REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Return to index | ||||||||
Order | Gene | Description | ref_hepatocyte | HepG2 | HepG2.C3A | HuH.7 | SNU475 | THLE | liver |
1 | PCK1 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | [1] | -9.09[2] | -4.87[3] | -13.00[4] | [5] | -16.79[6] | 0.23[7] |
2 | CEBPD | CCAAT/enhancer-binding protein delta | [8] | -4.52[9] | -2.08[10] | -1.87[11] | -3.71[12] | -2.72[13] | -2.71[14] |
3 | CEBPB | CCAAT/enhancer-binding protein beta | [15] | -1.21[16] | -1.88[17] | -2.31[18] | -1.51[19] | -0.52[20] | -2.51[21] |
4 | CEBPA | CCAAT/enhancer-binding protein alpha | [22] | 0.30[23] | -0.94[24] | 0.82[25] | -7.12[26] | -7.40[27] | -0.87[28] |
5 | SREBF1 | Sterol regulatory element-binding protein 1 | [29] | -0.81[30] | -0.56[31] | -0.47[32] | -1.64[33] | -1.40[34] | -0.34[35] |
6 | CCNC | Cyclin-C | [36] | -0.96[37] | 0.39[38] | -0.56[39] | -1.19[40] | -0.89[41] | -0.94[42] |
7 | MED8 | Mediator of RNA polymerase II transcription subunit 8 | [43] | -0.75[44] | -1.05[45] | -1.38[46] | -1.31[47] | -1.60[48] | -1.75[49] |
8 | ANGPTL4 | Angiopoietin-related protein 4 | [50] | -1.75[51] | -2.75[52] | -2.75[53] | -3.06[54] | 0.97[55] | -0.35[56] |
9 | MED10 | Mediator of RNA polymerase II transcription subunit 10 | [57] | -2.05[58] | -2.07[59] | -3.37[60] | -1.44[61] | -1.06[62] | -2.87[63] |
10 | CDK4 | Cyclin-dependent kinase 4 | [64] | 1.29[65] | 1.84[66] | 1.02[67] | 0.08[68] | 0.79[69] | -1.67[70] |
11 | THRAP3 | Thyroid hormone receptor-associated protein 3 | [71] | 0.74[72] | 0.62[73] | 0.63[74] | 0.49[75] | 0.77[76] | 0.34[77] |
12 | MED28 | Mediator of RNA polymerase II transcription subunit 28 | [78] | -0.65[79] | -0.39[80] | -0.44[81] | -1.59[82] | -1.91[83] | -3.16[84] |
13 | RELA | Transcription factor p65 | [85] | 0.10[86] | -0.44[87] | -0.76[88] | -0.15[89] | -0.19[90] | -1.71[91] |
14 | RXRA | Retinoic acid receptor RXR-alpha | [92] | -0.09[93] | -0.33[94] | 0.06[95] | -0.09[96] | -0.36[97] | 1.32[98] |
15 | MED11 | Mediator of RNA polymerase II transcription subunit 11 | [99] | -2.11[100] | -1.53[101] | -1.81[102] | -2.36[103] | -2.81[104] | -2.63[105] |
16 | HDAC3 | Histone deacetylase 3 | [106] | 0.44[107] | 0.46[108] | -0.19[109] | -0.15[110] | 0.07[111] | -1.23[112] |
17 | MED6 | Mediator of RNA polymerase II transcription subunit 6 | [113] | -0.68[114] | -1.00[115] | -1.85[116] | -0.81[117] | -0.94[118] | -2.59[119] |
18 | SREBF2 | Sterol regulatory element-binding protein 2 | [120] | 1.23[121] | 2.04[122] | 2.77[123] | -0.43[124] | -0.09[125] | 0.64[126] |
19 | MED4 | Mediator of RNA polymerase II transcription subunit 4 | [127] | -0.79[128] | -0.42[129] | -0.45[130] | -1.38[131] | -0.63[132] | -1.38[133] |
20 | MED15 | Mediator of RNA polymerase II transcription subunit 15 | [134] | 1.10[135] | 0.26[136] | -0.38[137] | 1.17[138] | 1.03[139] | -1.30[140] |
