REACTOME_TRANSLESION_SYNTHESIS_BY_POLK Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 UBB Polyubiquitin-B [1] -0.40[2] -0.70[3] -0.66[4] -0.60[5] -0.46[6] 0.04[7]
2 RPS27A Ubiquitin-40S ribosomal protein S27a [8] [9] [10] [11] [12] [13] [14]
3 UBC Polyubiquitin-C [15] 0.04[16] 0.05[17] -0.30[18] 0.26[19] -0.08[20] 0.49[21]
4 UBA52 Ubiquitin-60S ribosomal protein L40 [22] 2.48[23] 2.28[24] 3.21[25] 1.66[26] 2.14[27] 1.26[28]
5 PCNA Proliferating cell nuclear antigen [29] 2.69[30] 2.57[31] 1.05[32] 1.97[33] 1.92[34] -1.16[35]
6 RPA2 Replication protein A 32 kDa subunit [36] 0.34[37] 0.31[38] 0.76[39] 1.44[40] 1.19[41] -0.49[42]
7 MAD2L2 Mitotic spindle assembly checkpoint protein MAD2B [43] 0.27[44] 1.58[45] 0.19[46] 0.51[47] 0.40[48] 0.49[49]
8 RFC4 Replication factor C subunit 4 [50] 0.83[51] 1.35[52] 1.82[53] 1.22[54] 2.23[55] -0.84[56]
9 RFC1 Replication factor C subunit 1 [57] 1.94[58] 3.12[59] 3.40[60] 2.51[61] 3.02[62] 2.69[63]
10 RFC2 Replication factor C subunit 2 [64] 1.53[65] 1.29[66] 1.22[67] 2.36[68] 2.50[69] 1.14[70]
11 RPA1 Replication protein A 70 kDa DNA-binding subunit [71] 3.11[72] 2.74[73] 2.91[74] 4.04[75] 3.73[76] 1.91[77]
12 RPA3 Replication protein A 14 kDa subunit [78] 1.43[79] 2.13[80] 2.74[81] 1.28[82] 1.24[83] 1.22[84]
13 RFC5 Replication factor C subunit 5 [85] 1.93[86] 2.28[87] 2.37[88] 2.45[89] 2.66[90] 1.03[91]
14 RFC3 Replication factor C subunit 3 [92] 2.97[93] 3.73[94] 3.77[95] 3.44[96] 3.71[97] 1.04[98]
15 REV1 DNA repair protein REV1 [99] 3.24[100] 4.34[101] 3.51[102] 4.02[103] 3.66[104] 3.72[105]
16 POLK DNA polymerase kappa [106] 0.96[107] 2.33[108] 2.47[109] 4.02[110] 3.42[111] 4.01[112]
17 REV3L DNA polymerase zeta catalytic subunit [113] 4.21[114] 5.67[115] 4.17[116] 5.19[117] 5.00[118] 6.38[119]
[1]
ref_hepatocyte UBB
Mean 764
Standard deviation 4.8e+02
Values 3.8e+02 3.5e+02 5.3e+02 1.2e+03 1.3e+03
[2]
HepG2 UBB
Mean 368
Standard deviation 39
Values 4e+02 3.4e+02
[3]
HepG2.C3A UBB
Mean 285
Standard deviation 14
Values 2.8e+02 3e+02
[4]
HuH.7 UBB
Mean 304
Standard deviation 40
Values 2.9e+02 2.7e+02 3.5e+02
[5]
SNU475 UBB
Mean 204
Standard deviation 3.3
Values 2.1e+02 2e+02
[6]
THLE UBB
Mean 315
Standard deviation 34
Values 2.9e+02 3.4e+02
[7]
liver UBB
Mean 296
Standard deviation 1.3e+02
Values 4.3e+02 2.1e+02 3.9e+02 1.5e+02
[8]
ref_hepatocyte RPS27A
Mean 499
Standard deviation 2.2e+02
Values 6.6e+02 6.1e+02 1.7e+02 6.8e+02 3.8e+02
[9]
HepG2 RPS27A
Missing
