REACTOME_TRISTETRAPROLIN_TTP_ZFP36_BINDS_AND_DESTABILIZES_MRNA Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 YWHAB 14-3-3 protein beta/alpha [1] 0.92[2] 0.46[3] -0.13[4] 0.68[5] 0.38[6] -0.14[7]
2 ZFP36 mRNA decay activator protein ZFP36 [8] -2.54[9] -2.27[10] -3.27[11] -2.64[12] -2.99[13] -0.37[14]
3 EXOSC4 Exosome complex component RRP41 [15] -1.63[16] -1.44[17] -1.95[18] -2.46[19] -2.87[20] -1.71[21]
4 EXOSC7 Exosome complex component RRP42 [22] -1.47[23] -1.66[24] -0.96[25] -3.33[26] -2.11[27] -1.89[28]
5 EXOSC3 Exosome complex component RRP40 [29] -1.22[30] -1.50[31] -0.65[32] -2.55[33] -1.62[34] -1.86[35]
6 MAPKAPK2 MAP kinase-activated protein kinase 2 [36] 0.35[37] -0.79[38] -0.25[39] 0.78[40] 0.25[41] -0.98[42]
7 EXOSC9 Exosome complex component RRP45 [43] -1.45[44] -1.18[45] -1.58[46] -2.06[47] -0.11[48] -2.18[49]
8 EXOSC5 Exosome complex component RRP46 [50] -1.05[51] -1.20[52] 0.00[53] -2.53[54] -1.83[55] -1.11[56]
9 TNPO1 Transportin-1 [57] 1.62[58] 2.09[59] 2.10[60] 2.87[61] 2.55[62] 2.03[63]
10 EXOSC2 Exosome complex component RRP4 [64] 0.11[65] -0.23[66] 0.22[67] -0.95[68] 0.26[69] -0.74[70]
11 EXOSC1 Exosome complex component CSL4 [71] -0.20[72] 0.30[73] 0.73[74] -1.52[75] -0.34[76] -1.00[77]
12 EXOSC6 Exosome complex component MTR3 [78] -0.33[79] -0.48[80] -1.58[81] -1.67[82] -0.82[83] -0.68[84]
13 EXOSC8 Exosome complex component RRP43 [85] 0.04[86] 0.69[87] 1.01[88] -1.35[89] -0.04[90] -0.71[91]
14 DIS3 Exosome complex exonuclease RRP44 [92] 0.79[93] 1.64[94] 2.44[95] 1.18[96] 1.49[97] 1.91[98]
15 DCP1A mRNA-decapping enzyme 1A [99] 1.71[100] 1.91[101] 1.47[102] 0.77[103] 1.91[104] 2.71[105]
16 DCP2 m7GpppN-mRNA hydrolase [106] 1.68[107] 3.22[108] 2.51[109] 1.82[110] 1.97[111] 3.16[112]
17 XRN1 5'-3' exoribonuclease 1 [113] 0.73[114] 2.07[115] 2.59[116] 2.33[117] 2.46[118] 4.45[119]
[1]
ref_hepatocyte YWHAB
Mean 42.6
Standard deviation 20
Values 74 47 41 28 22
[2]
HepG2 YWHAB
Mean 193
Standard deviation 37
Values 1.7e+02 2.2e+02
[3]
HepG2.C3A YWHAB
Mean 141
Standard deviation 27
Values 1.2e+02 1.6e+02
[4]
HuH.7 YWHAB
Mean 82.2
Standard deviation 26
Values 98 52 97
[5]
SNU475 YWHAB
Mean 193
Standard deviation 7
Values 2e+02 1.9e+02
[6]
THLE YWHAB
Mean 146
Standard deviation 23
Values 1.3e+02 1.6e+02
[7]
liver YWHAB
Mean 56.6
Standard deviation 26
Values 78 39 80 30
[8]
ref_hepatocyte ZFP36
Mean 24.3
Standard deviation 25
Values 3.5 7.8 24 66 20
[9]
HepG2 ZFP36
Mean 9.99
Standard deviation 4.3
Values 13 7
[10]
HepG2.C3A ZFP36
Mean 12.1
Standard deviation 6.6
