REACTOME_TRIF_MEDIATED_PROGRAMMED_CELL_DEATH Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 CD14 Monocyte differentiation antigen CD14 [1] -5.67[2] -5.69[3] -2.89[4] -3.26[5] -4.09[6] -0.14[7]
2 FADD FAS-associated death domain protein [8] 2.71[9] 2.05[10] 2.76[11] 3.48[12] 1.65[13] -1.40[14]
3 CASP8 Caspase-8 [15] 2.69[16] 3.31[17] 2.47[18] 1.46[19] 1.08[20] -1.05[21]
4 TICAM1 TIR domain-containing adapter molecule 1 [22] 1.96[23] 0.91[24] 1.82[25] 0.32[26] 1.73[27] -0.13[28]
5 RIPK1 Receptor-interacting serine/threonine-protein kinase 1 [29] 2.96[30] 3.17[31] 2.84[32] 2.62[33] 2.50[34] 1.85[35]
6 LY96 Lymphocyte antigen 96 [36] 0.02[37] -0.32[38] -6.75[39] 0.18[40] -3.08[41] -1.00[42]
7 TLR4 Toll-like receptor 4 [43] 2.94[44] -2.16[45] -3.07[46] -3.55[47] 7.22[48] 4.83[49]
8 TICAM2 TIR domain-containing adapter molecule 2 [50] -5.21[51] [52] -4.59[53] 0.05[54] 0.75[55] -1.61[56]
9 RIPK3 Receptor-interacting serine/threonine-protein kinase 3 [57] -3.98[58] [59] -2.62[60] [61] -3.48[62] 0.92[63]
[1]
ref_hepatocyte CD14
Mean 148
Standard deviation 1.9e+02
Values 0.7 1.6 16 3.4e+02 3.8e+02
[2]
HepG2 CD14
Mean 1.01
Standard deviation 0.084
Values 1.1 0.95
[3]
HepG2.C3A CD14
Mean 0.856
Standard deviation 0.32
Values 1.1 0.63
[4]
HuH.7 CD14
Mean 5.78
Standard deviation 1.1
Values 5.8 4.7 6.9
[5]
SNU475 CD14
Mean 9.74
Standard deviation 1.9
Values 8.4 11
[6]
THLE CD14
Mean 4.8
Standard deviation 0.97
Values 5.5 4.1
[7]
liver CD14
Mean 148
Standard deviation 88
Values 2.1e+02 68 2.4e+02 77
[8]
ref_hepatocyte FADD
Mean 9.28
Standard deviation 6.6
Values 3.8 12 20 6.3 5.1
[9]
HepG2 FADD
Mean 21.1
Standard deviation 4.6
Values 24 18
[10]
HepG2.C3A FADD
Mean 11.5
Standard deviation 1.6
Values 10 13
[11]
HuH.7 FADD
Mean 18.2
Standard deviation 3.2
Values 16 16 22
[12]
SNU475 FADD
Mean 65.1
Standard deviation 11
Values 73 58
[13]
THLE FADD
Mean 16
Standard deviation 3.5
Values 14 19
[14]
liver FADD
Mean 3.86
Standard deviation 1.3
Values 2.5 4.9 3 5.1
[15]
ref_hepatocyte CASP8
Mean 8.88
Standard deviation 6.8
Values 18 13 8.9 1.9 2.8
[16]
HepG2 CASP8
Mean 19.9
Standard deviation 3.1
Values 22 18
[17]
HepG2.C3A CASP8
Mean 26.3
Standard deviation 13
Values 17 35
[18]
HuH.7 CASP8
Mean 14.2
Standard deviation 3.6
Values 14 11 18
[19]
SNU475 CASP8
Mean 15.4
Standard deviation 0.7
Values 16 15
[20]
THLE CASP8
Mean 10.3
Standard deviation 0.97
Values 9.6 11
[21]
liver CASP8
Mean 4.72
Standard deviation 0.87
Values 3.4 5.2 5.3 5
[22]
ref_hepatocyte TICAM1
Mean 4.75
Standard deviation 6.4
Values 0 1.4 16 3.4 3
[23]
HepG2 TICAM1
Mean 6.41
Standard deviation 2.9
Values 8.5 4.3
[24]
HepG2.C3A TICAM1
Mean 2.66
Standard deviation 0.59
Values 3.1 2.2
[25]
HuH.7 TICAM1
Mean 4.87
Standard deviation 0.33
