REACTOME_TRANSCRIPTION_OF_E2F_TARGETS_UNDER_NEGATIVE_CONTROL_BY_DREAM_COMPLEX Return to index
Order Gene Description ref_hepatocyte HepG2 HepG2.C3A HuH.7 SNU475 THLE liver
1 PCNA Proliferating cell nuclear antigen [1] -0.04[2] -0.28[3] -1.63[4] -0.91[5] -1.09[6] -2.64[7]
2 MYC Myc proto-oncogene protein [8] -0.50[9] -1.06[10] -3.03[11] -3.48[12] -1.57[13] -1.57[14]
3 HDAC1 Histone deacetylase 1 [15] -0.42[16] -0.63[17] 0.11[18] -0.05[19] -0.73[20] -0.03[21]
4 TFDP1 Transcription factor Dp-1 [22] -0.27[23] -1.16[24] -1.03[25] -0.09[26] 0.03[27] -0.71[28]
5 MAX Protein max [29] -1.87[30] -2.11[31] -2.74[32] -1.46[33] -1.39[34] -0.81[35]
6 E2F4 Transcription factor E2F4 [36] 0.20[37] 0.09[38] -0.83[39] -0.27[40] -0.74[41] 0.19[42]
7 RBBP4 Histone-binding protein RBBP4 [43] 1.01[44] 0.90[45] 0.78[46] 0.99[47] 0.91[48] 1.93[49]
8 RBL2 Retinoblastoma-like protein 2 [50] -0.09[51] 0.53[52] 0.64[53] 0.54[54] -0.22[55] 2.57[56]
9 TOP2A DNA topoisomerase 2-alpha [57] 1.60[58] 2.43[59] 3.17[60] 2.74[61] 3.04[62] 0.05[63]
10 LIN37 Protein lin-37 homolog [64] -2.94[65] -2.72[66] -2.35[67] -2.36[68] -2.57[69] -1.29[70]
11 CDC6 Cell division control protein 6 homolog [71] 0.93[72] 0.27[73] 0.94[74] 0.87[75] 0.68[76] -1.63[77]
12 LIN52 Protein lin-52 homolog [78] -0.96[79] -0.42[80] -0.91[81] -1.79[82] -1.14[83] 0.09[84]
13 E2F1 Transcription factor E2F1 [85] 1.02[86] 0.65[87] 0.83[88] 1.17[89] 1.15[90] -3.18[91]
14 CDC25A M-phase inducer phosphatase 1 [92] 0.50[93] 0.91[94] 1.31[95] -0.35[96] 0.65[97] -2.23[98]
15 TFDP2 Transcription factor Dp-2 [99] 0.98[100] 1.44[101] 1.52[102] 1.69[103] 1.46[104] 2.78[105]
16 LIN54 Protein lin-54 homolog [106] 0.50[107] 1.79[108] 0.81[109] 0.42[110] 0.81[111] 2.24[112]
17 E2F5 Transcription factor E2F5 [113] 0.59[114] 1.33[115] 1.79[116] -0.67[117] -2.67[118] -1.25[119]
18 RBL1 Retinoblastoma-like protein 1 [120] 0.85[121] 1.49[122] 0.18[123] 2.12[124] 1.99[125] 1.11[126]
19 LIN9 Protein lin-9 homolog [127] 0.09[128] 1.19[129] 1.97[130] 2.21[131] 1.24[132] 0.42[133]
[1]
ref_hepatocyte PCNA
Mean 36
Standard deviation 33
Values 92 37 14 19 17
[2]
HepG2 PCNA
Mean 147
Standard deviation 54
Values 1.1e+02 1.9e+02
[3]
HepG2.C3A PCNA
Mean 130
Standard deviation 86
Values 69 1.9e+02
[4]
HuH.7 PCNA
Mean 46.8
Standard deviation 33
Values 53 10 76
[5]
SNU475 PCNA
Mean 56.8
Standard deviation 7.7
Values 51 62
[6]
THLE PCNA
Mean 77.4
Standard deviation 13
Values 68 86
[7]
liver PCNA
Mean 6.07
Standard deviation 2.5
Values 7.3 5.2 8.8 3
[8]
ref_hepatocyte MYC
Mean 29.9
Standard deviation 34
Values 15 20 89 23 1.4
[9]
HepG2 MYC
Mean 88.8
Standard deviation 53
Values 1.3e+02 52
[10]
HepG2.C3A MYC
Mean 62.6
Standard deviation 15
Values 73 52
[11]
HuH.7 MYC
Mean 14.7
Standard deviation 2.6
Values 13 18 14
[12]
SNU475 MYC
Mean 7.93
