REACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGO | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | SLC3A2 | 4F2 cell-surface antigen heavy chain | [1] | -0.72[2] | -2.05[3] | -1.71[4] | -1.12[5] | -0.51[6] | -3.11[7] |
2 | SLC38A3 | Sodium-coupled neutral amino acid transporter 3 | [8] | -3.84[9] | -1.94[10] | -1.86[11] | -6.93[12] | -7.12[13] | -0.73[14] |
3 | SLC38A2 | Sodium-coupled neutral amino acid transporter 2 | [15] | 0.26[16] | 1.66[17] | -0.67[18] | -0.16[19] | 0.45[20] | 0.40[21] |
4 | SLC38A4 | Sodium-coupled neutral amino acid transporter 4 | [22] | -7.21[23] | -7.08[24] | -3.59[25] | -3.14[26] | -11.84[27] | 0.54[28] |
5 | CALM1 | Calmodulin-1 | [29] | -0.59[30] | -0.80[31] | -0.13[32] | 1.31[33] | 0.63[34] | 0.56[35] |
6 | SLC43A1 | Large neutral amino acids transporter small subunit 3 | [36] | -0.73[37] | -0.47[38] | 0.96[39] | -5.20[40] | -3.51[41] | 0.27[42] |
7 | SLC7A5 | Large neutral amino acids transporter small subunit 1 | [43] | 2.21[44] | 0.74[45] | -0.15[46] | -0.39[47] | 0.42[48] | -2.82[49] |
8 | SLC25A10 | Mitochondrial dicarboxylate carrier | [50] | -0.06[51] | -0.50[52] | -1.99[53] | -2.24[54] | -1.78[55] | -1.56[56] |
9 | SLC7A2 | Cationic amino acid transporter 2 | [57] | -0.47[58] | 0.56[59] | 2.51[60] | -6.08[61] | -2.12[62] | 2.23[63] |
10 | SLC20A2 | Sodium-dependent phosphate transporter 2 | [64] | -0.68[65] | -1.20[66] | -0.86[67] | -2.68[68] | -2.98[69] | -1.84[70] |
11 | SRI | Sorcin | [71] | -7.57[72] | -9.27[73] | -1.96[74] | -0.75[75] | -0.72[76] | -1.93[77] |
12 | SLC20A1 | Sodium-dependent phosphate transporter 1 | [78] | 0.23[79] | 0.05[80] | -0.69[81] | -0.58[82] | 1.27[83] | -1.35[84] |
13 | SLC4A2 | Anion exchange protein 2 | [85] | 1.00[86] | 0.03[87] | 1.20[88] | 2.07[89] | 1.19[90] | -0.04[91] |
14 | SLC25A18 | Mitochondrial glutamate carrier 2 | [92] | -6.65[93] | -6.84[94] | -5.43[95] | -4.20[96] | -5.53[97] | 0.33[98] |
15 | SLC1A1 | Excitatory amino acid transporter 3 | [99] | -9.25[100] | -9.54[101] | -2.55[102] | -3.00[103] | -3.91[104] | 1.05[105] |
16 | SLC25A22 | Mitochondrial glutamate carrier 1 | [106] | -1.66[107] | -1.77[108] | -2.39[109] | -0.68[110] | -1.55[111] | -1.67[112] |
17 | SLC17A5 | Sialin | [113] | -0.55[114] | -0.81[115] | 0.27[116] | 0.00[117] | -0.85[118] | -0.69[119] |
18 | SLC15A4 | Solute carrier family 15 member 4 | [120] | -0.86[121] | -1.36[122] | -1.32[123] | -1.10[124] | -0.48[125] | -1.53[126] |
19 | SLC25A26 | S-adenosylmethionine mitochondrial carrier protein | [127] | -0.66[128] | -0.61[129] | -1.86[130] | -2.31[131] | -1.17[132] | -1.24[133] |
20 | SLC6A12 | Sodium- and chloride-dependent betaine transporter | [134] | -2.60[135] | -4.51[136] | -3.03[137] | -5.63[138] | -8.97[139] | -0.51[140] |
