REACTOME_VEGFR2_MEDIATED_CELL_PROLIFERATION Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CALM1 Calmodulin-1 [1] -1.31[2] -1.53[3] -0.48[4] 0.55[5] -0.23[6] 0.39[7]
2 AHCYL1 S-adenosylhomocysteine hydrolase-like protein 1 [8] -1.15[9] -1.31[10] -0.15[11] -0.02[12] -0.20[13] -0.93[14]
3 VEGFA Vascular endothelial growth factor A [15] -0.17[16] 0.91[17] 0.10[18] -0.59[19] 0.06[20] -0.45[21]
4 NRAS GTPase NRas [22] -0.76[23] -0.58[24] 0.41[25] -0.04[26] -0.52[27] -1.48[28]
5 HRAS GTPase HRas [29] -2.39[30] -3.36[31] -3.56[32] -1.98[33] -2.25[34] -3.89[35]
6 SPHK1 Sphingosine kinase 1 [36] 0.19[37] 0.62[38] -1.28[39] -3.24[40] -1.02[41] -6.23[42]
7 KRAS GTPase KRas [43] -1.90[44] -2.18[45] 0.00[46] -0.23[47] -0.63[48] -0.56[49]
8 PRKCZ Protein kinase C zeta type [50] -0.91[51] -0.79[52] -2.21[53] -3.33[54] -5.58[55] -2.87[56]
9 ITPR2 Inositol 1,4,5-trisphosphate receptor type 2 [57] -0.47[58] 0.72[59] -0.23[60] -1.03[61] -0.94[62] 2.64[63]
10 SRC Proto-oncogene tyrosine-protein kinase Src [64] 1.64[65] 1.36[66] 0.95[67] 1.37[68] 0.49[69] -2.08[70]
11 PRKCD Protein kinase C delta type [71] -0.29[72] -0.30[73] -0.23[74] -1.54[75] -0.43[76] -2.30[77]
12 PDPK1 3-phosphoinositide-dependent protein kinase 1 [78] 0.95[79] 1.88[80] 1.17[81] 0.40[82] 0.74[83] 1.27[84]
13 PLCG1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 2.11[85] 1.46[86] 1.38[87] 1.79[88] 1.23[89] -0.89[90]
14 RASA1 Ras GTPase-activating protein 1 [91] -1.01[92] -0.35[93] 0.33[94] 0.88[95] -0.12[96] -0.02[97]
15 PRKCA Protein kinase C alpha type [98] 1.45[99] 1.23[100] 2.18[101] 1.12[102] 1.42[103] 0.69[104]
16 ITPR3 Inositol 1,4,5-trisphosphate receptor type 3 [105] 3.91[106] 2.50[107] 1.57[108] 1.32[109] 3.44[110] -1.00[111]
17 ITPR1 Inositol 1,4,5-trisphosphate receptor type 1 [112] 1.75[113] 1.38[114] 3.12[115] 1.82[116] 2.63[117] 3.42[118]
18 KDR Vascular endothelial growth factor receptor 2 [119] -7.01[120] -8.93[121] -7.63[122] -2.77[123] 3.64[124] 5.07[125]
19 PRKCB Protein kinase C beta type [126] -8.20[127] -7.26[128] [129] 1.45[130] -3.91[131] 2.30[132]
[1]
ref_hepatocyte CALM1
Mean 29.2
Standard deviation 11
Values 17 40 21 28 40
[2]
HepG2 CALM1
Mean 67.9
Standard deviation 4.3
Values 65 71
[3]
HepG2.C3A CALM1
Mean 62
Standard deviation 16
Values 51 73
[4]
HuH.7 CALM1
Mean 81.9
Standard deviation 15
Values 90 64 92
[5]
SNU475 CALM1
Mean 160
Standard deviation 24
Values 1.8e+02 1.4e+02
[6]
THLE CALM1
Mean 109
Standard deviation 13
Values 1e+02 1.2e+02
[7]
liver CALM1
Mean 127
Standard deviation 70
Values 2.1e+02 80 1.7e+02 57
[8]
ref_hepatocyte AHCYL1
Mean 21.3
Standard deviation 7.5
Values 25 31 12 20 18
[9]
HepG2 AHCYL1
Mean 55.4
Standard deviation 1.1
Values 56 55
[10]
HepG2.C3A AHCYL1
Mean 52.7
Standard deviation 1.2
Values 54 52
[11]
HuH.7 AHCYL1
Mean 75.1
Standard deviation 17