Standard deviation 1.4
Values 6.9 8.9
[13]
THLE MYC
Mean 46
Standard deviation 10
Values 39 53
[14]
liver MYC
Mean 10.6
Standard deviation 6
Values 18 5.9 13 5.5
[15]
ref_hepatocyte HDAC1
Mean 20.8
Standard deviation 4.1
Values 22 28 19 18 18
[16]
HepG2 HDAC1
Mean 65.4
Standard deviation 11
Values 73 58
[17]
HepG2.C3A HDAC1
Mean 58.9
Standard deviation 2.3
Values 57 60
[18]
HuH.7 HDAC1
Mean 90.9
Standard deviation 22
Values 94 68 1.1e+02
[19]
SNU475 HDAC1
Mean 59.8
Standard deviation 8
Values 65 54
[20]
THLE HDAC1
Mean 57.8
Standard deviation 6.8
Values 53 63
[21]
liver HDAC1
Mean 21.5
Standard deviation 6.8
Values 25 18 29 14
[22]
ref_hepatocyte TFDP1
Mean 14.3
Standard deviation 8.3
Values 23 24 5.8 10 9.4
[23]
HepG2 TFDP1
Mean 50.2
Standard deviation 7.6
Values 45 56
[24]
HepG2.C3A TFDP1
Mean 28.1
Standard deviation 13
Values 19 38
[25]
HuH.7 TFDP1
Mean 28.3
Standard deviation 13
Values 35 13 37
[26]
SNU475 TFDP1
Mean 40
Standard deviation 3.2
Values 42 38
[27]
THLE TFDP1
Mean 67
Standard deviation 13
Values 58 76
[28]
liver TFDP1
Mean 9.23
Standard deviation 0.4
Values 9.3 9.6 8.7 9.3
[29]
ref_hepatocyte MAX
Mean 12.4
Standard deviation 7.6
Values 8.7 7.7 26 12 8.2
[30]
HepG2 MAX
Mean 14.3
Standard deviation 0.86
Values 15 14
[31]
HepG2.C3A MAX
Mean 12.5
Standard deviation 3.2
Values 15 10
[32]
HuH.7 MAX
Mean 7.51
Standard deviation 0.49
Values 7.3 7.1 8.1
[33]
SNU475 MAX
Mean 13.4
Standard deviation 1.2
Values 14 13
[34]
THLE MAX
Mean 21.7
Standard deviation 2.5
Values 20 23
[35]
liver MAX
Mean 7.46
Standard deviation 4.5
Values 10 3.5 12 3.7
[36]
ref_hepatocyte E2F4
Mean 10.4
Standard deviation 9.6
Values 7.5 5.1 27 7.8 4.3
[37]
HepG2 E2F4
Mean 50.4
Standard deviation 3
Values 48 53
[38]
HepG2.C3A E2F4
Mean 48.5
Standard deviation 4.6
Values 45 52
[39]
HuH.7 E2F4
Mean 23.7
Standard deviation 7.6
Values 26 15 30
[40]
SNU475 E2F4
Mean 25.6
Standard deviation 0.41
Values 26 25
[41]
THLE E2F4
Mean 28.5
Standard deviation 3.3
Values 31 26
[42]
liver E2F4
Mean 12.5
Standard deviation 3.7
Values 14 8.5 17 11
[43]
ref_hepatocyte RBBP4
Mean 7.41
Standard deviation 4.4
Values 15 5.5 3.7 7.2 5.6
[44]
HepG2 RBBP4
Mean 62.8
Standard deviation 14
Values 53 73
[45]
HepG2.C3A RBBP4
Mean 60.7
Standard deviation 2
Values 59 62
[46]
HuH.7 RBBP4
Mean 51.2
Standard deviation 12
Values 58 38 58
[47]
SNU475 RBBP4
Mean 43.5
Standard deviation 3.5
Values 46 41
[48]
THLE RBBP4
Mean 63.8
Standard deviation 8.4
Values 58 70
[49]
liver RBBP4
Mean 29.8
Standard deviation 6
Values 24 30 38 27
[50]
ref_hepatocyte RBL2
Mean 6.31
Standard deviation 3.1
Values 6.8 4 4.2 5 12
[51]
HepG2 RBL2
Mean 24.9
Standard deviation 4.6
Values 22 28
[52]
HepG2.C3A RBL2
Mean 39.8
Standard deviation 0.53
Values 39 40
[53]
HuH.7 RBL2
Mean 39.7
Standard deviation 1.6
Values 42 39 39
[54]