21 | SLC12A7 | Solute carrier family 12 member 7 | [141] | 0.07[142] | 0.33[143] | 0.34[144] | 1.26[145] | 0.04[146] | 1.03[147] |
22 | SLC1A5 | Neutral amino acid transporter B(0) | [148] | 2.95[149] | 1.91[150] | 2.04[151] | 2.93[152] | 2.16[153] | -2.99[154] |
23 | SLC38A1 | Sodium-coupled neutral amino acid transporter 1 | [155] | 1.62[156] | 2.17[157] | 2.38[158] | 1.29[159] | 2.96[160] | 0.51[161] |
24 | SLC12A4 | Solute carrier family 12 member 4 | [162] | 1.02[163] | 1.30[164] | -0.05[165] | -0.26[166] | 1.00[167] | -0.02[168] |
25 | SLC1A4 | Neutral amino acid transporter A | [169] | 1.39[170] | 0.59[171] | -1.65[172] | -0.17[173] | -1.47[174] | -0.77[175] |
26 | SLC7A9 | b(0,+)-type amino acid transporter 1 | [176] | -3.40[177] | -2.20[178] | -4.01[179] | -8.59[180] | -8.00[181] | -1.43[182] |
27 | SLC15A1 | Solute carrier family 15 member 1 | [183] | -4.46[184] | -5.62[185] | -2.12[186] | -5.61[187] | -6.14[188] | 0.25[189] |
28 | SLC25A29 | Mitochondrial basic amino acids transporter | [190] | -0.45[191] | -0.32[192] | -1.15[193] | 1.00[194] | 0.14[195] | -1.10[196] |
29 | SLC17A1 | Sodium-dependent phosphate transport protein 1 | [197] | -8.68[198] | -5.30[199] | -2.38[200] | [201] | -11.24[202] | -0.81[203] |
30 | SLC26A1 | Sulfate anion transporter 1 | [204] | -0.21[205] | 0.06[206] | 0.35[207] | -1.25[208] | -2.86[209] | 1.13[210] |
31 | SLC15A3 | Solute carrier family 15 member 3 | [211] | -4.43[212] | -8.05[213] | -8.50[214] | -1.70[215] | 0.04[216] | -1.48[217] |
32 | SLC6A6 | Sodium- and chloride-dependent taurine transporter | [218] | 1.89[219] | 0.46[220] | 2.56[221] | 3.24[222] | 0.33[223] | -1.29[224] |
33 | CTNS | Cystinosin | [225] | 0.37[226] | -0.23[227] | -0.05[228] | 0.26[229] | 0.65[230] | 0.02[231] |
34 | SLC36A4 | Proton-coupled amino acid transporter 4 | [232] | -0.97[233] | -2.73[234] | -1.21[235] | -0.19[236] | -0.15[237] | -0.56[238] |
35 | SLC7A1 | High affinity cationic amino acid transporter 1 | [239] | 3.05[240] | 2.08[241] | 1.78[242] | 2.64[243] | 2.79[244] | -1.45[245] |
36 | SLC7A6 | Y+L amino acid transporter 2 | [246] | 2.53[247] | 1.87[248] | 1.48[249] | 2.20[250] | 2.46[251] | -0.57[252] |
37 | SLC16A10 | Monocarboxylate transporter 10 | [253] | -1.54[254] | -8.19[255] | -0.36[256] | -6.21[257] | -5.09[258] | -0.52[259] |
38 | SLC1A2 | Excitatory amino acid transporter 2 | [260] | 0.94[261] | 1.50[262] | -4.77[263] | -3.75[264] | -6.06[265] | 3.50[266] |
39 | SLC26A6 | Solute carrier family 26 member 6 | [267] | 1.43[268] | 2.73[269] | 3.01[270] | 0.20[271] | 1.59[272] | -0.64[273] |
40 | SLC9A8 | Sodium/hydrogen exchanger 8 | [274] | 0.67[275] | 0.53[276] | 0.39[277] | 1.77[278] | 0.90[279] | 1.08[280] |
41 | SLC12A6 | Solute carrier family 12 member 6 | [281] | 0.91[282] | 1.22[283] | 0.80[284] | 1.56[285] | 1.43[286] | 0.55[287] |
