REACTOME_BLOOD_GROUP_SYSTEMS_BIOSYNTHESIS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 ST6GALNAC6 Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 [1] -0.03[2] -0.12[3] 0.20[4] -0.04[5] -0.09[6] -0.07[7]
2 ST3GAL6 Type 2 lactosamine alpha-2,3-sialyltransferase [8] -1.93[9] -0.92[10] 0.15[11] -6.43[12] -1.06[13] 0.16[14]
3 ST3GAL4 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 -0.37[15] -1.60[16] -3.44[17] 0.90[18] 0.49[19] -1.58[20]
4 ST3GAL3 CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase 0.30[21] -0.22[22] 0.06[23] 0.07[24] 0.82[25] -0.81[26]
5 FUT6 Alpha-(1,3)-fucosyltransferase 6 [27] 1.64[28] 2.56[29] -1.90[30] -4.60[31] -4.51[32] 1.00[33]
6 FUT10 Alpha-(1,3)-fucosyltransferase 10 [34] 1.34[35] 0.55[36] 1.21[37] -0.28[38] 0.20[39] 0.12[40]
7 FUT11 Alpha-(1,3)-fucosyltransferase 11 [41] 2.65[42] 1.87[43] 0.09[44] 1.89[45] 2.24[46] 1.41[47]
8 FUT4 Alpha-(1,3)-fucosyltransferase 4 [48] 0.14[49] -0.77[50] -2.40[51] 1.54[52] 1.74[53] 0.95[54]
9 RHCE Blood group Rh(CE) polypeptide [55] -3.50[56] -2.84[57] -1.61[58] -2.66[59] -1.54[60] -2.12[61]
10 FUT2 Galactoside 2-alpha-L-fucosyltransferase 2 [62] -0.32[63] 1.64[64] 0.37[65] -0.26[66] -0.57[67] -0.72[68]
11 FUT3 Galactoside 3(4)-L-fucosyltransferase [69] -0.57[70] 0.56[71] 1.91[72] -5.49[73] -3.84[74] -2.02[75]
12 FUT1 Galactoside 2-alpha-L-fucosyltransferase 1 [76] 1.40[77] 0.42[78] 2.26[79] -0.94[80] 0.64[81] 1.03[82]
13 RHD Blood group Rh(D) polypeptide [83] -1.73[84] -0.19[85] -0.99[86] -0.45[87] -0.84[88] 0.72[89]
14 B3GALT4 Beta-1,3-galactosyltransferase 4 [90] -4.10[91] -4.46[92] -0.93[93] -4.07[94] 2.10[95] 1.87[96]
15 B3GALT5 Beta-1,3-galactosyltransferase 5 [97] 0.50[98] [99] -5.76[100] 0.42[101] [102] -0.13[103]
16 B4GALNT2 Beta-1,4 N-acetylgalactosaminyltransferase 2 [104] 2.89[105] [106] 4.07[107] -3.39[108] -4.11[109] [110]
17 FUT7 Alpha-(1,3)-fucosyltransferase 7 [111] 3.82[112] 2.64[113] -5.01[114] -4.25[115] -3.04[116] 0.62[117]
18 B3GALT2 Beta-1,3-galactosyltransferase 2 [118] [119] -0.56[120] 4.51[121] 9.32[122] 1.32[123] 6.64[124]
19 FUT9 Alpha-(1,3)-fucosyltransferase 9 [125] 1.44[126] 1.62[127] 1.69[128] 2.43[129] 2.52[130] 2.38[131]
20 FUT5 Alpha-(1,3)-fucosyltransferase 5 [132] [133] [134] [135] [136] [137] [138]
21 B3GALT1 Beta-1,3-galactosyltransferase 1 [139] [140] [141] [142] [143] [144] [145]
[1]
ref_hepatocyte ST6GALNAC6
Mean 11.4
Standard deviation 11
Values 2 3.3 5.3 23 23
[2]
HepG2 ST6GALNAC6
Mean 18.6
Standard deviation 5.7
Values 23 15
[3]
HepG2.C3A ST6GALNAC6
Mean 26.4
Standard deviation 11
Values 34 18
[4]
HuH.7 ST6GALNAC6
Mean 28.5
Standard deviation 1.3
