REACTOME_WNT_LIGAND_BIOGENESIS_AND_TRAFFICKING Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 SNX3 Sorting nexin-3 [1] -1.00[2] -1.68[3] -1.17[4] -1.36[5] -1.75[6] -1.20[7]
2 VPS29 Vacuolar protein sorting-associated protein 29 [8] -1.02[9] -0.80[10] -0.98[11] -1.36[12] -1.71[13] -0.63[14]
3 VPS35 Vacuolar protein sorting-associated protein 35 [15] 1.67[16] 1.14[17] 1.02[18] 0.97[19] 0.20[20] -0.11[21]
4 TMED5 Transmembrane emp24 domain-containing protein 5 [22] 1.13[23] 2.23[24] 2.17[25] 0.90[26] 0.26[27] 2.52[28]
5 VPS26A Vacuolar protein sorting-associated protein 26A [29] 0.22[30] 0.66[31] 0.08[32] 0.73[33] 0.28[34] -0.34[35]
6 WNT11 Protein Wnt-11 [36] -0.60[37] -7.00[38] -5.34[39] -6.37[40] -7.21[41] -2.77[42]
7 WLS Protein wntless homolog [43] -5.78[44] -10.68[45] -4.80[46] 1.50[47] 2.89[48] -0.34[49]
8 WNT3 Proto-oncogene Wnt-3 [50] 0.43[51] 0.70[52] -0.59[53] -0.41[54] -2.16[55] 0.49[56]
9 WNT5B Protein Wnt-5b [57] -4.12[58] -5.98[59] 1.21[60] 1.73[61] -2.49[62] -0.89[63]
10 PORCN Protein-serine O-palmitoleoyltransferase porcupine [64] 2.74[65] 0.53[66] 2.24[67] 2.51[68] 3.06[69] 0.84[70]
11 WNT4 Protein Wnt-4 [71] -2.87[72] -2.70[73] -3.17[74] -1.20[75] -2.94[76] 0.53[77]
12 WNT5A Protein Wnt-5a [78] -2.37[79] -3.05[80] -1.25[81] 6.75[82] 7.91[83] 1.63[84]
13 WNT7B Protein Wnt-7b [85] 3.51[86] 1.00[87] 1.39[88] 0.49[89] -0.87[90] -0.51[91]
14 WNT9B Protein Wnt-9b [92] -3.23[93] -4.74[94] -0.55[95] [96] [97] -4.54[98]
15 WNT9A Protein Wnt-9a [99] 0.87[100] -2.94[101] -3.09[102] 1.39[103] -1.23[104] -2.32[105]
16 WNT2B Protein Wnt-2b [106] 0.19[107] 0.28[108] 0.90[109] 2.76[110] 1.66[111] 1.24[112]
17 WNT16 Protein Wnt-16 [113] [114] [115] [116] 1.50[117] -2.78[118] 0.47[119]
18 WNT10A Protein Wnt-10a [120] 2.07[121] -1.96[122] -4.03[123] 3.70[124] -2.48[125] -1.17[126]
19 WNT2 Protein Wnt-2 [127] [128] [129] -1.24[130] 1.09[131] -3.26[132] 6.53[133]
20 WNT1 Proto-oncogene Wnt-1 [134] [135] [136] [137] [138] [139] [140]
21 WNT8A Protein Wnt-8a [141] [142] [143] [144] [145] [146] [147]
22 WNT3A Protein Wnt-3a [148] [149] [150] [151] [152] [153] [154]
23 WNT6 Protein Wnt-6 [155] [156] [157] [158] [159] [160] [161]
24 WNT7A Protein Wnt-7a [162] [163] [164] [165] [166] [167] [168]
25 WNT8B Protein Wnt-8b [169] [170] [171] [172] [173] [174] [175]
26 WNT10B Protein Wnt-10b [176] [177] [178] [179] [180] [181] [182]
[1]
ref_hepatocyte SNX3
Mean 101
Standard deviation 45
Values 70 1.8e+02 67 1.1e+02 86
[2]
HepG2 SNX3
Mean 63.5
Standard deviation 12