[10]
HepG2.C3A RPS27A
Missing
[11]
HuH.7 RPS27A
Missing
[12]
SNU475 RPS27A
Missing
[13]
THLE RPS27A
Missing
[14]
liver RPS27A
Missing
[15]
ref_hepatocyte UBC
Mean 480
Standard deviation 2.8e+02
Values 1.8e+02 3.5e+02 9.1e+02 5.8e+02 3.8e+02
[16]
HepG2 UBC
Mean 314
Standard deviation 38
Values 3.4e+02 2.9e+02
[17]
HepG2.C3A UBC
Mean 302
Standard deviation 41
Values 3.3e+02 2.7e+02
[18]
HuH.7 UBC
Mean 246
Standard deviation 64
Values 2.4e+02 3.1e+02 1.9e+02
[19]
SNU475 UBC
Mean 232
Standard deviation 63
Values 2.8e+02 1.9e+02
[20]
THLE UBC
Mean 257
Standard deviation 41
Values 2.3e+02 2.9e+02
[21]
liver UBC
Mean 254
Standard deviation 78
Values 2.2e+02 3.1e+02 3.3e+02 1.6e+02
[22]
ref_hepatocyte UBA52
Mean 57.3
Standard deviation 43
Values 14 23 49 1.2e+02 81
[23]
HepG2 UBA52
Mean 203
Standard deviation 20
Values 2.2e+02 1.9e+02
[24]
HepG2.C3A UBA52
Mean 169
Standard deviation 3.3
Values 1.7e+02 1.7e+02
[25]
HuH.7 UBA52
Mean 334
Standard deviation 46
Values 3.4e+02 2.8e+02 3.7e+02
[26]
SNU475 UBA52
Mean 72.9
Standard deviation 11
Values 65 81
[27]
THLE UBA52
Mean 144
Standard deviation 15
Values 1.3e+02 1.5e+02
[28]
liver UBA52
Mean 51.7
Standard deviation 26
Values 79 32 68 28
[29]
ref_hepatocyte PCNA
Mean 36
Standard deviation 33
Values 92 37 14 19 17
[30]
HepG2 PCNA
Mean 147
Standard deviation 54
Values 1.1e+02 1.9e+02
[31]
HepG2.C3A PCNA
Mean 130
Standard deviation 86
Values 69 1.9e+02
[32]
HuH.7 PCNA
Mean 46.8
Standard deviation 33
Values 53 10 76
[33]
SNU475 PCNA
Mean 56.8
Standard deviation 7.7
Values 51 62
[34]
THLE PCNA
Mean 77.4
Standard deviation 13
Values 68 86
[35]
liver PCNA
Mean 6.07
Standard deviation 2.5
Values 7.3 5.2 8.8 3
[36]
ref_hepatocyte RPA2
Mean 23.6
Standard deviation 12
Values 23 41 28 15 11
[37]
HepG2 RPA2
Mean 19
Standard deviation 3.9
Values 16 22
[38]
HepG2.C3A RPA2
Mean 17.8
Standard deviation 8.2
Values 12 24
[39]
HuH.7 RPA2
Mean 25.2
Standard deviation 11
Values 27 14 35
[40]
SNU475 RPA2
Mean 25.9
Standard deviation 7.9
Values 20 31
[41]
THLE RPA2
Mean 30.6
Standard deviation 2.7
Values 29 33
[42]
liver RPA2
Mean 6.36
Standard deviation 3.6
Values 6.9 4.2 11 3.2
[43]
ref_hepatocyte MAD2L2
Mean 23.4
Standard deviation 6.1
Values 16 26 23 32 20
[44]
HepG2 MAD2L2
Mean 17.9
Standard deviation 0.58
Values 18 17
[45]
HepG2.C3A MAD2L2
Mean 42.5
Standard deviation 1.7
Values 41 44
[46]
HuH.7 MAD2L2
Mean 16.8
Standard deviation 3.2
Values 17 13 20
[47]
SNU475 MAD2L2
Mean 13.5
