REACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD4 Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CLTA Clathrin light chain A [1] -2.08[2] -1.99[3] -2.30[4] -2.63[5] -2.61[6] -3.24[7]
2 CLTB Clathrin light chain B [8] -0.77[9] -2.50[10] -3.11[11] -2.82[12] -2.81[13] -2.27[14]
3 AP2M1 AP-2 complex subunit mu [15] 0.02[16] 0.09[17] -0.83[18] 0.81[19] 0.97[20] -0.14[21]
4 AP2S1 AP-2 complex subunit sigma [22] -1.82[23] -1.57[24] -1.29[25] -0.91[26] -0.83[27] -1.00[28]
5 CLTC Clathrin heavy chain 1 [29] 1.42[30] 1.78[31] 1.54[32] 1.51[33] 1.30[34] 2.48[35]
6 AP2A1 AP-2 complex subunit alpha-1 [36] 1.01[37] 0.94[38] 1.35[39] 1.23[40] 0.95[41] 0.98[42]
7 AP2B1 AP-2 complex subunit beta [43] 2.04[44] 2.04[45] 3.34[46] 2.38[47] 1.89[48] 0.96[49]
8 AP2A2 AP-2 complex subunit alpha-2 [50] 1.06[51] 1.17[52] 0.88[53] 0.67[54] -0.03[55] 0.70[56]
9 ARRB2 Beta-arrestin-2 [57] -0.03[58] 0.62[59] 0.16[60] -1.49[61] -1.03[62] -0.85[63]
10 FZD4 Frizzled-4 [64] 3.89[65] 3.09[66] 1.71[67] 0.52[68] -0.50[69] 2.97[70]
11 PRKCA Protein kinase C alpha type [71] 2.64[72] 2.95[73] 2.89[74] 1.98[75] 1.99[76] 1.94[77]
12 DVL2 Segment polarity protein dishevelled homolog DVL-2 [78] 1.92[79] 1.94[80] 2.50[81] 2.05[82] 1.35[83] 0.04[84]
13 WNT5A Protein Wnt-5a [85] -3.39[86] -3.11[87] -2.37[88] 6.42[89] 7.65[90] 1.34[91]
14 PRKCB Protein kinase C beta type [92] -7.01[93] -5.55[94] [95] 2.31[96] -3.34[97] 3.56[98]
15 PRKCG Protein kinase C gamma type [99] -1.02[100] -0.08[101] -2.88[102] -1.23[103] -1.67[104] [105]
[1]
ref_hepatocyte CLTA
Mean 139
Standard deviation 77
Values 2e+02 2.3e+02 1.4e+02 74 53
[2]
HepG2 CLTA
Mean 83.5
Standard deviation 9.9
Values 91 77
[3]
HepG2.C3A CLTA
Mean 65.7
Standard deviation 0.97
Values 66 65
[4]
HuH.7 CLTA
Mean 68.1
Standard deviation 8
Values 60 68 76
[5]
SNU475 CLTA
Mean 46.3
Standard deviation 2.6
Values 48 45
[6]
THLE CLTA
Mean 67.1
Standard deviation 17
Values 55 79
[7]
liver CLTA
Mean 20.5
Standard deviation 13
Values 32 10 31 8.4
[8]
ref_hepatocyte CLTB
Mean 49.9
Standard deviation 29
Values 19 72 89 39 30
[9]
HepG2 CLTB
Mean 74.4
Standard deviation 33
Values 98 51
[10]
HepG2.C3A CLTB
Mean 16.5
Standard deviation 2.8
Values 15 18
[11]
HuH.7 CLTB
Mean 13.9
Standard deviation 2.8
Values 14 11 17
[12]
SNU475 CLTB
Mean 14.6
Standard deviation 1.2
Values 14 15
[13]
THLE CLTB
Mean 21
Standard deviation 2.5
Values 19 23
[14]
liver CLTB
Mean 14.4
Standard deviation 8.2
Values 24 8.6 19 6.4
[15]
ref_hepatocyte AP2M1
Mean 41.6
Standard deviation 13
Values 28 39 35 63 44
[16]
HepG2 AP2M1
Mean 107
Standard deviation 14
Values 97 1.2e+02
[17]
HepG2.C3A AP2M1
Mean 83
Standard deviation 17
Values 71 95
[18]
HuH.7 AP2M1
Mean 56.4
Standard deviation 14
Values 67 40 62
[19]
SNU475 AP2M1
Mean 150
Standard deviation 32
Values 1.7e+02 1.3e+02
[20]
THLE AP2M1
Mean 241
Standard deviation 26
Values 2.2e+02 2.6e+02
[21]
liver AP2M1
Mean 52.8
Standard deviation 26
Values 55 35 89 32
[22]