Values 55 72
[3]
HepG2.C3A SNX3
Mean 56.8
Standard deviation 8.5
Values 51 63
[4]
HuH.7 SNX3
Mean 50.1
Standard deviation 7.9
Values 41 56 53
[5]
SNU475 SNX3
Mean 65.2
Standard deviation 13
Values 74 56
[6]
THLE SNX3
Mean 73.9
Standard deviation 6.9
Values 69 79
[7]
liver SNX3
Mean 50.6
Standard deviation 30
Values 69 31 82 19
[8]
ref_hepatocyte VPS29
Mean 38
Standard deviation 6.9
Values 37 43 29 35 46
[9]
HepG2 VPS29
Mean 23.5
Standard deviation 2.4
Values 22 25
[10]
HepG2.C3A VPS29
Mean 39.1
Standard deviation 13
Values 30 48
[11]
HuH.7 VPS29
Mean 21.4
Standard deviation 7.9
Values 23 13 29
[12]
SNU475 VPS29
Mean 24.4
Standard deviation 6.3
Values 29 20
[13]
THLE VPS29
Mean 28.6
Standard deviation 2.7
Values 27 31
[14]
liver VPS29
Mean 28.1
Standard deviation 27
Values 60 6.6 41 4.9
[15]
ref_hepatocyte VPS35
Mean 22.4
Standard deviation 20
Values 56 26 13 6.9 9.2
[16]
HepG2 VPS35
Mean 89.1
Standard deviation 21
Values 74 1e+02
[17]
HepG2.C3A VPS35
Mean 88.3
Standard deviation 25
Values 71 1.1e+02
[18]
HuH.7 VPS35
Mean 50.5
Standard deviation 3.7
Values 53 53 46
[19]
SNU475 VPS35
Mean 72.2
Standard deviation 18
Values 85 59
[20]
THLE VPS35
Mean 63.1
Standard deviation 6.3
Values 59 68
[21]
liver VPS35
Mean 23.7
Standard deviation 5.8
Values 26 25 28 15
[22]
ref_hepatocyte TMED5
Mean 17.2
Standard deviation 4.7
Values 21 16 9.7 21 18
[23]
HepG2 TMED5
Mean 47.1
Standard deviation 19
Values 34 61
[24]
HepG2.C3A TMED5
Mean 145
Standard deviation 29
Values 1.2e+02 1.7e+02
[25]
HuH.7 TMED5
Mean 85.8
Standard deviation 16
Values 84 1e+02 70
[26]
SNU475 TMED5
Mean 52.7
Standard deviation 7.5
Values 58 47
[27]
THLE TMED5
Mean 50.5
Standard deviation 0.062
Values 51 50
[28]
liver TMED5
Mean 113
Standard deviation 17
Values 1.1e+02 1.1e+02 1.3e+02 94
[29]
ref_hepatocyte VPS26A
Mean 15.4
Standard deviation 11
Values 29 26 8.5 6.9 7
[30]
HepG2 VPS26A
Mean 22.4
Standard deviation 4.9
Values 19 26
[31]
HepG2.C3A VPS26A
Mean 43.6
Standard deviation 11
Values 36 51
[32]
HuH.7 VPS26A
Mean 18.1
Standard deviation 1.5
Values 19 16 19
[33]
SNU475 VPS26A
Mean 42.1
Standard deviation 1.9
Values 43 41
[34]
THLE VPS26A
Mean 46
Standard deviation 0.29
Values 46 46
[35]
liver VPS26A
Mean 13.9
Standard deviation 7.3
Values 20 8 20 7.2
[36]
ref_hepatocyte WNT11
Mean 8.08
Standard deviation 18
Values 40 0.06 0.11 0.37 0.25
[37]
HepG2 WNT11
Mean 6.66
Standard deviation 4.3
Values 9.7 3.6
[38]
HepG2.C3A WNT11
Mean 0.113
Standard deviation 0.037
Values 0.087 0.14
