REACTOME_TRIGLYCERIDE_METABOLISM | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | FABP1 | Fatty acid-binding protein, liver | [1] | -6.57[2] | -1.48[3] | -1.44[4] | -10.65[5] | -10.01[6] | -0.87[7] |
2 | PPP1CA | Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | [8] | 3.05[9] | 1.71[10] | 2.77[11] | 4.28[12] | 2.46[13] | 0.42[14] |
3 | DGAT2 | Diacylglycerol O-acyltransferase 2 | [15] | 2.40[16] | 0.47[17] | -0.58[18] | -1.77[19] | 0.15[20] | 1.85[21] |
4 | PPP1CB | Serine/threonine-protein phosphatase PP1-beta catalytic subunit | [22] | 2.83[23] | 2.33[24] | 2.27[25] | 3.51[26] | 3.91[27] | 1.86[28] |
5 | PPP1CC | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit | 3.75[29] | 3.47[30] | 3.54[31] | 2.99[32] | 3.67[33] | 0.29[34] | |
6 | MGLL | Monoglyceride lipase | [35] | -6.51[36] | -6.14[37] | 1.78[38] | -0.51[39] | 0.18[40] | 2.60[41] |
7 | CAV1 | Caveolin-1 | [42] | -3.76[43] | -7.66[44] | -1.53[45] | 4.13[46] | 3.35[47] | -0.63[48] |
8 | PLIN3 | Perilipin-3 | [49] | 4.05[50] | 2.84[51] | 1.95[52] | 2.93[53] | 2.90[54] | 0.18[55] |
9 | PRKACA | cAMP-dependent protein kinase catalytic subunit alpha | [56] | 2.91[57] | 1.67[58] | 1.52[59] | 2.28[60] | 3.45[61] | 0.59[62] |
10 | GPAM | Glycerol-3-phosphate acyltransferase 1, mitochondrial | [63] | 3.99[64] | 4.39[65] | 2.99[66] | -0.56[67] | 4.16[68] | 4.04[69] |
11 | FABP5 | Fatty acid-binding protein, epidermal | [70] | 3.31[71] | 1.67[72] | 2.31[73] | 0.58[74] | 1.62[75] | -3.05[76] |
12 | AGMO | Alkylglycerol monooxygenase | [77] | -2.59[78] | -5.74[79] | 0.06[80] | -5.53[81] | -6.97[82] | 2.21[83] |
13 | GK | Glycerol kinase | [84] | 3.50[85] | 4.56[86] | 3.25[87] | -0.75[88] | 1.99[89] | 3.37[90] |
14 | LPIN2 | Phosphatidate phosphatase LPIN2 | [91] | 4.19[92] | 3.76[93] | 4.26[94] | 3.52[95] | 3.61[96] | 4.00[97] |
15 | LPIN1 | Phosphatidate phosphatase LPIN1 | [98] | 1.49[99] | 2.24[100] | 1.03[101] | 3.27[102] | 2.91[103] | 2.81[104] |
16 | DGAT1 | Diacylglycerol O-acyltransferase 1 | [105] | 4.38[106] | 3.14[107] | 3.49[108] | 2.42[109] | 2.85[110] | 1.57[111] |
17 | PNPLA4 | Patatin-like phospholipase domain-containing protein 4 | [112] | 2.92[113] | 1.85[114] | 1.83[115] | 1.66[116] | 3.57[117] | 1.78[118] |
18 | MOGAT2 | 2-acylglycerol O-acyltransferase 2 | [119] | 1.39[120] | 1.14[121] | -8.53[122] | -7.83[123] | -6.64[124] | 1.76[125] |
19 | ABHD5 | 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 | [126] | 1.79[127] | 1.14[128] | 2.10[129] | 2.19[130] | 4.30[131] | 2.29[132] |
20 | PRKACB | cAMP-dependent protein kinase catalytic subunit beta | [133] | 2.24[134] | 1.95[135] | 3.08[136] | 4.98[137] | 4.42[138] | 3.08[139] |
21 | MOGAT3 | 2-acylglycerol O-acyltransferase 3 | [140] | 3.88[141] | 3.32[142] | 1.61[143] | -5.42[144] | -5.18[145] | 0.51[146] |
22 | PLIN1 | Perilipin-1 | [147] | -0.79[148] | -1.47[149] | -2.55[150] | -1.49[151] | -1.60[152] | 3.38[153] |
23 | LPIN3 | Phosphatidate phosphatase LPIN3 | [154] | 4.65[155] | 4.60[156] | 2.56[157] | 4.16[158] | 4.33[159] | 5.03[160] |
24 | FABP3 | Fatty acid-binding protein, heart | [161] | 0.69[162] | 0.47[163] | -0.64[164] | 1.06[165] | 1.41[166] | 1.10[167] |
25 | GPD2 | Glycerol-3-phosphate dehydrogenase, mitochondrial | [168] | -0.77[169] | -1.35[170] | 6.98[171] | 6.90[172] | 6.96[173] | 3.36[174] |
26 | MOGAT1 | 2-acylglycerol O-acyltransferase 1 | [175] | 1.54[176] | 0.25[177] | 0.43[178] | -2.51[179] | -4.25[180] | 4.12[181] |
27 | GPAT2 | Glycerol-3-phosphate acyltransferase 2, mitochondrial | [182] | 0.50[183] | 0.76[184] | 3.43[185] | 7.90[186] | 2.13[187] | 3.33[188] |
28 | FABP2 | Fatty acid-binding protein, intestinal | [189] | 1.64[190] | 4.30[191] | -1.30[192] | [193] | -1.61[194] | -0.17[195] |
29 | LIPE | Hormone-sensitive lipase | [196] | -1.77[197] | [198] | 1.55[199] | 4.80[200] | 5.37[201] | 3.50[202] |
30 | FABP4 | Fatty acid-binding protein, adipocyte | [203] | [204] | [205] | [206] | [207] | -1.70[208] | 4.53[209] |
31 | PNPLA5 | Patatin-like phospholipase domain-containing protein 5 | [210] | [211] | -1.82[212] | [213] | [214] | -0.58[215] | -1.69[216] |
32 | FABP9 | Fatty acid-binding protein 9 | [217] | [218] | [219] | [220] | [221] | [222] | [223] |
33 | GK2 | Glycerol kinase 2 | [224] | [225] | [226] | [227] | [228] | [229] | [230] |
34 | FABP12 | Fatty acid-binding protein 12 | [231] | [232] | [233] | [234] | [235] | [236] | [237] |
35 | PRKACG | cAMP-dependent protein kinase catalytic subunit gamma | [238] | [239] | [240] | [241] | [242] | [243] | [244] |
36 | FABP6 | Gastrotropin | [245] | [246] | [247] | [248] | [249] | [250] | [251] |
37 | FABP7 | Fatty acid-binding protein, brain | [252] | [253] | [254] | [255] | [256] | [257] | [258] |
38 | GK3P | Glycerol kinase 3 | [259] | [260] | [261] | [262] | [263] | [264] | [265] |