REACTOME_UNWINDING_OF_DNA Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 MCM7 DNA replication licensing factor MCM7 [1] -0.01[2] -0.07[3] 0.42[4] -0.18[5] -0.32[6] 0.29[7]
2 MCM3 DNA replication licensing factor MCM3 [8] 0.37[9] 0.38[10] -0.25[11] -0.49[12] -0.09[13] 0.41[14]
3 MCM4 DNA replication licensing factor MCM4 [15] 0.14[16] 0.18[17] 0.16[18] 0.53[19] 0.48[20] 0.11[21]
4 MCM5 DNA replication licensing factor MCM5 [22] -0.71[23] -0.69[24] -0.80[25] -0.95[26] -0.72[27] 0.17[28]
5 GINS2 DNA replication complex GINS protein PSF2 [29] -1.32[30] -0.87[31] -1.88[32] -1.99[33] -1.70[34] -2.21[35]
6 MCM6 DNA replication licensing factor MCM6 [36] -0.73[37] -0.86[38] 0.42[39] 0.95[40] 1.05[41] -0.20[42]
7 MCM2 DNA replication licensing factor MCM2 [43] 1.00[44] 0.60[45] 1.16[46] 0.66[47] 0.98[48] -0.53[49]
8 CDC45 Cell division control protein 45 homolog [50] -0.73[51] -0.62[52] -0.70[53] -0.21[54] -0.57[55] -1.82[56]
9 GINS1 DNA replication complex GINS protein PSF1 [57] 0.28[58] 0.33[59] -0.22[60] 0.83[61] -0.55[62] -1.54[63]
10 GINS3 DNA replication complex GINS protein PSF3 [64] -0.77[65] -1.42[66] -2.37[67] -0.73[68] -0.22[69] -0.98[70]
11 MCM8 DNA helicase MCM8 [71] 0.27[72] 1.14[73] -0.32[74] 1.13[75] -0.01[76] 0.72[77]
12 GINS4 DNA replication complex GINS protein SLD5 [78] 0.56[79] 0.60[80] 0.71[81] 0.31[82] 0.19[83] 0.15[84]
[1]
ref_hepatocyte MCM7
Mean 13.4
Standard deviation 7.2
Values 15 25 12 8.9 6.7
[2]
HepG2 MCM7
Mean 112
Standard deviation 0.92
Values 1.1e+02 1.1e+02
[3]
HepG2.C3A MCM7
Mean 86.1
Standard deviation 36
Values 61 1.1e+02
[4]
HuH.7 MCM7
Mean 194
Standard deviation 1.1e+02
Values 2.4e+02 70 2.7e+02
[5]
SNU475 MCM7
Mean 60
Standard deviation 16
Values 49 71
[6]
THLE MCM7
Mean 99
Standard deviation 18
Values 86 1.1e+02
[7]
liver MCM7
Mean 10.9
Standard deviation 2.3
Values 13 8.8 13 9.1
[8]
ref_hepatocyte MCM3
Mean 13
Standard deviation 10
Values 30 15 7.4 7.5 5.1
[9]
HepG2 MCM3
Mean 141
Standard deviation 33
Values 1.2e+02 1.6e+02
[10]
HepG2.C3A MCM3
Mean 113
Standard deviation 52
Values 76 1.5e+02
[11]
HuH.7 MCM3
Mean 117
Standard deviation 69
Values 1.5e+02 38 1.6e+02
[12]
SNU475 MCM3
Mean 47
Standard deviation 14
Values 37 57
[13]
THLE MCM3
Mean 112
Standard deviation 21
Values 97 1.3e+02
[14]
liver MCM3
Mean 11.4
Standard deviation 4
Values 10 12 17 7.2
[15]
ref_hepatocyte MCM4
Mean 9.18
Standard deviation 8.6
Values 21 15 5.1 2.3 1.9
[16]
HepG2 MCM4
Mean 84.7
Standard deviation 28
Values 65 1e+02
[17]
HepG2.C3A MCM4
Mean 69.6
Standard deviation 44
Values 39 1e+02
[18]
HuH.7 MCM4
Mean 110
Standard deviation 72
Values 1.6e+02 27 1.5e+02
[19]
SNU475 MCM4
Mean 67.3
Standard deviation 15
Values 57 78
[20]
THLE MCM4
Mean 118
Standard deviation 29
Values 98 1.4e+02
[21]
liver MCM4
Mean 6.6
Standard deviation 2.7
Values 4.8 8.8 9 3.8
[22]
ref_hepatocyte MCM5
Mean 8.67
Standard deviation 4.6
Values 8.3 17 7.2 6.4 4.9
[23]
HepG2 MCM5
Mean 44.4
Standard deviation 5.9
Values 40 49
[24]
HepG2.C3A MCM5
Mean 36.1
Standard deviation 17
Values 24 48
[25]
HuH.7 MCM5
Mean 53.6
Standard deviation 30
Values 74 20 67
[26]
SNU475 MCM5
Mean 22.8
Standard deviation 3.6
Values 20 25
[27]
THLE MCM5
Mean 48.5
Standard deviation 18
Values 36 61
[28]
liver MCM5
Mean 6.52
Standard deviation 2.3
Values 4.8 8.4 8.7 4.2
[29]
ref_hepatocyte GINS2
Mean 5.23
Standard deviation 4.1
Values 11 8.6 1.5 2.9 2.4
[30]
HepG2 GINS2
Mean 17.6
Standard deviation 7
Values 13 23
[31]
HepG2.C3A GINS2
Mean 19.2
Standard deviation 14
Values 9.3 29
[32]
HuH.7 GINS2
Mean 15.3
Standard deviation 10
Values 19 3.9 23
[33]
