REACTOME_VISUAL_PHOTOTRANSDUCTION | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | APOA2 | Apolipoprotein A-II | [1] | -1.12[2] | -0.65[3] | -0.87[4] | -9.34[5] | -7.73[6] | -1.13[7] |
2 | APOA1 | Apolipoprotein A-I | [8] | -1.10[9] | -0.40[10] | -2.23[11] | -9.85[12] | -8.63[13] | -0.16[14] |
3 | APOC3 | Apolipoprotein C-III | [15] | -4.96[16] | -2.86[17] | -3.67[18] | -12.47[19] | -11.71[20] | -0.65[21] |
4 | RBP4 | Retinol-binding protein 4 | [22] | -2.43[23] | -1.82[24] | -0.29[25] | -8.73[26] | -6.84[27] | -0.13[28] |
5 | APOE | Apolipoprotein E | [29] | -0.51[30] | -0.72[31] | 0.06[32] | -6.57[33] | -4.43[34] | -0.84[35] |
6 | TTR | Transthyretin | [36] | -3.97[37] | -2.23[38] | -2.56[39] | -11.50[40] | -9.82[41] | -1.40[42] |
7 | APOC2 | Apolipoprotein C-II | [43] | [44] | [45] | [46] | [47] | [48] | [49] |
8 | AKR1C1 | Aldo-keto reductase family 1 member C1 | [50] | 0.39[51] | -0.52[52] | -3.43[53] | 1.35[54] | -2.06[55] | -3.25[56] |
9 | HSD17B6 | 17-beta-hydroxysteroid dehydrogenase type 6 | [57] | -7.36[58] | -7.75[59] | -6.01[60] | -1.81[61] | -4.11[62] | 0.67[63] |
10 | AKR1C3 | Aldo-keto reductase family 1 member C3 | [64] | 0.87[65] | 0.91[66] | -4.93[67] | 4.59[68] | -1.10[69] | -1.20[70] |
11 | RDH16 | Retinol dehydrogenase 16 | [71] | -9.11[72] | -7.71[73] | -6.67[74] | -7.10[75] | -6.36[76] | 0.30[77] |
12 | APOB | Apolipoprotein B-100 | [78] | 5.08[79] | 5.27[80] | 5.25[81] | -3.24[82] | -1.79[83] | 5.86[84] |
13 | APOM | Apolipoprotein M | [85] | -1.57[86] | 1.93[87] | 0.14[88] | -4.31[89] | -3.78[90] | -0.16[91] |
14 | GPC3 | Glypican-3 | [92] | 5.32[93] | 5.17[94] | 4.60[95] | -3.70[96] | -2.11[97] | -7.24[98] |
15 | AKR1C4 | Aldo-keto reductase family 1 member C4 | [99] | -5.92[100] | -4.14[101] | -3.93[102] | -6.46[103] | -10.56[104] | 0.11[105] |
16 | SDC1 | Syndecan-1 | [106] | 2.65[107] | 1.61[108] | 2.76[109] | 1.85[110] | 0.93[111] | 1.77[112] |
17 | SDC4 | Syndecan-4 | [113] | 3.45[114] | 2.55[115] | 2.12[116] | 2.45[117] | 5.38[118] | 0.89[119] |
18 | DHRS3 | Short-chain dehydrogenase/reductase 3 | [120] | 0.81[121] | 1.30[122] | 0.84[123] | 2.21[124] | 3.27[125] | 1.31[126] |
19 | AKR1B10 | Aldo-keto reductase family 1 member B10 | [127] | 2.24[128] | 0.63[129] | -3.67[130] | 6.99[131] | -1.47[132] | -2.93[133] |
20 | RDH11 | Retinol dehydrogenase 11 | [134] | 1.02[135] | 1.94[136] | 2.73[137] | 2.53[138] | 4.00[139] | 1.50[140] |
21 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | [141] | 4.15[142] | 3.59[143] | 3.91[144] | 5.49[145] | 6.67[146] | -0.25[147] |
22 | SDC2 | Syndecan-2 | [148] | 3.55[149] | 3.92[150] | 4.35[151] | 4.02[152] | 2.19[153] | 1.62[154] |
23 | METAP2 | Methionine aminopeptidase 2 | [155] | 2.02[156] | 2.52[157] | 3.88[158] | 3.76[159] | 5.17[160] | -0.27[161] |
24 | CALM1 | Calmodulin-1 | [162] | 3.22[163] | 2.67[164] | 3.93[165] | 5.79[166] | 6.45[167] | 2.61[168] |
25 | APOA4 | Apolipoprotein A-IV | [169] | 0.49[170] | 1.66[171] | -3.53[172] | -8.47[173] | -8.53[174] | 2.28[175] |