ref_hepatocyte AP2S1
Mean 38.3
Standard deviation 23
Values 13 36 20 57 66
[23]
HepG2 AP2S1
Mean 27.5
Standard deviation 0.19
Values 28 27
[24]
HepG2.C3A AP2S1
Mean 24.1
Standard deviation 3.4
Values 22 27
[25]
HuH.7 AP2S1
Mean 37.6
Standard deviation 15
Values 43 21 49
[26]
SNU475 AP2S1
Mean 42
Standard deviation 3.1
Values 44 40
[27]
THLE AP2S1
Mean 63.5
Standard deviation 6.7
Values 59 68
[28]
liver AP2S1
Mean 26.7
Standard deviation 27
Values 53 3.8 46 3.4
[29]
ref_hepatocyte CLTC
Mean 30
Standard deviation 17
Values 53 42 13 19 24
[30]
HepG2 CLTC
Mean 203
Standard deviation 93
Values 1.4e+02 2.7e+02
[31]
HepG2.C3A CLTC
Mean 193
Standard deviation 28
Values 1.7e+02 2.1e+02
[32]
HuH.7 CLTC
Mean 209
Standard deviation 37
Values 2.5e+02 2.1e+02 1.7e+02
[33]
SNU475 CLTC
Mean 176
Standard deviation 18
Values 1.9e+02 1.6e+02
[34]
THLE CLTC
Mean 218
Standard deviation 18
Values 2.1e+02 2.3e+02
[35]
liver CLTC
Mean 234
Standard deviation 1.1e+02
Values 1.2e+02 3.7e+02 1.8e+02 2.7e+02
[36]
ref_hepatocyte AP2A1
Mean 10.6
Standard deviation 3.7
Values 6.9 8.6 9.7 17 11
[37]
HepG2 AP2A1
Mean 54
Standard deviation 4.5
Values 57 51
[38]
HepG2.C3A AP2A1
Mean 38.1
Standard deviation 9.3
Values 45 32
[39]
HuH.7 AP2A1
Mean 65.1
Standard deviation 18
Values 85 50 60
[40]
SNU475 AP2A1
Mean 51.3
Standard deviation 9.3
Values 58 45
[41]
THLE AP2A1
Mean 60.6
Standard deviation 7.6
Values 55 66
[42]
liver AP2A1
Mean 29.1
Standard deviation 3.1
Values 28 27 27 34
[43]
ref_hepatocyte AP2B1
Mean 9
Standard deviation 4.1
Values 11 15 5.6 5.9 7.2
[44]
HepG2 AP2B1
Mean 93.9
Standard deviation 10
Values 87 1e+02
[45]
HepG2.C3A AP2B1
Mean 69.3
Standard deviation 14
Values 79 59
[46]
HuH.7 AP2B1
Mean 220
Standard deviation 43
Values 2.7e+02 2e+02 1.9e+02
[47]
SNU475 AP2B1
Mean 96.9
Standard deviation 32
Values 1.2e+02 74
[48]
THLE AP2B1
Mean 98.4
Standard deviation 18
Values 86 1.1e+02
[49]
liver AP2B1
Mean 24.4
Standard deviation 6.6
Values 18 34 23 23
[50]
ref_hepatocyte AP2A2
Mean 8.24
Standard deviation 1.1
Values 7.8 6.8 8.3 9.9 8.3
[51]
HepG2 AP2A2
Mean 43.6
Standard deviation 9.6
Values 50 37
[52]
HepG2.C3A AP2A2
Mean 34.8
Standard deviation 12
Values 43 26
[53]
HuH.7 AP2A2
Mean 36.5
Standard deviation 2.7
Values 39 36 34
[54]
SNU475 AP2A2
Mean 27.1
Standard deviation 8.1
Values 33 21
[55]
THLE AP2A2
Mean 23.9
Standard deviation 4.3
Values 21 27
[56]
liver AP2A2
Mean 18.6
Standard deviation 3.8
Values 21 19 13 22
[57]
ref_hepatocyte ARRB2
Mean 7.58
Standard deviation 4.1
Values 14 4.4 3.6 8.2 7.8
[58]
HepG2 ARRB2
Mean 18.8
Standard deviation 5.4
Values 23 15
[59]
HepG2.C3A ARRB2
Mean 21.9
Standard deviation 3.9
Values 25 19
[60]
HuH.7 ARRB2
Mean 20.3
Standard deviation 3.2
Values 20 17 23
[61]
SNU475 ARRB2
Mean 5.59
Standard deviation 0.33
Values 5.4 5.8
[62]
THLE ARRB2
Mean 10.9
Standard deviation 0.23
Values 11 11
[63]
liver ARRB2
Mean 5.88
Standard deviation 3.8
Values 9.3 2.5 9.1 2.6
[64]
ref_hepatocyte FZD4
Mean 2.69