[39]
HuH.7 WNT11
Mean 0.221
Standard deviation 0.18
Values 0.13 0.43 0.1
[40]
SNU475 WNT11
Mean 0.16
Standard deviation 0.017
Values 0.15 0.17
[41]
THLE WNT11
Mean 0.134
Standard deviation 0.054
Values 0.17 0.096
[42]
liver WNT11
Mean 1.35
Standard deviation 0.38
Values 1.2 1.1 1.2 1.9
[43]
ref_hepatocyte WLS
Mean 4.89
Standard deviation 4.1
Values 0 11 2.8 4.9 5.7
[44]
HepG2 WLS
Mean 0.112
Standard deviation 0.037
Values 0.14 0.086
[45]
HepG2.C3A WLS
Mean 0.00536
Standard deviation 0.0076
Values 0 0.011
[46]
HuH.7 WLS
Mean 0.194
Standard deviation 0.088
Values 0.16 0.3 0.13
[47]
SNU475 WLS
Mean 22.7
Standard deviation 0.42
Values 22 23
[48]
THLE WLS
Mean 88.7
Standard deviation 18
Values 76 1e+02
[49]
liver WLS
Mean 4.41
Standard deviation 0.76
Values 3.4 5.2 4.5 4.6
[50]
ref_hepatocyte WNT3
Mean 0.906
Standard deviation 0.51
Values 1.2 0.39 1.2 1.4 0.33
[51]
HepG2 WNT3
Mean 1.53
Standard deviation 0.052
Values 1.6 1.5
[52]
HepG2.C3A WNT3
Mean 2.64
Standard deviation 0.37
Values 2.4 2.9
[53]
HuH.7 WNT3
Mean 0.668
Standard deviation 0.15
Values 0.69 0.81 0.51
[54]
SNU475 WNT3
Mean 1.12
Standard deviation 0.23
Values 1.3 0.96
[55]
THLE WNT3
Mean 0.498
Standard deviation 0.085
Values 0.44 0.56
[56]
liver WNT3
Mean 1.46
Standard deviation 0.82
Values 0.78 1.8 0.8 2.5
[57]
ref_hepatocyte WNT5B
Mean 0.735
Standard deviation 0.91
Values 0 0.48 0.095 0.84 2.3
[58]
HepG2 WNT5B
Mean 0.053
Standard deviation 0.01
Values 0.046 0.06
[59]
HepG2.C3A WNT5B
Mean 0.0209
Standard deviation 0.016
Values 0.0097 0.032
[60]
HuH.7 WNT5B
Mean 1.89
Standard deviation 2.2
Values 0.63 4.4 0.62
[61]
SNU475 WNT5B
Mean 4.02
Standard deviation 1.6
Values 5.1 2.9
[62]
THLE WNT5B
Mean 0.321
Standard deviation 0.035
Values 0.3 0.35
[63]
liver WNT5B
Mean 0.453
Standard deviation 0.26
Values 0.73 0.26 0.62 0.21
[64]
ref_hepatocyte PORCN
Mean 0.515
Standard deviation 0.54
Values 0.13 0 0.6 1.4 0.46
[65]
HepG2 PORCN
Mean 4.3
Standard deviation 0.89
Values 4.9 3.7
[66]
HepG2.C3A PORCN
Mean 1.33
Standard deviation 0.037
Values 1.4 1.3
[67]
HuH.7 PORCN
Mean 2.7
Standard deviation 0.3
Values 2.4 2.9 2.8
[68]
SNU475 PORCN
Mean 4.84
Standard deviation 2.2
Values 3.3 6.4
[69]
THLE PORCN
Mean 10.6
Standard deviation 0.24
Values 11 10
[70]
liver PORCN
Mean 1.05
Standard deviation 0.4
Values 1.3 0.64 1.5 0.79
[71]
ref_hepatocyte WNT4
Mean 0.276
Standard deviation 0.47
Values 0 0 0.3 1.1 0
[72]
HepG2 WNT4
Mean 0.0472
Standard deviation 0.0061
Values 0.052 0.043
[73]
HepG2.C3A WNT4
Mean 0.0764