42 | SLC3A1 | Neutral and basic amino acid transport protein rBAT | [288] | -7.08[289] | -6.60[290] | -0.07[291] | -4.29[292] | -8.01[293] | -0.79[294] |
43 | SLC9A7 | Sodium/hydrogen exchanger 7 | [295] | 0.85[296] | 0.35[297] | 0.45[298] | 1.89[299] | 1.04[300] | 1.61[301] |
44 | SLC9A6 | Sodium/hydrogen exchanger 6 | [302] | 0.11[303] | 0.11[304] | 1.38[305] | 1.87[306] | 1.91[307] | 0.44[308] |
45 | SLC26A11 | Sodium-independent sulfate anion transporter | [309] | 1.02[310] | 0.40[311] | 0.22[312] | 1.53[313] | 0.40[314] | -0.66[315] |
46 | SLC4A4 | Electrogenic sodium bicarbonate cotransporter 1 | [316] | -6.74[317] | -6.99[318] | 0.62[319] | 1.56[320] | -1.03[321] | 3.01[322] |
47 | SLC24A1 | Sodium/potassium/calcium exchanger 1 | [323] | -0.10[324] | 0.67[325] | 0.19[326] | -0.40[327] | -0.43[328] | -0.80[329] |
48 | SLC26A2 | Sulfate transporter | [330] | 0.63[331] | 0.74[332] | 0.67[333] | 2.37[334] | 3.69[335] | -0.03[336] |
49 | SLC38A5 | Sodium-coupled neutral amino acid transporter 5 | [337] | 2.22[338] | 2.03[339] | -5.11[340] | -4.16[341] | -4.34[342] | -4.37[343] |
50 | SLC7A7 | Y+L amino acid transporter 1 | [344] | 0.59[345] | -2.78[346] | 2.25[347] | -0.43[348] | 0.66[349] | -0.05[350] |
51 | SLC7A11 | Cystine/glutamate transporter | [351] | 2.00[352] | 2.61[353] | 2.67[354] | 4.61[355] | 3.46[356] | -2.08[357] |
52 | SLC4A7 | Sodium bicarbonate cotransporter 3 | [358] | 1.33[359] | 1.70[360] | 3.23[361] | 3.91[362] | 2.82[363] | 0.80[364] |
53 | AHCYL2 | Adenosylhomocysteinase 3 | [365] | 1.17[366] | 1.06[367] | 1.35[368] | 1.95[369] | 2.02[370] | 0.88[371] |
54 | SLC43A2 | Large neutral amino acids transporter small subunit 4 | [372] | 1.62[373] | 2.27[374] | 0.10[375] | 1.22[376] | 0.91[377] | -0.50[378] |
55 | SLC36A1 | Proton-coupled amino acid transporter 1 | [379] | 1.43[380] | 0.51[381] | 1.66[382] | 1.89[383] | 2.09[384] | 0.84[385] |
56 | SLC12A2 | Solute carrier family 12 member 2 | [386] | 0.83[387] | 0.46[388] | 2.60[389] | 2.97[390] | 2.65[391] | 2.58[392] |
57 | SLC7A8 | Large neutral amino acids transporter small subunit 2 | [393] | -3.98[394] | -6.35[395] | -1.35[396] | 0.34[397] | 2.68[398] | 1.11[399] |
58 | SLC7A3 | Cationic amino acid transporter 3 | [400] | [401] | [402] | [403] | -5.68[404] | -7.89[405] | [406] |
59 | SLC6A20 | Sodium- and chloride-dependent transporter XTRP3 | [407] | -3.26[408] | -2.05[409] | -1.97[410] | -2.55[411] | -3.02[412] | -2.46[413] |
60 | SLC9A1 | Sodium/hydrogen exchanger 1 | [414] | 2.33[415] | 1.00[416] | 0.08[417] | 3.86[418] | 3.81[419] | -0.32[420] |
61 | SLC5A5 | Sodium/iodide cotransporter | [421] | -2.79[422] | -2.19[423] | -1.44[424] | -1.91[425] | -2.50[426] | -2.80[427] |
62 | SLC4A1 | Band 3 anion transport protein | [428] | -2.12[429] | -2.58[430] | -2.92[431] | -2.54[432] | -2.67[433] | -0.33[434] |