26 | RDH5 | 11-cis retinol dehydrogenase | [176] | -4.65[177] | -3.26[178] | -2.45[179] | -4.27[180] | -2.36[181] | -1.82[182] |
27 | RETSAT | All-trans-retinol 13,14-reductase | [183] | 2.98[184] | 3.04[185] | 2.70[186] | 3.33[187] | 4.13[188] | 1.42[189] |
28 | FNTA | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | 2.24[190] | 2.63[191] | 3.97[192] | 2.59[193] | 4.48[194] | 0.09[195] | |
29 | NMT1 | Glycylpeptide N-tetradecanoyltransferase 1 | [196] | 4.62[197] | 3.89[198] | 4.95[199] | 4.97[200] | 6.52[201] | 1.42[202] |
30 | LDLR | Low-density lipoprotein receptor | [203] | 3.33[204] | 3.59[205] | 5.40[206] | 3.31[207] | 5.88[208] | 2.22[209] |
31 | LRP10 | Low-density lipoprotein receptor-related protein 10 | [210] | 4.53[211] | 1.54[212] | 4.29[213] | 5.32[214] | 6.87[215] | 1.63[216] |
32 | LRP1 | Prolow-density lipoprotein receptor-related protein 1 | [217] | 6.97[218] | 4.68[219] | 6.46[220] | 6.56[221] | 7.91[222] | 6.14[223] |
33 | DHRS9 | Dehydrogenase/reductase SDR family member 9 | [224] | -5.39[225] | -6.15[226] | -6.64[227] | -1.78[228] | 0.02[229] | -4.86[230] |
34 | GPC1 | Glypican-1 | [231] | 3.64[232] | -0.27[233] | -3.48[234] | 6.66[235] | 6.82[236] | 0.46[237] |
35 | CYP4V2 | Cytochrome P450 4V2 | [238] | -0.10[239] | 1.07[240] | -0.07[241] | 0.34[242] | 2.26[243] | 2.75[244] |
36 | METAP1 | Methionine aminopeptidase 1 | [245] | 3.58[246] | 3.15[247] | 4.04[248] | 4.12[249] | 6.10[250] | 0.33[251] |
37 | BCO2 | Beta,beta-carotene 9',10'-oxygenase | [252] | -1.32[253] | -0.60[254] | -1.06[255] | 0.49[256] | 3.02[257] | 2.51[258] |
38 | RDH10 | Retinol dehydrogenase 10 | [259] | 3.27[260] | 3.39[261] | 3.14[262] | 4.65[263] | 4.63[264] | 2.00[265] |
39 | AGRN | Agrin | [266] | 7.30[267] | 6.14[268] | 6.44[269] | 7.74[270] | 8.17[271] | 2.07[272] |
40 | GNB5 | Guanine nucleotide-binding protein subunit beta-5 | [273] | 3.24[274] | 2.70[275] | 4.52[276] | 4.99[277] | 6.50[278] | 1.88[279] |
41 | RBP1 | Retinol-binding protein 1 | [280] | 5.28[281] | -0.01[282] | 2.07[283] | 3.02[284] | 0.60[285] | 1.84[286] |
42 | NMT2 | Glycylpeptide N-tetradecanoyltransferase 2 | [287] | 2.82[288] | 3.53[289] | 2.45[290] | 5.36[291] | 6.60[292] | 2.75[293] |
43 | RBP2 | Retinol-binding protein 2 | [294] | -2.10[295] | 0.23[296] | 6.98[297] | -1.61[298] | -0.36[299] | -7.13[300] |
44 | CAMKMT | Calmodulin-lysine N-methyltransferase | [301] | 2.17[302] | 1.76[303] | 1.81[304] | 0.94[305] | 2.98[306] | -0.84[307] |
45 | PRKCA | Protein kinase C alpha type | [308] | 5.98[309] | 5.44[310] | 6.60[311] | 6.35[312] | 8.10[313] | 2.91[314] |
46 | GPC6 | Glypican-6 | [315] | 5.75[316] | 4.34[317] | 5.74[318] | 8.15[319] | 7.61[320] | 4.25[321] |
47 | RGS9 | Regulator of G-protein signaling 9 | [322] | -1.86[323] | -4.17[324] | -3.96[325] | 2.62[326] | 1.97[327] | -1.86[328] |
48 | CNGA1 | cGMP-gated cation channel alpha-1 | [329] | -5.07[330] | -1.60[331] | 0.98[332] | -3.56[333] | -1.01[334] | 1.91[335] |
49 | NAPEPLD | N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D | [336] | 2.71[337] | 3.17[338] | 4.88[339] | 5.10[340] | 4.84[341] | 3.05[342] |