Values 28 30 28
[5]
SNU475 ST6GALNAC6
Mean 16.9
Standard deviation 2.2
Values 18 15
[6]
THLE ST6GALNAC6
Mean 15.8
Standard deviation 1.9
Values 14 17
[7]
liver ST6GALNAC6
Mean 21.6
Standard deviation 12
Values 23 14 39 11
[8]
ref_hepatocyte ST3GAL6
Mean 10.6
Standard deviation 7.2
Values 10 6.7 1 16 19
[9]
HepG2 ST3GAL6
Mean 4.65
Standard deviation 0.55
Values 4.3 5
[10]
HepG2.C3A ST3GAL6
Mean 14
Standard deviation 2
Values 15 13
[11]
HuH.7 ST3GAL6
Mean 25.5
Standard deviation 5.8
Values 29 19 29
[12]
SNU475 ST3GAL6
Mean 0.188
Standard deviation 0.12
Values 0.1 0.27
[13]
THLE ST3GAL6
Mean 7.43
Standard deviation 1.1
Values 6.7 8.2
[14]
liver ST3GAL6
Mean 23.4
Standard deviation 8.2
Values 33 15 18 28
[15]
ref_hepatocyte ST3GAL4
Mean 6.03
Standard deviation 3.2
Values 2.5 9.8 5.5 8.8 3.5
[16]
HepG2 ST3GAL4
Mean 7.77
Standard deviation 0.82
Values 8.3 7.2
[17]
HepG2.C3A ST3GAL4
Mean 4.98
Standard deviation 0.18
Values 4.9 5.1
[18]
HuH.7 ST3GAL4
Mean 1.21
Standard deviation 0.13
Values 1.3 1.2 1.1
[19]
SNU475 ST3GAL4
Mean 17.1
Standard deviation 3
Values 15 19
[20]
THLE ST3GAL4
Mean 12.4
Standard deviation 0.71
Values 12 13
[21]
liver ST3GAL4
Mean 3.98
Standard deviation 1.1
Values 3.7 4 2.8 5.4
[22]
ref_hepatocyte ST3GAL3
Mean 2.23
Standard deviation 1
Values 2.5 0.54 2.3 2.6 3.2
[23]
HepG2 ST3GAL3
Mean 4.58
Standard deviation 1.4
Values 5.5 3.6
[24]
HepG2.C3A ST3GAL3
Mean 4.78
Standard deviation 2.4
Values 6.5 3.1
[25]
HuH.7 ST3GAL3
Mean 5.06
Standard deviation 0.7
Values 5.6 4.3 5.3
[26]
SNU475 ST3GAL3
Mean 3.56
Standard deviation 0.78
Values 4.1 3
[27]
THLE ST3GAL3
Mean 5.76
Standard deviation 0.51
Values 5.4 6.1
[28]
liver ST3GAL3
Mean 2.51
Standard deviation 0.3
Values 2.9 2.4 2.5 2.2
[29]
ref_hepatocyte FUT6
Mean 1.55
Standard deviation 1.2
Values 2.3 0.4 0.15 2.1 2.8
[30]
HepG2 FUT6
Mean 8.07
Standard deviation 0.59
Values 7.7 8.5
[31]
HepG2.C3A FUT6
Mean 22.8
Standard deviation 6.5
Values 27 18
[32]
HuH.7 FUT6
Mean 0.906
Standard deviation 0.57
Values 0.54 1.6 0.62
[33]
SNU475 FUT6
Mean 0.0975
Standard deviation 0.02
Values 0.083 0.11
[34]
THLE FUT6
Mean 0.0997
Standard deviation 0.043
Values 0.13 0.069
[35]
liver FUT6
Mean 6.13
Standard deviation 5.5
Values 14 2.4 4.9 3.1
[36]
ref_hepatocyte FUT10
Mean 1.18
Standard deviation 0.99
Values 2.8 1.1 1.3 0.47 0.29
[37]
HepG2 FUT10
Mean 5.01
Standard deviation 1.2
Values 4.2 5.9
[38]
HepG2.C3A FUT10
Mean 4.34
Standard deviation 1.6
Values 3.2 5.4
[39]
HuH.7 FUT10
Mean 5.96
Standard deviation 1.8
Values 7.6 6.3 4
[40]
SNU475 FUT10
Mean 1.48
Standard deviation 0.21
Values 1.6 1.3
[41]
THLE FUT10
Mean 1.99
Standard deviation 0.04