Standard deviation 3.7
Values 9.2 0.68 0.82 1.2 1.5
[65]
HepG2 FZD4
Mean 101
Standard deviation 33
Values 78 1.2e+02
[66]
HepG2.C3A FZD4
Mean 43.1
Standard deviation 1.2
Values 42 44
[67]
HuH.7 FZD4
Mean 21.2
Standard deviation 1.5
Values 22 22 20
[68]
SNU475 FZD4
Mean 7.99
Standard deviation 1.3
Values 8.9 7
[69]
THLE FZD4
Mean 5.63
Standard deviation 0.2
Values 5.5 5.8
[70]
liver FZD4
Mean 29.5
Standard deviation 13
Values 17 44 19 38
[71]
ref_hepatocyte PRKCA
Mean 2.45
Standard deviation 2.1
Values 2.7 6 1.1 1.2 1.2
[72]
HepG2 PRKCA
Mean 38.7
Standard deviation 5.6
Values 35 43
[73]
HepG2.C3A PRKCA
Mean 35.5
Standard deviation 4.5
Values 32 39
[74]
HuH.7 PRKCA
Mean 43.7
Standard deviation 11
Values 54 44 33
[75]
SNU475 PRKCA
Mean 20
Standard deviation 4.3
Values 17 23
[76]
THLE PRKCA
Mean 28.8
Standard deviation 11
Values 21 36
[77]
liver PRKCA
Mean 13.2
Standard deviation 7.1
Values 11 17 4.7 21
[78]
ref_hepatocyte DVL2
Mean 2.34
Standard deviation 0.94
Values 3.3 0.77 2.7 2.5 2.4
[79]
HepG2 DVL2
Mean 22.4
Standard deviation 2.6
Values 24 21
[80]
HepG2.C3A DVL2
Mean 16.8
Standard deviation 0.55
Values 17 16
[81]
HuH.7 DVL2
Mean 31.8
Standard deviation 1.9
Values 30 34 32
[82]
SNU475 DVL2
Mean 20
Standard deviation 2.6
Values 22 18
[83]
THLE DVL2
Mean 17.6
Standard deviation 1.2
Values 17 18
[84]
liver DVL2
Mean 3.34
Standard deviation 0.75
Values 3.5 3.2 2.5 4.3
[85]
ref_hepatocyte WNT5A
Mean 0.261
Standard deviation 0.17
Values 0 0.4 0.23 0.25 0.43
[86]
HepG2 WNT5A
Mean 0.063
Standard deviation 0.041
Values 0.092 0.034
[87]
HepG2.C3A WNT5A
Mean 0.0565
Standard deviation 0.011
Values 0.049 0.064
[88]
HuH.7 WNT5A
Mean 0.122
Standard deviation 0.062
Values 0.18 0.13 0.056
[89]
SNU475 WNT5A
Mean 46.2
Standard deviation 6.6
Values 51 42
[90]
THLE WNT5A
Mean 154
Standard deviation 20
Values 1.7e+02 1.4e+02
[91]
liver WNT5A
Mean 0.919
Standard deviation 0.41
Values 0.54 1.3 0.59 1.2
[92]
ref_hepatocyte PRKCB
Mean 0.255
Standard deviation 0.29
Values 0 0 0.4 0.2 0.67
[93]
HepG2 PRKCB
Mean 0.00501
Standard deviation 0.001
Values 0.0057 0.0043
[94]
HepG2.C3A PRKCB
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[95]
HuH.7 PRKCB
Mean 0
Standard deviation 0
Values 0 0 0
[96]
SNU475 PRKCB
Mean 2.62
Standard deviation 2.8
Values 0.61 4.6
[97]
THLE PRKCB
Mean 0.0742
Standard deviation 0.037
Values 0.1 0.048
[98]
liver PRKCB
Mean 4.2
Standard deviation 2.1
Values 2.7 6.8 2.2 5
[99]
ref_hepatocyte PRKCG
Mean 0.031
Standard deviation 0.057
Values 0 0 0.13 0 0.024
[100]
HepG2 PRKCG
Mean 0.0387
Standard deviation 0.043
Values 0.069 0.0086
[101]
HepG2.C3A PRKCG
Mean 0.055
Standard deviation 0.032
Values 0.078 0.032
[102]
HuH.7 PRKCG
Mean 0.0101
Standard deviation 0.0024
Values 0.0082 0.013 0.0094
[103]
SNU475 PRKCG
Mean 0.0272
Standard deviation 0.019
Values 0.014 0.041
[104]
THLE PRKCG
Mean 0.0287
Standard deviation 0.018
Values 0.041 0.016
[105]
liver PRKCG
Mean 0
Standard deviation 0
Values 0 0 0 0