50 | HSD17B1 | Estradiol 17-beta-dehydrogenase 1 | [343] | 3.94[344] | 4.01[345] | 4.20[346] | 4.16[347] | 5.28[348] | 0.56[349] |
51 | MYO7A | Unconventional myosin-VIIa | [350] | 4.55[351] | 4.31[352] | 3.17[353] | 0.94[354] | -0.14[355] | 4.57[356] |
52 | SLC24A1 | Sodium/potassium/calcium exchanger 1 | [357] | 3.71[358] | 4.14[359] | 4.25[360] | 4.08[361] | 5.38[362] | 1.25[363] |
53 | SDC3 | Syndecan-3 | [364] | 5.94[365] | -0.87[366] | 3.95[367] | 7.33[368] | 8.99[369] | 3.74[370] |
54 | FNTB | Protein farnesyltransferase subunit beta | [371] | 2.06[372] | 1.21[373] | -0.25[374] | 2.39[375] | 3.11[376] | -1.30[377] |
55 | GUCA1B | Guanylyl cyclase-activating protein 2 | [378] | 0.31[379] | 1.31[380] | 3.49[381] | 2.51[382] | 3.36[383] | -0.98[384] |
56 | RDH12 | Retinol dehydrogenase 12 | [385] | 1.92[386] | 3.49[387] | -2.49[388] | -0.40[389] | 1.29[390] | 1.34[391] |
57 | LRP8 | Low-density lipoprotein receptor-related protein 8 | [392] | 5.57[393] | 5.76[394] | 6.92[395] | 7.71[396] | 9.02[397] | -1.05[398] |
58 | HSPG2 | Basement membrane-specific heparan sulfate proteoglycan core protein | 10.76[399] | 8.42[400] | 9.61[401] | 10.25[402] | 11.80[403] | 7.36[404] | |
59 | GPC4 | Glypican-4 | [405] | 2.13[406] | -2.50[407] | 2.07[408] | 9.68[409] | 3.30[410] | 1.93[411] |
60 | LRP12 | Low-density lipoprotein receptor-related protein 12 | [412] | 5.36[413] | 1.86[414] | 6.00[415] | 10.14[416] | 10.88[417] | 2.89[418] |
61 | LPL | Lipoprotein lipase | [419] | [420] | [421] | -4.05[422] | 4.77[423] | 2.52[424] | 0.75[425] |
62 | GRK4 | G protein-coupled receptor kinase 4 | [426] | 2.96[427] | 1.45[428] | 3.82[429] | 4.37[430] | 5.85[431] | 1.96[432] |
63 | PDE6B | Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta | [433] | 2.18[434] | 1.20[435] | 1.08[436] | 5.65[437] | 3.84[438] | 1.71[439] |
64 | PDE6A | Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha | [440] | 3.20[441] | 3.31[442] | 4.15[443] | 5.67[444] | 7.30[445] | 2.47[446] |
65 | LRAT | Lecithin retinol acyltransferase | [447] | 1.44[448] | 1.43[449] | 1.02[450] | 2.77[451] | 4.75[452] | 6.19[453] |
66 | LRP2 | Low-density lipoprotein receptor-related protein 2 | [454] | 5.45[455] | 1.54[456] | 11.02[457] | 1.93[458] | 3.04[459] | 7.21[460] |
67 | PRKCQ | Protein kinase C theta type | [461] | 4.04[462] | -0.09[463] | [464] | 6.33[465] | 9.22[466] | 3.08[467] |
68 | GNAT1 | Guanine nucleotide-binding protein G(t) subunit alpha-1 | [468] | 0.35[469] | 3.11[470] | 3.52[471] | 1.96[472] | [473] | 2.50[474] |
69 | GPC5 | Glypican-5 | [475] | -0.05[476] | -1.94[477] | 3.24[478] | 0.96[479] | 2.86[480] | 4.56[481] |
70 | ABCA4 | Retinal-specific ATP-binding cassette transporter | [482] | 7.06[483] | 2.68[484] | 5.00[485] | 7.19[486] | 3.97[487] | 4.45[488] |
71 | GPC2 | Glypican-2 | [489] | 6.05[490] | 4.91[491] | 7.73[492] | 7.54[493] | 7.77[494] | -2.08[495] |
72 | PLB1 | Phospholipase B1, membrane-associated | [496] | 7.66[497] | 1.80[498] | 3.87[499] | 7.77[500] | 6.92[501] | 4.17[502] |