SNU475 RBL2
Mean 27.1
Standard deviation 11
Values 35 19
[55]
THLE RBL2
Mean 24.9
Standard deviation 0.58
Values 25 24
[56]
liver RBL2
Mean 39.5
Standard deviation 5.1
Values 37 41 34 46
[57]
ref_hepatocyte TOP2A
Mean 6.23
Standard deviation 8
Values 19 9.5 0.84 0.78 1.1
[58]
HepG2 TOP2A
Mean 79.3
Standard deviation 35
Values 54 1e+02
[59]
HepG2.C3A TOP2A
Mean 147
Standard deviation 82
Values 89 2e+02
[60]
HuH.7 TOP2A
Mean 226
Standard deviation 93
Values 3e+02 1.2e+02 2.6e+02
[61]
SNU475 TOP2A
Mean 123
Standard deviation 22
Values 1.1e+02 1.4e+02
[62]
THLE TOP2A
Mean 235
Standard deviation 14
Values 2.5e+02 2.2e+02
[63]
liver TOP2A
Mean 6.81
Standard deviation 6.8
Values 2 14 11 0.17
[64]
ref_hepatocyte LIN37
Mean 5.39
Standard deviation 4.7
Values 1.7 4.1 13 5.4 2.4
[65]
HepG2 LIN37
Mean 2.96
Standard deviation 0.14
Values 3.1 2.9
[66]
HepG2.C3A LIN37
Mean 3.59
Standard deviation 1.1
Values 4.3 2.8
[67]
HuH.7 LIN37
Mean 4.28
Standard deviation 0.46
Values 4.4 3.8 4.7
[68]
SNU475 LIN37
Mean 3.12
Standard deviation 0.33
Values 2.9 3.4
[69]
THLE LIN37
Mean 4.15
Standard deviation 0.017
Values 4.1 4.2
[70]
liver LIN37
Mean 2.33
Standard deviation 2
Values 4.7 0.53 3.3 0.79
[71]
ref_hepatocyte CDC6
Mean 4.53
Standard deviation 4.6
Values 11 8.2 1.9 1.2 0.8
[72]
HepG2 CDC6
Mean 36.3
Standard deviation 14
Values 26 46
[73]
HepG2.C3A CDC6
Mean 24
Standard deviation 17
Values 12 36
[74]
HuH.7 CDC6
Mean 35
Standard deviation 18
Values 43 15 47
[75]
SNU475 CDC6
Mean 24.6
Standard deviation 9.5
Values 18 31
[76]
THLE CDC6
Mean 33.3
Standard deviation 6.1
Values 29 38
[77]
liver CDC6
Mean 1.54
Standard deviation 0.85
Values 0.42 2.4 2 1.4
[78]
ref_hepatocyte LIN52
Mean 2.62
Standard deviation 1.5
Values 3.9 1.9 4.7 1.4 1.2
[79]
HepG2 LIN52
Mean 5.68
Standard deviation 1.2
Values 4.8 6.6
[80]
HepG2.C3A LIN52
Mean 8.55
Standard deviation 4.3
Values 5.5 12
[81]
HuH.7 LIN52
Mean 5.62
Standard deviation 0.72
Values 6.1 4.8 6
[82]
SNU475 LIN52
Mean 2.24
Standard deviation 0.051
Values 2.3 2.2
[83]
THLE LIN52
Mean 5.44
Standard deviation 0.89
Values 4.8 6.1
[84]
liver LIN52
Mean 2.93
Standard deviation 0.97
Values 2.3 3.1 4.2 2.1
[85]
ref_hepatocyte E2F1
Mean 2.5
Standard deviation 3.1
Values 7.9 2.2 0.64 1.2 0.54
[86]
HepG2 E2F1
Mean 21.3
Standard deviation 1.8
Values 20 23
[87]
HepG2.C3A E2F1
Mean 17.2
Standard deviation 4.9
Values 14 21
[88]
HuH.7 E2F1
Mean 18
Standard deviation 12
Values 21 5.1 28
[89]
SNU475 E2F1
Mean 16.7
Standard deviation 4.8
Values 13 20
[90]
THLE E2F1
Mean 25.4
Standard deviation 2.4
Values 24 27
[91]
liver E2F1
Mean 0.29
Standard deviation 0.19
Values 0.12 0.49 0.41 0.15
[92]
ref_hepatocyte CDC25A
Mean 2.04
Standard deviation 2.5
Values 6.2 2.3 1 0.26 0.37
[93]
HepG2 CDC25A
Mean 12.1
Standard deviation 2.6
Values 10 14
[94]
HepG2.C3A CDC25A