Values 17 7.5
[11]
HuH.7 ZFP36
Mean 5.32
Standard deviation 1.4
Values 4.1 6.8 5
[12]
SNU475 ZFP36
Mean 11
Standard deviation 5.1
Values 15 7.4
[13]
THLE ZFP36
Mean 8.03
Standard deviation 1.3
Values 9 7.1
[14]
liver ZFP36
Mean 27.6
Standard deviation 31
Values 65 2.2 40 3.2
[15]
ref_hepatocyte EXOSC4
Mean 20
Standard deviation 9.6
Values 7.2 18 34 23 18
[16]
HepG2 EXOSC4
Mean 15.4
Standard deviation 1
Values 16 15
[17]
HepG2.C3A EXOSC4
Mean 17.7
Standard deviation 0.81
Values 18 17
[18]
HuH.7 EXOSC4
Mean 10.9
Standard deviation 5
Values 12 5.5 15
[19]
SNU475 EXOSC4
Mean 10.2
Standard deviation 1.9
Values 8.9 12
[20]
THLE EXOSC4
Mean 7.19
Standard deviation 1.1
Values 6.4 8
[21]
liver EXOSC4
Mean 8.91
Standard deviation 7.7
Values 18 2.2 13 2.8
[22]
ref_hepatocyte EXOSC7
Mean 19.5
Standard deviation 5.3
Values 20 25 24 15 13
[23]
HepG2 EXOSC7
Mean 16.8
Standard deviation 1.4
Values 18 16
[24]
HepG2.C3A EXOSC7
Mean 14.8
Standard deviation 0.76
Values 15 14
[25]
HuH.7 EXOSC7
Mean 21.1
Standard deviation 7.8
Values 22 13 28
[26]
SNU475 EXOSC7
Mean 5.45
Standard deviation 0.71
Values 6 4.9
[27]
THLE EXOSC7
Mean 11.8
Standard deviation 0.76
Values 11 12
[28]
liver EXOSC7
Mean 7.69
Standard deviation 4.4
Values 12 4.5 11 3.4
[29]
ref_hepatocyte EXOSC3
Mean 15.3
Standard deviation 11
Values 24 29 9.4 7.1 6.5
[30]
HepG2 EXOSC3
Mean 15.6
Standard deviation 2
Values 14 17
[31]
HepG2.C3A EXOSC3
Mean 13
Standard deviation 5
Values 9.5 17
[32]
HuH.7 EXOSC3
Mean 20.5
Standard deviation 9.1
Values 23 10 28
[33]
SNU475 EXOSC3
Mean 7.33
Standard deviation 0.48
Values 7 7.7
[34]
THLE EXOSC3
Mean 13
Standard deviation 1.4
Values 12 14
[35]
liver EXOSC3
Mean 6.17
Standard deviation 1.8
Values 7.1 4.7 8.3 4.6
[36]
ref_hepatocyte MAPKAPK2
Mean 13.1
Standard deviation 7.6
Values 5.2 10 24 17 8.7
[37]
HepG2 MAPKAPK2
Mean 39.7
Standard deviation 1.4
Values 41 39
[38]
HepG2.C3A MAPKAPK2
Mean 18.1
Standard deviation 4.5
Values 21 15
[39]
HuH.7 MAPKAPK2
Mean 23.2
Standard deviation 2.9
Values 25 20 25
[40]
SNU475 MAPKAPK2
Mean 63.2
Standard deviation 4
Values 66 60
[41]
THLE MAPKAPK2
Mean 40.9
Standard deviation 0.33
Values 41 41
[42]
liver MAPKAPK2
Mean 9.67
Standard deviation 2.5
Values 10 11 6 11
[43]
ref_hepatocyte EXOSC9
Mean 11.8
Standard deviation 9.9
Values 17 27 6.1 4.9 4
[44]
HepG2 EXOSC9
Mean 10.3
Standard deviation 2.7
Values 8.4 12
[45]
HepG2.C3A EXOSC9
Mean 12.5
Standard deviation 4.3
Values 9.4 16
[46]
HuH.7 EXOSC9
Mean 8.29
Standard deviation 1.6
Values 8.5 6.6 9.8
[47]
