REACTOME_BIOTIN_TRANSPORT_AND_METABOLISM Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 PCCB Propionyl-CoA carboxylase beta chain, mitochondrial [1] -0.92[2] -1.09[3] -2.56[4] -0.80[5] -0.46[6] -1.71[7]
2 PC Pyruvate carboxylase, mitochondrial [8] -0.87[9] -0.76[10] 0.24[11] -0.44[12] -2.58[13] 0.55[14]
3 MCCC2 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial [15] 0.54[16] 0.39[17] 0.43[18] 0.05[19] 0.49[20] -0.77[21]
4 PCCA Propionyl-CoA carboxylase alpha chain, mitochondrial [22] -1.17[23] -1.17[24] -1.54[25] -2.30[26] -1.90[27] -0.46[28]
5 SLC5A6 Sodium-dependent multivitamin transporter [29] 1.45[30] 1.37[31] 0.00[32] -0.63[33] -0.02[34] 0.49[35]
6 MCCC1 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial [36] -1.19[37] -1.26[38] -0.50[39] -1.28[40] -0.62[41] -1.08[42]
7 BTD Biotinidase [43] -0.94[44] -0.75[45] -1.43[46] -1.19[47] -0.28[48] -0.67[49]
8 PDZD11 PDZ domain-containing protein 11 [50] 0.22[51] -0.04[52] -0.68[53] 1.52[54] 1.73[55] -2.31[56]
9 ACACB Acetyl-CoA carboxylase 2 [57] -0.47[58] 0.40[59] 0.34[60] -0.63[61] -0.02[62] 2.59[63]
10 ACACA Acetyl-CoA carboxylase 1 [64] 2.85[65] 3.09[66] 3.82[67] 3.72[68] 3.23[69] 1.76[70]
11 HLCS Biotin--protein ligase [71] 1.37[72] 1.52[73] 0.76[74] 2.54[75] 2.58[76] 0.83[77]
[1]
ref_hepatocyte PCCB
Mean 41.7
Standard deviation 29
Values 18 27 17 67 79
[2]
HepG2 PCCB
Mean 37
Standard deviation 6.8
Values 32 42
[3]
HepG2.C3A PCCB
Mean 31.3
Standard deviation 3.5
Values 29 34
[4]
HuH.7 PCCB
Mean 12.3
Standard deviation 1.8
Values 13 10 13
[5]
SNU475 PCCB
Mean 20
Standard deviation 5
Values 24 16
[6]
THLE PCCB
Mean 22.8
Standard deviation 3.3
Values 20 25
[7]
liver PCCB
Mean 54.9
Standard deviation 21
Values 55 46 84 34
[8]
ref_hepatocyte PC
Mean 39.5
Standard deviation 46
Values 8 5.6 3.9 87 93
[9]
HepG2 PC
Mean 36.2
Standard deviation 7.4
Values 41 31
[10]
HepG2.C3A PC
Mean 37.2
Standard deviation 8
Values 43 32
[11]
HuH.7 PC
Mean 81.4
Standard deviation 7.4
Values 90 77 77
[12]
SNU475 PC
Mean 24.3
Standard deviation 13
Values 33 15
[13]
THLE PC
Mean 4.93
Standard deviation 0.64
Values 4.5 5.4
[14]
liver PC
Mean 248
Standard deviation 63
Values 1.7e+02 2.7e+02 3.2e+02 2.4e+02
[15]
ref_hepatocyte MCCC2
Mean 24.7
Standard deviation 9.8
Values 22 26 11 27 38
[16]
HepG2 MCCC2
Mean 60.1
Standard deviation 16
Values 49 71
[17]
HepG2.C3A MCCC2
Mean 51.8
Standard deviation 17
Values 40 64
[18]
HuH.7 MCCC2
Mean 58.3
Standard deviation 19
Values 74 37 63
[19]
SNU475 MCCC2
Mean 21.4
Standard deviation 2.4
Values 23 20
[20]
THLE MCCC2
Mean 26.1
Standard deviation 3.3
Values 24 28
[21]
liver MCCC2
Mean 62.1
Standard deviation 26
Values 72 46 94 36
[22]
ref_hepatocyte PCCA
Mean 17.2
Standard deviation 15
Values 9.9 6.1 3.5 37 29
[23]
HepG2 PCCA
Mean 12.9
Standard deviation 1.6
Values 12 14
[24]
HepG2.C3A PCCA
Mean 12.2
Standard deviation 0.74
Values 13 12
[25]
HuH.7 PCCA
Mean 10.3
Standard deviation 0.27
Values 10 11 10
[26]
SNU475 PCCA
Mean 2.91
Standard deviation 0.067
Values 3 2.9
[27]
THLE PCCA
Mean 3.46
Standard deviation 0.45
Values 3.1 3.8
[28]
liver PCCA
Mean 53.8
Standard deviation 7.3
Values 49 58 62 47
[29]
ref_hepatocyte SLC5A6
Mean 14.9
Standard deviation 15
Values 16 4.1 4.7 40 10
[30]
HepG2 SLC5A6
Mean 68.6