21 | MED29 | Mediator of RNA polymerase II transcription subunit 29 | [141] | 0.20[142] | 0.10[143] | -0.09[144] | 0.40[145] | 0.26[146] | -0.45[147] |
22 | CARM1 | Histone-arginine methyltransferase CARM1 | [148] | 1.42[149] | 0.83[150] | 0.70[151] | -0.35[152] | 0.51[153] | -1.85[154] |
23 | ZNF638 | Zinc finger protein 638 | [155] | -0.33[156] | 1.74[157] | 1.17[158] | 1.20[159] | 0.99[160] | 1.39[161] |
24 | NCOR1 | Nuclear receptor corepressor 1 | [162] | 1.04[163] | 1.51[164] | 1.70[165] | 1.47[166] | 1.57[167] | 1.97[168] |
25 | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | [169] | 0.63[170] | 0.28[171] | -0.39[172] | -0.35[173] | 0.62[174] | -0.38[175] |
26 | MED16 | Mediator of RNA polymerase II transcription subunit 16 | [176] | 0.35[177] | 0.22[178] | -0.51[179] | 0.05[180] | -0.05[181] | 0.39[182] |
27 | MED24 | Mediator of RNA polymerase II transcription subunit 24 | [183] | 1.82[184] | 0.96[185] | 1.46[186] | 0.78[187] | 1.15[188] | -0.21[189] |
28 | MED9 | Mediator of RNA polymerase II transcription subunit 9 | [190] | -0.16[191] | -0.75[192] | -0.94[193] | -1.29[194] | -0.68[195] | -1.60[196] |
29 | MED30 | Mediator of RNA polymerase II transcription subunit 30 | [197] | -1.77[198] | -1.28[199] | -3.39[200] | -1.34[201] | -2.36[202] | -2.49[203] |
30 | MED21 | Mediator of RNA polymerase II transcription subunit 21 | [204] | -0.53[205] | 0.22[206] | -0.12[207] | -0.48[208] | 0.75[209] | -0.86[210] |
31 | MED18 | Mediator of RNA polymerase II transcription subunit 18 | [211] | 0.16[212] | -0.31[213] | -0.61[214] | -0.07[215] | -0.88[216] | -1.39[217] |
32 | CDK8 | Cyclin-dependent kinase 8 | [218] | -0.89[219] | -0.37[220] | -1.76[221] | -0.60[222] | -0.93[223] | -2.59[224] |
33 | TBL1XR1 | F-box-like/WD repeat-containing protein TBL1XR1 | [225] | 1.04[226] | 1.55[227] | 1.73[228] | 2.31[229] | 1.93[230] | 2.04[231] |
34 | KLF4 | Krueppel-like factor 4 | [232] | -2.24[233] | -6.02[234] | -3.78[235] | -4.26[236] | 0.17[237] | -2.76[238] |
35 | MED27 | Mediator of RNA polymerase II transcription subunit 27 | [239] | -0.48[240] | -0.65[241] | -1.05[242] | -0.23[243] | -0.07[244] | -1.98[245] |
36 | NR2F2 | COUP transcription factor 2 | [246] | 0.16[247] | -0.93[248] | 0.31[249] | 1.87[250] | 1.24[251] | -0.01[252] |
37 | TBL1X | F-box-like/WD repeat-containing protein TBL1X | [253] | 1.30[254] | 1.67[255] | 2.77[256] | -4.50[257] | 1.05[258] | 0.91[259] |
38 | MED7 | Mediator of RNA polymerase II transcription subunit 7 | [260] | -1.64[261] | -0.86[262] | -1.53[263] | -1.09[264] | -1.06[265] | -1.68[266] |
39 | PPARA | Peroxisome proliferator-activated receptor alpha | [267] | 0.63[268] | 1.58[269] | 1.98[270] | -0.06[271] | -0.84[272] | 3.32[273] |
40 | MED1 | Mediator of RNA polymerase II transcription subunit 1 | [274] | 2.51[275] | 1.80[276] | 2.25[277] | 2.10[278] | 2.32[279] | 0.45[280] |