Standard deviation 1.8
Values 12 15
[48]
THLE MAD2L2
Mean 17.6
Standard deviation 0.71
Values 18 17
[49]
liver MAD2L2
Mean 12.4
Standard deviation 8.8
Values 20 5.2 20 4.5
[50]
ref_hepatocyte RFC4
Mean 11
Standard deviation 7.9
Values 17 21 9.8 4.7 2.4
[51]
HepG2 RFC4
Mean 12.4
Standard deviation 2.7
Values 10 14
[52]
HepG2.C3A RFC4
Mean 17
Standard deviation 7.7
Values 12 22
[53]
HuH.7 RFC4
Mean 24.4
Standard deviation 12
Values 26 12 35
[54]
SNU475 RFC4
Mean 10.3
Standard deviation 3.5
Values 7.8 13
[55]
THLE RFC4
Mean 29.1
Standard deviation 0.079
Values 29 29
[56]
liver RFC4
Mean 2.31
Standard deviation 1.2
Values 2.3 1.9 4 1
[57]
ref_hepatocyte RFC1
Mean 9.26
Standard deviation 5.4
Values 15 15 7.1 4.1 5
[58]
HepG2 RFC1
Mean 22.5
Standard deviation 11
Values 15 30
[59]
HepG2.C3A RFC1
Mean 49.1
Standard deviation 4.6
Values 46 52
[60]
HuH.7 RFC1
Mean 61.4
Standard deviation 8.8
Values 66 67 51
[61]
SNU475 RFC1
Mean 21.2
Standard deviation 2
Values 20 23
[62]
THLE RFC1
Mean 42.7
Standard deviation 3.9
Values 45 40
[63]
liver RFC1
Mean 22.6
Standard deviation 3.4
Values 24 26 18 23
[64]
ref_hepatocyte RFC2
Mean 8.95
Standard deviation 3.2
Values 7.3 13 6.2 11 6.5
[65]
HepG2 RFC2
Mean 16.5
Standard deviation 2.8
Values 14 18
[66]
HepG2.C3A RFC2
Mean 13.3
Standard deviation 5.7
Values 9.3 17
[67]
HuH.7 RFC2
Mean 13.1
Standard deviation 6.2
Values 15 6.1 18
[68]
SNU475 RFC2
Mean 18.6
Standard deviation 4.4
Values 16 22
[69]
THLE RFC2
Mean 28.7
Standard deviation 3.4
Values 26 31
[70]
liver RFC2
Mean 7.44
Standard deviation 4.1
Values 10 4.9 11 3.1
[71]
ref_hepatocyte RPA1
Mean 8.25
Standard deviation 3.9
Values 9.2 15 5.5 5.3 6.7
[72]
HepG2 RPA1
Mean 45.3
Standard deviation 8.3
Values 39 51
[73]
HepG2.C3A RPA1
Mean 33.6
Standard deviation 11
Values 26 41
[74]
HuH.7 RPA1
Mean 39
Standard deviation 14
Values 47 23 48
[75]
SNU475 RPA1
Mean 54.6
Standard deviation 1
Values 55 54
[76]
THLE RPA1
Mean 62.1
Standard deviation 11
Values 54 70
[77]
liver RPA1
Mean 11.7
Standard deviation 1.8
Values 12 12 14 9.5
[78]
ref_hepatocyte RPA3
Mean 8.22
Standard deviation 4.8
Values 6.2 7.6 1.9 11 15
[79]
HepG2 RPA3
Mean 14.1
Standard deviation 4
Values 11 17
[80]
HepG2.C3A RPA3
Mean 21.8
Standard deviation 13
Values 13 31
[81]
HuH.7 RPA3
Mean 34.5
Standard deviation 16
Values 35 18 50
[82]
SNU475 RPA3
Mean 8.05
Standard deviation 1.5
Values 9.1 7
[83]
THLE RPA3
Mean 11
Standard deviation 2.9
Values 8.9 13
[84]
liver RPA3