Standard deviation 0.0019
Values 0.078 0.075
[74]
HuH.7 WNT4
Mean 0.034
Standard deviation 0.022
Values 0.033 0.013 0.056
[75]
SNU475 WNT4
Mean 0.197
Standard deviation 0.1
Values 0.13 0.27
[76]
THLE WNT4
Mean 0.0881
Standard deviation 0.034
Values 0.11 0.064
[77]
liver WNT4
Mean 0.454
Standard deviation 0.67
Values 0.024 0.3 0.051 1.4
[78]
ref_hepatocyte WNT5A
Mean 0.261
Standard deviation 0.17
Values 0 0.4 0.23 0.25 0.43
[79]
HepG2 WNT5A
Mean 0.063
Standard deviation 0.041
Values 0.092 0.034
[80]
HepG2.C3A WNT5A
Mean 0.0565
Standard deviation 0.011
Values 0.049 0.064
[81]
HuH.7 WNT5A
Mean 0.122
Standard deviation 0.062
Values 0.18 0.13 0.056
[82]
SNU475 WNT5A
Mean 46.2
Standard deviation 6.6
Values 51 42
[83]
THLE WNT5A
Mean 154
Standard deviation 20
Values 1.7e+02 1.4e+02
[84]
liver WNT5A
Mean 0.919
Standard deviation 0.41
Values 0.54 1.3 0.59 1.2
[85]
ref_hepatocyte WNT7B
Mean 0.175
Standard deviation 0.091
Values 0.26 0.11 0.049 0.22 0.24
[86]
HepG2 WNT7B
Mean 2.49
Standard deviation 0.78
Values 3 1.9
[87]
HepG2.C3A WNT7B
Mean 0.629
Standard deviation 0.1
Values 0.7 0.56
[88]
HuH.7 WNT7B
Mean 0.507
Standard deviation 0.054
Values 0.56 0.51 0.45
[89]
SNU475 WNT7B
Mean 0.403
Standard deviation 0.12
Values 0.32 0.49
[90]
THLE WNT7B
Mean 0.235
Standard deviation 0.014
Values 0.22 0.24
[91]
liver WNT7B
Mean 0.14
Standard deviation 0.14
Values 0.024 0.29 0.026 0.23
[92]
ref_hepatocyte WNT9B
Mean 0.145
Standard deviation 0.2
Values 0 0.4 0.32 0 0
[93]
HepG2 WNT9B
Mean 0.0193
Standard deviation 0.021
Values 0.034 0.0043
[94]
HepG2.C3A WNT9B
Mean 0.00972
Standard deviation 0.014
Values 0.019 0
[95]
HuH.7 WNT9B
Mean 0.11
Standard deviation 0.043
Values 0.11 0.064 0.15
[96]
SNU475 WNT9B
Mean 0
Standard deviation 0
Values 0 0
[97]
THLE WNT9B
Mean 0
Standard deviation 0
Values 0 0
[98]
liver WNT9B
Mean 0.00713
Standard deviation 0.014
Values 0 0.029 0 0
[99]
ref_hepatocyte WNT9A
Mean 0.115
Standard deviation 0.17
Values 0 0.19 0.38 0 0
[100]
HepG2 WNT9A
Mean 0.263
Standard deviation 0.0014
Values 0.26 0.26
[101]
HepG2.C3A WNT9A
Mean 0.0268
Standard deviation 0.038
Values 0 0.054
[102]
HuH.7 WNT9A
Mean 0.015
Standard deviation 0.026
Values 0 0.045 0
[103]
SNU475 WNT9A
Mean 0.497
Standard deviation 0.065
Values 0.54 0.45
[104]
THLE WNT9A
Mean 0.12
Standard deviation 0.0028
Values 0.12 0.12
[105]
liver WNT9A
Mean 0.0264
Standard deviation 0.036
Values 0 0.029 0.077 0
[106]
ref_hepatocyte WNT2B
Mean 0.0592
Standard deviation 0.13
Values 0 0 0.3 0 0
[107]