Values 2 2
[42]
liver FUT10
Mean 2.54
Standard deviation 1.1
Values 1.5 3.9 1.8 3
[43]
ref_hepatocyte FUT11
Mean 0.657
Standard deviation 0.41
Values 0.74 0.91 1.1 0.34 0.15
[44]
HepG2 FUT11
Mean 6.9
Standard deviation 1.9
Values 5.5 8.2
[45]
HepG2.C3A FUT11
Mean 6.01
Standard deviation 0.16
Values 5.9 6.1
[46]
HuH.7 FUT11
Mean 1.53
Standard deviation 0.33
Values 1.4 1.9 1.2
[47]
SNU475 FUT11
Mean 3.72
Standard deviation 0.55
Values 4.1 3.3
[48]
THLE FUT11
Mean 4.54
Standard deviation 0.93
Values 3.9 5.2
[49]
liver FUT11
Mean 3.44
Standard deviation 2.3
Values 0.89 5.9 2.2 4.8
[50]
ref_hepatocyte FUT4
Mean 0.513
Standard deviation 0.16
Values 0.39 0.7 0.67 0.45 0.36
[51]
HepG2 FUT4
Mean 0.944
Standard deviation 0.13
Values 0.85 1
[52]
HepG2.C3A FUT4
Mean 0.751
Standard deviation 0.18
Values 0.62 0.88
[53]
HuH.7 FUT4
Mean 0.212
Standard deviation 0.071
Values 0.21 0.28 0.14
[54]
SNU475 FUT4
Mean 2.28
Standard deviation 0.35
Values 2.5 2
[55]
THLE FUT4
Mean 2.51
Standard deviation 0.19
Values 2.4 2.6
[56]
liver FUT4
Mean 1.95
Standard deviation 0.7
Values 1.6 2.4 1.2 2.7
[57]
ref_hepatocyte RHCE
Mean 0.455
Standard deviation 0.58
Values 0 0.1 0.43 0.29 1.5
[58]
HepG2 RHCE
Mean 0.0673
Standard deviation 0.035
Values 0.092 0.043
[59]
HepG2.C3A RHCE
Mean 0.159
Standard deviation 0.12
Values 0.24 0.075
[60]
HuH.7 RHCE
Mean 0.326
Standard deviation 0.12
Values 0.22 0.46 0.3
[61]
SNU475 RHCE
Mean 0.11
Standard deviation 0.055
Values 0.15 0.071
[62]
THLE RHCE
Mean 0.23
Standard deviation 0.077
Values 0.28 0.18
[63]
liver RHCE
Mean 0.207
Standard deviation 0.1
Values 0.094 0.17 0.23 0.33
[64]
ref_hepatocyte FUT2
Mean 0.363
Standard deviation 0.27
Values 0.096 0.67 0.63 0.13 0.29
[65]
HepG2 FUT2
Mean 0.487
Standard deviation 0.064
Values 0.44 0.53
[66]
HepG2.C3A FUT2
Mean 2.82
Standard deviation 0.31
Values 3 2.6
[67]
HuH.7 FUT2
Mean 1.02
Standard deviation 0.19
Values 1.2 0.83 1
[68]
SNU475 FUT2
Mean 0.463
Standard deviation 0.012
Values 0.45 0.47
[69]
THLE FUT2
Mean 0.36
Standard deviation 0.11
Values 0.44 0.28
[70]
liver FUT2
Mean 0.435
Standard deviation 0.31
Values 0.12 0.74 0.23 0.65
[71]
ref_hepatocyte FUT3
Mean 0.287
Standard deviation 0.49
Values 1.2 0 0 0.22 0.065
[72]
HepG2 FUT3
Mean 0.323
Standard deviation 0.11
Values 0.4 0.24
[73]
HepG2.C3A FUT3
Mean 1.06
Standard deviation 0.81
Values 1.6 0.48
[74]
HuH.7 FUT3
Mean 2.35
Standard deviation 2.7
Values 0.66 5.4 0.96
[75]
SNU475 FUT3
Mean 0.00971
Standard deviation 0.00061
Values 0.0093 0.01
[76]
THLE FUT3
Mean 0.0293
Standard deviation 0.034
Values 0.053 0.0053
[77]
liver FUT3
Mean 0.139
Standard deviation 0.11