73 | CNGB1 | Cyclic nucleotide-gated cation channel beta-1 | [503] | 6.45[504] | 4.62[505] | 2.99[506] | 4.65[507] | 6.65[508] | -1.23[509] |
74 | STRA6 | Receptor for retinol uptake STRA6 | [510] | 9.05[511] | 4.43[512] | 1.75[513] | 12.49[514] | 10.24[515] | -1.98[516] |
75 | CLPS | Colipase | [517] | [518] | [519] | [520] | [521] | 1.50[522] | 0.14[523] |
76 | PDE6G | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamm | 7.93[524] | 8.50[525] | 4.23[526] | 7.19[527] | 6.88[528] | 4.07[529] | |
77 | GPIHBP1 | Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 | [530] | 0.27[531] | [532] | 0.95[533] | 2.37[534] | 6.15[535] | |
78 | GUCY2D | Retinal guanylyl cyclase 1 | [536] | [537] | [538] | 9.22[539] | 4.86[540] | 8.55[541] | 3.31[542] |
79 | RLBP1 | Retinaldehyde-binding protein 1 | [543] | [544] | [545] | [546] | [547] | [548] | [549] |
80 | SDR9C7 | Short-chain dehydrogenase/reductase family 9C member 7 | [550] | [551] | [552] | [553] | [554] | [555] | [556] |
81 | PPEF1 | Serine/threonine-protein phosphatase with EF-hands 1 | [557] | [558] | [559] | [560] | [561] | [562] | [563] |
82 | SAG | S-arrestin | [564] | [565] | [566] | [567] | [568] | [569] | [570] |
83 | RHO | Rhodopsin | [571] | [572] | [573] | [574] | [575] | [576] | [577] |
84 | AWAT2 | Acyl-CoA wax alcohol acyltransferase 2 | [578] | [579] | [580] | [581] | [582] | [583] | [584] |
85 | PNLIP | Pancreatic triacylglycerol lipase | [585] | [586] | [587] | [588] | [589] | [590] | [591] |
86 | GRK1 | Rhodopsin kinase | [592] | [593] | [594] | [595] | [596] | [597] | [598] |
87 | RPE65 | Retinoid isomerohydrolase | [599] | [600] | [601] | [602] | [603] | [604] | [605] |
88 | RDH8 | Retinol dehydrogenase 8 | [606] | [607] | [608] | [609] | [610] | [611] | [612] |
89 | OPN1MW | Medium-wave-sensitive opsin 1 | [613] | [614] | [615] | [616] | [617] | [618] | [619] |
90 | OPN1SW | Short-wave-sensitive opsin 1 | [620] | [621] | [622] | [623] | [624] | [625] | [626] |
91 | GNGT1 | Guanine nucleotide-binding protein G(T) subunit gamma-T1 | [627] | [628] | [629] | [630] | [631] | [632] | [633] |
92 | RBP3 | Retinol-binding protein 3 | [634] | [635] | [636] | [637] | [638] | [639] | [640] |
93 | GUCY2F | Retinal guanylyl cyclase 2 | [641] | [642] | [643] | [644] | [645] | [646] | [647] |
94 | GUCA1A | Guanylyl cyclase-activating protein 1 | [648] | [649] | [650] | [651] | [652] | [653] | [654] |
95 | RCVRN | Recoverin | [655] | [656] | [657] | [658] | [659] | [660] | [661] |
96 | GRK7 | Rhodopsin kinase | [662] | [663] | [664] | [665] | [666] | [667] | [668] |
97 | RGS9BP | Regulator of G-protein signaling 9-binding protein | [669] | [670] | [671] | [672] | [673] | [674] | [675] |
98 | BCO1 | Beta,beta-carotene 15,15'-dioxygenase | [676] | [677] | [678] | [679] | [680] | [681] | [682] |
99 | OPN1LW | Long-wave-sensitive opsin 1 | [683] | [684] | [685] | [686] | [687] | [688] | [689] |
100 | GUCA1C | Guanylyl cyclase-activating protein 3 | [690] | [691] | [692] | [693] | [694] | [695] | [696] |