SNU475 GINS2
Mean 6.67
Standard deviation 0.79
Values 6.1 7.2
[34]
THLE GINS2
Mean 14.9
Standard deviation 1.9
Values 14 16
[35]
liver GINS2
Mean 0.753
Standard deviation 0.55
Values 0.68 0.47 1.5 0.32
[36]
ref_hepatocyte MCM6
Mean 4.29
Standard deviation 3.5
Values 3.7 10 4.3 1.8 1.5
[37]
HepG2 MCM6
Mean 21.7
Standard deviation 9.4
Values 15 28
[38]
HepG2.C3A MCM6
Mean 15.9
Standard deviation 9.1
Values 9.5 22
[39]
HuH.7 MCM6
Mean 61.7
Standard deviation 38
Values 84 18 83
[40]
SNU475 MCM6
Mean 42.1
Standard deviation 6.7
Values 37 47
[41]
THLE MCM6
Mean 81.8
Standard deviation 9.3
Values 75 88
[42]
liver MCM6
Mean 2.49
Standard deviation 1
Values 1.7 3.7 2.9 1.6
[43]
ref_hepatocyte MCM2
Mean 4.21
Standard deviation 3.2
Values 9.4 4.9 3.2 1.5 2.1
[44]
HepG2 MCM2
Mean 70.6
Standard deviation 14
Values 61 81
[45]
HepG2.C3A MCM2
Mean 42.9
Standard deviation 17
Values 31 55
[46]
HuH.7 MCM2
Mean 101
Standard deviation 57
Values 1.4e+02 36 1.3e+02
[47]
SNU475 MCM2
Mean 33.8
Standard deviation 11
Values 26 42
[48]
THLE MCM2
Mean 76.3
Standard deviation 20
Values 62 91
[49]
liver MCM2
Mean 1.95
Standard deviation 1.4
Values 1.1 4 1.8 0.94
[50]
ref_hepatocyte CDC45
Mean 2.51
Standard deviation 2.5
Values 3.1 6.6 1.3 1.1 0.37
[51]
HepG2 CDC45
Mean 12.8
Standard deviation 2.7
Values 11 15
[52]
HepG2.C3A CDC45
Mean 11
Standard deviation 7.8
Values 5.4 17
[53]
HuH.7 CDC45
Mean 16.7
Standard deviation 12
Values 20 3.6 26
[54]
SNU475 CDC45
Mean 11
Standard deviation 3.8
Values 8.4 14
[55]
THLE CDC45
Mean 15.7
Standard deviation 2.2
Values 14 17
[56]
liver CDC45
Mean 0.476
Standard deviation 0.53
Values 0.16 0.56 1.2 0
[57]
ref_hepatocyte GINS1
Mean 2.41
Standard deviation 3.2
Values 7.9 2.7 0.3 0.7 0.43
[58]
HepG2 GINS1
Mean 24.5
Standard deviation 5.7
Values 20 28
[59]
HepG2.C3A GINS1
Mean 20.3
Standard deviation 15
Values 10 31
[60]
HuH.7 GINS1
Mean 22.2
Standard deviation 13
Values 29 7.7 30
[61]
SNU475 GINS1
Mean 21.8
Standard deviation 2.5
Values 20 24
[62]
THLE GINS1
Mean 15.1
Standard deviation 5
Values 12 19
[63]
liver GINS1
Mean 0.553
Standard deviation 0.34
Values 0.21 0.88 0.8 0.32
[64]
ref_hepatocyte GINS3
Mean 1.92
Standard deviation 1
Values 3.4 2.4 2 1.1 0.81
[65]
HepG2 GINS3
Mean 9.44
Standard deviation 1.8
Values 8.1 11
[66]
HepG2.C3A GINS3
Mean 4.82
Standard deviation 3
Values 2.7 6.9
[67]
HuH.7 GINS3
Mean 4
Standard deviation 2
Values 4.7 1.8 5.5
[68]
SNU475 GINS3
Mean 5.88
Standard deviation 0.89
Values 5.2 6.5
[69]
THLE GINS3
Mean 15.2
Standard deviation 2.6
Values 13 17
[70]
liver GINS3
Mean 0.651
Standard deviation 0.37
Values 0.52 0.46 1.2 0.42
[71]
ref_hepatocyte MCM8
Mean 1.68
Standard deviation 1.7
Values 3.8 3.2 0.45 0.49 0.46
[72]
HepG2 MCM8
Mean 16.9
Standard deviation 9.8
Values 10 24
[73]
HepG2.C3A MCM8
Mean 24.7
Standard deviation 16
Values 14 36
[74]
HuH.7 MCM8
Mean 14.5
Standard deviation 7.7
Values 22 6.3 15
[75]
SNU475 MCM8
Mean 18.7
Standard deviation 3.3
Values 16 21
[76]
THLE MCM8
Mean 15.3
Standard deviation 1.1
Values 15 16
[77]
liver MCM8
Mean 1.84
Standard deviation 1.3
Values 0.8 3.4 0.82 2.3
[78]
ref_hepatocyte GINS4
Mean 0.782
Standard deviation 0.75
Values 1.9 1.2 0.48 0.15 0.19
[79]
HepG2 GINS4
Mean 9.67
Standard deviation 3
Values 7.6 12
[80]
HepG2.C3A GINS4
Mean 7.98
Standard deviation 5.2
Values 4.3 12
[81]
HuH.7 GINS4
Mean 13.8
Standard deviation 7.9
Values 19 4.7 18
[82]
SNU475 GINS4
Mean 4.95
Standard deviation 1.7
Values 3.8 6.1
[83]
THLE GINS4
Mean 8.25
Standard deviation 0.73
Values 7.7 8.8
[84]
liver GINS4
Mean 0.576
Standard deviation 0.18
Values 0.45 0.61 0.82 0.42