Values 0.28 0.014 0.1 0.16
[78]
ref_hepatocyte FUT1
Mean 0.279
Standard deviation 0.21
Values 0.61 0.17 0.12 0.37 0.12
[79]
HepG2 FUT1
Mean 1.23
Standard deviation 1.4
Values 2.2 0.22
[80]
HepG2.C3A FUT1
Mean 0.932
Standard deviation 0.76
Values 1.5 0.4
[81]
HuH.7 FUT1
Mean 2.9
Standard deviation 0.98
Values 2.2 4 2.5
[82]
SNU475 FUT1
Mean 0.222
Standard deviation 0.034
Values 0.25 0.2
[83]
THLE FUT1
Mean 0.638
Standard deviation 0.12
Values 0.72 0.55
[84]
liver FUT1
Mean 1.13
Standard deviation 0.27
Values 1.4 0.83 0.98 1.3
[85]
ref_hepatocyte RHD
Mean 0.212
Standard deviation 0.13
Values 0.14 0.065 0.32 0.16 0.37
[86]
HepG2 RHD
Mean 0.107
Standard deviation 0.037
Values 0.08 0.13
[87]
HepG2.C3A RHD
Mean 0.465
Standard deviation 0.13
Values 0.55 0.38
[88]
HuH.7 RHD
Mean 0.233
Standard deviation 0.093
Values 0.18 0.34 0.18
[89]
SNU475 RHD
Mean 0.235
Standard deviation 0.018
Values 0.22 0.25
[90]
THLE RHD
Mean 0.173
Standard deviation 0.057
Values 0.21 0.13
[91]
liver RHD
Mean 0.691
Standard deviation 0.047
Values 0.68 0.68 0.64 0.75
[92]
ref_hepatocyte B3GALT4
Mean 0.133
Standard deviation 0.25
Values 0 0 0 0.086 0.58
[93]
HepG2 B3GALT4
Mean 0.0129
Standard deviation 0.0061
Values 0.017 0.0086
[94]
HepG2.C3A B3GALT4
Mean 0.0151
Standard deviation 0.0062
Values 0.019 0.011
[95]
HuH.7 B3GALT4
Mean 0.151
Standard deviation 0.047
Values 0.2 0.15 0.1
[96]
SNU475 B3GALT4
Mean 0.012
Standard deviation 0.0027
Values 0.014 0.01
[97]
THLE B3GALT4
Mean 0.836
Standard deviation 0.11
Values 0.91 0.76
[98]
liver B3GALT4
Mean 0.961
Standard deviation 0.76
Values 2.1 0.4 0.85 0.53
[99]
ref_hepatocyte B3GALT5
Mean 0.0682
Standard deviation 0.13
Values 0.045 0 0.3 0 0
[100]
HepG2 B3GALT5
Mean 0.16
Standard deviation 0.15
Values 0.27 0.051
[101]
HepG2.C3A B3GALT5
Mean 0
Standard deviation 0
Values 0 0
[102]
HuH.7 B3GALT5
Mean 0.00273
Standard deviation 0.0047
Values 0.0082 0 0
[103]
SNU475 B3GALT5
Mean 0.139
Standard deviation 0.098
Values 0.07 0.21
[104]
THLE B3GALT5
Mean 0
Standard deviation 0
Values 0 0
[105]
liver B3GALT5
Mean 0.123
Standard deviation 0.083
Values 0.14 0.1 0.026 0.23
[106]
ref_hepatocyte B4GALNT2
Mean 0.0348
Standard deviation 0.078
Values 0.17 0 0 0 0
[107]
HepG2 B4GALNT2
Mean 0.43
Standard deviation 0.0077
Values 0.44 0.42
[108]
HepG2.C3A B4GALNT2
Mean 0
Standard deviation 0
Values 0 0
[109]
HuH.7 B4GALNT2
Mean 1.27
Standard deviation 0.14
Values 1.4 1.3 1.1
[110]
SNU475 B4GALNT2
Mean 0.00507
Standard deviation 0.0072
Values 0 0.01
[111]
THLE B4GALNT2
Mean 0.00296
Standard deviation 0.0042
Values 0.0059 0
[112]
liver B4GALNT2
Mean 0
Standard deviation 0
Values 0 0 0 0
[113]