41 | MED19 | Mediator of RNA polymerase II transcription subunit 19 | [281] | -0.86[282] | -1.04[283] | -0.28[284] | 0.09[285] | -0.39[286] | -1.87[287] |
42 | PPARG | Peroxisome proliferator-activated receptor gamma | [288] | -0.13[289] | 1.46[290] | 1.51[291] | 0.75[292] | 0.78[293] | -1.21[294] |
43 | MED20 | Mediator of RNA polymerase II transcription subunit 20 | [295] | 1.12[296] | 1.10[297] | -0.11[298] | 1.44[299] | 0.27[300] | -0.79[301] |
44 | MED31 | Mediator of RNA polymerase II transcription subunit 31 | [302] | -1.42[303] | -0.84[304] | -1.25[305] | -1.20[306] | -0.73[307] | -2.02[308] |
45 | CCND3 | G1/S-specific cyclin-D3 | [309] | 0.91[310] | -0.18[311] | -2.27[312] | 3.56[313] | 2.80[314] | -0.18[315] |
46 | MED17 | Mediator of RNA polymerase II transcription subunit 17 | [316] | 1.27[317] | 1.05[318] | -0.11[319] | 0.97[320] | 1.04[321] | -0.99[322] |
47 | MED25 | Mediator of RNA polymerase II transcription subunit 25 | [323] | 1.01[324] | 0.50[325] | 0.41[326] | 1.21[327] | 0.98[328] | -1.90[329] |
48 | FAM120B | Constitutive coactivator of peroxisome proliferator-activated receptor gamma | 1.08[330] | 0.73[331] | -0.35[332] | 0.40[333] | 1.30[334] | 0.42[335] | |
49 | MED22 | Mediator of RNA polymerase II transcription subunit 22 | [336] | 1.44[337] | 1.38[338] | 0.79[339] | 1.66[340] | 1.43[341] | -0.53[342] |
50 | NCOA6 | Nuclear receptor coactivator 6 | [343] | 2.17[344] | 1.98[345] | 1.73[346] | 2.46[347] | 1.77[348] | 0.58[349] |
51 | NCOA3 | Nuclear receptor coactivator 3 | [350] | 2.68[351] | 2.05[352] | 1.90[353] | 3.00[354] | 2.01[355] | 1.82[356] |
52 | NCOR2 | Nuclear receptor corepressor 2 | [357] | 3.31[358] | 1.67[359] | 1.32[360] | 4.05[361] | 3.61[362] | 1.06[363] |
53 | MED13 | Mediator of RNA polymerase II transcription subunit 13 | [364] | 1.88[365] | 2.24[366] | 2.77[367] | 2.63[368] | 2.64[369] | 3.12[370] |
54 | EP300 | Histone acetyltransferase p300 | [371] | 2.68[372] | 2.24[373] | 2.68[374] | 2.47[375] | 2.58[376] | 1.92[377] |
55 | TGFB1 | Transforming growth factor beta-1 | [378] | 3.43[379] | 2.36[380] | -0.84[381] | 3.74[382] | 3.03[383] | -2.06[384] |
56 | MED14 | Mediator of RNA polymerase II transcription subunit 14 | [385] | 1.52[386] | 1.67[387] | 2.11[388] | 3.04[389] | 2.91[390] | 1.14[391] |
57 | TGS1 | Trimethylguanosine synthase | [392] | 0.56[393] | 0.96[394] | 1.04[395] | 1.62[396] | 1.51[397] | 0.15[398] |
58 | MED23 | Mediator of RNA polymerase II transcription subunit 23 | [399] | 1.56[400] | 2.23[401] | 1.56[402] | 2.06[403] | 1.81[404] | 1.44[405] |
59 | NCOA1 | Nuclear receptor coactivator 1 | [406] | 0.43[407] | 0.96[408] | 0.70[409] | 1.69[410] | 1.20[411] | 1.82[412] |
60 | PLIN1 | Perilipin-1 | [413] | -3.90[414] | -3.55[415] | -4.94[416] | -4.34[417] | -4.97[418] | 1.18[419] |
61 | PPARGC1 | Peroxisome proliferator-activated receptor gamma coactivator 1-alpha | -1.13[420] | 1.73[421] | -9.50[422] | 0.66[423] | -2.58[424] | 2.60[425] | |