Mean 7.22
Standard deviation 6.1
Values 13 2.4 12 1.4
[85]
ref_hepatocyte RFC5
Mean 5.54
Standard deviation 4.9
Values 13 7.4 0.42 3.6 3.2
[86]
HepG2 RFC5
Mean 13.4
Standard deviation 5.4
Values 9.6 17
[87]
HepG2.C3A RFC5
Mean 16.4
Standard deviation 10
Values 9 24
[88]
HuH.7 RFC5
Mean 18.1
Standard deviation 6.8
Values 23 10 21
[89]
SNU475 RFC5
Mean 12.2
Standard deviation 2.4
Values 11 14
[90]
THLE RFC5
Mean 19.8
Standard deviation 2.4
Values 18 22
[91]
liver RFC5
Mean 4.29
Standard deviation 1.7
Values 4.9 3.5 6.3 2.5
[92]
ref_hepatocyte RFC3
Mean 3.17
Standard deviation 3.1
Values 6.3 6.7 1.4 0.35 1.1
[93]
HepG2 RFC3
Mean 15.8
Standard deviation 7.8
Values 10 21
[94]
HepG2.C3A RFC3
Mean 25.6
Standard deviation 17
Values 14 37
[95]
HuH.7 RFC3
Mean 27.1
Standard deviation 12
Values 35 14 33
[96]
SNU475 RFC3
Mean 13.8
Standard deviation 3.5
Values 11 16
[97]
THLE RFC3
Mean 23.5
Standard deviation 5.4
Values 20 27
[98]
liver RFC3
Mean 2.46
Standard deviation 0.85
Values 2 2.9 3.4 1.5
[99]
ref_hepatocyte REV1
Mean 2.22
Standard deviation 1.2
Values 4.1 2.1 0.84 2.2 1.9
[100]
HepG2 REV1
Mean 13.3
Standard deviation 2.7
Values 11 15
[101]
HepG2.C3A REV1
Mean 27.3
Standard deviation 3.9
Values 30 25
[102]
HuH.7 REV1
Mean 15.9
Standard deviation 2
Values 16 14 18
[103]
SNU475 REV1
Mean 14.5
Standard deviation 0.93
Values 15 14
[104]
THLE REV1
Mean 15.9
Standard deviation 0.38
Values 16 16
[105]
liver REV1
Mean 11.1
Standard deviation 2.7
Values 11 12 7.4 14
[106]
ref_hepatocyte POLK
Mean 2.2
Standard deviation 1.6
Values 1 4.7 2.2 0.59 2.5
[107]
HepG2 POLK
Mean 2.71
Standard deviation 0.4
Values 2.4 3
[108]
HepG2.C3A POLK
Mean 6.72
Standard deviation 1.5
Values 5.7 7.8
[109]
HuH.7 POLK
Mean 7.69
Standard deviation 1.2
Values 8.1 8.7 6.3
[110]
SNU475 POLK
Mean 14.4
Standard deviation 1
Values 15 14
[111]
THLE POLK
Mean 13.4
Standard deviation 2.8
Values 15 11
[112]
liver POLK
Mean 13.4
Standard deviation 3.4
Values 11 18 11 13
[113]
ref_hepatocyte REV3L
Mean 0.797
Standard deviation 0.43
Values 1.5 0.87 0.81 0.35 0.49
[114]
HepG2 REV3L
Mean 9.34
Standard deviation 3.8
Values 6.6 12
[115]
HepG2.C3A REV3L
Mean 24.6
Standard deviation 4.9
Values 21 28
[116]
HuH.7 REV3L
Mean 9.03
Standard deviation 2.1
Values 11 9.5 6.7
[117]
SNU475 REV3L
Mean 11.7
Standard deviation 0.59
Values 12 11
[118]
THLE REV3L
Mean 14.5
Standard deviation 4.7
Values 18 11
[119]
liver REV3L
Mean 25
Standard deviation 9.5
Values 21 36 14 28