REACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD2_FZD5_AND_ROR2 Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CLTA Clathrin light chain A [1] -1.83[2] -1.85[3] -2.28[4] -2.65[5] -2.61[6] -3.27[7]
2 CLTB Clathrin light chain B [8] -0.52[9] -2.37[10] -3.10[11] -2.84[12] -2.80[13] -2.30[14]
3 AP2M1 AP-2 complex subunit mu [15] 0.26[16] 0.23[17] -0.82[18] 0.79[19] 0.97[20] -0.17[21]
4 AP2S1 AP-2 complex subunit sigma [22] -1.58[23] -1.43[24] -1.28[25] -0.93[26] -0.83[27] -1.03[28]
5 CLTC Clathrin heavy chain 1 [29] 1.66[30] 1.92[31] 1.55[32] 1.49[33] 1.30[34] 2.45[35]
6 AP2A1 AP-2 complex subunit alpha-1 [36] 1.25[37] 1.08[38] 1.37[39] 1.21[40] 0.96[41] 0.95[42]
7 AP2B1 AP-2 complex subunit beta [43] 2.28[44] 2.18[45] 3.36[46] 2.36[47] 1.89[48] 0.93[49]
8 AP2A2 AP-2 complex subunit alpha-2 [50] 1.31[51] 1.31[52] 0.89[53] 0.65[54] -0.02[55] 0.67[56]
9 FZD5 Frizzled-5 [57] 1.01[58] 2.05[59] 2.49[60] -1.33[61] -2.96[62] 2.58[63]
10 WNT5A Protein Wnt-5a [64] -3.15[65] -2.98[66] -2.35[67] 6.40[68] 7.65[69] 1.31[70]
11 FZD2 Frizzled-2 [71] 1.19[72] -0.26[73] 1.91[74] 6.70[75] 3.82[76] -0.36[77]
12 ROR1 Inactive tyrosine-protein kinase transmembrane receptor ROR1 [78] -0.55[79] -1.08[80] 4.32[81] 5.46[82] 4.83[83] 1.73[84]
13 ROR2 Tyrosine-protein kinase transmembrane receptor ROR2 [85] -2.64[86] [87] -1.33[88] 6.59[89] 7.93[90] 3.55[91]
[1]
ref_hepatocyte CLTA
Mean 139
Standard deviation 77
Values 2e+02 2.3e+02 1.4e+02 74 53
[2]
HepG2 CLTA
Mean 83.5
Standard deviation 9.9
Values 91 77
[3]
HepG2.C3A CLTA
Mean 65.7
Standard deviation 0.97
Values 66 65
[4]
HuH.7 CLTA
Mean 68.1
Standard deviation 8
Values 60 68 76
[5]
SNU475 CLTA
Mean 46.3
Standard deviation 2.6
Values 48 45
[6]
THLE CLTA
Mean 67.1
Standard deviation 17
Values 55 79
[7]
liver CLTA
Mean 20.5
Standard deviation 13
Values 32 10 31 8.4
[8]
ref_hepatocyte CLTB
Mean 49.9
Standard deviation 29
Values 19 72 89 39 30
[9]
HepG2 CLTB
Mean 74.4
Standard deviation 33
Values 98 51
[10]
HepG2.C3A CLTB
Mean 16.5
Standard deviation 2.8
Values 15 18
[11]
HuH.7 CLTB
Mean 13.9
Standard deviation 2.8
Values 14 11 17
[12]
SNU475 CLTB
Mean 14.6
Standard deviation 1.2
Values 14 15
[13]
THLE CLTB
Mean 21
Standard deviation 2.5
Values 19 23
[14]
liver CLTB
Mean 14.4
Standard deviation 8.2
Values 24 8.6 19 6.4
[15]
ref_hepatocyte AP2M1
Mean 41.6
Standard deviation 13
Values 28 39 35 63 44
[16]
HepG2 AP2M1
Mean 107
Standard deviation 14
Values 97 1.2e+02
[17]
HepG2.C3A AP2M1
Mean 83
Standard deviation 17
Values 71 95
[18]
HuH.7 AP2M1
Mean 56.4
Standard deviation 14
Values 67 40 62
[19]