SNU475 EXOSC9
Mean 7.97
Standard deviation 2
Values 6.6 9.4
[48]
THLE EXOSC9
Mean 28.7
Standard deviation 1
Values 29 28
[49]
liver EXOSC9
Mean 3.81
Standard deviation 1.1
Values 5.2 3.3 4.1 2.7
[50]
ref_hepatocyte EXOSC5
Mean 10.7
Standard deviation 6.4
Values 3.4 5.9 17 18 9.8
[51]
HepG2 EXOSC5
Mean 12.3
Standard deviation 4.6
Values 16 9.1
[52]
HepG2.C3A EXOSC5
Mean 11.2
Standard deviation 0.51
Values 11 12
[53]
HuH.7 EXOSC5
Mean 22.5
Standard deviation 11
Values 26 9.8 31
[54]
SNU475 EXOSC5
Mean 5.21
Standard deviation 1.6
Values 4 6.4
[55]
THLE EXOSC5
Mean 7.89
Standard deviation 0.98
Values 7.2 8.6
[56]
liver EXOSC5
Mean 7.26
Standard deviation 6.1
Values 13 2.2 12 1.8
[57]
ref_hepatocyte TNPO1
Mean 8.11
Standard deviation 5.2
Values 9.1 16 8.7 3 3.9
[58]
HepG2 TNPO1
Mean 59.4
Standard deviation 26
Values 41 77
[59]
HepG2.C3A TNPO1
Mean 83.3
Standard deviation 21
Values 68 98
[60]
HuH.7 TNPO1
Mean 73.4
Standard deviation 13
Values 83 78 59
[61]
SNU475 TNPO1
Mean 167
Standard deviation 10
Values 1.6e+02 1.7e+02
[62]
THLE TNPO1
Mean 125
Standard deviation 5.8
Values 1.3e+02 1.2e+02
[63]
liver TNPO1
Mean 48.3
Standard deviation 35
Values 21 88 17 67
[64]
ref_hepatocyte EXOSC2
Mean 7.07
Standard deviation 2.8
Values 6.3 12 7.1 6.6 3.7
[65]
HepG2 EXOSC2
Mean 18.3
Standard deviation 0.66
Values 18 19
[66]
HepG2.C3A EXOSC2
Mean 14.5
Standard deviation 5.8
Values 10 19
[67]
HuH.7 EXOSC2
Mean 17.3
Standard deviation 8.4
Values 20 7.8 24
[68]
SNU475 EXOSC2
Mean 10.3
Standard deviation 1.6
Values 9.2 11
[69]
THLE EXOSC2
Mean 22.3
Standard deviation 6.3
Values 18 27
[70]
liver EXOSC2
Mean 6.22
Standard deviation 0.73
Values 5.8 6.9 6.7 5.4
[71]
ref_hepatocyte EXOSC1
Mean 6.86
Standard deviation 3.7
Values 3.9 5 4 12 9
[72]
HepG2 EXOSC1
Mean 14.2
Standard deviation 0.4
Values 15 14
[73]
HepG2.C3A EXOSC1
Mean 20.3
Standard deviation 1.4
Values 19 21
[74]
HuH.7 EXOSC1
Mean 24
Standard deviation 5.1
Values 23 19 29
[75]
SNU475 EXOSC1
Mean 6.72
Standard deviation 0.24
Values 6.9 6.5
[76]
THLE EXOSC1
Mean 14.3
Standard deviation 0.39
Values 15 14
[77]
liver EXOSC1
Mean 5.02
Standard deviation 3.7
Values 8.6 2 7.9 1.6
[78]
ref_hepatocyte EXOSC6
Mean 6.69
Standard deviation 5
Values 15 5.3 4 3.2 5.5
[79]
HepG2 EXOSC6
Mean 12.7
Standard deviation 0.74
Values 13 12
[80]
HepG2.C3A EXOSC6
Mean 11.5
Standard deviation 1.3
Values 11 12
[81]
HuH.7 EXOSC6
Mean 4.71
Standard deviation 1.3
Values 4.4 3.6 6.2
[82]
SNU475 EXOSC6
Mean 5.93
Standard deviation 0.11
Values 5.9 6
[83]
THLE EXOSC6
Mean 9.98