Values 90 56 79
[12]
SNU475 AHCYL1
Mean 78.9
Standard deviation 16
Values 90 67
[13]
THLE AHCYL1
Mean 80.7
Standard deviation 6.3
Values 76 85
[14]
liver AHCYL1
Mean 37.2
Standard deviation 6
Values 43 41 35 30
[15]
ref_hepatocyte VEGFA
Mean 15.4
Standard deviation 8.3
Values 12 5.2 12 22 25
[16]
HepG2 VEGFA
Mean 78.9
Standard deviation 39
Values 1.1e+02 51
[17]
HepG2.C3A VEGFA
Mean 178
Standard deviation 91
Values 2.4e+02 1.1e+02
[18]
HuH.7 VEGFA
Mean 64.6
Standard deviation 7.4
Values 59 62 73
[19]
SNU475 VEGFA
Mean 38.2
Standard deviation 17
Values 26 50
[20]
THLE VEGFA
Mean 70.1
Standard deviation 17
Values 82 58
[21]
liver VEGFA
Mean 37.5
Standard deviation 27
Values 18 70 14 48
[22]
ref_hepatocyte NRAS
Mean 14.4
Standard deviation 13
Values 32 23 9.3 3.3 4.6
[23]
HepG2 NRAS
Mean 49.3
Standard deviation 10
Values 42 57
[24]
HepG2.C3A NRAS
Mean 59.2
Standard deviation 18
Values 47 72
[25]
HuH.7 NRAS
Mean 75.6
Standard deviation 9.1
Values 86 70 71
[26]
SNU475 NRAS
Mean 52.9
Standard deviation 9.2
Values 59 46
[27]
THLE NRAS
Mean 44
Standard deviation 8.9
Values 38 50
[28]
liver NRAS
Mean 17.2
Standard deviation 2.6
Values 14 21 18 16
[29]
ref_hepatocyte HRAS
Mean 11.6
Standard deviation 9
Values 4 27 11 7.4 8.8
[30]
HepG2 HRAS
Mean 12.7
Standard deviation 1.1
Values 14 12
[31]
HepG2.C3A HRAS
Mean 6.96
Standard deviation 1.3
Values 6 7.9
[32]
HuH.7 HRAS
Mean 3.85
Standard deviation 1.6
Values 3.6 2.4 5.6
[33]
SNU475 HRAS
Mean 11
Standard deviation 0.62
Values 11 11
[34]
THLE HRAS
Mean 10.7
Standard deviation 2.3
Values 9.1 12
[35]
liver HRAS
Mean 2.6
Standard deviation 1.6
Values 4.1 1.1 3.8 1.4
[36]
ref_hepatocyte SPHK1
Mean 11.5
Standard deviation 14
Values 32 4.8 19 1.4 0.27
[37]
HepG2 SPHK1
Mean 75.9
Standard deviation 8.5
Values 82 70
[38]
HepG2.C3A SPHK1
Mean 109
Standard deviation 8.6
Values 1.2e+02 1e+02
[39]
HuH.7 SPHK1
Mean 18.7
Standard deviation 5.5
Values 19 13 24
[40]
SNU475 SPHK1
Mean 4.6
Standard deviation 3.4
Values 2.2 7
[41]
THLE SPHK1
Mean 24.9
Standard deviation 0.21
Values 25 25
[42]
liver SPHK1
Mean 0.512
Standard deviation 0.41
Values 1.1 0.3 0.18 0.46
[43]
ref_hepatocyte KRAS
Mean 8.97
Standard deviation 7.9
Values 18 17 5.4 1.7 2.7
[44]
HepG2 KRAS
Mean 13.9
Standard deviation 3.1
Values 12 16
[45]
HepG2.C3A KRAS
Mean 12.2
Standard deviation 2.3
Values 11 14
[46]
HuH.7 KRAS
Mean 35.4
Standard deviation 4.8
Values 40 30 36
[47]
SNU475 KRAS
Mean 28.7
Standard deviation 5.5
Values 33 25
[48]
THLE KRAS
Mean 25.4
Standard deviation 1.5
Values 24 26
[49]
liver KRAS
Mean 20.4
Standard deviation 8.7
Values 33 16 19 14
[50]
ref_hepatocyte PRKCZ
Mean 7.98
Standard deviation 3.5
Values 14 4.6 6.7 8.2 6.6
[51]
HepG2 PRKCZ
Mean 24.4
Standard deviation 2
Values 26 23
[52]
HepG2.C3A PRKCZ
Mean 28.4
Standard deviation 7.3
Values 33 23
[53]