HepG2 WNT2B
Mean 0.0845
Standard deviation 0.059
Values 0.13 0.043
[108]
HepG2.C3A WNT2B
Mean 0.129
Standard deviation 0.092
Values 0.19 0.064
[109]
HuH.7 WNT2B
Mean 0.123
Standard deviation 0.076
Values 0.12 0.2 0.047
[110]
SNU475 WNT2B
Mean 0.66
Standard deviation 0.36
Values 0.91 0.41
[111]
THLE WNT2B
Mean 0.461
Standard deviation 0.19
Values 0.59 0.33
[112]
liver WNT2B
Mean 0.16
Standard deviation 0.13
Values 0.14 0.14 0.026 0.33
[113]
ref_hepatocyte WNT16
Mean 0.0473
Standard deviation 0.11
Values 0 0 0.24 0 0
[114]
HepG2 WNT16
Mean 0
Standard deviation 0
Values 0 0
[115]
HepG2.C3A WNT16
Mean 0
Standard deviation 0
Values 0 0
[116]
HuH.7 WNT16
Mean 0
Standard deviation 0
Values 0 0 0
[117]
SNU475 WNT16
Mean 0.22
Standard deviation 0.01
Values 0.23 0.21
[118]
THLE WNT16
Mean 0.0169
Standard deviation 0.0013
Values 0.018 0.016
[119]
liver WNT16
Mean 0.0746
Standard deviation 0.073
Values 0.024 0.14 0 0.13
[120]
ref_hepatocyte WNT10A
Mean 0.0316
Standard deviation 0.045
Values 0 0 0 0.06 0.098
[121]
HepG2 WNT10A
Mean 0.166
Standard deviation 0.065
Values 0.21 0.12
[122]
HepG2.C3A WNT10A
Mean 0.0146
Standard deviation 0.021
Values 0.029 0
[123]
HuH.7 WNT10A
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[124]
SNU475 WNT10A
Mean 0.677
Standard deviation 0.49
Values 1 0.33
[125]
THLE WNT10A
Mean 0.0139
Standard deviation 0.0029
Values 0.012 0.016
[126]
liver WNT10A
Mean 0.0161
Standard deviation 0.012
Values 0.024 0.014 0 0.026
[127]
ref_hepatocyte WNT2
Mean 0.0103
Standard deviation 0.023
Values 0 0 0 0.052 0
[128]
HepG2 WNT2
Mean 0
Standard deviation 0
Values 0 0
[129]
HepG2.C3A WNT2
Mean 0
Standard deviation 0
Values 0 0
[130]
HuH.7 WNT2
Mean 0.00487
Standard deviation 0.0043
Values 0.0082 0.0064 0
[131]
SNU475 WNT2
Mean 0.0363
Standard deviation 0.0011
Values 0.037 0.035
[132]
THLE WNT2
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[133]
liver WNT2
Mean 1.1
Standard deviation 0.37
Values 1.6 0.76 1.2 0.87
[134]
ref_hepatocyte WNT1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[135]
HepG2 WNT1
Mean 0.043
Standard deviation 0.036
Values 0.069 0.017
[136]
HepG2.C3A WNT1
Mean 0
Standard deviation 0
Values 0 0
[137]
HuH.7 WNT1
Mean 0.37
Standard deviation 0.12
Values 0.41 0.23 0.47
[138]
SNU475 WNT1
Mean 0.00464
Standard deviation 0.0066
Values 0.0093 0
[139]
THLE WNT1
Mean 0
Standard deviation 0
Values 0 0
[140]
liver WNT1
Mean 0.0351
Standard deviation 0.032
Values 0.024 0 0.077 0.04
[141]
ref_hepatocyte WNT8A
