REACTOME_VASOPRESSIN_REGULATES_RENAL_WATER_HOMEOSTASIS_VIA_AQUAPORINS | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | GNAS | Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas | 0.42[1] | 0.45[2] | 0.12[3] | 0.52[4] | -0.05[5] | -1.08[6] | |
2 | GNG5 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 | -1.21[7] | -1.04[8] | -1.89[9] | -2.14[10] | -2.20[11] | -1.33[12] | |
3 | PRKAR1A | cAMP-dependent protein kinase type I-alpha regulatory subunit | [13] | 0.07[14] | 0.18[15] | 0.35[16] | -0.42[17] | -0.33[18] | 0.84[19] |
4 | GNB1 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | [20] | 1.01[21] | 1.01[22] | 0.55[23] | 0.96[24] | 0.94[25] | -0.98[26] |
5 | GNB2 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 | [27] | -0.61[28] | -0.87[29] | -0.51[30] | -0.69[31] | -0.44[32] | -1.35[33] |
6 | AQP3 | Aquaporin-3 | [34] | -2.69[35] | -6.02[36] | -5.06[37] | -6.58[38] | -7.26[39] | 0.00[40] |
7 | GNG10 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10 | -4.71[41] | -4.43[42] | -4.71[43] | -4.14[44] | -3.13[45] | -4.09[46] | |
8 | GNG12 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 | -4.76[47] | -7.70[48] | 0.27[49] | 1.55[50] | 1.84[51] | 0.74[52] | |
9 | PRKACA | cAMP-dependent protein kinase catalytic subunit alpha | [53] | -0.17[54] | -0.36[55] | -0.34[56] | -0.80[57] | -0.01[58] | -0.53[59] |
10 | RAB11A | Ras-related protein Rab-11A | [60] | 0.68[61] | 1.04[62] | 1.65[63] | 0.66[64] | 0.87[65] | 0.62[66] |
11 | PRKAR2A | cAMP-dependent protein kinase type II-alpha regulatory subunit | [67] | 0.04[68] | -0.28[69] | 0.84[70] | -0.61[71] | -0.56[72] | 0.40[73] |
12 | PRKAR1B | cAMP-dependent protein kinase type I-beta regulatory subunit | [74] | 0.97[75] | 0.41[76] | -1.36[77] | -4.42[78] | -1.44[79] | 0.08[80] |
13 | MYO5B | Unconventional myosin-Vb | [81] | 1.15[82] | 1.69[83] | -0.84[84] | -0.18[85] | -2.19[86] | 2.10[87] |
14 | GNB5 | Guanine nucleotide-binding protein subunit beta-5 | [88] | 0.09[89] | 0.12[90] | 1.16[91] | 0.46[92] | 0.77[93] | 1.14[94] |
15 | PRKACB | cAMP-dependent protein kinase catalytic subunit beta | [95] | -0.84[96] | -0.07[97] | 1.23[98] | 1.91[99] | 0.96[100] | 1.96[101] |
16 | ADCY9 | Adenylate cyclase type 9 | [102] | 2.61[103] | 1.79[104] | 2.24[105] | 0.63[106] | 0.37[107] | 2.67[108] |
17 | ADCY6 | Adenylate cyclase type 6 | [109] | 2.04[110] | 2.50[111] | 2.48[112] | 2.18[113] | 3.04[114] | 2.89[115] |
18 | GNG11 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 | -8.19[116] | -8.20[117] | -7.49[118] | 1.94[119] | 3.45[120] | 2.49[121] | |
19 | RAB11FIP | Rab11 family-interacting protein 2 | [122] | 0.50[123] | 1.80[124] | 1.09[125] | 1.08[126] | 1.65[127] | 2.31[128] |
20 | GNG7 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 | 1.55[129] | 1.19[130] | 2.01[131] | -2.56[132] | -1.75[133] | 0.28[134] | |
21 | ADCY1 | Adenylate cyclase type 1 | [135] | -0.84[136] | -2.72[137] | -2.90[138] | -2.44[139] | -2.26[140] | 5.25[141] |
22 | GNG4 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 | 3.46[142] | 1.22[143] | 5.04[144] | 0.93[145] | -0.99[146] | -2.30[147] | |
23 | ADCY7 | Adenylate cyclase type 7 | [148] | 3.50[149] | 3.12[150] | 2.09[151] | 2.98[152] | 2.65[153] | 3.18[154] |
24 | GNB4 | Guanine nucleotide-binding protein subunit beta-4 | [155] | -0.38[156] | 0.11[157] | 1.13[158] | 2.35[159] | 5.28[160] | 4.34[161] |
25 | GNG2 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | -6.29[162] | -7.17[163] | [164] | 2.79[165] | 2.46[166] | 3.03[167] | |
26 | AQP1 | Aquaporin-1 | [168] | -4.76[169] | [170] | -1.82[171] | 2.28[172] | -1.96[173] | 4.65[174] |
27 | AVP | Vasopressin-neurophysin 2-copeptin | [175] | -4.07[176] | -1.63[177] | -2.04[178] | [179] | -7.69[180] | -0.81[181] |
28 | GNGT2 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 | [182] | [183] | [184] | -2.39[185] | -6.87[186] | 0.36[187] | |
29 | GNG3 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 | -0.86[188] | 0.96[189] | -1.25[190] | -1.03[191] | -1.15[192] | 0.17[193] | |
30 | PRKAR2B | cAMP-dependent protein kinase type II-beta regulatory subunit | [194] | -2.35[195] | -0.53[196] | 3.77[197] | 4.76[198] | 3.46[199] | 3.57[200] |
31 | ADCY3 | Adenylate cyclase type 3 | [201] | 1.45[202] | 0.20[203] | 3.54[204] | 4.41[205] | 6.13[206] | 3.77[207] |
32 | ADCY2 | Adenylate cyclase type 2 | [208] | -5.39[209] | -3.47[210] | -4.70[211] | -3.06[212] | -3.99[213] | -3.87[214] |
33 | AQP4 | Aquaporin-4 | [215] | -0.23[216] | 1.38[217] | 4.00[218] | -4.31[219] | -5.71[220] | 1.59[221] |
34 | GNB3 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 | [222] | 1.58[223] | 3.83[224] | 3.14[225] | 0.68[226] | 3.59[227] | -1.43[228] |
35 | ADCY5 | Adenylate cyclase type 5 | [229] | 0.14[230] | 1.13[231] | 2.18[232] | 0.32[233] | 1.64[234] | 6.63[235] |
36 | AVPR2 | Vasopressin V2 receptor | [236] | 0.01[237] | 0.38[238] | -3.92[239] | 0.05[240] | -2.72[241] | 2.40[242] |
37 | ADCY4 | Adenylate cyclase type 4 | [243] | 0.08[244] | -1.00[245] | 1.66[246] | [247] | [248] | 8.62[249] |
38 | GNGT1 | Guanine nucleotide-binding protein G(T) subunit gamma-T1 | [250] | [251] | [252] | [253] | [254] | [255] | [256] |
39 | PRKACG | cAMP-dependent protein kinase catalytic subunit gamma | [257] | [258] | [259] | [260] | [261] | [262] | [263] |
40 | AQP2 | Aquaporin-2 | [264] | [265] | [266] | [267] | [268] | [269] | [270] |
41 | GNG8 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8 | [271] | [272] | [273] | [274] | [275] | [276] | |
42 | ADCY8 | Adenylate cyclase type 8 | [277] | [278] | [279] | [280] | [281] | [282] | [283] |
43 | GNG13 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 | [284] | [285] | [286] | [287] | [288] | [289] |