 4.5 3.8 1.6
[58]
HepG2 TEAD3
Mean 22
Standard deviation 1.9
Values 21 23
[59]
HepG2.C3A TEAD3
Mean 19.9
Standard deviation 1.9
Values 21 19
[60]
HuH.7 TEAD3
Mean 6.12
Standard deviation 0.37
Values 6.5 5.8 6
[61]
SNU475 TEAD3
Mean 9.97
Standard deviation 0.35
Values 10 9.7
[62]
THLE TEAD3
Mean 11.4
Standard deviation 0.69
Values 11 12
[63]
liver TEAD3
Mean 3.46
Standard deviation 0.81
Values 4.3 2.3 3.5 3.8
[64]
ref_hepatocyte TEAD1
Mean 2.43
Standard deviation 1.7
Values 1.9 3.7 4.6 0.79 1.2
[65]
HepG2 TEAD1
Mean 17.8
Standard deviation 6.4
Values 13 22
[66]
HepG2.C3A TEAD1
Mean 19.9
Standard deviation 0.76
Values 20 19
[67]
HuH.7 TEAD1
Mean 23.7
Standard deviation 6.1
Values 28 27 17
[68]
SNU475 TEAD1
Mean 99
Standard deviation 4.2
Values 1e+02 96
[69]
THLE TEAD1
Mean 52.7
Standard deviation 4.7
Values 49 56
[70]
liver TEAD1
Mean 32.3
Standard deviation 8.2
Values 31 41 22 36
[71]
ref_hepatocyte NKX2-5
Mean 0.136
Standard deviation 0.28
Values 0.64 0 0 0 0.041
[72]
HepG2 NKX2-5
Mean 1.24
Standard deviation 0.63
Values 1.7 0.8
[73]
HepG2.C3A NKX2-5
Mean 0.193
Standard deviation 0.12
Values 0.11 0.28
[74]
HuH.7 NKX2-5
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[75]
SNU475 NKX2-5
Mean 0.0173
Standard deviation 0.011
Values 0.0093 0.025
[76]
THLE NKX2-5
Mean 10.5
Standard deviation 1.6
Values 9.4 12
[77]
liver NKX2-5
Mean 0
Standard deviation 0
Values 0 0 0 0
[78]
ref_hepatocyte NPPA
Mean 0.0328
Standard deviation 0.073
Values 0 0 0 0.16 0
[79]
HepG2 NPPA
Mean 0.0494
Standard deviation 0.021
Values 0.034 0.064
[80]
HepG2.C3A NPPA
Mean 1.42
Standard deviation 0.87
Values 2 0.8
[81]
HuH.7 NPPA
Mean 0.0837
Standard deviation 0.043
Values 0.049 0.071 0.13
[82]
SNU475 NPPA
Mean 0.0732
Standard deviation 0.018
Values 0.06 0.086
[83]
THLE NPPA
Mean 0.0373
Standard deviation 0.023
Values 0.053 0.021
[84]
liver NPPA
Mean 0.0304
Standard deviation 0.043
Values 0.094 0.014 0 0.013
[85]
ref_hepatocyte TBX5
Mean 0.0228
Standard deviation 0.036
Values 0.033 0 0 0 0.081
[86]
HepG2 TBX5
Mean 0
Standard deviation 0
Values 0 0
[87]
HepG2.C3A TBX5
Mean 0
Standard deviation 0
Values 0 0
[88]
HuH.7 TBX5
Mean 0
Standard deviation 0
Values 0 0 0
[89]
SNU475 TBX5
Mean 0.00464
Standard deviation 0.0066
Values 0.0093 0
[90]
THLE TBX5
Mean 0
Standard deviation 0
Values 0 0
[91]
liver TBX5
Mean 0
Standard deviation 0
Values 0 0 0 0
[92]
ref_hepatocyte RUNX2
Mean 0.0228
Standard deviation 0.051
Values 0 0 0 0 0.11
[93]
HepG2 RUNX2
Mean 0.0279
Standard deviation 0.033
Values 0.052 0.0043
[94]
HepG2.C3A RUNX2
Mean 0.0194
Standard deviation 0.027
Values 0.039 0
[95]
HuH.7 RUNX2
Mean 0.624
Standard deviation 0.22
Values 0.54 0.87 0.46
[96]
SNU475 RUNX2
Mean 5.82
Standard deviation 3.1
Values 3.6 8
[97]
THLE RUNX2
Mean 25.4
Standard deviation 0.45
Values 26 25
[98]
liver RUNX2
Mean 0.398
Standard deviation 0.22
Values 0.71 0.29 0.21 0.4
[99]
ref_hepatocyte CCN2
Missing
[100]
HepG2 CCN2
Missing
[101]
HepG2.C3A CCN2
Missing
[102]
HuH.7 CCN2
Missing
[103]
SNU475 CCN2
Missing
[104]
THLE CCN2
Missing
[105]
liver CCN2
Missing