62 | CREBBP | CREB-binding protein | [426] | 2.86[427] | 2.04[428] | 2.20[429] | 2.66[430] | 2.72[431] | 2.40[432] |
63 | CD36 | Platelet glycoprotein 4 | [433] | 1.30[434] | 0.59[435] | -4.95[436] | 3.08[437] | -5.86[438] | 2.25[439] |
64 | MED13L | Mediator of RNA polymerase II transcription subunit 13-like | [440] | 2.34[441] | 2.65[442] | 3.20[443] | 3.35[444] | 3.03[445] | 2.93[446] |
65 | KLF5 | Krueppel-like factor 5 | [447] | 1.58[448] | -1.06[449] | 3.33[450] | 0.94[451] | 1.45[452] | -3.94[453] |
66 | MED26 | Mediator of RNA polymerase II transcription subunit 26 | [454] | 0.54[455] | 0.46[456] | 1.20[457] | 0.25[458] | 1.19[459] | -0.95[460] |
67 | CHD9 | Chromodomain-helicase-DNA-binding protein 9 | [461] | 1.29[462] | 3.35[463] | 2.14[464] | 2.28[465] | 3.36[466] | 4.10[467] |
68 | NCOA2 | Nuclear receptor coactivator 2 | [468] | 1.54[469] | 2.32[470] | 3.69[471] | 3.10[472] | 1.45[473] | 3.77[474] |
69 | MED12 | Mediator of RNA polymerase II transcription subunit 12 | [475] | 2.97[476] | 2.24[477] | 2.18[478] | 3.43[479] | 2.72[480] | 1.91[481] |
70 | ZNF467 | Zinc finger protein 467 | [482] | -3.51[483] | -6.94[484] | -1.75[485] | 1.85[486] | -0.07[487] | -0.39[488] |
71 | CDK19 | Cyclin-dependent kinase 19 | [489] | 2.32[490] | 3.49[491] | 1.30[492] | 2.78[493] | 2.72[494] | 0.97[495] |
72 | SLC2A4 | Solute carrier family 2, facilitated glucose transporter member 4 | [496] | 1.79[497] | 2.00[498] | 2.16[499] | -2.23[500] | -2.90[501] | 0.61[502] |
73 | EGR2 | E3 SUMO-protein ligase EGR2 | [503] | -1.77[504] | -3.93[505] | -4.79[506] | -1.73[507] | -1.40[508] | -1.32[509] |
74 | SMARCD3 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfa | 1.43[510] | -0.27[511] | 1.32[512] | 3.16[513] | 3.41[514] | 0.53[515] | |
75 | LPL | Lipoprotein lipase | [516] | [517] | [518] | -7.94[519] | 0.47[520] | -3.11[521] | -1.07[522] |
76 | TNF | Tumor necrosis factor | [523] | 1.06[524] | -1.11[525] | -6.16[526] | -2.32[527] | -5.48[528] | -2.72[529] |
77 | ADIPOQ | Adiponectin | [530] | -1.55[531] | -1.39[532] | -2.07[533] | -0.97[534] | -1.91[535] | -1.58[536] |
78 | FABP4 | Fatty acid-binding protein, adipocyte | [537] | [538] | [539] | [540] | [541] | -5.07[542] | 2.33[543] |
79 | LEP | Leptin | [544] | -1.37[545] | -0.42[546] | -1.42[547] | -0.95[548] | -2.22[549] | 1.47[550] |
80 | HELZ2 | Helicase with zinc finger domain 2 | [551] | [552] | [553] | [554] | [555] | [556] | [557] |
81 | ADIRF | Adipogenesis regulatory factor | [558] | [559] | [560] | [561] | [562] | [563] | [564] |
82 | WNT10B | Protein Wnt-10b | [565] | [566] | [567] | [568] | [569] | [570] | [571] |
83 | WNT1 | Proto-oncogene Wnt-1 | [572] | [573] | [574] | [575] | [576] | [577] | [578] |
84 | EBF1 | Transcription factor COE1 | [579] | [580] | [581] | [582] | [583] | [584] | [585] |