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[142]
HepG2 WNT8A
Missing
[143]
HepG2.C3A WNT8A
Missing
[144]
HuH.7 WNT8A
Missing
[145]
SNU475 WNT8A
Missing
[146]
THLE WNT8A
Missing
[147]
liver WNT8A
Missing
[148]
ref_hepatocyte WNT3A
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[149]
HepG2 WNT3A
Mean 0.0093
Standard deviation 0.005
Values 0.0057 0.013
[150]
HepG2.C3A WNT3A
Mean 0
Standard deviation 0
Values 0 0
[151]
HuH.7 WNT3A
Mean 0
Standard deviation 0
Values 0 0 0
[152]
SNU475 WNT3A
Mean 0.00485
Standard deviation 0.0003
Values 0.0046 0.0051
[153]
THLE WNT3A
Mean 0.00266
Standard deviation 0.0038
Values 0 0.0053
[154]
liver WNT3A
Mean 0.0165
Standard deviation 0.033
Values 0 0 0 0.066
[155]
ref_hepatocyte WNT6
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[156]
HepG2 WNT6
Mean 1.58
Standard deviation 0.17
Values 1.7 1.5
[157]
HepG2.C3A WNT6
Mean 0
Standard deviation 0
Values 0 0
[158]
HuH.7 WNT6
Mean 0.00915
Standard deviation 0.0097
Values 0.0082 0.019 0
[159]
SNU475 WNT6
Mean 7.36
Standard deviation 4.5
Values 11 4.2
[160]
THLE WNT6
Mean 0.0328
Standard deviation 0.021
Values 0.018 0.048
[161]
liver WNT6
Mean 0.0284
Standard deviation 0.034
Values 0.024 0 0.077 0.013
[162]
ref_hepatocyte WNT7A
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[163]
HepG2 WNT7A
Missing
[164]
HepG2.C3A WNT7A
Missing
[165]
HuH.7 WNT7A
Missing
[166]
SNU475 WNT7A
Missing
[167]
THLE WNT7A
Missing
[168]
liver WNT7A
Missing
[169]
ref_hepatocyte WNT8B
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[170]
HepG2 WNT8B
Mean 0.058
Standard deviation 0.064
Values 0.1 0.013
[171]
HepG2.C3A WNT8B
Mean 0.0979
Standard deviation 0.028
Values 0.078 0.12
[172]
HuH.7 WNT8B
Mean 0.46
Standard deviation 0.11
Values 0.56 0.33 0.49
[173]
SNU475 WNT8B
Mean 0
Standard deviation 0
Values 0 0
[174]
THLE WNT8B
Mean 0.0163
Standard deviation 0.015
Values 0.0059 0.027
[175]
liver WNT8B
Mean 0.0477
Standard deviation 0.042
Values 0 0.086 0.026 0.079
[176]
ref_hepatocyte WNT10B
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[177]
HepG2 WNT10B
Mean 0.815
Standard deviation 0.33
Values 0.58 1.1
[178]
HepG2.C3A WNT10B
Mean 0.0608
Standard deviation 0.01
Values 0.068 0.054
[179]
HuH.7 WNT10B
Mean 0.527
Standard deviation 0.25
Values 0.47 0.31 0.81
[180]
SNU475 WNT10B
Mean 0.827
Standard deviation 0.49
Values 0.48 1.2
[181]
THLE WNT10B
Mean 0.296
Standard deviation 0.025
Values 0.28 0.31
[182]
liver WNT10B
Mean 0.0403
Standard deviation 0.039
Values 0 0.043 0.026 0.093