REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_GENE_EXPRESSION | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | SERPINE1 | Plasminogen activator inhibitor 1 | [1] | 0.59[2] | 0.60[3] | -5.40[4] | -3.31[5] | 0.90[6] | -4.69[7] |
2 | NAMPT | Nicotinamide phosphoribosyltransferase | [8] | -3.26[9] | -2.87[10] | -1.56[11] | -0.39[12] | -0.49[13] | 0.16[14] |
3 | BHLHE40 | Class E basic helix-loop-helix protein 40 | [15] | -0.41[16] | -0.41[17] | -0.48[18] | -0.90[19] | -2.87[20] | -1.89[21] |
4 | F7 | Coagulation factor VII | [22] | -3.33[23] | -1.24[24] | -1.72[25] | -10.52[26] | -12.86[27] | -0.27[28] |
5 | RXRA | Retinoic acid receptor RXR-alpha | [29] | -0.60[30] | -1.01[31] | 0.57[32] | 0.51[33] | -2.29[34] | 1.33[35] |
6 | KLF15 | Krueppel-like factor 15 | [36] | -4.34[37] | -6.44[38] | -0.81[39] | -10.07[40] | -6.01[41] | -0.69[42] |
7 | CARM1 | Histone-arginine methyltransferase CARM1 | [43] | 0.91[44] | 0.15[45] | 1.21[46] | 0.25[47] | -1.43[48] | -1.83[49] |
8 | ARNTL | Aryl hydrocarbon receptor nuclear translocator-like protein 1 | [50] | -2.62[51] | -2.32[52] | -2.55[53] | -0.55[54] | -2.83[55] | -0.03[56] |
9 | TBL1XR1 | F-box-like/WD repeat-containing protein TBL1XR1 | [57] | 0.54[58] | 0.86[59] | 2.25[60] | 2.91[61] | 0.00[62] | 2.06[63] |
10 | TBL1X | F-box-like/WD repeat-containing protein TBL1X | [64] | 0.80[65] | 0.99[66] | 3.29[67] | -3.90[68] | -0.88[69] | 0.93[70] |
11 | PPARA | Peroxisome proliferator-activated receptor alpha | [71] | 0.13[72] | 0.90[73] | 2.49[74] | 0.54[75] | -2.77[76] | 3.33[77] |
12 | MED1 | Mediator of RNA polymerase II transcription subunit 1 | [78] | 2.00[79] | 1.12[80] | 2.76[81] | 2.70[82] | 0.39[83] | 0.46[84] |
13 | NPAS2 | Neuronal PAS domain-containing protein 2 | [85] | 1.04[86] | 1.50[87] | 1.82[88] | -1.88[89] | -2.12[90] | -1.00[91] |
14 | NCOA6 | Nuclear receptor coactivator 6 | [92] | 1.66[93] | 1.30[94] | 2.24[95] | 3.06[96] | -0.16[97] | 0.59[98] |
15 | ARNTL2 | Aryl hydrocarbon receptor nuclear translocator-like protein 2 | [99] | 0.22[100] | 0.64[101] | 0.05[102] | 1.14[103] | -0.89[104] | -0.62[105] |
16 | TGS1 | Trimethylguanosine synthase | [106] | 0.05[107] | 0.28[108] | 1.55[109] | 2.22[110] | -0.42[111] | 0.16[112] |
17 | NCOA1 | Nuclear receptor coactivator 1 | [113] | -0.08[114] | 0.28[115] | 1.21[116] | 2.29[117] | -0.73[118] | 1.84[119] |
18 | CREBBP | CREB-binding protein | [120] | 2.36[121] | 1.36[122] | 2.71[123] | 3.25[124] | 0.79[125] | 2.42[126] |
19 | CLOCK | Circadian locomoter output cycles protein kaput | [127] | 0.24[128] | 1.24[129] | 1.73[130] | 2.84[131] | 0.99[132] | 2.61[133] |
20 | DBP | D site-binding protein | [134] | -1.12[135] | -1.39[136] | 2.19[137] | 1.76[138] | -3.81[139] | -2.55[140] |
21 | CHD9 | Chromodomain-helicase-DNA-binding protein 9 | [141] | 0.78[142] | 2.67[143] | 2.65[144] | 2.88[145] | 1.43[146] | 4.11[147] |
22 | NCOA2 | Nuclear receptor coactivator 2 | [148] | 1.04[149] | 1.64[150] | 4.21[151] | 3.70[152] | -0.48[153] | 3.79[154] |
23 | SMARCD3 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfa | 0.93[155] | -0.95[156] | 1.84[157] | 3.76[158] | 1.48[159] | 0.55[160] | |
24 | AVP | Vasopressin-neurophysin 2-copeptin | [161] | -4.60[162] | -2.37[163] | -2.06[164] | [165] | -9.53[166] | -1.88[167] |
25 | BHLHE41 | Class E basic helix-loop-helix protein 41 | [168] | 0.70[169] | -4.83[170] | -0.29[171] | 6.16[172] | 1.77[173] | -1.09[174] |
26 | HELZ2 | Helicase with zinc finger domain 2 | [175] | [176] | [177] | [178] | [179] | [180] | [181] |
27 | NOCT | Nocturnin | [182] | [183] | [184] | [185] | [186] | [187] | [188] |