HuH.7 PRKCZ
Mean 6.79
Standard deviation 1.7
Values 6.1 8.8 5.5
[54]
SNU475 PRKCZ
Mean 2.98
Standard deviation 1.9
Values 4.4 1.6
[55]
THLE PRKCZ
Mean 0.727
Standard deviation 0.035
Values 0.75 0.7
[56]
liver PRKCZ
Mean 3.64
Standard deviation 0.55
Values 2.9 3.9 4.2 3.5
[57]
ref_hepatocyte ITPR2
Mean 5.98
Standard deviation 2.4
Values 7.9 7.6 3.1 3.6 7.6
[58]
HepG2 ITPR2
Mean 24.9
Standard deviation 14
Values 15 35
[59]
HepG2.C3A ITPR2
Mean 60.7
Standard deviation 3.6
Values 63 58
[60]
HuH.7 ITPR2
Mean 20
Standard deviation 7.1
Values 22 26 12
[61]
SNU475 ITPR2
Mean 11
Standard deviation 0.52
Values 11 11
[62]
THLE ITPR2
Mean 13.6
Standard deviation 1.2
Values 14 13
[63]
liver ITPR2
Mean 124
Standard deviation 78
Values 71 2e+02 45 1.8e+02
[64]
ref_hepatocyte SRC
Mean 3.67
Standard deviation 3.6
Values 9.6 4.7 2.2 0.77 1.2
[65]
HepG2 SRC
Mean 66
Standard deviation 21
Values 81 51
[66]
HepG2.C3A SRC
Mean 58.1
Standard deviation 18
Values 71 45
[67]
HuH.7 SRC
Mean 27.9
Standard deviation 2
Values 28 29 26
[68]
SNU475 SRC
Mean 35.6
Standard deviation 3.5
Values 38 33
[69]
THLE SRC
Mean 22.5
Standard deviation 2.7
Values 21 24
[70]
liver SRC
Mean 2.9
Standard deviation 1
Values 4.1 2.5 1.7 3.2
[71]
ref_hepatocyte PRKCD
Mean 3.58
Standard deviation 2
Values 5.9 2.9 5.5 2.1 1.5
[72]
HepG2 PRKCD
Mean 16.9
Standard deviation 3.4
Values 19 15
[73]
HepG2.C3A PRKCD
Mean 17.9
Standard deviation 3.3
Values 20 16
[74]
HuH.7 PRKCD
Mean 12
Standard deviation 0.2
Values 12 12 12
[75]
SNU475 PRKCD
Mean 4.64
Standard deviation 0.32
Values 4.4 4.9
[76]
THLE PRKCD
Mean 11.6
Standard deviation 1.2
Values 11 12
[77]
liver PRKCD
Mean 2.43
Standard deviation 1
Values 3.9 1.4 2.2 2.3
[78]
ref_hepatocyte PDPK1
Mean 3.54
Standard deviation 2
Values 6.9 3.4 3.6 1.8 2
[79]
HepG2 PDPK1
Mean 39.4
Standard deviation 5.6
Values 35 43
[80]
HepG2.C3A PDPK1
Mean 80.1
Standard deviation 13
Values 89 71
[81]
HuH.7 PDPK1
Mean 31.4
Standard deviation 4.5
Values 35 33 26
[82]
SNU475 PDPK1
Mean 17.6
Standard deviation 0.21
Values 17 18
[83]
THLE PDPK1
Mean 25.9
Standard deviation 4.6
Values 23 29
[84]
liver PDPK1
Mean 28.5
Standard deviation 5.1
Values 34 27 22 31
[85]
ref_hepatocyte PLCG1
Mean 3.54
Standard deviation 4.5
Values 11 2.4 1.7 0.91 1.2
[86]
HepG2 PLCG1
Mean 87.8
Standard deviation 4.3
Values 91 85
[87]
HepG2.C3A PLCG1
Mean 60.1
Standard deviation 10
Values 67 53
[88]
HuH.7 PLCG1
Mean 36.2
Standard deviation 5.9
Values 40 30 39
[89]
SNU475 PLCG1
Mean 45.9
Standard deviation 1.9
Values 47 45
[90]
THLE PLCG1
Mean 36.2
Standard deviation 0.92
Values 36 37
[91]
liver PLCG1
Mean 6.36
Standard deviation 4.9
Values 2.3 8.9 2.2 12
[92]
ref_hepatocyte RASA1
Mean 2.68
Standard deviation 1.4
Values 3.2 4.9 1.6 1.4 2.4
[93]
HepG2 RASA1
Mean 7.68
Standard deviation 3
Values 5.6 9.8
[94]
HepG2.C3A RASA1
Mean 12.9