63 | SLC4A5 | Electrogenic sodium bicarbonate cotransporter 4 | [435] | 2.12[436] | 3.19[437] | 2.28[438] | 0.95[439] | 2.21[440] | -0.95[441] |
64 | SLC1A3 | Excitatory amino acid transporter 1 | [442] | -4.16[443] | -2.76[444] | 3.93[445] | 4.12[446] | 3.91[447] | 1.66[448] |
65 | SLC34A1 | Sodium-dependent phosphate transport protein 2A | [449] | -6.92[450] | -4.88[451] | -1.69[452] | -4.32[453] | [454] | -1.09[455] |
66 | SLC34A3 | Sodium-dependent phosphate transport protein 2C | [456] | 0.37[457] | 2.17[458] | -3.52[459] | -2.31[460] | -1.98[461] | -2.91[462] |
67 | SLC9A9 | Sodium/hydrogen exchanger 9 | [463] | -7.47[464] | [465] | -6.11[466] | -0.06[467] | 2.25[468] | 3.43[469] |
68 | SLC9A2 | Sodium/hydrogen exchanger 2 | [470] | -4.39[471] | -4.75[472] | -3.79[473] | -1.75[474] | -2.80[475] | -1.96[476] |
69 | SLC36A2 | Proton-coupled amino acid transporter 2 | [477] | -0.60[478] | 0.43[479] | 0.44[480] | 0.13[481] | 0.25[482] | -1.06[483] |
70 | SLC24A4 | Sodium/potassium/calcium exchanger 4 | [484] | -0.01[485] | 0.87[486] | 0.50[487] | 0.96[488] | 0.54[489] | 1.49[490] |
71 | SLC5A12 | Sodium-coupled monocarboxylate transporter 2 | [491] | -4.80[492] | [493] | 4.46[494] | 3.84[495] | -1.44[496] | -1.68[497] |
72 | SLC1A7 | Excitatory amino acid transporter 5 | [498] | 1.00[499] | 1.26[500] | 4.88[501] | -0.36[502] | -1.84[503] | 1.04[504] |
73 | SLC9A3 | Sodium/hydrogen exchanger 3 | [505] | -0.83[506] | -1.68[507] | -0.42[508] | 0.26[509] | 2.07[510] | -1.50[511] |
74 | SLC15A2 | Solute carrier family 15 member 2 | [512] | 0.27[513] | 1.98[514] | 1.83[515] | 1.51[516] | 0.16[517] | 2.38[518] |
75 | SLC6A14 | Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) | 4.00[519] | 8.36[520] | 6.82[521] | 0.63[522] | -0.81[523] | -1.83[524] | |
76 | SLC1A6 | Excitatory amino acid transporter 4 | [525] | -3.82[526] | [527] | [528] | -4.00[529] | [530] | -1.79[531] |
77 | SLC4A3 | Anion exchange protein 3 | [532] | 2.80[533] | 0.07[534] | -2.56[535] | 4.88[536] | 5.00[537] | -1.36[538] |
78 | SLC9A4 | Sodium/hydrogen exchanger 4 | [539] | -0.54[540] | -0.87[541] | 0.99[542] | 1.86[543] | 1.13[544] | 2.77[545] |
79 | SLC26A4 | Pendrin | [546] | -0.63[547] | 0.60[548] | 0.61[549] | 0.82[550] | 1.75[551] | 2.31[552] |
80 | SLC4A10 | Sodium-driven chloride bicarbonate exchanger | [553] | [554] | [555] | -4.03[556] | -1.27[557] | -1.55[558] | 0.88[559] |
81 | SLC4A8 | Electroneutral sodium bicarbonate exchanger 1 | [560] | 1.49[561] | 2.59[562] | 2.01[563] | 5.70[564] | 5.19[565] | 2.18[566] |
82 | SLC8A1 | Sodium/calcium exchanger 1 | [567] | 0.88[568] | [569] | [570] | 4.49[571] | 2.49[572] | 6.55[573] |
83 | SLC24A2 | Sodium/potassium/calcium exchanger 2 | [574] | -2.01[575] | -2.43[576] | -2.82[577] | -4.73[578] | -4.79[579] | 3.00[580] |