SNU475 AP2M1
Mean 150
Standard deviation 32
Values 1.7e+02 1.3e+02
[20]
THLE AP2M1
Mean 241
Standard deviation 26
Values 2.2e+02 2.6e+02
[21]
liver AP2M1
Mean 52.8
Standard deviation 26
Values 55 35 89 32
[22]
ref_hepatocyte AP2S1
Mean 38.3
Standard deviation 23
Values 13 36 20 57 66
[23]
HepG2 AP2S1
Mean 27.5
Standard deviation 0.19
Values 28 27
[24]
HepG2.C3A AP2S1
Mean 24.1
Standard deviation 3.4
Values 22 27
[25]
HuH.7 AP2S1
Mean 37.6
Standard deviation 15
Values 43 21 49
[26]
SNU475 AP2S1
Mean 42
Standard deviation 3.1
Values 44 40
[27]
THLE AP2S1
Mean 63.5
Standard deviation 6.7
Values 59 68
[28]
liver AP2S1
Mean 26.7
Standard deviation 27
Values 53 3.8 46 3.4
[29]
ref_hepatocyte CLTC
Mean 30
Standard deviation 17
Values 53 42 13 19 24
[30]
HepG2 CLTC
Mean 203
Standard deviation 93
Values 1.4e+02 2.7e+02
[31]
HepG2.C3A CLTC
Mean 193
Standard deviation 28
Values 1.7e+02 2.1e+02
[32]
HuH.7 CLTC
Mean 209
Standard deviation 37
Values 2.5e+02 2.1e+02 1.7e+02
[33]
SNU475 CLTC
Mean 176
Standard deviation 18
Values 1.9e+02 1.6e+02
[34]
THLE CLTC
Mean 218
Standard deviation 18
Values 2.1e+02 2.3e+02
[35]
liver CLTC
Mean 234
Standard deviation 1.1e+02
Values 1.2e+02 3.7e+02 1.8e+02 2.7e+02
[36]
ref_hepatocyte AP2A1
Mean 10.6
Standard deviation 3.7
Values 6.9 8.6 9.7 17 11
[37]
HepG2 AP2A1
Mean 54
Standard deviation 4.5
Values 57 51
[38]
HepG2.C3A AP2A1
Mean 38.1
Standard deviation 9.3
Values 45 32
[39]
HuH.7 AP2A1
Mean 65.1
Standard deviation 18
Values 85 50 60
[40]
SNU475 AP2A1
Mean 51.3
Standard deviation 9.3
Values 58 45
[41]
THLE AP2A1
Mean 60.6
Standard deviation 7.6
Values 55 66
[42]
liver AP2A1
Mean 29.1
Standard deviation 3.1
Values 28 27 27 34
[43]
ref_hepatocyte AP2B1
Mean 9
Standard deviation 4.1
Values 11 15 5.6 5.9 7.2
[44]
HepG2 AP2B1
Mean 93.9
Standard deviation 10
Values 87 1e+02
[45]
HepG2.C3A AP2B1
Mean 69.3
Standard deviation 14
Values 79 59
[46]
HuH.7 AP2B1
Mean 220
Standard deviation 43
Values 2.7e+02 2e+02 1.9e+02
[47]
SNU475 AP2B1
Mean 96.9
Standard deviation 32
Values 1.2e+02 74
[48]
THLE AP2B1
Mean 98.4
Standard deviation 18
Values 86 1.1e+02
[49]
liver AP2B1
Mean 24.4
Standard deviation 6.6
Values 18 34 23 23
[50]
ref_hepatocyte AP2A2
Mean 8.24
Standard deviation 1.1
Values 7.8 6.8 8.3 9.9 8.3
[51]
HepG2 AP2A2
Mean 43.6
Standard deviation 9.6
Values 50 37
[52]
HepG2.C3A AP2A2
Mean 34.8
Standard deviation 12
Values 43 26
[53]
HuH.7 AP2A2
Mean 36.5
Standard deviation 2.7
Values 39 36 34
[54]
SNU475 AP2A2
Mean 27.1
Standard deviation 8.1
Values 33 21
[55]
THLE AP2A2
Mean 23.9
Standard deviation 4.3
Values 21 27