ref_hepatocyte FUT7
Mean 0.0316
Standard deviation 0.045
Values 0 0 0 0.06 0.098
[114]
HepG2 FUT7
Mean 0.744
Standard deviation 0.9
Values 1.4 0.11
[115]
HepG2.C3A FUT7
Mean 0.49
Standard deviation 0.13
Values 0.58 0.4
[116]
HuH.7 FUT7
Mean 0.00214
Standard deviation 0.0037
Values 0 0.0064 0
[117]
SNU475 FUT7
Mean 0.00253
Standard deviation 0.0036
Values 0 0.0051
[118]
THLE FUT7
Mean 0.00562
Standard deviation 0.00042
Values 0.0059 0.0053
[119]
liver FUT7
Mean 0.0961
Standard deviation 0.14
Values 0 0.029 0.051 0.3
[120]
ref_hepatocyte B3GALT2
Mean 0.00862
Standard deviation 0.019
Values 0 0 0 0.043 0
[121]
HepG2 B3GALT2
Mean 0
Standard deviation 0
Values 0 0
[122]
HepG2.C3A B3GALT2
Mean 0.0146
Standard deviation 0.021
Values 0.029 0
[123]
HuH.7 B3GALT2
Mean 0.429
Standard deviation 0.51
Values 0.13 1 0.14
[124]
SNU475 B3GALT2
Mean 8.39
Standard deviation 8.1
Values 14 2.6
[125]
THLE B3GALT2
Mean 0.0316
Standard deviation 0.022
Values 0.047 0.016
[126]
liver B3GALT2
Mean 1.69
Standard deviation 1.1
Values 0.78 3 0.82 2.2
[127]
ref_hepatocyte FUT9
Mean 0.0038
Standard deviation 0.0053
Values 0 0 0.011 0 0.0081
[128]
HepG2 FUT9
Mean 0.0172
Standard deviation 0.024
Values 0 0.034
[129]
HepG2.C3A FUT9
Mean 0.0292
Standard deviation 0.041
Values 0.058 0
[130]
HuH.7 FUT9
Mean 0.0267
Standard deviation 0.034
Values 0.0082 0.0064 0.066
[131]
SNU475 FUT9
Mean 0.0312
Standard deviation 0.0083
Values 0.037 0.025
[132]
THLE FUT9
Mean 0.0319
Standard deviation 0.03
Values 0.053 0.011
[133]
liver FUT9
Mean 0.039
Standard deviation 0.036
Values 0.024 0.014 0.026 0.093
[134]
ref_hepatocyte FUT5
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[135]
HepG2 FUT5
Mean 0.00716
Standard deviation 0.002
Values 0.0057 0.0086
[136]
HepG2.C3A FUT5
Mean 0.0458
Standard deviation 0.004
Values 0.049 0.043
[137]
HuH.7 FUT5
Mean 0.574
Standard deviation 0.47
Values 0.38 1.1 0.23
[138]
SNU475 FUT5
Mean 0.00717
Standard deviation 0.003
Values 0.0093 0.0051
[139]
THLE FUT5
Mean 0
Standard deviation 0
Values 0 0
[140]
liver FUT5
Mean 0.177
Standard deviation 0.042
Values 0.19 0.14 0.23 0.15
[141]
ref_hepatocyte B3GALT1
Mean 0
Standard deviation 0
Values 0 0 0 0 0
[142]
HepG2 B3GALT1
Mean 0.0487
Standard deviation 0.004
Values 0.046 0.051
[143]
HepG2.C3A B3GALT1
Mean 0.00972
Standard deviation 0.014
Values 0.019 0
[144]
HuH.7 B3GALT1
Mean 0.301
Standard deviation 0.18
Values 0.47 0.33 0.1
[145]
SNU475 B3GALT1
Mean 0.0076
Standard deviation 0.011
Values 0 0.015
[146]
THLE B3GALT1
Mean 0.0452
Standard deviation 0.011
Values 0.053 0.037
[147]
liver B3GALT1
Mean 0.0171
Standard deviation 0.021
Values 0 0.043 0.026 0