Standard deviation 1.4
Values 9 11
[84]
liver EXOSC6
Mean 6.12
Standard deviation 2.8
Values 3.1 7.5 4.5 9.4
[85]
ref_hepatocyte EXOSC8
Mean 5.67
Standard deviation 0.99
Values 4.8 5.8 4.7 7.1 5.9
[86]
HepG2 EXOSC8
Mean 13.9
Standard deviation 2.4
Values 12 16
[87]
HepG2.C3A EXOSC8
Mean 21.9
Standard deviation 7.8
Values 16 27
[88]
HuH.7 EXOSC8
Mean 24
Standard deviation 11
Values 24 13 35
[89]
SNU475 EXOSC8
Mean 6.25
Standard deviation 0.33
Values 6 6.5
[90]
THLE EXOSC8
Mean 14.5
Standard deviation 0.013
Values 15 15
[91]
liver EXOSC8
Mean 5.08
Standard deviation 4
Values 8.7 1.9 8.3 1.4
[92]
ref_hepatocyte DIS3
Mean 3.36
Standard deviation 0.85
Values 3.9 3.2 4.6 2.8 2.4
[93]
HepG2 DIS3
Mean 13.9
Standard deviation 5.1
Values 10 17
[94]
HepG2.C3A DIS3
Mean 25.1
Standard deviation 4.1
Values 22 28
[95]
HuH.7 DIS3
Mean 38.4
Standard deviation 2.7
Values 42 37 36
[96]
SNU475 DIS3
Mean 21.4
Standard deviation 0.63
Values 21 22
[97]
THLE DIS3
Mean 24.8
Standard deviation 1.5
Values 26 24
[98]
liver DIS3
Mean 18.5
Standard deviation 4.7
Values 16 25 15 19
[99]
ref_hepatocyte DCP1A
Mean 1.83
Standard deviation 1.1
Values 3.5 1.5 2.5 0.84 0.81
[100]
HepG2 DCP1A
Mean 14.3
Standard deviation 0.89
Values 15 14
[101]
HepG2.C3A DCP1A
Mean 16.6
Standard deviation 4.4
Values 20 13
[102]
HuH.7 DCP1A
Mean 10.7
Standard deviation 2.4
Values 11 13 8.3
[103]
SNU475 DCP1A
Mean 8.77
Standard deviation 0.21
Values 8.9 8.6
[104]
THLE DCP1A
Mean 18.1
Standard deviation 0.25
Values 18 18
[105]
liver DCP1A
Mean 17.6
Standard deviation 11
Values 27 8.2 27 8.4
[106]
ref_hepatocyte DCP2
Mean 1.54
Standard deviation 1.2
Values 3.4 2.2 0.65 0.48 1
[107]
HepG2 DCP2
Mean 11.8
Standard deviation 4.5
Values 8.6 15
[108]
HepG2.C3A DCP2
Mean 34.5
Standard deviation 0.73
Values 34 35
[109]
HuH.7 DCP2
Mean 18.4
Standard deviation 1.8
Values 21 17 18
[110]
SNU475 DCP2
Mean 15.3
Standard deviation 1.8
Values 17 14
[111]
THLE DCP2
Mean 15.9
Standard deviation 2.3
Values 17 14
[112]
liver DCP2
Mean 20.1
Standard deviation 9
Values 10 31 15 24
[113]
ref_hepatocyte XRN1
Mean 1.16
Standard deviation 0.38
Values 1.2 0.93 0.77 1.1 1.8
[114]
HepG2 XRN1
Mean 4.6
Standard deviation 2.1
Values 3.1 6.1
[115]
HepG2.C3A XRN1
Mean 11.7
Standard deviation 1.4
Values 13 11
[116]
HuH.7 XRN1
Mean 14.7
Standard deviation 7.6
Values 13 23 7.7
[117]
SNU475 XRN1
Mean 16.4
Standard deviation 4
Values 19 14
[118]
THLE XRN1
Mean 16.8
Standard deviation 3.5
Values 19 14
[119]
liver XRN1
Mean 37.2
Standard deviation 15
Values 32 51 19 47