REACTOME_UBIQUINOL_BIOSYNTHESIS Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 COQ9 Ubiquinone biosynthesis protein COQ9, mitochondrial [1] -0.21[2] -0.60[3] -1.23[4] -0.42[5] -0.34[6] -0.02[7]
2 COQ5 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial [8] -0.44[9] 0.12[10] 0.80[11] 0.21[12] -0.53[13] -0.43[14]
3 COQ3 Ubiquinone biosynthesis O-methyltransferase, mitochondrial [15] -0.95[16] -1.30[17] -0.79[18] -0.49[19] -0.10[20] -1.25[21]
4 COQ6 Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial [22] 0.03[23] 0.59[24] -0.93[25] 0.32[26] 0.30[27] 0.47[28]
5 PDSS2 Decaprenyl-diphosphate synthase subunit 2 [29] 0.63[30] 0.39[31] 0.88[32] -0.30[33] 0.49[34] 1.20[35]
6 COQ2 4-hydroxybenzoate polyprenyltransferase, mitochondrial [36] -0.08[37] -0.52[38] -0.44[39] -0.55[40] 0.70[41] -0.18[42]
7 COQ7 5-demethoxyubiquinone hydroxylase, mitochondrial [43] 1.65[44] 1.36[45] 0.61[46] 0.73[47] 0.73[48] -0.02[49]
8 PDSS1 Decaprenyl-diphosphate synthase subunit 1 [50] 0.75[51] 1.13[52] 1.12[53] 1.52[54] 0.85[55] 0.00[56]
[1]
ref_hepatocyte COQ9
Mean 23.8
Standard deviation 6.2
Values 19 17 24 33 26
[2]
HepG2 COQ9
Mean 28.1
Standard deviation 3.8
Values 25 31
[3]
HepG2.C3A COQ9
Mean 26.6
Standard deviation 4.2
Values 24 30
[4]
HuH.7 COQ9
Mean 11.8
Standard deviation 4.2
Values 11 7.9 16
[5]
SNU475 COQ9
Mean 13.7
Standard deviation 1.5
Values 15 13
[6]
THLE COQ9
Mean 19.9
Standard deviation 1.5
Values 21 19
[7]
liver COQ9
Mean 30.9
Standard deviation 11
Values 33 26 46 19
[8]
ref_hepatocyte COQ5
Mean 16.3
Standard deviation 8
Values 19 10 5.6 22 24
[9]
HepG2 COQ5
Mean 16.3
Standard deviation 0.47
Values 16 17
[10]
HepG2.C3A COQ5
Mean 29.9
Standard deviation 2.6
Values 28 32
[11]
HuH.7 COQ5
Mean 32.8
Standard deviation 3.1
Values 31 31 36
[12]
SNU475 COQ5
Mean 14.4
Standard deviation 2
Values 16 13
[13]
THLE COQ5
Mean 11.9
Standard deviation 0.8
Values 11 12
[14]
liver COQ5
Mean 15.9
Standard deviation 9
Values 23 9.3 25 7
[15]
ref_hepatocyte COQ3
Mean 6.58
Standard deviation 4.2
Values 3.7 12 1.5 6.7 9.1
[16]
HepG2 COQ3
Mean 4.63
Standard deviation 0.3
Values 4.8 4.4
[17]
HepG2.C3A COQ3
Mean 4.52
Standard deviation 2.3
Values 2.9 6.1
[18]
HuH.7 COQ3
Mean 4.42
Standard deviation 2.4
Values 4.9 1.9 6.5
[19]
SNU475 COQ3
Mean 3.6
Standard deviation 0.0035
Values 3.6 3.6
[20]
THLE COQ3
Mean 6.48
Standard deviation 0.91
Values 5.8 7.1
[21]
liver COQ3
Mean 3.64
Standard deviation 2.6