Mean 16.8
Standard deviation 9.8
Values 9.8 24
[95]
HuH.7 CDC25A
Mean 20.5
Standard deviation 10
Values 26 8.6 27
[96]
SNU475 CDC25A
Mean 4.76
Standard deviation 2.1
Values 3.3 6.2
[97]
THLE CDC25A
Mean 14.6
Standard deviation 2.2
Values 13 16
[98]
liver CDC25A
Mean 0.459
Standard deviation 0.38
Values 0.33 1 0.28 0.2
[99]
ref_hepatocyte TFDP2
Mean 1.97
Standard deviation 0.83
Values 3.4 2.1 1.3 1.4 1.7
[100]
HepG2 TFDP2
Mean 16.3
Standard deviation 2.5
Values 15 18
[101]
HepG2.C3A TFDP2
Mean 23.5
Standard deviation 2.1
Values 22 25
[102]
HuH.7 TFDP2
Mean 22.8
Standard deviation 3.1
Values 26 20 22
[103]
SNU475 TFDP2
Mean 18.9
Standard deviation 4.1
Values 22 16
[104]
THLE TFDP2
Mean 24.9
Standard deviation 1.2
Values 24 26
[105]
liver TFDP2
Mean 14.3
Standard deviation 3.4
Values 17 14 9.6 16
[106]
ref_hepatocyte LIN54
Mean 1.42
Standard deviation 0.64
Values 2.3 1.7 0.89 0.74 1.4
[107]
HepG2 LIN54
Mean 8.41
Standard deviation 4.8
Values 5 12
[108]
HepG2.C3A LIN54
Mean 21.5
Standard deviation 4.2
Values 18 24
[109]
HuH.7 LIN54
Mean 10
Standard deviation 0.65
Values 11 10 9.3
[110]
SNU475 LIN54
Mean 5.61
Standard deviation 0.82
Values 5 6.2
[111]
THLE LIN54
Mean 11.4
Standard deviation 1.1
Values 11 12
[112]
liver LIN54
Mean 7.02
Standard deviation 1.6
Values 4.8 8.7 6.9 7.7
[113]
ref_hepatocyte E2F5
Mean 1
Standard deviation 0.88
Values 1.9 0.45 0 1.9 0.74
[114]
HepG2 E2F5
Mean 6.38
Standard deviation 0.95
Values 7.1 5.7
[115]
HepG2.C3A E2F5
Mean 11.1
Standard deviation 0.8
Values 11 12
[116]
HuH.7 E2F5
Mean 14
Standard deviation 0.82
Values 13 14 15
[117]
SNU475 E2F5
Mean 1.88
Standard deviation 0.29
Values 2.1 1.7
[118]
THLE E2F5
Mean 0.724
Standard deviation 0.11
Values 0.8 0.65
[119]
liver E2F5
Mean 0.444
Standard deviation 0.12
Values 0.54 0.54 0.31 0.38
[120]
ref_hepatocyte RBL1
Mean 0.836
Standard deviation 0.94
Values 2.4 0.96 0.44 0.14 0.22
[121]
HepG2 RBL1
Mean 6.34
Standard deviation 2.4
Values 4.6 8
[122]
HepG2.C3A RBL1
Mean 10.3
Standard deviation 8.7
Values 4.2 16
[123]
HuH.7 RBL1
Mean 3.82
Standard deviation 1.7
Values 5.6 2.2 3.6
[124]
SNU475 RBL1
Mean 10.8
Standard deviation 2.6
Values 8.9 13
[125]
THLE RBL1
Mean 15.2
Standard deviation 0.62
Values 15 16
[126]
liver RBL1
Mean 1.9
Standard deviation 0.74
Values 1.3 2.9 1.5 2
[127]
ref_hepatocyte LIN9
Mean 0.607
Standard deviation 0.55
Values 1.4 0.95 0.2 0.16 0.31
[128]
HepG2 LIN9
Mean 2.71
Standard deviation 1.1
Values 1.9 3.5
[129]
HepG2.C3A LIN9
Mean 6.07
Standard deviation 4.2
Values 3.1 9.1
[130]
HuH.7 LIN9
Mean 9.59
Standard deviation 2.4
Values 11 6.8 11
[131]
SNU475 LIN9
Mean 8.31
Standard deviation 1.7
Values 7.1 9.5
[132]
THLE LIN9
Mean 6.58
Standard deviation 0.93
Values 7.2 5.9
[133]
liver LIN9
Mean 0.855
Standard deviation 0.079
Values 0.87 0.88 0.92 0.74