Standard deviation 9.5
Values 75 62
[31]
HepG2.C3A SLC5A6
Mean 61.4
Standard deviation 6.8
Values 66 57
[32]
HuH.7 SLC5A6
Mean 26.1
Standard deviation 9.9
Values 34 15 30
[33]
SNU475 SLC5A6
Mean 8.03
Standard deviation 1.1
Values 7.3 8.8
[34]
THLE SLC5A6
Mean 11
Standard deviation 0.48
Values 11 11
[35]
liver SLC5A6
Mean 89.8
Standard deviation 70
Values 48 1e+02 1.8e+02 26
[36]
ref_hepatocyte MCCC1
Mean 13.4
Standard deviation 8.4
Values 5.1 14 4.4 21 22
[37]
HepG2 MCCC1
Mean 9.8
Standard deviation 2
Values 8.4 11
[38]
HepG2.C3A MCCC1
Mean 8.89
Standard deviation 0.017
Values 8.9 8.9
[39]
HuH.7 MCCC1
Mean 16.5
Standard deviation 1.3
Values 16 15 18
[40]
SNU475 MCCC1
Mean 4.59
Standard deviation 1.2
Values 5.4 3.7
[41]
THLE MCCC1
Mean 6.51
Standard deviation 0.64
Values 6.1 7
[42]
liver MCCC1
Mean 27.2
Standard deviation 5.9
Values 27 28 34 20
[43]
ref_hepatocyte BTD
Mean 8.84
Standard deviation 10
Values 2.1 1.8 1.1 15 24
[44]
HepG2 BTD
Mean 7.7
Standard deviation 0.5
Values 7.4 8.1
[45]
HepG2.C3A BTD
Mean 8.4
Standard deviation 0.021
Values 8.4 8.4
[46]
HuH.7 BTD
Mean 5.74
Standard deviation 0.4
Values 5.5 6.2 5.5
[47]
SNU475 BTD
Mean 3.22
Standard deviation 0.56
Values 3.6 2.8
[48]
THLE BTD
Mean 5.46
Standard deviation 0.75
Values 4.9 6
[49]
liver BTD
Mean 23.9
Standard deviation 2
Values 23 24 26 21
[50]
ref_hepatocyte PDZD11
Mean 7.69
Standard deviation 3.4
Values 3 8.2 5.6 11 11
[51]
HepG2 PDZD11
Mean 15
Standard deviation 2.5
Values 13 17
[52]
HepG2.C3A PDZD11
Mean 12
Standard deviation 3.4
Values 9.5 14
[53]
HuH.7 PDZD11
Mean 8.35
Standard deviation 1.3
Values 8.5 7 9.6
[54]
SNU475 PDZD11
Mean 18.3
Standard deviation 4.5
Values 21 15
[55]
THLE PDZD11
Mean 19.1
Standard deviation 2.2
Values 18 21
[56]
liver PDZD11
Mean 6.65
Standard deviation 5.4
Values 11 2.4 11 1.6
[57]
ref_hepatocyte ACACB
Mean 5.46
Standard deviation 5.5
Values 1.7 1.8 1.1 9.6 13
[58]
HepG2 ACACB
Mean 6.6
Standard deviation 0.54
Values 6.2 7
[59]
HepG2.C3A ACACB
Mean 11.5
Standard deviation 0.088
Values 11 12
[60]
HuH.7 ACACB
Mean 12.1
Standard deviation 1.9
Values 13 13 9.8
[61]
SNU475 ACACB
Mean 2.94
Standard deviation 0.034
Values 3 2.9
[62]
THLE ACACB
Mean 4.04
Standard deviation 0.24
Values 4.2 3.9
[63]
liver ACACB
Mean 141
Standard deviation 89
Values 90 1.6e+02 59 2.6e+02
[64]
ref_hepatocyte ACACA
Mean 3.02
Standard deviation 0.95
Values 4.3 3.2 1.7 3.2 2.7
[65]
HepG2 ACACA
Mean 36.5
Standard deviation 4.8
Values 33 40
[66]
HepG2.C3A ACACA
Mean 41.2
Standard deviation 13
Values 50 32
[67]
HuH.7 ACACA
Mean 74.7
Standard deviation 16
Values 89 78 57
[68]
SNU475 ACACA
Mean 33.2
Standard deviation 14
Values 43 23
[69]
THLE ACACA
Mean 21.2
Standard deviation 5
Values 18 25
[70]
liver ACACA
Mean 44
Standard deviation 21
Values 21 70 35 50
[71]
ref_hepatocyte HLCS
Mean 2.02
Standard deviation 0.54
Values 1.6 1.6 1.9 2 2.9
[72]
HepG2 HLCS
Mean 8.73
Standard deviation 0.85
Values 8.1 9.3
[73]
HepG2.C3A HLCS
Mean 9.23
Standard deviation 0.52
Values 8.9 9.6
[74]
HuH.7 HLCS
Mean 5.98
Standard deviation 0.68
Values 6.7 5.8 5.4
[75]
SNU475 HLCS
Mean 9.79
Standard deviation 2.9
Values 12 7.7
[76]
THLE HLCS
Mean 9.03
Standard deviation 1.3
Values 8.1 9.9
[77]
liver HLCS
Mean 15.4
Standard deviation 3.7
Values 12 20 16 14