[56]
liver AP2A2
Mean 18.6
Standard deviation 3.8
Values 21 19 13 22
[57]
ref_hepatocyte FZD5
Mean 6.07
Standard deviation 3.7
Values 12 4.4 2.3 5.6 5.8
[58]
HepG2 FZD5
Mean 26.3
Standard deviation 2.4
Values 28 25
[59]
HepG2.C3A FZD5
Mean 42.7
Standard deviation 15
Values 53 32
[60]
HuH.7 FZD5
Mean 81.4
Standard deviation 28
Values 76 1.1e+02 56
[61]
SNU475 FZD5
Mean 5.07
Standard deviation 1.9
Values 6.5 3.7
[62]
THLE FZD5
Mean 2.29
Standard deviation 0.46
Values 2 2.6
[63]
liver FZD5
Mean 51.7
Standard deviation 15
Values 73 42 47 44
[64]
ref_hepatocyte WNT5A
Mean 0.261
Standard deviation 0.17
Values 0 0.4 0.23 0.25 0.43
[65]
HepG2 WNT5A
Mean 0.063
Standard deviation 0.041
Values 0.092 0.034
[66]
HepG2.C3A WNT5A
Mean 0.0565
Standard deviation 0.011
Values 0.049 0.064
[67]
HuH.7 WNT5A
Mean 0.122
Standard deviation 0.062
Values 0.18 0.13 0.056
[68]
SNU475 WNT5A
Mean 46.2
Standard deviation 6.6
Values 51 42
[69]
THLE WNT5A
Mean 154
Standard deviation 20
Values 1.7e+02 1.4e+02
[70]
liver WNT5A
Mean 0.919
Standard deviation 0.41
Values 0.54 1.3 0.59 1.2
[71]
ref_hepatocyte FZD2
Mean 0.12
Standard deviation 0.086
Values 0.092 0.06 0.27 0.078 0.098
[72]
HepG2 FZD2
Mean 0.586
Standard deviation 0.0023
Values 0.58 0.59
[73]
HepG2.C3A FZD2
Mean 0.171
Standard deviation 0.075
Values 0.22 0.12
[74]
HuH.7 FZD2
Mean 1.07
Standard deviation 0.18
Values 0.94 0.99 1.3
[75]
SNU475 FZD2
Mean 26
Standard deviation 11
Values 34 18
[76]
THLE FZD2
Mean 4.99
Standard deviation 1.5
Values 3.9 6.1
[77]
liver FZD2
Mean 0.132
Standard deviation 0.11
Values 0.024 0.1 0.13 0.28
[78]
ref_hepatocyte ROR1
Mean 0.114
Standard deviation 0.1
Values 0.035 0.15 0.26 0 0.12
[79]
HepG2 ROR1
Mean 0.167
Standard deviation 0.074
Values 0.11 0.22
[80]
HepG2.C3A ROR1
Mean 0.0915
Standard deviation 0.0081
Values 0.097 0.086
[81]
HuH.7 ROR1
Mean 5.41
Standard deviation 2.3
Values 7.9 3.4 5
[82]
SNU475 ROR1
Mean 10.5
Standard deviation 5.2
Values 14 6.9
[83]
THLE ROR1
Mean 9.5
Standard deviation 2.3
Values 7.9 11
[84]
liver ROR1
Mean 0.536
Standard deviation 0.24
Values 0.26 0.83 0.44 0.62
[85]
ref_hepatocyte ROR2
Mean 0.025
Standard deviation 0.056
Values 0 0 0.12 0 0
[86]
HepG2 ROR2
Mean 0.0086
Standard deviation 0.012
Values 0.017 0
[87]
HepG2.C3A ROR2
Mean 0
Standard deviation 0
Values 0 0
[88]
HuH.7 ROR2
Mean 0.0238
Standard deviation 0.022
Values 0.049 0.013 0.0094
[89]
SNU475 ROR2
Mean 5.04
Standard deviation 0.22
Values 4.9 5.2
[90]
THLE ROR2
Mean 17.9
Standard deviation 1.3
Values 17 19
[91]
liver ROR2
Mean 0.417
Standard deviation 0.15
Values 0.21 0.54 0.39 0.53