Standard deviation 0.039
Values 13 13
[95]
HuH.7 RASA1
Mean 13.3
Standard deviation 0.87
Values 14 14 12
[96]
SNU475 RASA1
Mean 18.6
Standard deviation 2.3
Values 20 17
[97]
THLE RASA1
Mean 10.8
Standard deviation 0.049
Values 11 11
[98]
liver RASA1
Mean 8.83
Standard deviation 3.2
Values 7.7 13 6.2 8
[99]
ref_hepatocyte PRKCA
Mean 2.45
Standard deviation 2.1
Values 2.7 6 1.1 1.2 1.2
[100]
HepG2 PRKCA
Mean 38.7
Standard deviation 5.6
Values 35 43
[101]
HepG2.C3A PRKCA
Mean 35.5
Standard deviation 4.5
Values 32 39
[102]
HuH.7 PRKCA
Mean 43.7
Standard deviation 11
Values 54 44 33
[103]
SNU475 PRKCA
Mean 20
Standard deviation 4.3
Values 17 23
[104]
THLE PRKCA
Mean 28.8
Standard deviation 11
Values 21 36
[105]
liver PRKCA
Mean 13.2
Standard deviation 7.1
Values 11 17 4.7 21
[106]
ref_hepatocyte ITPR3
Mean 2.22
Standard deviation 2.4
Values 5.9 2.9 2.1 0.078 0.19
[107]
HepG2 ITPR3
Mean 192
Standard deviation 90
Values 2.6e+02 1.3e+02
[108]
HepG2.C3A ITPR3
Mean 77
Standard deviation 9.2
Values 83 70
[109]
HuH.7 ITPR3
Mean 25.8
Standard deviation 6.8
Values 34 20 24
[110]
SNU475 ITPR3
Mean 20.8
Standard deviation 0.27
Values 21 21
[111]
THLE ITPR3
Mean 105
Standard deviation 12
Values 96 1.1e+02
[112]
liver ITPR3
Mean 3.69
Standard deviation 1.7
Values 2.7 4.1 2 5.9
[113]
ref_hepatocyte ITPR1
Mean 0.398
Standard deviation 0.44
Values 1.2 0.25 0.1 0.2 0.25
[114]
HepG2 ITPR1
Mean 7.73
Standard deviation 1.3
Values 8.7 6.8
[115]
HepG2.C3A ITPR1
Mean 6.36
Standard deviation 0.83
Values 7 5.8
[116]
HuH.7 ITPR1
Mean 13.6
Standard deviation 3.5
Values 15 16 9.6
[117]
SNU475 ITPR1
Mean 5.27
Standard deviation 3.4
Values 2.8 7.7
[118]
THLE ITPR1
Mean 10.8
Standard deviation 2.1
Values 12 9.3
[119]
liver ITPR1
Mean 14.2
Standard deviation 12
Values 4.3 20 3.8 29
[120]
ref_hepatocyte KDR
Mean 0.384
Standard deviation 0.38
Values 0.021 0.075 0.38 0.47 0.98
[121]
HepG2 KDR
Mean 0.0172
Standard deviation 2.3e-05
Values 0.017 0.017
[122]
HepG2.C3A KDR
Mean 0.00486
Standard deviation 0.0069
Values 0.0097 0
[123]
HuH.7 KDR
Mean 0.00761
Standard deviation 0.0083
Values 0.016 0.0064 0
[124]
SNU475 KDR
Mean 0.211
Standard deviation 0.25
Values 0.037 0.39
[125]
THLE KDR
Mean 20.9
Standard deviation 3.6
Values 18 23
[126]
liver KDR
Mean 42.9
Standard deviation 25
Values 17 76 45 33
[127]
ref_hepatocyte PRKCB
Mean 0.255
Standard deviation 0.29
Values 0 0 0.4 0.2 0.67
[128]
HepG2 PRKCB
Mean 0.00501
Standard deviation 0.001
Values 0.0057 0.0043
[129]
HepG2.C3A PRKCB
Mean 0.0102
Standard deviation 0.00071
Values 0.0097 0.011
[130]
HuH.7 PRKCB
Mean 0
Standard deviation 0
Values 0 0 0
[131]
SNU475 PRKCB
Mean 2.62
Standard deviation 2.8
Values 0.61 4.6
[132]
THLE PRKCB
Mean 0.0742
Standard deviation 0.037
Values 0.1 0.048
[133]
liver PRKCB
Mean 4.2
Standard deviation 2.1
Values 2.7 6.8 2.2 5