84 | SLC8A3 | Sodium/calcium exchanger 3 | [581] | -1.21[582] | -3.41[583] | -4.04[584] | [585] | -2.73[586] | -0.43[587] |
85 | SLC26A3 | Chloride anion exchanger | [588] | -1.21[589] | 3.57[590] | 6.37[591] | -4.81[592] | -2.73[593] | 1.17[594] |
86 | SLC9A5 | Sodium/hydrogen exchanger 5 | [595] | 3.86[596] | 3.32[597] | 2.30[598] | 4.68[599] | 4.85[600] | 0.44[601] |
87 | SLC34A2 | Sodium-dependent phosphate transport protein 2B | [602] | 1.86[603] | -2.40[604] | 6.44[605] | -1.87[606] | 1.08[607] | 4.05[608] |
88 | SLC12A1 | Solute carrier family 12 member 1 | [609] | -2.49[610] | [611] | [612] | [613] | -1.49[614] | 1.98[615] |
89 | SLC12A5 | Solute carrier family 12 member 5 | [616] | 3.61[617] | 3.24[618] | 1.32[619] | 1.64[620] | 0.40[621] | 1.40[622] |
90 | SLC8A2 | Sodium/calcium exchanger 2 | [623] | 0.34[624] | -0.54[625] | -0.68[626] | 0.76[627] | -0.68[628] | -1.05[629] |
91 | SLC6A19 | Sodium-dependent neutral amino acid transporter B(0)AT1 | [630] | 0.82[631] | -1.11[632] | 6.37[633] | -2.48[634] | -1.66[635] | 4.50[636] |
92 | SLC26A7 | Anion exchange transporter | [637] | -1.58[638] | 0.42[639] | 5.07[640] | -0.37[641] | 1.70[642] | 2.17[643] |
93 | SLC17A7 | Vesicular glutamate transporter 1 | [644] | 2.37[645] | 2.46[646] | 2.29[647] | 3.82[648] | 2.19[649] | -0.04[650] |
94 | SLC6A15 | Sodium-dependent neutral amino acid transporter B(0)AT2 | [651] | -1.21[652] | [653] | -2.34[654] | 5.47[655] | 9.27[656] | 1.39[657] |
95 | SLC17A8 | Vesicular glutamate transporter 3 | [658] | 4.50[659] | -0.21[660] | 5.30[661] | 0.16[662] | -0.50[663] | 4.16[664] |
96 | SLC24A3 | Sodium/potassium/calcium exchanger 3 | [665] | -2.58[666] | -1.89[667] | -1.45[668] | 3.15[669] | 9.22[670] | 4.49[671] |
97 | SLC7A10 | Asc-type amino acid transporter 1 | [672] | [673] | [674] | [675] | [676] | [677] | [678] |
98 | SLC17A6 | Vesicular glutamate transporter 2 | [679] | [680] | [681] | [682] | [683] | [684] | [685] |
99 | SLC5A8 | Sodium-coupled monocarboxylate transporter 1 | [686] | [687] | [688] | [689] | [690] | [691] | [692] |
100 | SLC24A5 | Sodium/potassium/calcium exchanger 5 | [693] | [694] | [695] | [696] | [697] | [698] | [699] |
101 | SLC8B1 | Mitochondrial sodium/calcium exchanger protein | [700] | [701] | [702] | [703] | [704] | [705] | [706] |
102 | SLC26A9 | Solute carrier family 26 member 9 | [707] | [708] | [709] | [710] | [711] | [712] | [713] |
103 | SLC12A3 | Solute carrier family 12 member 3 | [714] | [715] | [716] | [717] | [718] | [719] | [720] |
104 | SLC32A1 | Vesicular inhibitory amino acid transporter | [721] | [722] | [723] | [724] | [725] | [726] | [727] |
105 | SLC6A18 | Sodium-dependent neutral amino acid transporter B(0)AT3 | [728] | [729] | [730] | [731] | [732] | [733] | [734] |
106 | SLC4A9 | Anion exchange protein 4 | [735] | [736] | [737] | [738] | [739] | [740] | [741] |