Values 5.2 4.5 4.9
[26]
SNU475 TICAM1
Mean 3.73
Standard deviation 0.28
Values 3.5 3.9
[27]
THLE TICAM1
Mean 8.64
Standard deviation 1.3
Values 7.7 9.5
[28]
liver TICAM1
Mean 4.77
Standard deviation 3.4
Values 7.9 1.4 7.4 2.3
[29]
ref_hepatocyte RIPK1
Mean 4.28
Standard deviation 0.89
Values 3.7 4.4 3.1 5.4 4.8
[30]
HepG2 RIPK1
Mean 11.5
Standard deviation 4
Values 8.7 14
[31]
HepG2.C3A RIPK1
Mean 11.5
Standard deviation 0.53
Values 11 12
[32]
HuH.7 RIPK1
Mean 8.85
Standard deviation 0.42
Values 8.4 9.3 8.8
[33]
SNU475 RIPK1
Mean 16.6
Standard deviation 2.9
Values 19 15
[34]
THLE RIPK1
Mean 13.4
Standard deviation 1
Values 13 14
[35]
liver RIPK1
Mean 17
Standard deviation 5.1
Values 12 21 13 22
[36]
ref_hepatocyte LY96
Mean 2.98
Standard deviation 1.7
Values 3 4.2 0 4 3.7
[37]
HepG2 LY96
Mean 1.05
Standard deviation 0.03
Values 1 1.1
[38]
HepG2.C3A LY96
Mean 0.711
Standard deviation 0.08
Values 0.77 0.65
[39]
HuH.7 LY96
Mean 0.008
Standard deviation 0.0015
Values 0.0082 0.0064 0.0094
[40]
SNU475 LY96
Mean 2.13
Standard deviation 0.56
Values 2.5 1.7
[41]
THLE LY96
Mean 0.194
Standard deviation 0.13
Values 0.1 0.29
[42]
liver LY96
Mean 1.65
Standard deviation 1.4
Values 2.6 0.6 3 0.34
[43]
ref_hepatocyte TLR4
Mean 0.547
Standard deviation 0.41
Values 0 1.1 0.33 0.64 0.66
[44]
HepG2 TLR4
Mean 1.46
Standard deviation 0.9
Values 0.82 2.1
[45]
HepG2.C3A TLR4
Mean 0.0365
Standard deviation 0.024
Values 0.019 0.054
[46]
HuH.7 TLR4
Mean 0.0189
Standard deviation 0.019
Values 0 0.019 0.037
[47]
SNU475 TLR4
Mean 0.0293
Standard deviation 0.0087
Values 0.023 0.035
[48]
THLE TLR4
Mean 45
Standard deviation 10
Values 52 38
[49]
liver TLR4
Mean 17.2
Standard deviation 6.3
Values 13 19 11 25
[50]
ref_hepatocyte TICAM2
Mean 0.456
Standard deviation 0.51
Values 0 0.53 0 0.51 1.2
[51]
HepG2 TICAM2
Mean 0.00429
Standard deviation 0.0061
Values 0 0.0086
[52]
HepG2.C3A TICAM2
Mean 0
Standard deviation 0
Values 0 0
[53]
HuH.7 TICAM2
Mean 0.00547
Standard deviation 0.0095
Values 0.016 0 0
[54]
SNU475 TICAM2
Mean 0.297
Standard deviation 0.053
Values 0.26 0.33
[55]
THLE TICAM2
Mean 0.422
Standard deviation 0.036
Values 0.4 0.45
[56]
liver TICAM2
Mean 0.164
Standard deviation 0.11
Values 0.21 0.14 0.026 0.28
[57]
ref_hepatocyte RIPK3
Mean 0.227
Standard deviation 0.15
Values 0 0.37 0.33 0.15 0.29
[58]
HepG2 RIPK3
Mean 0.00501
Standard deviation 0.001
Values 0.0057 0.0043
[59]
HepG2.C3A RIPK3
Mean 0
Standard deviation 0
Values 0 0
[60]
HuH.7 RIPK3
Mean 0.0107
Standard deviation 0.019
Values 0 0.032 0
[61]
SNU475 RIPK3
Mean 0
Standard deviation 0
Values 0 0
[62]
THLE RIPK3
Mean 0.0112
Standard deviation 0.00084
Values 0.012 0.011
[63]
liver RIPK3
Mean 0.474
Standard deviation 0.21
Values 0.78 0.43 0.36 0.33