Values 5.4 1.5 6.2 1.4
[22]
ref_hepatocyte COQ6
Mean 5.95
Standard deviation 5.4
Values 2.2 3.1 1.6 14 8.5
[23]
HepG2 COQ6
Mean 8.25
Standard deviation 1.3
Values 7.3 9.2
[24]
HepG2.C3A COQ6
Mean 15.1
Standard deviation 0.61
Values 15 16
[25]
HuH.7 COQ6
Mean 3.63
Standard deviation 0.73
Values 3.6 2.9 4.4
[26]
SNU475 COQ6
Mean 5.7
Standard deviation 0.18
Values 5.8 5.6
[27]
THLE COQ6
Mean 7.71
Standard deviation 0.21
Values 7.6 7.9
[28]
liver COQ6
Mean 10.9
Standard deviation 7
Values 12 7.1 20 4
[29]
ref_hepatocyte PDSS2
Mean 5.1
Standard deviation 2
Values 3.9 4.6 2.7 6.8 7.5
[30]
HepG2 PDSS2
Mean 10.8
Standard deviation 2.8
Values 8.8 13
[31]
HepG2.C3A PDSS2
Mean 11.3
Standard deviation 1.6
Values 10 12
[32]
HuH.7 PDSS2
Mean 10.9
Standard deviation 0.57
Values 11 10 11
[33]
SNU475 PDSS2
Mean 3.17
Standard deviation 0.19
Values 3.3 3
[34]
THLE PDSS2
Mean 7.52
Standard deviation 0.72
Values 7 8
[35]
liver PDSS2
Mean 15.4
Standard deviation 2
Values 16 14 18 13
[36]
ref_hepatocyte COQ2
Mean 5.05
Standard deviation 1.9
Values 6.1 4.7 1.9 6.6 5.9
[37]
HepG2 COQ2
Mean 6.49
Standard deviation 2.5
Values 4.7 8.3
[38]
HepG2.C3A COQ2
Mean 5.97
Standard deviation 2.6
Values 4.2 7.8
[39]
HuH.7 COQ2
Mean 4.32
Standard deviation 1.9
Values 4.4 2.4 6.2
[40]
SNU475 COQ2
Mean 2.65
Standard deviation 0.55
Values 3 2.3
[41]
THLE COQ2
Mean 8.62
Standard deviation 1.3
Values 7.7 9.6
[42]
liver COQ2
Mean 5.88
Standard deviation 3
Values 7.1 4.9 9.2 2.3
[43]
ref_hepatocyte COQ7
Mean 3
Standard deviation 1.6
Values 5.2 3.1 0.67 3 3
[44]
HepG2 COQ7
Mean 12.9
Standard deviation 0.69
Values 12 13
[45]
HepG2.C3A COQ7
Mean 13.1
Standard deviation 2.3
Values 11 15
[46]
HuH.7 COQ7
Mean 5.31
Standard deviation 1.2
Values 5.9 4 6.1
[47]
SNU475 COQ7
Mean 3.81
Standard deviation 0.56
Values 4.2 3.4
[48]
THLE COQ7
Mean 5.23
Standard deviation 2.2
Values 3.7 6.8
[49]
liver COQ7
Mean 3.89
Standard deviation 1.3
Values 4 2.8 5.7 3
[50]
ref_hepatocyte PDSS1
Mean 2.39
Standard deviation 0.94
Values 1.8 3.6 3.2 1.9 1.5
[51]
HepG2 PDSS1
Mean 5.47
Standard deviation 0.88
Values 4.8 6.1
[52]
HepG2.C3A PDSS1
Mean 8.85
Standard deviation 4.4
Values 5.8 12
[53]
HuH.7 PDSS1
Mean 6.03
Standard deviation 3.1
Values 6.3 2.8 8.9
[54]
SNU475 PDSS1
Mean 5.28
Standard deviation 1.6
Values 4.2 6.4
[55]
THLE PDSS1
Mean 4.54
Standard deviation 1.2
Values 3.7 5.4
[56]
liver PDSS1
Mean 3.14
Standard deviation 1
Values 3.6 2.8 4.2 1.9